{"id":46929,"date":"2022-08-04T13:01:46","date_gmt":"2022-08-04T11:01:46","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/"},"modified":"2022-08-04T13:01:46","modified_gmt":"2022-08-04T11:01:46","slug":"ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/","title":{"rendered":"Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand"},"content":{"rendered":"<div>\n<p class=\"bwalignc\">\n<i>\u2013 LINZESS (Iinaclotide) EUTRx prescription demand growth in Q2 2022 increased 9% year-over-year \u2013<\/i>\n<\/p>\n<p class=\"bwalignc\">\n<i>\u2013 GAAP net income of $37 million and adjusted EBITDA of $56 million; <\/i><i>ended Q2 2022 with $504 million in cash and cash equivalents \u2013<\/i>\n<\/p>\n<p class=\"bwalignc\">\n<i>\u2013 Completes Board of Directors authorized share repurchase program; repays remaining principal amount of the 2022 Convertible Notes in cash \u2013<\/i>\n<\/p>\n<p class=\"bwalignc\">\n<i>\u2013 Reiterates 2022 guidance of U.S. LINZESS net sales growth of low single digits %, total Ironwood revenue of $420 to $430 million and adjusted EBITDA of &gt;$250 million \u2013<\/i>\n<\/p>\n<p>BOSTON&#8211;(BUSINESS WIRE)&#8211;<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.ironwoodpharma.com%2F&amp;esheet=52800638&amp;newsitemid=20220804005059&amp;lan=en-US&amp;anchor=Ironwood+Pharmaceuticals%2C+Inc.&amp;index=1&amp;md5=7860bca328f114ad442c4f5b03d1f6d7\" rel=\"nofollow noopener\" shape=\"rect\">Ironwood Pharmaceuticals, Inc.<\/a> (Nasdaq: IRWD), a GI-focused healthcare company, today reported its second quarter 2022 results and recent business performance.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20220804005059\/en\/618520\/4\/IRWD_Logo_Color_Vertical_RD_RGB.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20220804005059\/en\/618520\/21\/IRWD_Logo_Color_Vertical_RD_RGB.jpg\"><\/a><\/p>\n<p>\n\u201cWe made progress towards our goal of becoming the leading GI healthcare company in the U.S., as the positive momentum across our business continued in the second quarter,\u201d said Tom McCourt, chief executive officer of Ironwood. \u201cWe are pleased by the year-over-year double-digit LINZESS prescription demand growth in the first half of 2022, and we believe there is still significant opportunity to reach appropriate new patients and drive additional growth for the brand. In addition to the commercial success of LINZESS, we continue to make progress with our ongoing clinical trials. We now expect our Phase 3 pediatric study of linaclotide in 6 to 17 year-olds with functional constipation to readout in the third quarter of this year and remain on track with the previously shared data readout timing for IW-3300 and CNP-104. We believe our capabilities in GI, strong balance sheet and disciplined capital allocation continue to position our company for growth moving forward.\u201d\n<\/p>\n<table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwpadl0\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>Second Quarter 2022 Financial Highlights<sup>1<\/sup><\/b>\n<\/p>\n<p class=\"bwcellpmargin\">\n<i>(in thousands, except for per share amounts)<\/i>\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc bwsinglebottom\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>2Q 2022<\/b>\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc bwsinglebottom\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>2Q 2021<\/b>\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTotal revenues\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n$97,231\n<\/p>\n<\/td>\n<td class=\"bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n$104,031\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTotal operating expenses\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n41,576\n<\/p>\n<\/td>\n<td class=\"bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n38,933\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nGAAP net income\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n37,080\n<\/p>\n<\/td>\n<td class=\"bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n391,303\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nGAAP net income per share \u2013 basic\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n0.24\n<\/p>\n<\/td>\n<td class=\"bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n2.42\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nGAAP net income per share \u2013diluted\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n0.21\n<\/p>\n<\/td>\n<td class=\"bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n2.39\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nAdjusted EBITDA\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n56,015\n<\/p>\n<\/td>\n<td class=\"bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n65,212\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nNon-GAAP net income\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n37,761\n<\/p>\n<\/td>\n<td class=\"bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n56,387\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nNon-GAAP net income per share \u2013 basic\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n0.24\n<\/p>\n<\/td>\n<td class=\"bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n0.35\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nNon-GAAP net income per share \u2013 diluted\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n0.21\n<\/p>\n<\/td>\n<td class=\"bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignr\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignr\">\n0.34\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<ol class=\"bwlistdecimal\">\n<li>\nRefer to the Reconciliation of GAAP Results to Non-GAAP Financial Measures table and to the Reconciliation of GAAP Net Income to Adjusted EBITDA table at the end of this press release. Refer to Non-GAAP Financial Measures for additional information.