{"id":44131,"date":"2022-05-19T17:01:14","date_gmt":"2022-05-19T15:01:14","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/melanoma-research-alliance-announces-13-million-in-grants-to-advance-melanoma-prevention-detection-treatment\/"},"modified":"2022-05-19T17:01:14","modified_gmt":"2022-05-19T15:01:14","slug":"melanoma-research-alliance-announces-13-million-in-grants-to-advance-melanoma-prevention-detection-treatment","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/melanoma-research-alliance-announces-13-million-in-grants-to-advance-melanoma-prevention-detection-treatment\/","title":{"rendered":"Melanoma Research Alliance Announces $13 Million in Grants to Advance Melanoma Prevention, Detection & Treatment"},"content":{"rendered":"
\n

WASHINGTON–(BUSINESS WIRE)–Coinciding with Melanoma Awareness Month, the Melanoma Research Alliance (MRA), the largest non-profit funder of melanoma research, today announced funding for 27 research grants totaling $13,046,774 to support new research aimed at advancing melanoma prevention, diagnosis and treatment. Melanoma is the deadliest form of skin cancer and the fifth most common cancer in the United States.\n<\/p>\n

<\/a><\/p>\n

\nThe grants will support 11 Team Science Awards, 10 Young Investigator Awards, and 6 Pilot Awards. MRA grant awards back development of innovative ideas that offer the promise of rapidly improving outcomes for melanoma patients.\n<\/p>\n

\nThis year\u2019s grant awards focus on a variety of approaches, including the use of novel cellular barcodes to identify causes \u2013 and possible treatments \u2013 of resistant disease; research focused on rare melanoma subtypes ways to improve response to existing checkpoint immunotherapies; and two pilot awards co-funded with the Michael J. Fox Foundation to study the connection between melanoma and Parkinson\u2019s Disease.\n<\/p>\n

\n\u201cThese scientific proposals selected this year for funding by MRA\u2019s expert Grant Review Committee are exceptional,\u201d said MRA Chief Executive Officer Marc Hurlbert, PhD. \u201cWe are at a pivotable moment in the fight against melanoma. We are thrilled to support this critical work with the hope of benefiting all patients and families dealing with melanoma, and preventing countless more from having to do so.\u201d\n<\/p>\n

\n2022 Melanoma Research Alliance Grant Awards<\/b>\n<\/p>\n

\nTeam Science Awards<\/b>\n<\/p>\n

\nTargeting Oncogenic Gaq in Uveal Melanoma
\n
<\/b>MRA Team Science Award
\n
<\/i>Boris Bastian, MD, The University of California, San Francisco\n<\/p>\n

\nIdentification & Validation of Novel Druggable Targets in Mucosal Melanoma
\n
<\/b>MRA Team Science Award
\n
<\/i>Genevieve Boland MD, PhD, Massachusetts General Hospital\n<\/p>\n

\nTargeting Epigenetics to Enhance Anti-Melanoma Immunity
\n
<\/b>Leveraged Finance Fights Melanoma \u2013 MRA Team Science Award
\n
<\/i>Marcus Bosenberg MD, PhD, Yale University\n<\/p>\n

\nTargeting RNA Processing to Enhance Mucosal Melanoma Immunotherapy
\n
<\/b>MRA Team Science Award
\n
<\/i>Rotem Karni PhD, Hebrew University of Jerusalem\n<\/p>\n

\nHarnessing B Cell Checkpoints in Melanoma
\n
<\/b>MRA Team Science Award, collaboratively funded by Brigham and Women’s Hospital and The University of Texas MD Anderson Cancer Center
\n
<\/i>Vijay Kuchroo DVM, PhD, Brigham and Women’s Hospital, Inc.\n<\/p>\n

\nTargeting Chromothripsis to Suppress Metastasis and Therapy Resistance
\n
<\/b>MRA Team Science Award
\n
<\/i>Roger Lo MD, PhD, The University of California, Los Angeles\n<\/p>\n

\nCellular Barcoding to Define Melanoma Drug Resistance and Cell of Origin
\n
<\/b>MRA Team Science Award for Women in Melanoma Research
\n
<\/i>Elizabeth E. Patton PhD, University of Edinburgh\n<\/p>\n

