{"id":46738,"date":"2022-07-29T15:01:55","date_gmt":"2022-07-29T13:01:55","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/amylyx-pharmaceuticals-announces-albrioza-is-now-available-in-canada-for-the-treatment-of-als\/"},"modified":"2022-07-29T15:01:55","modified_gmt":"2022-07-29T13:01:55","slug":"amylyx-pharmaceuticals-announces-albrioza-is-now-available-in-canada-for-the-treatment-of-als","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/amylyx-pharmaceuticals-announces-albrioza-is-now-available-in-canada-for-the-treatment-of-als\/","title":{"rendered":"Amylyx Pharmaceuticals Announces ALBRIOZA\u2122 is Now Available in Canada for the Treatment of ALS"},"content":{"rendered":"<div>\n<p>CAMBRIDGE, Mass.&#8211;(BUSINESS WIRE)&#8211;Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) (\u201cAmylyx\u201d or the \u201cCompany\u201d) today announced that ALBRIOZA\u2122 (sodium phenylbutyrate and ursodoxicoltaurine) is now commercially available in Canada for people living with amyotrophic lateral sclerosis (ALS). ALBRIOZA (also known as AMX0035) is an oral fixed-dose combination therapy that may reduce neuronal cell death as a stand-alone therapy or when added to existing treatments. In a clinical trial, ALBRIOZA significantly slowed disease progression and loss of functional decline in people living with ALS.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20220728006051\/en\/802420\/5\/13268_Amylyx_logo_notagline-Color.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20220728006051\/en\/802420\/21\/13268_Amylyx_logo_notagline-Color.jpg\"><\/a><\/p>\n<p>\n\u201cWe have remained steadfast in our commitment to ensure ALBRIOZA would be available in Canada as quickly as possible following Health Canada\u2019s decision to approve ALBRIOZA, with conditions, in June,\u201d said Margaret Olinger, Chief Commercial Officer at Amylyx. \u201cWe are pleased that starting this week, we are ready to fill prescriptions for ALBRIOZA.\u201d\n<\/p>\n<p>\nAmylyx filed reimbursement submissions to the Canadian Agency for Drugs and Technologies (CADTH) and Institut national d\u2019excellence en sant\u00e9 et en services sociaux (INESSS) in Quebec as part of an aligned Health Technology Assessments (HTA) review with Health Canada in parallel with the regulatory process to reduce the timelines required for patient access. The Company is continuing to work with the pan-Canadian Pharmaceutical Alliance, Federal, Provincial, and Territorial public drug plans, and private insurers to expeditiously achieve listing and reimbursement, so that eligible Canadians living with ALS can have access to ALBRIOZA as quickly and efficiently as possible.\n<\/p>\n<p>\n\u201cIn Canada, prescription drugs undergo a thorough and often long review and approval process across regulatory, HTA, pricing negotiations, and formulary listing with public drug plans. In addition, private insurers have their own review and listing processes,\u201d said Chris Aiello, General Manager and Head of Canada at Amylyx. \u201cWe continue to work diligently to navigate reimbursement processes to pursue broad and equitable access to ALBRIOZA across all provinces in Canada.\u201d\n<\/p>\n<p>\n\u201cMarket availability is an important milestone in the available treatment options for people living with ALS,\u201d said Tammy Moore, CEO of the ALS Society of Canada. \u201cAs we look forward, we do not want to see coverage decisions become a barrier to access, and we urge the decision-makers throughout the drug access and reimbursement process to work expeditiously to provide equitable access for all eligible Canadians living with ALS who are in desperate need.