\n<\/li>\n<\/ol>\n<p>\n<b>Second Quarter 2022 Corporate Highlights<\/b>\n<\/p>\n<p>\n<b>U.S. LINZESS<\/b>\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\n<span class=\"bwuline\">Prescription Demand<\/span>: Total LINZESS prescription demand in the second quarter of 2022 was 43 million LINZESS capsules, a 9% increase compared to the second quarter of 2021, per IQVIA.\n<\/li>\n<li>\n<span class=\"bwuline\">U.S. Brand Collaboration<\/span>: LINZESS U.S. net sales are provided to Ironwood by its U.S. partner, AbbVie Inc. (\u201cAbbVie\u201d). LINZESS U.S. net sales were $248.4 million in the second quarter of 2022, a 4% decrease compared to $259.3 million in the second quarter of 2021.<\/p>\n<ul class=\"bwlistsquare\">\n<li>\nIronwood and AbbVie share equally in U.S. brand collaboration profits. See the LINZESS U.S. Commercial Collaboration table at the end of the press release.\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p class=\"bwmarginl1\">\n\u2013 LINZESS commercial margin was 69% in the second quarter of 2022, compared to 72% in the second quarter of 2021. See the U.S. LINZESS Full Brand Collaboration table below and at the end of this press release.\n<\/p>\n<p class=\"bwmarginl1\">\n\u2013 Net profit for the LINZESS U.S. brand collaboration, net of commercial and research and development (\u201cR&amp;D\u201d) expenses, was $163.8 million in the second quarter of 2022, compared to $176.6 million in the second quarter of 2021. See U.S. LINZESS Full Brand Collaboration table below and at the end of this press release.\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\n<span class=\"bwuline\">Collaboration Revenue to Ironwood<\/span>: Ironwood recorded $94.5 million in collaboration revenue in the second quarter of 2022 related to sales of LINZESS in the U.S., a 6% decrease compared to $100.3 million for the second quarter of 2021. See U.S. LINZESS Commercial Collaboration table at the end of the press release.\n<\/li>\n<\/ul>\n<table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwtopsingle bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>U.S. LINZESS Full Brand Collaboration<\/b>\n<\/p>\n<p class=\"bwcellpmargin\">\n<i>(in thousands, except for percentages)<\/i>\n<\/p>\n<\/td>\n<td class=\"bwtopsingle bwsinglebottom bwrightsingle bwpadl0 bwalignc\" colspan=\"2\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\nThree Months Ended\n<\/p>\n<p class=\"bwalignc bwcellpmargin\">\nJune 30,\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>2022<\/b>\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>2021<\/b>\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nLINZESS U.S. net sales as reported by AbbVie\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n$248,351\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n$259,252\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nAbbVie &amp; Ironwood commercial costs, expenses and other discounts\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n76,363\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n73,439\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwrowaltcolor0 bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<i>Commercial margin<\/i>\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<i>69%<\/i>\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<i>72%<\/i>\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nAbbVie &amp; Ironwood R&amp;D Expenses\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n8,214\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n9,173\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTotal net profit on sales of LINZESS\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n163,774\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n176,640\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwrowaltcolor0 bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<i>Full brand margin<\/i>\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<i>66%<\/i>\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<i>68%<\/i>\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<ul class=\"bwlistdisc\">\n<li>\nIn June 2022, LINZESS received a strong recommendation and a high rating on certainty of evidence in the update to the American Gastroenterological Association practice guideline on the Pharmacological Management of Irritable Bowel Syndrome with Constipation (IBS-C).\n<\/li>\n<\/ul>\n<p>\n<b><span class=\"bwuline\">Recent Business Highlights<\/span><\/b>\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nIn May 2022, Ironwood completed its board authorized share repurchase program of up to $150 million. For the overall program, under which repurchases commenced in December 2021, Ironwood repurchased 13.1 million shares of Class A Common Stock at an average price per share of $11.47.\n<\/li>\n<li>\nIn June 2022, Ironwood repaid the remaining $120.7 million aggregate principal amount of the 2022 Convertible Notes in full.