{"id":45843,"date":"2022-07-06T10:01:55","date_gmt":"2022-07-06T08:01:55","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/gnubiotics-sciences-announces-funding-from-the-swiss-innovation-agency-to-accelerate-development-of-glycopeptide-mediated-immunotherapies-against-solid-tumors\/"},"modified":"2022-07-06T10:01:55","modified_gmt":"2022-07-06T08:01:55","slug":"gnubiotics-sciences-announces-funding-from-the-swiss-innovation-agency-to-accelerate-development-of-glycopeptide-mediated-immunotherapies-against-solid-tumors","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/gnubiotics-sciences-announces-funding-from-the-swiss-innovation-agency-to-accelerate-development-of-glycopeptide-mediated-immunotherapies-against-solid-tumors\/","title":{"rendered":"Gnubiotics Sciences Announces Funding from the Swiss Innovation Agency to Accelerate Development of Glycopeptide Mediated Immunotherapies against Solid Tumors"},"content":{"rendered":"<div>\n<p>LAUSANNE, Switzerland&#8211;(BUSINESS WIRE)&#8211;Gnubiotics Sciences, a biotech company pioneering the discovery and development of immunomodulatory glycopeptides, today announced that the Swiss Innovation Agency (Innosuisse) will support a research collaboration with the University Hospital Z\u00fcrich to accelerate the development of Gnubiotics\u2019 GLAAD technology in a range of solid tumors. The total project cost of CHF 1.4 million (USD 1.4 million) will be supported by the grant from Innosuisse as well as contributions from Gnubiotics.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20220706005036\/en\/1505088\/5\/Innosuisse_Gnubiotics.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20220706005036\/en\/1505088\/21\/Innosuisse_Gnubiotics.jpg\"><\/a><br \/><a href=\"https:\/\/mms.businesswire.com\/media\/20220706005036\/en\/1503716\/5\/thumbnail_image004-1.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20220706005036\/en\/1503716\/21\/thumbnail_image004-1.jpg\"><\/a><\/p>\n<p>\nAltered glycosylation of tumors is a signature of cancer development, making glycans an emerging target especially in immunotherapy resistant patient cohorts. The sponsored project will advance GNU201 and GNU101, as potential first-in-class immunotherapeutics that steer immune responses to control growth in solid tumors expressing altered O-glycan profiles thus responding to a critical need in non-responding patients. The multi-year project which will include dose-finding and key translational studies, forms a core part of a broader preclinical development plan that will support an Investigational New Drug Application (IND).\n<\/p>\n<p>\n\u201cThis support from Innosuisse and continued close collaboration with Prof. Michael Scharl`s group at the University Hospital Z\u00fcrich provide further validation of our GLAAD platform, which holds great therapeutic potential for anti-PD-1 resistant and other non-responsive patient cohorts\u201d stated Yemi Adesokan, Ph.D., Gnubiotics\u2019s Chief Executive Officer.\n<\/p>\n<p>\nGnubiotics presented compelling data recently at the 2022 American Society of Clinical Oncology (ASCO) annual meeting showing the effect of its glycopeptides platform in driving robust T-cell immune responses against anti-PD-1 resistant tumors in a colorectal cancer mouse model. Also announced recently, was a collaboration with the University of Pennsylvania to explore CAR-T therapy in combination with Gnubiotics\u2019 glycopeptides to enhance CAR-T efficacy in solid tumors.\n<\/p>\n<p>\nAbout GLAAD\n<\/p>\n<p>\nGlycopeptides are the foundation of Gnubiotics\u2019 GLAAD molecules. GLAAD relies on glycopeptides as providers of antigenicity and adjuvanticity to the immune system. Gnubiotics\u2019 GLAAD candidates are made of a range of glycans uniquely bound to peptides and can act directly on immune cells and modulate the microbiome. Combined, these modes of action influence the immune system responses which opens new ways to address areas where the immune system plays a role, including oncology, inflammatory and infectious diseases.