{"id":45249,"date":"2022-06-20T13:01:29","date_gmt":"2022-06-20T11:01:29","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/yourgene-health-launches-lightbench-detect-for-fetal-fraction-enrichment\/"},"modified":"2022-06-20T13:01:29","modified_gmt":"2022-06-20T11:01:29","slug":"yourgene-health-launches-lightbench-detect-for-fetal-fraction-enrichment","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/yourgene-health-launches-lightbench-detect-for-fetal-fraction-enrichment\/","title":{"rendered":"Yourgene Health Launches LightBench Detect for Fetal Fraction Enrichment"},"content":{"rendered":"<div>\n<ul class=\"bwlistdisc\">\n<li>\n<i>Offers flexibility in blood collection tube choice enabling cost-effective workflows in non-invasive prenatal testing<\/i>\n<\/li>\n<li>\n<i>Scalable and precise DNA size selection reduces no-call rates for improved patient outcomes<\/i>\n<\/li>\n<\/ul>\n<p>MANCHESTER, England&#8211;(BUSINESS WIRE)&#8211;Yourgene Health plc (\u201cYourgene\u201d, AIM: YGEN), a leading international molecular diagnostics group, announces today the launch of the LightBench<sup>\u00ae<\/sup> Detect, the latest addition to its Ranger<sup>\u00ae<\/sup> Technology instrumentation portfolio at the 26<sup>th<\/sup> International Conference on Prenatal Diagnosis and Therapy (ISPD). The Company has worked closely with its clinical laboratory partners to develop size selection methodologies optimised for improving the performance of liquid biopsy workflows, most notably non-invasive prenatal testing (NIPT). The LightBench Detect helps NIPT providers to reduce no-call rates by optimising average fetal fraction. Leveraging the unique size selection capabilities of Ranger Technology, the LightBench Detect also enables laboratories to consider the use of EDTA blood collection tubes (BCTs) instead of expensive specialised preservation blood collection tubes (BCT) in their workflows to help reduce overall costs.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20220620005175\/en\/1490945\/5\/yourgene-health-plc-logo-clear-bkground.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20220620005175\/en\/1490945\/21\/yourgene-health-plc-logo-clear-bkground.jpg\"><\/a><\/p>\n<p>\nThe LightBench Detect is a clinical-grade 3-in-1 electrophoretic instrument offering liquid biopsy and NIPT laboratories the ability to automate the process of DNA size selection and enrichment from samples stored for prolonged periods in EDTA BCTs. This core capability is complemented by the ability to perform fragment length analysis and fluorescence assays for quality control purposes. Cell free DNA (cfDNA) fragments of fetal origin are typically &lt;150bp in length, meaning size selection using the instrument can enrich for fetal fraction to reduce the number of no-call results or screening failures, helping improve overall patient outcomes. Use of the technology in NIPT offers scalable and precise DNA size selection and achieves &gt;97% reproducibility, ensuring consistent enrichment of the fetal fraction.\n<\/p>\n<p>\nThe use of this patent-pending, EDTA-enabling, technology will be presented by the Centre de recherche du CHU de Qu\u00e9bec-Universit\u00e9 Laval<sup>*<\/sup>. The group worked with Yourgene to compare fetal fraction in 61 samples collected from singleton pregnancies in Vancouver over a two-month period. Samples stored in the expensive BCTs had fetal fractions below 4% (a common pass\/fail threshold) 12% of the time, while samples stored in inexpensive EDTA tubes had zero cases of fetal fraction below 4% when paired with size selection. A low fetal fraction in NIPT will result in a no result and potentially a re-draw blood sample from the pregnant mother. They demonstrated that Ranger Technology offers an alternative solution to the use of expensive BCTs for stabilising NIPT samples. Yourgene has now made this capability accessible to the market via the LightBench Detect.