{"id":45186,"date":"2022-06-16T20:01:37","date_gmt":"2022-06-16T18:01:37","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/wisdom-panel-publishes-largest-ever-genetic-screening-studies-of-cats-and-dogs\/"},"modified":"2022-06-16T20:01:37","modified_gmt":"2022-06-16T18:01:37","slug":"wisdom-panel-publishes-largest-ever-genetic-screening-studies-of-cats-and-dogs","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/wisdom-panel-publishes-largest-ever-genetic-screening-studies-of-cats-and-dogs\/","title":{"rendered":"Wisdom Panel Publishes Largest-Ever Genetic Screening Studies of Cats and Dogs"},"content":{"rendered":"
\n

\nCombining genetic and clinical data, two studies encompassing more than one million pets provide foundation for understanding genetic basis of complex disorders like cancer and heart disease<\/i>\n<\/p>\n

<\/a><\/p>\n

PORTLAND, Ore.–(BUSINESS WIRE)–Wisdom Panel<\/a>, the world leader in pet genetics and maker of Wisdom Panel\u2122 pet DNA tests, announced today the publication of the two largest genetic screening studies of cats and dogs ever conducted.\n<\/p>\n

\nExamining more than one million pets across the two studies, the research team behind Wisdom Panel\u2122\u2014the most accurate pet DNA test on the market\u2014genotyped thousands of genetic variants, providing valuable insights into genetic diversity and variants associated with disease or traits in cats and dogs.\n<\/p>\n

\n\u201cThe results of these two studies, the largest genetic screening studies of cats and dogs ever completed, provide crucially important scientific knowledge for researchers, \u201d said Heidi Anderson, Ph.D. Senior Scientist, Feline Genetics at Wisdom Panel. \u201cNot only do they reinforce the importance of comprehensive genetic panel testing in personalized veterinary care, health research, and breeding programs, they help provide a foundation for uncovering the genetic basis of more complex disorders, ranging from cancer to heart disease, ultimately improving veterinary care and health outcomes for pets.\u201d\n<\/p>\n

\nConducted in partnership with the University of Helsinki, the study of domestic cat DNA\u2014Genetic epidemiology of blood type, disease and trait variants, and genome-wide genetic diversity in over 11,000 domestic cats<\/a><\/i>, published as an original research article in the peer-reviewed journal PLOS Genetics<\/i>\u2014identified disease-causing variants in new breeds, finding that 13 genetic variants associated with disease in cats are present in more pedigreed breeds than previously thought. However, because of selective breeding programs and the prevalence of genetic screening for known disease variants, some variants are declining in frequency in breeds regularly screened for the genetic markers.\n<\/p>\n

\nThe researchers genotyped over 11,000 domestic cats for 87 genetic variants associated with disease, blood type or physical appearance, finding 13 previously undocumented disease-causing variants in 47 breeds or breed types. The non-pedigreed cats were on average more diverse compared to all pedigreed cats and three disease-associated genetic variants were observed in non-pedigreed cats only.\n<\/p>\n

\nWisdom Panel has also conducted the largest-ever single study of dogs to date\u2014Genetic prevalence and clinical relevance of canine Mendelian disease variants in over one million dogs<\/a><\/span><\/i>\u2014with more than one million representative dogs selected from the company\u2019s existing DNA database of more than three million dogs.\n<\/p>\n

\nIn the study, available in preprint on bioRxiv, Wisdom Panel researchers examined the DNA of more than one million dogs and combined the results with clinical veterinary records to better understand the prevalence and distribution of 250 disease-causing variants in dogs regardless of their breed or ancestry. The study found that disease mutations are collectively common in all dogs and that many health issues are shared by both mixed breed and purebred dogs. The findings of the study also emphasize the importance of healthy breeding programs, namely that lower genetic diversity levels are associated with an increased risk for manifesting inherited diseases.\n<\/p>\n

\n\u201cIn addition to demonstrating the benefit of genetic screening in clinical veterinary and direct-to-consumer settings, the studies help raise awareness of various inherited conditions in cats and dogs and illustrate how genetic testing can be a proactive investment in a pet\u2019s health care,\u201d said Jonas Donner, Ph.D., Senior Scientist, Canine Genetics at Wisdom Panel who led the million-dog study.\n<\/p>\n

\nMore information about both studies and the impacts they have on the health of cats and dogs is available at www.wisdompanel.com<\/a>.\n<\/p>\n

\nAbout Wisdom Panel
\n
<\/b>The mission of Wisdom Panel, a division of Kinship Partners, Inc, is to strengthen the bond between pets and their people through world-leading insights powered by DNA. Wisdom Panel\u2122 pet DNA tests\u2014backed by scientific research\u2014can help pet parents plan better, care smarter, and love longer. For more than a decade, Wisdom Panel scientific research has contributed to state-of-the-art genetic tests for companion animals, revolutionizing personalized pet care. By unlocking the secrets of their dog or cat’s DNA, pet parents and veterinarians can work together to tailor wellness programs that fit the one-of-a-kind needs of their pets. More than 7,000 veterinarians worldwide recommend and offer Wisdom Panel products. For more information, visit www.wisdompanel.com<\/a>, and follow the Wisdom Panel brand on Facebook and Instagram.\n<\/p>\n

Contacts<\/b> <\/p>\n

\nMedia<\/b>
Ali Karp
\n
SourceCode Communications
\n
kinship@sourcecodecomms.com<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Combining genetic and clinical data, two studies encompassing more than one million pets provide foundation for understanding genetic basis of complex disorders like cancer and heart disease PORTLAND, Ore.–(BUSINESS WIRE)–Wisdom Panel, the world leader in pet genetics and maker of Wisdom Panel\u2122 pet DNA tests, announced today the publication of the two largest genetic screening … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-45186","6":"format-standard","7":"category-industry"},"yoast_head":"\nWisdom Panel Publishes Largest-Ever Genetic Screening Studies of Cats and Dogs - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/wisdom-panel-publishes-largest-ever-genetic-screening-studies-of-cats-and-dogs\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Wisdom Panel Publishes Largest-Ever Genetic Screening Studies of Cats and Dogs - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Combining genetic and clinical data, two studies encompassing more than one million pets provide foundation for understanding genetic basis of complex disorders like cancer and heart disease PORTLAND, Ore.–(BUSINESS WIRE)–Wisdom Panel, the world leader in pet genetics and maker of Wisdom Panel\u2122 pet DNA tests, announced today the publication of the two largest genetic screening ... 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