\nIdentifying Public Neoantigens, their TCRs and their Rules of Engagement
\n
<\/b>MRA Team Science Award
\n
<\/i>Yardena Samuels PhD, Weizmann Institute of Science\n<\/p>\n

\nImproving Immunological Memory During Anti-PD-1 Immunotherapy
\n
<\/b>MRA Team Science Award, collaboratively funded by Harvard Medical School and Dana-Farber Cancer Institute
\n
<\/i>Arlene Sharpe MD, PhD, Harvard Medical School\n<\/p>\n

\nNoninvasive Prediction of Severe Toxicity from Immune Checkpoint Blockade
\n
<\/b>MRA Team Science Award, collaboratively funded by Yale University, Washington University, and Stanford University
\n
<\/i>Mario Sznol MD, Yale University\n<\/p>\n

\nTeam Science Academic-Industry Partnership Award<\/b>\n<\/p>\n

\nAnalytical and Clinical Validation of a Multiplex IF Biomarker for Anti-PD1
\n
<\/b>MRA Team Science Academic-Industry Partnership Award
\n
<\/i>Janis Taube MD, Johns Hopkins University School of Medicine\n<\/p>\n

\nYoung Investigator Awards<\/b>\n<\/p>\n

\nNew Genetic Tools to Understand the Role of M6A in Melanomagenesis
\n
<\/b>MRA Young Investigator Award
\n
<\/i>Claudio Alarcon PhD, Yale University, School of Medicine\n<\/p>\n

\nDecipher the Epigenetic Code Regulating Cellular Dynamics in Acral Melanoma
\n
<\/b>MRA Young Investigator Award
\n
<\/i>Junyue Cao PhD, The Rockefeller University\n<\/p>\n

\nTargeting Anti-Tumor Immunity in Anatomically Distinct Mucosal Melanomas
\n
<\/b>MRA Young Investigator Award for Women in Melanoma Research
\n
<\/i>Kasey Couts PhD, University of Colorado Denver\n<\/p>\n

\nInvestigating Lipid Kinase Pip4k2c in Regulating Anti-Tumor Immunity
\n
<\/b>Bristol Myers Squibb \u2013 MRA Young Investigator Award
\n
<\/i>Karen Dixon PhD, Brigham and Women’s Hospital\n<\/p>\n

\nMechanisms and Relevance of Treg Expansion after PD-1 Blockade in Melanoma
\n
<\/b>Bristol Myers Squibb \u2013 MRA Young Investigator Award
\n
<\/i>Francesco Marangoni PhD, The University of California, Irvine\n<\/p>\n

\nInterfering with Early Cell State Transitions to Prevent Drug Tolerance
\n
<\/b>The Wayne Stinchcomb Big Orange Melanoma Foundation \u2013 MRA Young Investigator Award
\n
<\/i>Florian Rambow PhD, Essen University Hospital\n<\/p>\n

\nInterrogating Epigenetic Regulation of PD1 in Melanoma-Infiltrating T Cells
\n
<\/b>Leveraged Finance Fights Melanoma \u2013 MRA Young Investigator Award in memory of Michael Konigsberg
\n
<\/i>Debattama Sen PhD, Massachusetts General Hospital\n<\/p>\n

\nTumor-Stroma Metabolic Crosstalk in Melanoma Brain Metastases
\n
<\/b>Tara Miller Melanoma Foundation \u2013 MRA Young Investigator Award
\n
<\/i>Inna Smalley PhD, H. Lee Moffitt Cancer Center & Research Institute\n<\/p>\n

\nInvestigating the role of FGL1\/LAG-3 Axis in Melanoma Immunity
\n
<\/b>Bristol Myers Squibb \u2013 MRA Young Investigator Award
\n
<\/i>Jun Wang PhD, New York University School of Medicine\n<\/p>\n

\nmRNA-Based Re-Programming of Terminally Differentiated TILs
\n
<\/b>MRA Young Investigator Award
\n
<\/i>Yochai Wolf PhD, The Sheba Fund for Health Service and Research\n<\/p>\n