\n<\/p>\n<p>\n<b>Lyn Rees, CEO of Yourgene Health, said:<\/b> \u201c<i>Every once in a while, a technology comes along that has the potential to disrupt standard clinical testing workflows and make real improvements, both to the test performance and the economics and efficiencies of a test. Working with Universit\u00e9 Laval has enabled us to deliver the LightBench Detect, which radically improves efficiencies by giving labs flexibility of choice around the blood collection tube they use without impacting performance. We are so excited to roll out this capability to other NIPT providers<\/i>.\u201d\n<\/p>\n<p>\nFor further information about the LightBench Detect, visit: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.yourgene-health.com%2Flightbench-detect&amp;esheet=52754947&amp;newsitemid=20220620005175&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.yourgene-health.com%2Flightbench-detect&amp;index=1&amp;md5=b7575d00431f4d88d9fb584ab9e1debf\" rel=\"nofollow noopener\" shape=\"rect\">https:\/\/www.yourgene-health.com\/lightbench-detect<\/a>\n<\/p>\n<p>\nYourgene will be attending the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.ispdhome.org%2FISPD2022&amp;esheet=52754947&amp;newsitemid=20220620005175&amp;lan=en-US&amp;anchor=ISPD&amp;index=2&amp;md5=a4f0f4f17e4fd5f4d3762a8acefa8bd3\" rel=\"nofollow noopener\" shape=\"rect\">ISPD<\/a> in Montreal, Canada from 19\u201323 June 2022. Visit booth #205 to learn more.\n<\/p>\n<p>\n<i><sup>*<\/sup><\/i><i>Daryabari et al., Improving fetal fraction in NIPT by size-selection of samples collected in EDTA gel tubes [Poster presented at <\/i><i>ISPD 2022 P-88]<\/i>\n<\/p>\n<p class=\"bwalignc\">\n<b>ENDS<\/b>\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\nZyme Communications<br \/>\n<br \/>Dr Michelle Ricketts<br \/>\n<br \/>Tel: +44 (0)7789 053 885<br \/>\n<br \/>Email: <a target=\"_blank\" href=\"m&#97;&#x69;&#x6c;&#x74;o&#58;&#109;&#x69;&#x63;h&#101;&#108;&#x6c;&#x65;&#46;r&#105;&#x63;&#x6b;&#x65;t&#116;&#x73;&#x40;&#x7a;y&#109;&#101;&#x63;&#x6f;m&#109;&#117;&#x6e;&#x69;ca&#116;&#x69;&#x6f;&#x6e;s&#46;&#99;&#x6f;&#x6d;\" rel=\"nofollow noopener\" shape=\"rect\">m&#105;&#x63;&#x68;e&#108;&#108;&#x65;&#x2e;r&#105;&#99;&#x6b;&#x65;t&#116;&#x73;&#x40;&#x7a;y&#109;&#x65;&#x63;o&#109;&#109;&#x75;&#x6e;i&#99;&#97;&#x74;&#x69;o&#110;&#x73;&#x2e;&#x63;o&#109;<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Offers flexibility in blood collection tube choice enabling cost-effective workflows in non-invasive prenatal testing Scalable and precise DNA size selection reduces no-call rates for improved patient outcomes MANCHESTER, England&#8211;(BUSINESS WIRE)&#8211;Yourgene Health plc (\u201cYourgene\u201d, AIM: YGEN), a leading international molecular diagnostics group, announces today the launch of the LightBench\u00ae Detect, the latest addition to its Ranger\u00ae &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/yourgene-health-launches-lightbench-detect-for-fetal-fraction-enrichment\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-45249","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Yourgene Health Launches LightBench Detect for Fetal Fraction Enrichment - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/yourgene-health-launches-lightbench-detect-for-fetal-fraction-enrichment\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Yourgene Health Launches LightBench Detect for Fetal Fraction Enrichment - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Offers flexibility in blood collection tube choice enabling cost-effective workflows in non-invasive prenatal testing Scalable and precise DNA size selection reduces no-call rates for improved patient outcomes MANCHESTER, England&#8211;(BUSINESS WIRE)&#8211;Yourgene Health plc (\u201cYourgene\u201d, AIM: YGEN), a leading international molecular diagnostics group, announces today the launch of the LightBench\u00ae Detect, the latest addition to its Ranger\u00ae ... 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