\n<\/li>\n<\/ul>\n<p>\n<b><span class=\"bwuline\">Pipeline Updates<\/span><\/b>\n<\/p>\n<p>\n<b>Pediatric Program<\/b>\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nIronwood and AbbVie are currently advancing the linaclotide clinical pediatric program to potentially expand the clinical profile of LINZESS (assuming positive data and FDA approval).\n<\/li>\n<\/ul>\n<p class=\"bwmarginl1\">\n\u2013 The functional constipation study in 6- to 17-year-olds is expected to readout in the third quarter of 2022. There are currently no FDA approved prescription pediatric therapies for functional constipation.\n<\/p>\n<p>\n<b>IW-3300<\/b>\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nIronwood is currently advancing IW-3300, a guanylate cyclase-C agonist being developed for the potential treatment of visceral pain conditions, such as interstitial cystitis \/ bladder pain syndrome (IC\/BPS) and endometriosis.\n<\/li>\n<\/ul>\n<p class=\"bwmarginl1\">\n\u2013 Ironwood has successfully completed Phase I studies to evaluate the safety and tolerability of IW-3300 in healthy volunteers and expects to initiate a Phase 2 proof of concept study in IC\/BPS patients by the end of 2022.\n<\/p>\n<p>\n<b>CNP-104<\/b>\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nIronwood has a collaboration and license option agreement with COUR Pharmaceuticals Development Company, Inc. (\u201cCOUR\u201d). This agreement gives Ironwood an option to acquire an exclusive license to research, develop, manufacture and commercialize, in the U.S., products containing CNP-104 (\u201cCNP-104\u201d), a tolerizing immune modifying nanoparticle, for the treatment of primary biliary cholangitis (\u201cPBC\u201d), a rare autoimmune disease targeting the liver. If successful, CNP-104 has the potential to be the first approved PBC disease modifying therapy.\n<\/li>\n<\/ul>\n<p class=\"bwmarginl1\">\n\u2013 COUR is currently conducting a clinical study for CNP-104 evaluating the safety, tolerability, pharmacodynamic effects and efficacy of CNP-104 in PBC patients, and remains on track with a data readout estimated in 2023.\n<\/p>\n<p>\n<b>Second Quarter Financial Results<\/b>\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\n<b>Total Revenues.<\/b> Total revenues in the second quarter of 2022 were $97.2 million, compared to $104.0 million in the second quarter of 2021.\n<\/li>\n<\/ul>\n<p class=\"bwmarginl1\">\n\u2013 Total revenues in the second quarter of 2022 consisted of $94.5 million associated with Ironwood\u2019s share of the net profits from the sales of LINZESS in the U.S. and $2.7 million in royalties and other revenue. Total revenues in the second quarter of 2021 consisted of $100.3 million associated with Ironwood\u2019s share of the net profits from the sales of LINZESS in the U.S., and $3.7 million in linaclotide royalties and other revenue.\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\n<b>Operating Expenses<\/b>. Operating expenses in the second quarter of 2022 were $41.6 million, compared to $38.9 million in the second quarter of 2021.\n<\/li>\n<\/ul>\n<p class=\"bwmarginl1\">\n\u2013 Operating expenses in the second quarter of 2022 consisted of $30.1 million in selling, general and administrative (\u201cSG&amp;A\u201d) expenses, and $11.5 million in research and development (\u201cR&amp;D\u201d) expenses. Operating expenses in the second quarter of 2021 consisted of $27.0 million in SG&amp;A expenses and $12.2 million in R&amp;D expenses, partially offset by a $0.3 million adjustment to restructuring expenses.\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\n<b>Interest Expense, net of Interest and Investment Income. <\/b>Net interest expense was $2.2 million in the second quarter of 2022, primarily in connection with Ironwood\u2019s convertible senior notes, partially offset by $1.0 million of investment income. Interest expense recorded in the second quarter of 2022 included $1.7 million in cash expense and $0.5 million in non-cash expense. Net interest expense was $7.6 million in the second quarter of 2021, primarily in connection with Ironwood\u2019s convertible senior notes. Interest expense recorded in the second quarter of 2021 included $1.8 million in cash expense and $5.9 million in non-cash expense. The reduction in non-cash interest expense in the second quarter of 2022 relates to the adoption of ASU No. 2020-06, <i>Debt\u2014Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging\u2014 Contracts in Entity\u2019s Own Equity (Subtopic 815-40): Accounting for Convertible Instruments and Contracts in an Entity\u2019s Own Equity<\/i> (\u201cASU 2020-06\u201d) on January 1, 2022, that impacts the accounting for Ironwood\u2019s convertible senior notes.<br \/>\n\n<\/li>\n<\/ul>\n<ul class=\"bwlistdisc\">\n<li>\n<b>Loss on Derivatives.<\/b> Ironwood recorded a loss on derivatives of $0.7 million in the second quarter of 2022, as a result of the change in fair value of its convertible note hedges and note hedge warrants. The convertible note hedges terminated unexercised upon expiration in June 2022. Ironwood recorded a loss on derivatives of $3.2 million in the second quarter of 2021, as a result of the change in fair value of its convertible note hedges and note hedge warrants.<br \/>\n\n<\/li>\n<\/ul>\n<ul class=\"bwlistdisc\">\n<li>\n<b>Income Tax Expense. <\/b>Ironwood recorded $16.7 million of income tax expense in the second quarter of 2022, the majority of which was non-cash, as Ironwood continues to utilize net operating losses to offset taxable income for federal purposes and in many states. Ironwood recorded $336.9 million of income tax benefit in the second quarter of 2021, primarily related to the release of its valuation allowance against the majority of its deferred tax assets. Ironwood maintained a valuation allowance on the majority of its net deferred tax assets until the second quarter of 2021.