{"id":44371,"date":"2022-05-26T12:01:22","date_gmt":"2022-05-26T10:01:22","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/"},"modified":"2022-05-26T12:01:22","modified_gmt":"2022-05-26T10:01:22","slug":"visual-system-brain-development-implicated-in-infants-who-develop-autism","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/","title":{"rendered":"Visual System Brain Development Implicated in Infants who Develop Autism"},"content":{"rendered":"<div>\n<p class=\"bwalignc\">\n<i>UNC School of Medicine researchers used MRI to document crucial differences in the visual processing system in the brains of infants who went on to be diagnosed with autism.<\/i>\n<\/p>\n<p>CHAPEL HILL, N.C.&#8211;(BUSINESS WIRE)&#8211;For the first time, scientists have found that brain differences in the visual brain systems of infants who later are diagnosed with autism are associated with inherited genetic factors.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20220526005014\/en\/1466171\/5\/girault_autism_baby_image.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20220526005014\/en\/1466171\/21\/girault_autism_baby_image.jpg\"><\/a><br \/><a href=\"https:\/\/mms.businesswire.com\/media\/20220526005014\/en\/597070\/5\/som_logo_PMS542.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20220526005014\/en\/597070\/21\/som_logo_PMS542.jpg\"><\/a><\/p>\n<p>\nPublished in the <i>American Journal of Psychiatry<\/i>, this research shows that brain changes in the size, white matter integrity and functional connectivity of the visual processing systems of six-month olds are evident well before they show symptoms of autism as toddlers. Moreover, the presence of brain changes in the visual system is associated with the severity of autism traits in their older siblings.\n<\/p>\n<p>\nLed by Jessica Girault, PhD, assistant professor of psychiatry at the UNC School of Medicine, this is the first research to observe that infants with older siblings who have autism and who themselves later develop autism as toddlers, have specific biological differences in visual processing regions of the brain, and that these brain characteristics precede the appearance of autistic symptoms. The presence of those visual processing differences is related to how pronounced the autism traits are in the older siblings.\n<\/p>\n<p>\n\u201cWe\u2019re beginning to parse differences in infant brain development that might be related to genetic factors,\u201d said Girault, who is also a member of the Carolina Institute of Developmental Disabilities (CIDD). \u201cUsing magnetic resonance imaging (MRI), we studied selected structures of brain, the functional relationship between key brain regions, and the microstructure of white matter connections between those brain regions. Findings from all three pointed us to the discovery of unique differences in the visual systems of infants who later developed autism.\u201d\n<\/p>\n<p>\nAs part of the NIH-funded Infant Brain Imaging Study (IBIS) Network, UNC-Chapel Hill and Washington University researchers spearheaded this first-of-its-kind study.\n<\/p>\n<p>\n<b>Behind Baby\u2019s Eyes<\/b>\n<\/p>\n<p>\nWhen parents and babies bond, when they lock eyes and experience their world together day after day, it\u2019s not just cute; it\u2019s how babies learn to interpret subtle cues about their environment. It\u2019s the way babies learn to relate a caregiver\u2019s behaviors to their own. This visual rhythm through the first years of life is crucial to cognitive, emotional, and social development. In babies who go on to develop autism, this research suggests that something goes awry in the brain\u2019s visual system that impacts this visual interplay.\n<\/p>\n<p>\nIn recent years, IBIS Network researchers have used MRI to document brain differences in babies that later develop autism in the second year of life. In 2020, Girault\u2019s research showed that younger infant siblings were much more likely to develop autism if their older autistic siblings had higher levels of autistic traits.\n<\/p>\n<p>\n\u201cThis suggests that these autistic traits tell us <i>something<\/i> about the strength of genetic factors for autism within a family,\u201d Girault said. \u201cBut we couldn\u2019t say much more beyond that. This current study takes our work a step forward.\u201d\n<\/p>\n<p>\nFor this study, the Infant Brain Imaging Study (IBIS) Network researchers recruited 384 pairs of siblings. The older child in each pair had already been diagnosed with autism, which put the infant sibling at a higher likelihood of developing autism. Then the researchers used various MRI approaches to study in detail the brains of the younger siblings at six, 12, and 24 months of age.\n<\/p>\n<p>\nThe researchers measured brain volume, area of the brain surface, in the region of the brain involved with vision (the occipital cortex) \u2013 structures that this research team had previously shown to be altered in babies who went on to develop autism as toddlers. They also examined the white matter microstructure of the splenium, a structure the researchers previously showed was related to how quickly infants orient to visual stimuli in their environments. At the same time, researchers documented the level of autistic traits in the older autistic siblings of those infants.\n<\/p>\n<p>\nIn six-month olds who went on to develop autism at 24 months of age, the researchers found that brain features involved with the structure of the visual system differed from infants who did not develop autism. Using this information, the research team then looked at networks throughout the brain and found significantly weaker functional connections between specific brain networks that linked to the visual system.