{"id":45537,"date":"2022-06-27T16:02:14","date_gmt":"2022-06-27T14:02:14","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/dxcover-publishes-research-highlighting-effective-early-detection-of-pancreatic-cancer-using-infrared-spectroscopy\/"},"modified":"2022-06-27T16:02:14","modified_gmt":"2022-06-27T14:02:14","slug":"dxcover-publishes-research-highlighting-effective-early-detection-of-pancreatic-cancer-using-infrared-spectroscopy","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/dxcover-publishes-research-highlighting-effective-early-detection-of-pancreatic-cancer-using-infrared-spectroscopy\/","title":{"rendered":"Dxcover Publishes Research Highlighting Effective Early Detection of Pancreatic Cancer Using Infrared Spectroscopy"},"content":{"rendered":"
\n

\nStudy published in Cancers demonstrates how simple, minimally invasive and accurate approaches can represent a powerful aid in earlier detection to improve patients\u2019 prognosis and quality of life<\/i>\n<\/p>\n

GLASGOW, Scotland–(BUSINESS WIRE)–Dxcover Limited<\/a>, a clinical stage diagnostics company developing spectroscopic liquid biopsy technology for early detection of multiple cancers, today announced findings from a new study that shows how Dxcover\u2019s infrared platform detects a solid and clear distinction between cancer and control samples when detecting early stage pancreatic cancer, suggesting a great potential for clinical implementation. The data has been published in Cancers<\/a><\/i>. <\/i>Pancreatic cancer is the seventh leading cause of cancer death and claims more than 460,000 lives per year. It is one of the hardest diseases to detect due to the lack of early symptomatic evidence and fast, simple, and non-invasive diagnostic tests. The carbohydrate antigen (CA) 19-9 test is the blood test used for pancreatic cancer\u2019s detection, but its levels can be raised in symptomatic patients with other non-malignant diseases, or with other tumors in the surrounding area.\n<\/p>\n

<\/a><\/p>\n

\nDxcover\u2019s proof-of-concept study, investigating the use of attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy on dried blood serum, focused on the discrimination of both cancer versus asymptomatic (healthy) control samples, and cancer versus symptomatic non-malignant control samples, as a novel liquid biopsy approach for pancreatic cancer diagnosis.\n<\/p>\n

\nMachine learning algorithms were applied, achieving results of 92% sensitivity and 88% specificity when discriminating between cancers (n = 100) and asymptomatic (healthy) controls (n = 100). An area under the curve (AUC) of 0.95 was obtained through receiver operating characteristic (ROC) analysis. In addition, the test identified cancerous patients among a challenging symptomatic cohort to an AUC of 0.83.\n<\/p>\n

\n\u201cTo our knowledge, this is the largest and most promising proof-of-concept study to date for clinical use of ATR-FTIR spectroscopy in the detection of early and advanced stages of pancreatic cancer. The use of our technology can save over $12 million in health care resources per 5000 cancers detected as well rapidly speed up the process for patients to get the required treatment sooner,\u201d said Dr. Matthew Baker, Chief Technology Officer and co-founder, Dxcover.\n<\/p>\n

\nAbout Dxcover Limited<\/b>\n<\/p>\n

\nDxcover is a clinical stage liquid biopsy company developing tests for the early detection of multiple cancers, when treatment has a better chance to impact outcomes. The company has pioneered the early detection and identification of cancer employing infrared spectroscopy of circulating pan-omic biomarkers. The company has generated compelling clinical data with high accuracy detection of Stage I and Stage II cancers. Dxcover is based in Scotland, United Kingdom and is establishing operations in the USA.\n<\/p>\n

\nFor further information go to https:\/\/www.dxcover.com\/science<\/a>\n<\/p>\n

Contacts<\/b> <\/p>\n

\nMedia:<\/b>
Tara Mulloy
\n
tmulloy@macdougall.bio<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Study published in Cancers demonstrates how simple, minimally invasive and accurate approaches can represent a powerful aid in earlier detection to improve patients\u2019 prognosis and quality of life GLASGOW, Scotland–(BUSINESS WIRE)–Dxcover Limited, a clinical stage diagnostics company developing spectroscopic liquid biopsy technology for early detection of multiple cancers, today announced findings from a new study … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-45537","6":"format-standard","7":"category-industry"},"yoast_head":"\nDxcover Publishes Research Highlighting Effective Early Detection of Pancreatic Cancer Using Infrared Spectroscopy - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/dxcover-publishes-research-highlighting-effective-early-detection-of-pancreatic-cancer-using-infrared-spectroscopy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dxcover Publishes Research Highlighting Effective Early Detection of Pancreatic Cancer Using Infrared Spectroscopy - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Study published in Cancers demonstrates how simple, minimally invasive and accurate approaches can represent a powerful aid in earlier detection to improve patients\u2019 prognosis and quality of life GLASGOW, Scotland–(BUSINESS WIRE)–Dxcover Limited, a clinical stage diagnostics company developing spectroscopic liquid biopsy technology for early detection of multiple cancers, today announced findings from a new study ... 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