<br \/>\n\n<\/li>\n<\/ul>\n<ul class=\"bwlistdisc\">\n<li>\n<b>GAAP Net Income. <\/b>GAAP net income was $37.1 million, or $0.24 per share (basic) and $0.21 per share (diluted), in the second quarter of 2022 compared to GAAP net income of $391.3 million, or $2.42 per share (basic) and $2.39 per share (diluted) in the second quarter of 2021.<br \/>\n\n<\/li>\n<\/ul>\n<ul class=\"bwlistdisc\">\n<li>\n<b>Non-GAAP Net Income. <\/b>Non-GAAP net income was $37.8 million, or $0.24 per share (basic) and $0.21 per share (diluted), in the second quarter of 2022, compared to non-GAAP net income of $56.4 million, or $0.35 per share (basic) and $0.34 per share (diluted), in the second quarter of 2021.\n<\/li>\n<\/ul>\n<p>\nNon-GAAP net income excludes the impact of mark-to-market adjustments on the derivatives related to Ironwood\u2019s 2022 Convertible Notes, restructuring expenses, and the release of the company\u2019s valuation allowance against the majority of deferred tax assets in the second quarter of 2021. See Non-GAAP Financial Measures below.\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\n<b>Adjusted EBITDA<\/b>. Adjusted EBITDA was $56.0 million in the second quarter of 2022, compared to $65.2 million in the second quarter of 2021.\n<\/li>\n<\/ul>\n<p class=\"bwmarginl1\">\n\u2013 Adjusted EBITDA is calculated by subtracting mark-to-market adjustments on derivatives related to Ironwood\u2019s 2022 Convertible Notes, restructuring expenses, net interest expense, income taxes, depreciation and amortization from GAAP net income. See Non-GAAP Financial Measures below.\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\n<b>Cash Flow Highlights. <\/b>Ironwood ended the second quarter of 2022 with $504.4 million of cash and cash equivalents.\n<\/li>\n<\/ul>\n<p class=\"bwmarginl1\">\n\u2013 Ironwood generated $61.4 million in cash from operations in the second quarter of 2022, compared to $48.6 million in cash from operations in the second quarter of 2021.\n<\/p>\n<p class=\"bwmarginl1\">\n\u2013 Ironwood used $120.7 million of cash to repay the remaining aggregate principal amount of the 2022 Convertible Notes and $33.9 million of cash to repurchase shares of its Class A Common Stock in the second quarter of 2022.\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\n<b>Ironwood 2022 Financial Guidance. <\/b>In 2022, Ironwood continues to expect:\n<\/li>\n<\/ul>\n<table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwtopsingle bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwtopsingle bwsinglebottom bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>2022 Guidance<\/b>\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nU.S. LINZESS Net Sales Growth\n<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\nLow single digits %\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTotal Revenue\n<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n$420 to $430 million\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nAdjusted EBITDA<sup>1<\/sup>\n<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n&gt;$250 million\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n<sup>1 <\/sup>Adjusted EBITDA is calculated by subtracting mark-to-market adjustments on derivatives related to Ironwood\u2019s 2022 Convertible Notes, restructuring expenses, net interest expense, income taxes, depreciation and amortization from GAAP net income. For purposes of this guidance, Ironwood has assumed that it will not incur material expenses related to business development activities in 2022.\n<\/p>\n<p>\n<b>Non-GAAP Financial Measures<\/b>\n<\/p>\n<p>\nIronwood presents non-GAAP net income and non-GAAP net income per share to exclude the impact of net gains and losses on derivatives related to Ironwood\u2019s 2022 Convertible Notes that are required to be marked-to-market, restructuring expenses, and the release of the company\u2019s valuation allowance\n<\/p>\n<p>\nagainst the majority of deferred tax assets in the second quarter of 2021. Non-GAAP adjustments are further detailed below:\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nThe gains and losses on the derivatives related to Ironwood\u2019s 2022 Convertible Notes were highly variable, difficult to predict and of a size that could have a substantial impact on the company\u2019s reported results of operations in any given period.\n<\/li>\n<li>\nRestructuring expenses are considered to be a non-recurring event as they are associated with distinct operational decisions. Included in restructuring expenses are costs associated with exit and disposal activities.\n<\/li>\n<li>\nThe income tax benefit associated with the valuation allowance release in the second quarter of 2021 was a non-cash, non-recurring accounting recognition event, and does not affect the company\u2019s ability to utilize its historical net operating losses and tax credit carryforwards to offset future taxable income.\n<\/li>\n<\/ul>\n<p>\nIronwood also presents adjusted EBITDA, a non-GAAP measure, as well as guidance on adjusted EBITDA. Adjusted EBITDA is calculated by subtracting mark-to-market adjustments on derivatives related to Ironwood\u2019s 2022 Convertible Notes, restructuring expenses, net interest expense, income taxes, depreciation and amortization from GAAP net income. The adjustments are made on a similar basis as described above related to non-GAAP net income, as applicable.