\n<\/p>\n<p>\nGirault and colleagues pinpointed brain differences in two parts of the visual processing system \u2013 the occipital gyrus, which is important for object recognition, and the splenium, which is important for communicating between different hemispheric parts of the visual system. The splenium is also crucial for quickly orienting our attention to things we see around us.\n<\/p>\n<p>\n\u201cIt is particularly notable that we were able to demonstrate associations between brain findings in infants and the behavior of their older siblings with autism,\u201d said co-senior author John R. Pruett, Jr., MD, PhD, professor of psychiatry at the Washington University School of Medicine. \u201cThe convergence of brain-wide, data-driven fcMRI results with the structural and diffusion findings strengthens our confidence in future replication of these discoveries, which could be tested in the<sup> <\/sup>new cohort of 250 high-familial likelihood infants we are presently recruiting.\u201d\n<\/p>\n<p>\nCo-senior author Joe Piven, MD, CIDD director, added, \u201cWe think aberrant visual circuitry is a fundamental cog in the cascade of events leading to later autism. We think this circuitry alters how infants experience the world, and how they experience the world<i> <\/i>alters how their brains subsequently develop. It\u2019s this secondary altered brain development that may result in what we call autism that typically emerges in the latter part of the first and second years of life.\u201d\n<\/p>\n<p>\nMore research is needed, but this study points in the direction of behavioral interventions aimed at the visual and related brain systems in the first year of life in infants at higher likelihood of developing autism based on inherited risk factors. Such interventions would aim to decrease the likelihood of children developing certain, more severe autism traits.\n<\/p>\n<p>\n<i>Co-senior authors are Joe Piven, MD, CIDD director and Thomas E. Castelloe Distinguished Professor of Psychiatry and Pediatrics at the UNC School of Medicine; John Constantino, MD, the Blanche F. Ittleson Professor of Psychiatry and Pediatrics and at the Washington University School of Medicine and Psychiatrist-in-Chief at the St. Louis Children\u2019s Hospital; and John R. Pruett, Jr., MD, PhD, professor of psychiatry at the Washington University School of Medicine.<\/i>\n<\/p>\n<p>\n<i>This research was supported by grants from the National Institutes of Health (K01-MH122779, R01-HD055741, T32-HD040127, P30-HD003110, R01-MH118362, MH118362-02S1, and P30-NS098577), and by the Simons Foundation (140209).<\/i>\n<\/p>\n<p>\n<i>The authors are grateful to all the families and children who participated in the Infant Brain Imaging Study (IBIS) study. The IBIS Network is an NIH-funded Autism Center of Excellence project and consists of a consortium of nine universities in the United States and Canada.<\/i>\n<\/p>\n<p>\n<b><i>About UNC School of Medicine<\/i><\/b>\n<\/p>\n<p>\n<i>The UNC School of Medicine (SOM) is the state\u2019s largest medical school, graduating approximately 180 new physicians each year. It is consistently ranked among the top medical schools in the US, including 3<sup>rd<\/sup> overall for primary care by US News &amp; World Report, and 6<sup>th<\/sup> for research among public universities. More than half of the school\u2019s 1,700 faculty members served as principal investigators on active research awards in 2021. Two UNC SOM faculty members have earned Nobel Prize awards.<\/i>\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\n<i><a target=\"_blank\" href=\"&#x6d;&#x61;&#105;&#108;to&#x3a;&#x6d;&#x61;&#114;k&#46;&#x64;&#x65;&#x72;&#101;&#119;i&#x63;&#x7a;&#x40;&#117;&#110;c&#x68;&#x65;&#x61;&#108;&#116;h&#46;&#x75;&#x6e;&#x63;&#46;ed&#x75;\" rel=\"nofollow noopener\" shape=\"rect\">Mark Derewicz<\/a>, 919-923-0959<\/i>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>UNC School of Medicine researchers used MRI to document crucial differences in the visual processing system in the brains of infants who went on to be diagnosed with autism. CHAPEL HILL, N.C.&#8211;(BUSINESS WIRE)&#8211;For the first time, scientists have found that brain differences in the visual brain systems of infants who later are diagnosed with autism &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-44371","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Visual System Brain Development Implicated in Infants who Develop Autism - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Visual System Brain Development Implicated in Infants who Develop Autism - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"UNC School of Medicine researchers used MRI to document crucial differences in the visual processing system in the brains of infants who went on to be diagnosed with autism. CHAPEL HILL, N.C.&#8211;(BUSINESS WIRE)&#8211;For the first time, scientists have found that brain differences in the visual brain systems of infants who later are diagnosed with autism ... [Read more...]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/\" \/>\n<meta property=\"og:site_name\" content=\"Pharma Trend\" \/>\n<meta property=\"article:published_time\" content=\"2022-05-26T10:01:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mms.businesswire.com\/media\/20220526005014\/en\/1466171\/21\/girault_autism_baby_image.jpg\" \/>\n<meta name=\"author\" content=\"Business Wire\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Business Wire\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/\"},\"author\":{\"name\":\"Business Wire\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/person\\\/02d41342c7a74fa7f0032bb35ef0bb24\"},\"headline\":\"Visual System Brain Development Implicated in Infants who Develop Autism\",\"datePublished\":\"2022-05-26T10:01:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/\"},\"wordCount\":1235,\"publisher\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20220526005014\\\/en\\\/1466171\\\/21\\\/girault_autism_baby_image.jpg\",\"articleSection\":[\"Industry\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/\",\"url\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/\",\"name\":\"Visual System Brain Development Implicated in Infants who Develop Autism - Pharma Trend\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20220526005014\\\/en\\\/1466171\\\/21\\\/girault_autism_baby_image.jpg\",\"datePublished\":\"2022-05-26T10:01:22+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/#primaryimage\",\"url\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20220526005014\\\/en\\\/1466171\\\/21\\\/girault_autism_baby_image.jpg\",\"contentUrl\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20220526005014\\\/en\\\/1466171\\\/21\\\/girault_autism_baby_image.