\u201d\n<\/p>\n<p>\nAs part of Amylyx\u2019 continued commitment to the ALS community, through the Amylyx Care Team (ACT) Support Program, Amylyx provides insurance navigation, treatment coordination and educational support for people living with ALS who have been prescribed ALBRIOZA in Canada and their caregivers. Eligibility and enrollment into the ACT Support Program can be discussed with prescribing health care professionals.\n<\/p>\n<p>\nFor product information, please visit <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.amylyx.ca%2Fproduct&amp;esheet=52795350&amp;newsitemid=20220728006051&amp;lan=en-US&amp;anchor=www.amylyx.ca%2Fproduct&amp;index=1&amp;md5=325de7cdc18d670629a0164bfc905551\" rel=\"nofollow noopener\" shape=\"rect\">www.amylyx.ca\/product<\/a>.\n<\/p>\n<p>\n<b>About ALBRIOZA\u2122<\/b>\n<\/p>\n<p>\nALBRIOZA\u2122 (sodium phenylbutyrate and taurursodiol) is an oral fixed-dose medication approved with conditions to treat amyotrophic lateral sclerosis (ALS) in Canada and with marketing applications pending in the United States and European Union. The combination of sodium phenylbutyrate and taurursodiol may reduce neuronal cell death, hypothesized to occur by simultaneously mitigating endoplasmic reticulum (ER) stress and mitochondrial dysfunction. ALBRIOZA is also being explored for the potential treatment of other neurodegenerative diseases.\n<\/p>\n<p>\n<b>About Amylyx Pharmaceuticals<\/b>\n<\/p>\n<p>\nAmylyx Pharmaceuticals, Inc. is committed to supporting and creating more moments for the neurodegenerative community through the discovery and development of innovative new treatments. Amylyx is headquartered in Cambridge, Massachusetts and has operations in Canada and EMEA. For more information, visit <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Famylyx.com%2F&amp;esheet=52795350&amp;newsitemid=20220728006051&amp;lan=en-US&amp;anchor=amylyx.com&amp;index=2&amp;md5=2cf49cee0b134bddd1f0d3cfd06acd3a\" rel=\"nofollow noopener\" shape=\"rect\">amylyx.com<\/a> and follow us on <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Famylyx&amp;esheet=52795350&amp;newsitemid=20220728006051&amp;lan=en-US&amp;anchor=LinkedIn&amp;index=3&amp;md5=2840936ca3534a374c714224169ccbe0\" rel=\"nofollow noopener\" shape=\"rect\">LinkedIn<\/a> and <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ftwitter.com%2FAmylyxPharma&amp;esheet=52795350&amp;newsitemid=20220728006051&amp;lan=en-US&amp;anchor=Twitter&amp;index=4&amp;md5=0593515165f4cd826a2aeaa7d2e2f23a\" rel=\"nofollow noopener\" shape=\"rect\">Twitter<\/a>. For investors please visit <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Finvestors.amylyx.com%2F&amp;esheet=52795350&amp;newsitemid=20220728006051&amp;lan=en-US&amp;anchor=investors.amylyx.com&amp;index=5&amp;md5=2f9f066dfda4c03c1695a6087b3ee824\" rel=\"nofollow noopener\" shape=\"rect\">investors.amylyx.com<\/a>.\n<\/p>\n<p>\n<b>Forward-Looking Statements<\/b>\n<\/p>\n<p>\nStatements contained in this press release regarding matters that are not historical facts are \u201cforward-looking statements\u201d within the meaning the of Private Securities Litigation Reform Act of 1995, as amended. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Such statements include, but are not limited to, statements regarding the potential regulatory approval of AMX0035 and the potential of AMX0035 or other future therapeutic candidates as a treatment for ALS and other neurodegenerative diseases. Any forward-looking statements in this statement are based on management\u2019s current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. Risks that contribute to the uncertain nature of the forward-looking statements include: the success, cost, and timing of Amylyx\u2019 program development activities, Amylyx\u2019 ability to execute on its strategy, regulatory