\n<\/p>\n<p>\nManagement believes this non-GAAP information is useful for investors, taken in conjunction with Ironwood\u2019s GAAP financial statements, because it provides greater transparency and period-over-period comparability with respect to Ironwood\u2019s operating performance. These measures are also used by management to assess the performance of the business. Investors should consider these non-GAAP measures only as a supplement to, not as a substitute for or as superior to, measures of financial performance prepared in accordance with GAAP. In addition, these non-GAAP financial measures are unlikely to be comparable with non-GAAP information provided by other companies. For a reconciliation of non-GAAP net income and non-GAAP net income per share to GAAP net income and GAAP net income per share, respectively, and for a reconciliation of adjusted EBITDA to GAAP net income, please refer to the tables at the end of this press release.\n<\/p>\n<p>\nIronwood does not provide guidance on GAAP net income or a reconciliation of expected adjusted EBITDA to expected GAAP net income because, without unreasonable efforts, it is unable to predict with reasonable certainty the non-GAAP adjustments used to calculate adjusted EBITDA. These adjustments are uncertain, depend on various factors and could have a material impact on GAAP net income for the guidance period.\n<\/p>\n<p>\n<b>Conference Call Information<\/b>\n<\/p>\n<p>\nIronwood will host a conference call and webcast at 8:30 a.m. Eastern Time on Thursday, August 4, 2022 to discuss its second quarter 2022 results and recent business activities. Individuals interested in participating in the call should dial (888) 330-2384 (U.S. and Canada) or (240) 789-2701 (international) using conference ID number and event passcode 4671230. To access the webcast, please visit the Investors section of Ironwood\u2019s website at <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.ironwoodpharma.com&amp;esheet=52800638&amp;newsitemid=20220804005059&amp;lan=en-US&amp;anchor=www.ironwoodpharma.com&amp;index=2&amp;md5=c06f23bccf36fb57c4484ec7d24b08f8\" rel=\"nofollow noopener\" shape=\"rect\">www.ironwoodpharma.com<\/a> at least 15 minutes prior to the start of the call to ensure adequate time for any software downloads that may be required. The call will be available for replay via telephone starting at approximately 11:30 a.m. Eastern Time on August 4, 2022 running through 11:59 p.m. Eastern Time on August 18, 2022. To listen to the replay, dial (800) 770-2030 (U.S. and Canada) or (647) 362-9199 (international) using conference ID number 4671230. The archived webcast will be available on Ironwood\u2019s website for 14 days beginning approximately one hour after the call has completed.\n<\/p>\n<p>\n<b>About Ironwood Pharmaceuticals<\/b>\n<\/p>\n<p>\nIronwood Pharmaceuticals (Nasdaq: IRWD), an S&amp;P SmallCap 600\u00ae company, is a leading gastrointestinal (GI) healthcare company on a mission to advance the treatment of GI diseases and redefine the standard of care for GI patients. We are pioneers in the development of LINZESS\u00ae (linaclotide), the U.S. branded prescription market leader for adults with irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC). Under the guidance of our seasoned industry leaders, we continue to build upon our history of GI innovation and challenge what has been done before to shape what the future holds. We keep patients at the heart of our R&amp;D and commercialization efforts to reduce the burden of GI diseases and address significant unmet needs.\n<\/p>\n<p>\nFounded in 1998, Ironwood Pharmaceuticals is headquartered in Boston, Massachusetts.\n<\/p>\n<p>\nWe routinely post information that may be important to investors on our website at <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Furldefense.com%2Fv3%2F__http%3A%2Fwww.ironwoodpharma.com__%3B%21%21HhhKMSGjjQV-%21sPphJvgVNqjQfZT7uXoOEOoOouygSEjtDO7aE_n_dUW79EER_fbysRCy15P4mXIkTwuklisX-w%24&amp;esheet=52800638&amp;newsitemid=20220804005059&amp;lan=en-US&amp;anchor=www.ironwoodpharma.com&amp;index=3&amp;md5=f218d87cb26a5ad2c96a8afbecdef256\" rel=\"nofollow noopener\" shape=\"rect\">www.ironwoodpharma.com<\/a>. In addition, follow us on <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ftwitter.com%2Fironwoodpharma&amp;esheet=52800638&amp;newsitemid=20220804005059&amp;lan=en-US&amp;anchor=Twitter&amp;index=4&amp;md5=f14b66040b356b88929c89ffe091dab9\" rel=\"nofollow noopener\" shape=\"rect\">Twitter<\/a> and on <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fironwood-pharmaceuticals%2F%3FviewAsMember%3Dtrue&amp;esheet=52800638&amp;newsitemid=20220804005059&amp;lan=en-US&amp;anchor=LinkedIn&amp;index=5&amp;md5=f95893b023090114d12617a4e27f4aa4\" rel=\"nofollow noopener\" shape=\"rect\">LinkedIn<\/a>.\n<\/p>\n<p>\n<b>About LINZESS (linaclotide)<\/b>\n<\/p>\n<p>\nLINZESS\u00ae is the #1 prescribed brand in the U.S. for the treatment of adult patients with irritable bowel syndrome with constipation (\u201cIBS-C\u201d) or chronic idiopathic constipation (\u201cCIC\u201d), based on IQVIA data.