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/visual-system-brain-development-implicated-in-infants-who-develop-autism\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Visual System Brain Development Implicated in Infants who Develop Autism\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/\",\"name\":\"Pharma Trend\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#organization\",\"name\":\"Pharma Trend\",\"url\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Pharma Trend\"},\"image\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/person\\\/02d41342c7a74fa7f0032bb35ef0bb24\",\"name\":\"Business Wire\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Visual System Brain Development Implicated in Infants who Develop Autism - Pharma Trend","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/","og_locale":"en_US","og_type":"article","og_title":"Visual System Brain Development Implicated in Infants who Develop Autism - Pharma Trend","og_description":"UNC School of Medicine researchers used MRI to document crucial differences in the visual processing system in the brains of infants who went on to be diagnosed with autism. CHAPEL HILL, N.C.&#8211;(BUSINESS WIRE)&#8211;For the first time, scientists have found that brain differences in the visual brain systems of infants who later are diagnosed with autism ... [Read more...]","og_url":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/","og_site_name":"Pharma Trend","article_published_time":"2022-05-26T10:01:22+00:00","og_image":[{"url":"https:\/\/mms.businesswire.com\/media\/20220526005014\/en\/1466171\/21\/girault_autism_baby_image.jpg","type":"","width":"","height":""}],"author":"Business Wire","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Business Wire","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/#article","isPartOf":{"@id":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/"},"author":{"name":"Business Wire","@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/person\/02d41342c7a74fa7f0032bb35ef0bb24"},"headline":"Visual System Brain Development Implicated in Infants who Develop Autism","datePublished":"2022-05-26T10:01:22+00:00","mainEntityOfPage":{"@id":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/"},"wordCount":1235,"publisher":{"@id":"https:\/\/pharma-trend.com\/en\/#organization"},"image":{"@id":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/#primaryimage"},"thumbnailUrl":"https:\/\/mms.businesswire.com\/media\/20220526005014\/en\/1466171\/21\/girault_autism_baby_image.jpg","articleSection":["Industry"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/","url":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/","name":"Visual System Brain Development Implicated in Infants who Develop Autism - Pharma Trend","isPartOf":{"@id":"https:\/\/pharma-trend.com\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/#primaryimage"},"image":{"@id":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/#primaryimage"},"thumbnailUrl":"https:\/\/mms.businesswire.com\/media\/20220526005014\/en\/1466171\/21\/girault_autism_baby_image.jpg","datePublished":"2022-05-26T10:01:22+00:00","breadcrumb":{"@id":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/#primaryimage","url":"https:\/\/mms.businesswire.com\/media\/20220526005014\/en\/1466171\/21\/girault_autism_baby_image.jpg","contentUrl":"https:\/\/mms.businesswire.com\/media\/20220526005014\/en\/1466171\/21\/girault_autism_baby_image.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/pharma-trend.com\/en\/visual-system-brain-development-implicated-in-infants-who-develop-autism\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/pharma-trend.com\/en\/"},{"@type":"ListItem","position":2,"name":"Visual System Brain Development Implicated in Infants who Develop Autism"}]},{"@type":"WebSite","@id":"https:\/\/pharma-trend.com\/en\/#website","url":"https:\/\/pharma-trend.com\/en\/","name":"Pharma Trend","description":"","publisher":{"@id":"https:\/\/pharma-trend.com\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/pharma-trend.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/pharma-trend.com\/en\/#organization","name":"Pharma Trend","url":"https:\/\/pharma-trend.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Pharma Trend"},"image":{"@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/person\/02d41342c7a74fa7f0032bb35ef0bb24","name":"Business Wire"}]}},"_links":{"self":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/posts\/44371","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/comments?post=44371"}],"version-history":[{"count":0,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/posts\/44371\/revisions"}],"wp:attachment":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/media?parent=44371"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/categories?post=44371"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/tags?post=44371"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}