\nPilot Awards<\/b>\n<\/p>\n

\nA Strategy to Identify the Basis of Melanoma and Parkinson’s Comorbidity
\n
<\/b>The Michael J. Fox Foundation \u2013 MRA Pilot Award
\n
<\/i>Deanna L. Benson PhD, Icahn School of Medicine at Mount Sinai\n<\/p>\n

\nInvestigating ARID2 as a Suppressor of Melanoma Metastasis
\n
<\/b>MRA Pilot Award for Women in Melanoma Research
\n
<\/i>Emily Bernstein PhD, Icahn School of Medicine at Mount Sinai\n<\/p>\n

\nCombined Intrathecal Immunotherapeutic Strategies for Melanoma LMD
\n
<\/b>MRA Pilot Award
\n
<\/i>Sherise Ferguson MD, University of Texas MD Anderson Cancer Center\n<\/p>\n

\nNovel Mouse Models of Uveal Melanoma
\n
<\/b>MRA Pilot Award
\n
<\/i>Florian Karreth PhD, H. Lee Moffitt Cancer Center & Research Institute, Inc\n<\/p>\n

\nThe Role of APC Mutations in Melanoma Brain Metastasis
\n
<\/b>Leveraged Finance Fights Melanoma \u2013 MRA Pilot Award
\n
<\/i>James Robinson PhD, The University of Minnesota, Twin Cities\n<\/p>\n

\nAlpha-Synuclein\u2019s Role in Melanoma Formation and Metastasis
\n
<\/b>The Michael J. Fox Foundation \u2013 MRA Pilot Award
\n
<\/i>Vivek Unni MD, PhD, Oregon Health & Science University\n<\/p>\n

\nAbout Melanoma Research Alliance (MRA)<\/b>\n<\/p>\n

\nThe Melanoma Research Alliance exists to accelerate treatment options and find a cure for melanoma. As the largest nonprofit funder of melanoma research, it has dedicated over $143 million and leveraged an additional $417 million in collaborative and follow-on funding towards its mission. Through its support, MRA has championed revolutions in immunotherapy, targeted therapies, novel combinations and diagnostics. Due to the ongoing support of its founders, 100 percent of donations to MRA go directly to its melanoma research program. MRA’s ability to fund wide-ranging research in melanoma is amplified by unique collaborations and partnerships with individuals, private foundations, and corporations. Visit http:\/\/www.CureMelanoma.org<\/a> for more information.\n<\/p>\n

Contacts<\/b> <\/p>\n

\nCody R. Barnett, Director of Communications
\n
M: (717) 880-7100
\n
E-mail: cbarnett@curemelanoma.org<\/a>\n<\/p>\n

\nAnreder & Company
\n
(212) 532-3232
\n
Steven S. Anreder \u2013 steven.anreder@anreder.com<\/a>
Michael Wichman — michael.wichman@anreder.com<\/a>\n<\/p>\n

\n\u00a0\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

WASHINGTON–(BUSINESS WIRE)–Coinciding with Melanoma Awareness Month, the Melanoma Research Alliance (MRA), the largest non-profit funder of melanoma research, today announced funding for 27 research grants totaling $13,046,774 to support new research aimed at advancing melanoma prevention, diagnosis and treatment. Melanoma is the deadliest form of skin cancer and the fifth most common cancer in the … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-44131","6":"format-standard","7":"category-industry"},"yoast_head":"\nMelanoma Research Alliance Announces $13 Million in Grants to Advance Melanoma Prevention, Detection & Treatment - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/melanoma-research-alliance-announces-13-million-in-grants-to-advance-melanoma-prevention-detection-treatment\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Melanoma Research Alliance Announces $13 Million in Grants to Advance Melanoma Prevention, Detection & Treatment - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"WASHINGTON–(BUSINESS WIRE)–Coinciding with Melanoma Awareness Month, the Melanoma Research Alliance (MRA), the largest non-profit funder of melanoma research, today announced funding for 27 research grants totaling $13,046,774 to support new research aimed at advancing melanoma prevention, diagnosis and treatment. 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