\n<\/p>\n<p>\nAbout Innosuisse\n<\/p>\n<p>\nInnosuisse is the Swiss Innovation Agency. Its role is to promote science-based innovation in the interest of the economy and society in Switzerland. Innosuisse especially promotes the partnership between academia and the market with innovation projectslaying the groundwork for successful Swiss start-ups as well as innovative products and services.\n<\/p>\n<p>\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.innosuisse.ch&amp;esheet=52770138&amp;newsitemid=20220706005036&amp;lan=en-US&amp;anchor=www.innosuisse.ch&amp;index=1&amp;md5=8d92d8c7b04a44ac5c979c59fb335f94\" rel=\"nofollow noopener\" shape=\"rect\">www.innosuisse.ch<\/a>\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\nYemi Adesokan, Ph.D.<br \/>\n<br \/>Chief Executive Officer<br \/>\n<br \/>Email: <a target=\"_blank\" href=\"&#109;&#x61;i&#x6c;&#x74;&#111;&#x3a;i&#x6e;&#x66;&#111;&#x40;g&#x6e;&#x75;&#98;&#x69;o&#x74;&#x69;&#99;&#x73;&#46;&#x63;&#x6f;&#109;\" rel=\"nofollow noopener\" shape=\"rect\">&#105;&#x6e;f&#x6f;&#64;&#103;&#x6e;&#117;&#x62;i&#111;&#x74;&#105;&#x63;s&#x2e;&#x63;&#111;&#x6d;<\/a><br \/><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.gnubiotics.com&amp;esheet=52770138&amp;newsitemid=20220706005036&amp;lan=en-US&amp;anchor=www.gnubiotics.com&amp;index=2&amp;md5=3fd5111f70f983a2f01be7e1b3313e49\" rel=\"nofollow noopener\" shape=\"rect\">www.gnubiotics.com<\/a><br \/><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fgnubiotics%2F&amp;esheet=52770138&amp;newsitemid=20220706005036&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fgnubiotics%2F&amp;index=3&amp;md5=927ff510eb542ce6174e0caa380d7730\" rel=\"nofollow noopener\" shape=\"rect\">https:\/\/www.linkedin.com\/company\/gnubiotics\/<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>LAUSANNE, Switzerland&#8211;(BUSINESS WIRE)&#8211;Gnubiotics Sciences, a biotech company pioneering the discovery and development of immunomodulatory glycopeptides, today announced that the Swiss Innovation Agency (Innosuisse) will support a research collaboration with the University Hospital Z\u00fcrich to accelerate the development of Gnubiotics\u2019 GLAAD technology in a range of solid tumors. The total project cost of CHF 1.4 million &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/gnubiotics-sciences-announces-funding-from-the-swiss-innovation-agency-to-accelerate-development-of-glycopeptide-mediated-immunotherapies-against-solid-tumors\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["entry","post","publish","author-business","post-45843","format-standard","category-industry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Gnubiotics Sciences Announces Funding from the Swiss Innovation Agency to Accelerate Development of Glycopeptide Mediated Immunotherapies against Solid Tumors - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/gnubiotics-sciences-announces-funding-from-the-swiss-innovation-agency-to-accelerate-development-of-glycopeptide-mediated-immunotherapies-against-solid-tumors\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gnubiotics Sciences Announces Funding from the Swiss Innovation Agency to Accelerate Development of Glycopeptide Mediated Immunotherapies against Solid Tumors - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"LAUSANNE, Switzerland&#8211;(BUSINESS WIRE)&#8211;Gnubiotics Sciences, a biotech company pioneering the discovery and development of immunomodulatory glycopeptides, today announced that the Swiss Innovation Agency (Innosuisse) will support a research collaboration with the University Hospital Z\u00fcrich to accelerate the development of Gnubiotics\u2019 GLAAD technology in a range of solid tumors. The total project cost of CHF 1.4 million ... 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