{"id":46512,"date":"2022-07-25T14:01:46","date_gmt":"2022-07-25T12:01:46","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/iama-therapeutics-announces-initiation-of-preclinical-development-studies-in-drug-resistant-epilepsy-under-a-service-agreement-with-psychogenics\/"},"modified":"2022-07-25T14:01:46","modified_gmt":"2022-07-25T12:01:46","slug":"iama-therapeutics-announces-initiation-of-preclinical-development-studies-in-drug-resistant-epilepsy-under-a-service-agreement-with-psychogenics","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/iama-therapeutics-announces-initiation-of-preclinical-development-studies-in-drug-resistant-epilepsy-under-a-service-agreement-with-psychogenics\/","title":{"rendered":"IAMA Therapeutics Announces Initiation of Preclinical Development Studies in Drug-resistant Epilepsy Under a Service Agreement with Psychogenics"},"content":{"rendered":"
\n

GENOA, Italy–(BUSINESS WIRE)–#autism<\/a>–IAMA Therapeutics, a preclinical-stage pharmaceutical company focused on the discovery, development, and commercialization of novel medicines to make a difference in the lives of individuals suffering from brain disorders, and PsychoGenics Inc., a leader in AI-enabled phenotypic drug discovery and preclinical CRO services, today announced that the companies have entered into a service agreement to identify the efficacy of novel drug candidates in drug-resistant epilepsy.\n<\/p>\n

<\/a><\/p>\n

\nUnder the terms of the agreement, PsychoGenics will evaluate the preclinical anti-seizure efficacy of first-in-class selective-NKCC1 inhibitors, which aims to reduce intracellular chloride concentration and restore the physiological hyperpolarizing and inhibitory GABAergic transmission in an animal model of refractory epilepsy.\n<\/p>\n

\n“PsychoGenics is a leader in preclinical behavioral neurobiology with a successful track record of anti-epilepsy drug testing through translational EEG approaches, including electrographic and behavioral identification of seizure,” said Andrea P. Malizia, Ph.D., MBA, Chief Executive Officer of IAMA Therapeutics. “We look forward to leveraging our collective expertise in neuroscience drug development to identify and evaluate the anti-seizure efficacy of new drug candidates, to enhance further and complement our pipeline of differentiated therapeutic opportunities for epilepsy, neurodevelopmental and cognitive disorders.”\n<\/p>\n

\n\u201cWe are excited to embark of these studies with IAMA Therapeutics\u201d said Stephen Morairty, Ph.D., Vice President of Translational Neuroscience at PsychoGenics. \u201cUsing our pre-clinical MTLE model, will carefully evaluate the efficacy of these first-in-class selective-NKCC1 inhibitors.\u201d\n<\/p>\n

\nAbout IAMA Therapeutics<\/strong>\n<\/p>\n

\nIAMA Therapeutics is a preclinical-stage pharmaceutical company focused on discovering, developing, and commercializing novel medicines to make a difference in the lives of children and adults suffering from epilepsy, neurodevelopmental and cognitive disorders. IAMA Therapeutics couples emerging advances in drug discovery and neurobiology to build a leading, next-generation neuroscience pipeline to selectively inhibit the sodium-potassium chloride cotransporter and other therapeutic targets relevant to brain disorders characterized by neuronal imbalance.\n<\/p>\n

\nThe company’s preclinical pipeline consists of the lead candidate IAMA-6 for the treatment of idiopathic autism, IAMA-097 for the treatment of secondary and rare forms of autism, and other compounds for treating refractory epilepsy and other brain disorders.\n<\/p>\n

\nFor more information, please visit https:\/\/iamatherapeutics.com\/<\/a>\n<\/p>\n

\nAbout PsychoGenics Inc.<\/strong>\n<\/p>\n

\nPsychoGenics is a leader in vivo phenotypic drug discovery. The company applies its proprietary technology platforms in partnership with pharmaceutical and biotechnology companies to discover the next generation of drugs for neuropsychiatric disorders. PsychoGenics’ capabilities include standard behavioral testing, electrophysiology, translational EEG, molecular biology, and state-of-the-art microdialysis. In addition, the company offers a variety of in-licensed transgenic mouse models that support research in areas such as Huntington’s disease, Autism spectrum disorders, psychosis\/schizophrenia, Alzheimer’s disease, Parkinson’s disease, sleep, and Spinal Muscular Atrophy (SMA), muscular dystrophy and other muscle disorders.\n<\/p>\n

\nFor more information on PsychoGenics Inc., visit www.psychogenics.com<\/a>.\n<\/p>\n

Contacts<\/b> <\/p>\n

\nIAMA Therapeutics Contact
\n
Andrea P. Malizia, Ph.D., MBA
\n
CEO
\n
+39 3452160044
\n
media@iamatherapeutics.com<\/a>\n<\/p>\n

\nPsychoGenics Inc. Contact
\n
Emer Leahy, Ph.D.
\n
President and CEO
\n
+1 914-406-8008
\n
emer.leahy@psychogenics.com<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

GENOA, Italy–(BUSINESS WIRE)–#autism–IAMA Therapeutics, a preclinical-stage pharmaceutical company focused on the discovery, development, and commercialization of novel medicines to make a difference in the lives of individuals suffering from brain disorders, and PsychoGenics Inc., a leader in AI-enabled phenotypic drug discovery and preclinical CRO services, today announced that the companies have entered into a service … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-46512","6":"format-standard","7":"category-industry"},"yoast_head":"\nIAMA Therapeutics Announces Initiation of Preclinical Development Studies in Drug-resistant Epilepsy Under a Service Agreement with Psychogenics - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/iama-therapeutics-announces-initiation-of-preclinical-development-studies-in-drug-resistant-epilepsy-under-a-service-agreement-with-psychogenics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IAMA Therapeutics Announces Initiation of Preclinical Development Studies in Drug-resistant Epilepsy Under a Service Agreement with Psychogenics - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"GENOA, Italy–(BUSINESS WIRE)–#autism–IAMA Therapeutics, a preclinical-stage pharmaceutical company focused on the discovery, development, and commercialization of novel medicines to make a difference in the lives of individuals suffering from brain disorders, and PsychoGenics Inc., a leader in AI-enabled phenotypic drug discovery and preclinical CRO services, today announced that the companies have entered into a service ... 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