{"id":46785,"date":"2022-08-01T14:01:50","date_gmt":"2022-08-01T12:01:50","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/new-cryo-plasma-focused-ion-beam-to-streamline-cellular-cryo-electron-tomography-research\/"},"modified":"2022-08-01T14:01:50","modified_gmt":"2022-08-01T12:01:50","slug":"new-cryo-plasma-focused-ion-beam-to-streamline-cellular-cryo-electron-tomography-research","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/new-cryo-plasma-focused-ion-beam-to-streamline-cellular-cryo-electron-tomography-research\/","title":{"rendered":"New Cryo-Plasma Focused Ion Beam to Streamline Cellular Cryo-Electron Tomography Research"},"content":{"rendered":"<div>\n<p class=\"bwalignc\">\n<i>Thermo Scientific Arctis Cryo-Plasma FIB enables speed and consistency of cellular cryo-electron tomography<\/i>\n<\/p>\n<p>HILLSBORO, Ore.&#8211;(BUSINESS WIRE)&#8211;Thermo Fisher Scientific Inc., the world leader in serving science, today unveiled the Thermo Scientific Arctis Cryo-Plasma Focused Ion Beam (Cryo-PFIB), a new connected and automated microscope designed to advance the pace of cryo-electron tomography (cryo-ET) research.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20220801005011\/en\/1525388\/5\/Arctis-Press-Release-1200x630-2.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20220801005011\/en\/1525388\/21\/Arctis-Press-Release-1200x630-2.jpg\"><\/a><br \/><a href=\"https:\/\/mms.businesswire.com\/media\/20220801005011\/en\/1387941\/5\/Thermo_Fisher_Scientific.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20220801005011\/en\/1387941\/21\/Thermo_Fisher_Scientific.jpg\"><\/a><\/p>\n<p>\nCryo-ET makes it possible to study how proteins and other molecules operate together in a cellular context, at resolutions unsurpassed by other microscopy techniques, and has enormous potential for cell biology research, including the study of infectious disease, neurodegenerative disease, and other globally impactful structural biology applications. However, the process of preparing optimal samples for cryo-ET is still time-consuming and complex.\n<\/p>\n<p>\nThe Arctis Cryo-PFIB helps users address these challenges with advanced automation and new connectivity capabilities within the workflow, significantly increasing throughput compared to other commercially available solutions for fast, reproducible production of samples for cryo-ET.\n<\/p>\n<p>\n\u201cOur goal is to provide an end-to-end cryo-ET workflow for new and experienced users,\u201d said Trisha Rice, vice president and general manager of life sciences at Thermo Fisher. \u201cBy expanding our automation capabilities to our cryo-PFIB portfolio, we can pave the way for cryo-ET to become a frontier technique for cell biology.\u201d\n<\/p>\n<p>\nThe system is designed to provide high-quality samples with consistent thickness while minimizing sample contamination risks. Users will benefit from integrated correlative microscopy, dedicated Plasma FIB technology, advanced automation and new connectivity capabilities, including simplified sample loading and transfer. Highlights include:\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\n<b>Integrated correlative light and electron microscopy (CLEM) <\/b>for quick targeting of the area of biological interest.\n<\/li>\n<li>\n<b>Plasma FIB technology <\/b>for rapid removal of large sample volumes and quick access to areas of biological interest.\n<\/li>\n<li>\n<b>Automation capabilities<\/b> to simplify sample preparation and enable remote operation, allowing for long automated runs, reproducible results and higher throughput compared to current gallium-based cryo-FIB solutions.\n<\/li>\n<li>\n<b>Connectivity in the workflow<\/b> for simplifying the transfer of samples to the Thermo Scientific Krios or Glacios Cryo-TEMs<b>.<\/b> The Arctis Cryo-PFIB comes with Thermo Fisher\u2019s industry-leading Autoloader which robotically loads cassettes with up to 12 grids. New dedicated TomoGrids are designed to achieve optimal alignment of the lamella to the TEM tilt axis.\n<\/li>\n<\/ul>\n<p>\n\u201cThrough a strategic effort with Thermo Fisher Scientific on the build of this innovative cryo-PFIB, we hope to increase\u2014by a factor of ten\u2014the number of biological specimens that can be prepared for analysis by structural biology, and pioneer large volume cryo-ET,\u201d said Jim Naismith, director of The Rosalind Franklin Institute and collaborator in the development of the Thermo Scientific Arctis Cryo-PFIB.