developments, expectations regarding the timing of regulatory review of AMX0035, Amylyx\u2019 ability to fund operations, and the impact that the ongoing COVID-19 pandemic will have on Amylyx\u2019 operations, as well as those risks and uncertainties set forth in Amylyx\u2019 United States Securities and Exchange Commission (SEC) filings, including Amylyx\u2019 Annual Report on Form 10-K for the year ended December 31, 2021, and subsequent filings with the SEC. All forward-looking statements contained in this press release speak only as of the date on which they were made. Amylyx undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\n<b>Media<\/b><br \/>Becky Gohsler<br \/>\n<br \/>Finn Partners<br \/>\n<br \/>(646) 307-6307<br \/>\n<br \/><a target=\"_blank\" href=\"&#109;&#x61;i&#x6c;&#x74;&#111;&#x3a;a&#x6d;&#x79;&#108;&#x79;x&#x6d;&#x65;&#100;&#x69;a&#x74;&#x65;&#97;&#x6d;&#64;&#x61;&#x6d;&#121;&#x6c;y&#x78;&#x2e;&#99;&#x6f;m\" rel=\"nofollow noopener\" shape=\"rect\">&#x61;&#x6d;&#x79;&#108;&#121;xm&#x65;&#x64;&#x69;&#x61;&#116;&#101;am&#x40;&#x61;&#x6d;&#121;&#108;&#121;x&#46;&#x63;&#x6f;&#x6d;<\/a><\/p>\n<p><b>Investors<\/b><br \/>Lindsey Allen<br \/>\n<br \/>Amylyx Pharmaceuticals, Inc.<br \/>\n<br \/>(857) 320-6244<br \/>\n<br \/><a target=\"_blank\" href=\"&#109;&#x61;i&#x6c;&#x74;&#111;&#x3a;I&#x6e;&#x76;&#101;&#x73;t&#x6f;&#x72;&#115;&#x40;a&#x6d;&#x79;&#108;&#x79;x&#x2e;&#x63;&#111;&#x6d;\" rel=\"nofollow noopener\" shape=\"rect\">&#x49;n&#x76;e&#x73;&#116;&#x6f;&#114;s&#x40;a&#x6d;&#121;&#x6c;&#121;&#x78;&#46;c&#x6f;m<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>CAMBRIDGE, Mass.&#8211;(BUSINESS WIRE)&#8211;Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) (\u201cAmylyx\u201d or the \u201cCompany\u201d) today announced that ALBRIOZA\u2122 (sodium phenylbutyrate and ursodoxicoltaurine) is now commercially available in Canada for people living with amyotrophic lateral sclerosis (ALS). ALBRIOZA (also known as AMX0035) is an oral fixed-dose combination therapy that may reduce neuronal cell death as a stand-alone therapy or &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/amylyx-pharmaceuticals-announces-albrioza-is-now-available-in-canada-for-the-treatment-of-als\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-46738","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Amylyx Pharmaceuticals Announces ALBRIOZA\u2122 is Now Available in Canada for the Treatment of ALS - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/amylyx-pharmaceuticals-announces-albrioza-is-now-available-in-canada-for-the-treatment-of-als\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Amylyx Pharmaceuticals Announces ALBRIOZA\u2122 is Now Available in Canada for the Treatment of ALS - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"CAMBRIDGE, Mass.&#8211;(BUSINESS WIRE)&#8211;Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) (\u201cAmylyx\u201d or the \u201cCompany\u201d) today announced that ALBRIOZA\u2122 (sodium phenylbutyrate and ursodoxicoltaurine) is now commercially available in Canada for people living with amyotrophic lateral sclerosis (ALS). ALBRIOZA (also known as AMX0035) is an oral fixed-dose combination therapy that may reduce neuronal cell death as a stand-alone therapy or ... 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(NASDAQ: AMLX) (\u201cAmylyx\u201d or the \u201cCompany\u201d) today announced that ALBRIOZA\u2122 (sodium phenylbutyrate and ursodoxicoltaurine) is now commercially available in Canada for people living with amyotrophic lateral sclerosis (ALS). ALBRIOZA (also known as AMX0035) is an oral fixed-dose combination therapy that may reduce neuronal cell death as a stand-alone therapy or ... 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