\n<\/p>\n<p>\nLINZESS is a once-daily capsule that helps relieve the abdominal pain, constipation, and overall abdominal symptoms of bloating, discomfort and pain associated with IBS-C, as well as the constipation, infrequent stools, hard stools, straining, and incomplete evacuation associated with CIC. The recommended dose is 290 mcg for IBS-C patients and 145 mcg for CIC patients, with a 72-mcg dose approved for use in CIC depending on individual patient presentation or tolerability. LINZESS should be taken at least 30 minutes before the first meal of the day.\n<\/p>\n<p>\nLINZESS is contraindicated in pediatric patients less than 2 years of age. In neonatal mice, linaclotide increased fluid secretion as a consequence of age-dependent elevated GC-C agonism resulting in mortality within the first 24 hours due to dehydration. There was no age-dependent trend in GC-C intestinal expression in a clinical study of children 2 to less than 18 years of age; however, there are insufficient data available on GC-C intestinal expression in children less than 2 years of age to assess the risk of developing diarrhea and its potentially serious consequences in these patients. The safety and effectiveness of LINZESS in patients less than 18 years of age have not been established.\n<\/p>\n<p>\nLINZESS is not a laxative; it is the first medicine approved by the FDA in a class called GC-C agonists. LINZESS contains a peptide called linaclotide that activates the GC-C receptor in the intestine. Activation of GC-C is thought to result in increased intestinal fluid secretion and accelerated transit and a decrease in the activity of pain-sensing nerves in the intestine. The clinical relevance of the effect on pain fibers, which is based on nonclinical studies, has not been established.\n<\/p>\n<p>\nIn the United States, Ironwood and AbbVie co-develop and co-commercialize LINZESS for the treatment of adults with IBS-C or CIC. In Europe, AbbVie markets linaclotide under the brand name CONSTELLA\u00ae for the treatment of adults with moderate to severe IBS-C. In Japan, Ironwood&#8217;s partner, Astellas, markets linaclotide under the brand name LINZESS for the treatment of adults with IBS-C or CIC. Ironwood also has partnered with AstraZeneca for development and commercialization of LINZESS in China, and with AbbVie for development and commercialization of linaclotide in all other territories worldwide.\n<\/p>\n<p>\n<b>LINZESS Important Safety Information<\/b>\n<\/p>\n<p>\n<b>INDICATIONS AND USAGE<\/b>\n<\/p>\n<p>\nLINZESS (linaclotide) is indicated in adults for the treatment of both irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC).\n<\/p>\n<table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwpadl0 bwsinglebottom\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>IMPORTANT SAFETY INFORMATION<\/b>\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>WARNING: RISK OF SERIOUS DEHYDRATION IN PEDIATRIC PATIENTS LESS THAN 2 YEARS OF AGE<\/b>\n<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<p class=\"bwcellpmargin\">\n<b>LINZESS is contraindicated in patients less than 2 years of age. In nonclinical studies in neonatal mice, administration of a single, clinically relevant adult oral dose of linaclotide caused deaths due to dehydration.<\/b>\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n<b>Contraindications<\/b>\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nLINZESS is contraindicated in patients less than 2 years of age due to the risk of serious dehydration.\n<\/li>\n<li>\nLINZESS is contraindicated in patients with known or suspected mechanical gastrointestinal obstruction.\n<\/li>\n<\/ul>\n<p>\n<b>Warnings and Precautions<\/b>\n<\/p>\n<p>\n<i>Pediatric Risk<\/i>\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nLINZESS is contraindicated in patients less than 2 years of age. In neonatal mice, linaclotide increased fluid secretion as a consequence of age-dependent elevated GC-C agonism resulting in mortality within the first 24 hours due to dehydration. There was no age-dependent trend in GC-C intestinal expression in a clinical study of children 2 to less than 18 years of age; however, there are insufficient data available on GC-C intestinal expression in children less than 2 years of age to assess the risk of developing diarrhea and its potentially serious consequences in these patients. The safety and effectiveness of LINZESS in patients less than 18 years of age have not been established.\n<\/li>\n<\/ul>\n<p>\n<i>Diarrhea<\/i>\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nDiarrhea was the most common adverse reaction in LINZESS-treated patients in the pooled IBS-C and CIC double-blind placebo-controlled trials. The incidence of diarrhea was similar in the IBS-C and CIC populations. Severe diarrhea was reported in 2% of 145 mcg and 290 mcg LINZESS-treated patients, and in &lt;1% of 72 mcg LINZESS-treated CIC patients. If severe diarrhea occurs, dosing should be suspended and the patient rehydrated.\n<\/li>\n<\/ul>\n<p>\n<b>Common Adverse Reactions <\/b>(incidence \u22652% and greater than placebo)\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nIn IBS-C clinical trials: diarrhea (20% vs 3% placebo), abdominal pain (7% vs 5%), flatulence (4% vs 2%), headache (4% vs 3%), viral gastroenteritis (3% vs 1%) and abdominal distension (2% vs 1%).\n<\/li>\n<li>\nIn CIC trials of a 145 mcg dose: diarrhea (16% vs 5% placebo), abdominal pain (7% vs 6%), flatulence (6% vs 5%), upper respiratory tract infection (5% vs 4%), sinusitis (3% vs 2%) and abdominal distension (3% vs 2%). In a CIC trial of a 72 mcg dose: diarrhea (19% vs 7% placebo) and abdominal distension (2% vs &lt;1%).