\n<\/p>\n<p>\nThermo Fisher Scientific and The Rosalind Franklin Institute <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fter.li%2Fmgoofb&amp;esheet=52792876&amp;newsitemid=20220801005011&amp;lan=en-US&amp;anchor=began+working+together+in+2019&amp;index=1&amp;md5=9b1b33393d69cca2b883948861712043\" rel=\"nofollow noopener\" shape=\"rect\">began working together in 2019<\/a>, using existing technology to understand and determine what\u2019s next for cryo-EM, and where innovation would be needed to create the next generation of instrumentation.\n<\/p>\n<p>\n\u201cOur joint ambition to drive scientific and technological breakthroughs, and our goal of increasing access to cryo-EM to as many scientists as possible, make The Rosalind Franklin Institute and Thermo Fisher Scientific ideal collaborators,\u201d added Naismith. \u201cWe will continue to work together to democratize the technique and create incremental yet impactful improvements to the workflow.\u201d\n<\/p>\n<p>\nLearn more about the Thermo Scientific Arctis Cryo-PFIB: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fter.li%2Fd2gsjm&amp;esheet=52792876&amp;newsitemid=20220801005011&amp;lan=en-US&amp;anchor=https%3A%2F%2Fter.li%2Fd2gsjm&amp;index=2&amp;md5=7a2a8de2aa6320f58f75f07f792f1fb4\" rel=\"nofollow noopener\" shape=\"rect\">https:\/\/ter.li\/d2gsjm<\/a>\n<\/p>\n<p>\nRegister for the product launch webinar on September 21: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fter.li%2Fydkoho&amp;esheet=52792876&amp;newsitemid=20220801005011&amp;lan=en-US&amp;anchor=https%3A%2F%2Fter.li%2Fydkoho&amp;index=3&amp;md5=88920877aad114ca03c7979066e529cc\" rel=\"nofollow noopener\" shape=\"rect\">https:\/\/ter.li\/ydkoho<\/a>\n<\/p>\n<p>\n<b>About Thermo Fisher Scientific<\/b>\n<\/p>\n<p>\nThermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of approximately $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, increasing productivity in their laboratories, improving patient health through diagnostics or the development and manufacture of life-changing therapies, we are here to support them. Our global team delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD. For more information, please visit <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.thermofisher.com&amp;esheet=52792876&amp;newsitemid=20220801005011&amp;lan=en-US&amp;anchor=www.thermofisher.com&amp;index=4&amp;md5=28f4af8f03634c2b303e1ec18779d632\" rel=\"nofollow noopener\" shape=\"rect\">www.thermofisher.com<\/a>.\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\nMedia Contact Information:<br \/>\n<br \/>Brianna Radicioni<br \/>\n<br \/>Thermo Fisher Scientific<br \/>\n<br \/>+1 617-390-3924<br \/>\n<br \/><a target=\"_blank\" href=\"&#109;&#x61;&#x69;l&#116;&#x6f;:&#98;&#x72;i&#97;&#x6e;n&#97;&#x2e;&#x72;&#97;&#x64;&#x69;c&#105;&#x6f;n&#105;&#x40;t&#104;&#x65;&#x72;&#109;&#x6f;&#x66;i&#115;&#x68;e&#114;&#x2e;c&#111;&#x6d;\" rel=\"nofollow noopener\" shape=\"rect\">&#x62;&#x72;&#x69;&#x61;&#x6e;&#x6e;&#x61;&#x2e;&#114;&#97;&#100;&#105;&#99;&#105;&#111;ni&#64;t&#x68;&#x65;&#x72;&#x6d;&#x6f;&#x66;&#x69;&#x73;&#x68;&#101;&#114;&#46;&#99;&#111;&#109;<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Thermo Scientific Arctis Cryo-Plasma FIB enables speed and consistency of cellular cryo-electron tomography HILLSBORO, Ore.&#8211;(BUSINESS WIRE)&#8211;Thermo Fisher Scientific Inc., the world leader in serving science, today unveiled the Thermo Scientific Arctis Cryo-Plasma Focused Ion Beam (Cryo-PFIB), a new connected and automated microscope designed to advance the pace of cryo-electron tomography (cryo-ET) research. Cryo-ET makes it &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/new-cryo-plasma-focused-ion-beam-to-streamline-cellular-cryo-electron-tomography-research\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-46785","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>New Cryo-Plasma Focused Ion Beam to Streamline Cellular Cryo-Electron Tomography Research - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/new-cryo-plasma-focused-ion-beam-to-streamline-cellular-cryo-electron-tomography-research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Cryo-Plasma Focused Ion Beam to Streamline Cellular Cryo-Electron Tomography Research - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Thermo Scientific Arctis Cryo-Plasma FIB enables speed and consistency of cellular cryo-electron tomography HILLSBORO, Ore.&#8211;(BUSINESS WIRE)&#8211;Thermo Fisher Scientific Inc., the world leader in serving science, today unveiled the Thermo Scientific Arctis Cryo-Plasma Focused Ion Beam (Cryo-PFIB), a new connected and automated microscope designed to advance the pace of cryo-electron tomography (cryo-ET) research. 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