\n<\/li>\n<\/ul>\n<p>\nPlease see full Prescribing Information including Boxed Warning: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.allergan.com%2Fassets%2Fpdf%2Flinzess_pi&amp;esheet=52800638&amp;newsitemid=20220804005059&amp;lan=en-US&amp;anchor=http%3A%2F%2Fwww.allergan.com%2Fassets%2Fpdf%2Flinzess_pi&amp;index=6&amp;md5=750d22684c4c0dd251006d6cd87aa98f\" rel=\"nofollow noopener\" shape=\"rect\">http:\/\/www.allergan.com\/assets\/pdf\/linzess_pi<\/a>\n<\/p>\n<p>\nLINZESS\u00ae and CONSTELLA\u00ae are registered trademarks of Ironwood Pharmaceuticals, Inc. Any other trademarks referred to in this press release are the property of their respective owners. All rights reserved.\n<\/p>\n<p>\n<b>Forward-Looking Statements<\/b>\n<\/p>\n<p>\nThis press release contains forward-looking statements. Investors are cautioned not to place undue reliance on these forward-looking statements, including statements about Ironwood\u2019s ability to execute its mission; Ironwood\u2019s strategy, business, financial position and operations; Ironwood\u2019s ability to drive growth and profitability; the demand, development, commercial availability and commercial potential of linaclotide and the drivers, timing, impact and results thereof; Ironwood\u2019s continued focused investments and commitment to reaching new patients to drive prescription demand growth moving forward, which include a clinical pediatric programs in IBS-C and functional constipation (including the timing and results thereof); the potential indications for, and benefits of, linaclotide; financial performance and results, and guidance and expectations related thereto, including expectations related to LINZESS U.<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\nInvestors:<br \/>\n<br \/>Greg Martini, 617-374-5230<br \/>\n<br \/><a target=\"_blank\" href=\"&#109;&#x61;&#105;&#x6c;&#116;&#x6f;&#58;&#x67;m&#x61;r&#x74;i&#x6e;i&#64;&#x69;&#114;&#x6f;&#110;&#x77;&#111;&#x6f;&#100;&#x70;h&#x61;r&#x6d;a&#x2e;c&#111;&#x6d;\" rel=\"nofollow noopener\" shape=\"rect\">&#103;&#x6d;&#97;&#x72;&#116;&#x69;&#110;&#x69;&#64;&#x69;&#114;&#x6f;n&#x77;o&#x6f;d&#x70;h&#x61;r&#x6d;a&#46;&#x63;&#111;&#x6d;<\/a>\n<\/p>\n<p>\nMatt Roache, 617-621-8395<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;&#97;i&#x6c;&#x74;&#111;:&#x6d;&#x72;&#111;a&#x63;&#x68;&#101;&#64;&#x69;&#x72;&#111;n&#x77;&#111;&#111;d&#x70;&#104;a&#x72;&#x6d;&#97;&#46;&#x63;&#x6f;&#109;\" rel=\"nofollow noopener\" shape=\"rect\">&#109;&#x72;&#x6f;a&#99;&#x68;&#x65;&#64;&#105;&#x72;o&#110;&#x77;&#x6f;o&#100;&#x70;h&#97;&#x72;&#x6d;a&#46;&#x63;&#x6f;&#109;<\/a>\n<\/p>\n<p>\nMedia:<br \/>\n<br \/>Beth Calitri, 978-417-2031<br \/>\n<br \/><a target=\"_blank\" href=\"m&#97;&#105;&#x6c;&#x74;o&#58;&#98;&#x63;&#x61;&#x6c;i&#116;&#114;&#x69;&#x40;ir&#111;&#x6e;&#x77;&#x6f;o&#100;&#112;&#x68;&#x61;rm&#97;&#x2e;&#x63;&#x6f;m\" rel=\"nofollow noopener\" shape=\"rect\">&#98;&#x63;&#x61;l&#105;&#x74;r&#105;&#x40;&#x69;r&#111;&#x6e;w&#111;&#x6f;&#x64;p&#104;&#x61;r&#109;&#x61;&#x2e;&#99;&#111;&#x6d;<\/a>\n<\/p>\n<p> <a href=\"http:\/\/www.businesswire.com\/news\/home\/20220804005059\/en\/Ironwood-Pharmaceuticals-Reports-Second-Quarter-2022-Results-Maintains-Full-Year-Guidance-Due-to-Continued-Strength-of-LINZESS%C2%AE-Prescription-Demand\/?feedref=Zd8jjkgYuzBwDixoAdXmJgT1albrG1Eq4mAeVP392103_ypKzv-7ah0oHKWbnuHnevRMp3sIgu8q3wq1OF24lT93qbEzrwa15HGbLqMObxZM7XiMhduiSeKMTNDLRqI_doMC3CVAuyHo5cJ7XfDuvA==\"> Read full story here <\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u2013 LINZESS (Iinaclotide) EUTRx prescription demand growth in Q2 2022 increased 9% year-over-year \u2013 \u2013 GAAP net income of $37 million and adjusted EBITDA of $56 million; ended Q2 2022 with $504 million in cash and cash equivalents \u2013 \u2013 Completes Board of Directors authorized share repurchase program; repays remaining principal amount of the 2022 &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-46929","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"\u2013 LINZESS (Iinaclotide) EUTRx prescription demand growth in Q2 2022 increased 9% year-over-year \u2013 \u2013 GAAP net income of $37 million and adjusted EBITDA of $56 million; ended Q2 2022 with $504 million in cash and cash equivalents \u2013 \u2013 Completes Board of Directors authorized share repurchase program; repays remaining principal amount of the 2022 ... [Read more...]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/\" \/>\n<meta property=\"og:site_name\" content=\"Pharma Trend\" \/>\n<meta property=\"article:published_time\" content=\"2022-08-04T11:01:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mms.businesswire.com\/media\/20220804005059\/en\/618520\/21\/IRWD_Logo_Color_Vertical_RD_RGB.jpg\" \/>\n<meta name=\"author\" content=\"Business Wire\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Business Wire\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"17 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/\"},\"author\":{\"name\":\"Business Wire\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/person\\\/02d41342c7a74fa7f0032bb35ef0bb24\"},\"headline\":\"Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand\",\"datePublished\":\"2022-08-04T11:01:46+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/\"},\"wordCount\":3499,\"publisher\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20220804005059\\\/en\\\/618520\\\/21\\\/IRWD_Logo_Color_Vertical_RD_RGB.jpg\",\"articleSection\":[\"Industry\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/\",\"url\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/\",\"name\":\"Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand - Pharma Trend\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20220804005059\\\/en\\\/618520\\\/21\\\/IRWD_Logo_Color_Vertical_RD_RGB.jpg\",\"datePublished\":\"2022-08-04T11:01:46+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/#primaryimage\",\"url\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20220804005059\\\/en\\\/618520\\\/21\\\/IRWD_Logo_Color_Vertical_RD_RGB.jpg\",\"contentUrl\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20220804005059\\\/en\\\/618520\\\/21\\\/IRWD_Logo_Color_Vertical_RD_RGB.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/\",\"name\":\"Pharma Trend\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#organization\",\"name\":\"Pharma Trend\",\"url\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Pharma Trend\"},\"image\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/person\\\/02d41342c7a74fa7f0032bb35ef0bb24\",\"name\":\"Business Wire\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand - Pharma Trend","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/","og_locale":"en_US","og_type":"article","og_title":"Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand - Pharma Trend","og_description":"\u2013 LINZESS (Iinaclotide) EUTRx prescription demand growth in Q2 2022 increased 9% year-over-year \u2013 \u2013 GAAP net income of $37 million and adjusted EBITDA of $56 million; ended Q2 2022 with $504 million in cash and cash equivalents \u2013 \u2013 Completes Board of Directors authorized share repurchase program; repays remaining principal amount of the 2022 ... [Read more...]","og_url":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/","og_site_name":"Pharma Trend","article_published_time":"2022-08-04T11:01:46+00:00","og_image":[{"url":"https:\/\/mms.businesswire.com\/media\/20220804005059\/en\/618520\/21\/IRWD_Logo_Color_Vertical_RD_RGB.jpg","type":"","width":"","height":""}],"author":"Business Wire","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Business Wire","Est. reading time":"17 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/#article","isPartOf":{"@id":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/"},"author":{"name":"Business Wire","@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/person\/02d41342c7a74fa7f0032bb35ef0bb24"},"headline":"Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand","datePublished":"2022-08-04T11:01:46+00:00","mainEntityOfPage":{"@id":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/"},"wordCount":3499,"publisher":{"@id":"https:\/\/pharma-trend.com\/en\/#organization"},"image":{"@id":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/#primaryimage"},"thumbnailUrl":"https:\/\/mms.businesswire.com\/media\/20220804005059\/en\/618520\/21\/IRWD_Logo_Color_Vertical_RD_RGB.jpg","articleSection":["Industry"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/","url":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/","name":"Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand - Pharma Trend","isPartOf":{"@id":"https:\/\/pharma-trend.com\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/#primaryimage"},"image":{"@id":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/#primaryimage"},"thumbnailUrl":"https:\/\/mms.businesswire.com\/media\/20220804005059\/en\/618520\/21\/IRWD_Logo_Color_Vertical_RD_RGB.jpg","datePublished":"2022-08-04T11:01:46+00:00","breadcrumb":{"@id":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/#primaryimage","url":"https:\/\/mms.businesswire.com\/media\/20220804005059\/en\/618520\/21\/IRWD_Logo_Color_Vertical_RD_RGB.jpg","contentUrl":"https:\/\/mms.businesswire.com\/media\/20220804005059\/en\/618520\/21\/IRWD_Logo_Color_Vertical_RD_RGB.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/pharma-trend.com\/en\/ironwood-pharmaceuticals-reports-second-quarter-2022-results-maintains-full-year-guidance-due-to-continued-strength-of-linzess-prescription-demand\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/pharma-trend.com\/en\/"},{"@type":"ListItem","position":2,"name":"Ironwood Pharmaceuticals Reports Second Quarter 2022 Results; Maintains Full Year Guidance Due to Continued Strength of LINZESS\u00ae Prescription Demand"}]},{"@type":"WebSite","@id":"https:\/\/pharma-trend.com\/en\/#website","url":"https:\/\/pharma-trend.com\/en\/","name":"Pharma Trend","description":"","publisher":{"@id":"https:\/\/pharma-trend.com\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/pharma-trend.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/pharma-trend.com\/en\/#organization","name":"Pharma Trend","url":"https:\/\/pharma-trend.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Pharma Trend"},"image":{"@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/person\/02d41342c7a74fa7f0032bb35ef0bb24","name":"Business Wire"}]}},"_links":{"self":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/posts\/46929","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/comments?post=46929"}],"version-history":[{"count":0,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/posts\/46929\/revisions"}],"wp:attachment":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/media?parent=46929"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/categories?post=46929"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/tags?post=46929"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}