{"id":48842,"date":"2022-09-27T08:02:15","date_gmt":"2022-09-27T06:02:15","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/rd-day-presentations-to-highlight-transgenes-competitive-positioning-capabilities-to-engineer-novel-immunotherapies-for-patients-with-cancer-and-update-on-initial-clinical-data\/"},"modified":"2022-09-27T08:02:15","modified_gmt":"2022-09-27T06:02:15","slug":"rd-day-presentations-to-highlight-transgenes-competitive-positioning-capabilities-to-engineer-novel-immunotherapies-for-patients-with-cancer-and-update-on-initial-clinical-data","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/rd-day-presentations-to-highlight-transgenes-competitive-positioning-capabilities-to-engineer-novel-immunotherapies-for-patients-with-cancer-and-update-on-initial-clinical-data\/","title":{"rendered":"R&amp;D Day: Presentations to Highlight Transgene\u2019s Competitive Positioning, Capabilities to Engineer Novel Immunotherapies for Patients with Cancer, and Update on Initial Clinical Data"},"content":{"rendered":"<div>\n<p>\nMeeting to highlight Company\u2019s innovative portfolio, supported by updated clinical data, demonstrating the potential of therapeutic vaccine and oncolytic virus candidates to improve cancer patient outcomes\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20220926005562\/en\/1192643\/5\/Logo_Transgene.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20220926005562\/en\/1192643\/21\/Logo_Transgene.jpg\"><\/a><\/p>\n<p>STRASBOURG, France&#8211;(BUSINESS WIRE)&#8211;<a href=\"https:\/\/twitter.com\/hashtag\/HBV?src=hash\" target=\"_blank\" rel=\"noopener\">#HBV<\/a>&#8211;Regulatory News:\n<\/p>\n<p>\n<b>Transgene (Euronext Paris: TNG) (Paris:TNG), <\/b>a biotech company that designs and develops virus-based immunotherapeutics against cancer, will host today an R&amp;D event for investors and research analysts in Paris.\n<\/p>\n<p>\n<b>Hedi Ben Brahim, CEO of Transgene<\/b>, commenting on the Company\u2019s R&amp;D Day said: <i>\u201cToday\u2019s event will highlight our world leading scientific and translational expertise which has allowed us to design the next generation of virus-based immunotherapies against cancer. We will provide updated data on the previous Phase Ib\/II trial of TG4001 and avelumab in HPV16-positive cancer patients and the updated clinical follow up of patients enrolled in the two Phase I trials with TG4050, which are all positive and consistent with previous findings. In addition, we will outline the progress we have made with our exciting Invir.IO\u2122 platform, which via intravenous administration could significantly broaden the potential of oncolytic viral therapies. I would like to thank our expert speakers for participating in our R&amp;D event which I am confident will demonstrate that Transgene remains on track to deliver a number of important value adding clinical milestones over the next 18 months.\u201d<\/i>\n<\/p>\n<p>\nThe event, which features presentations by leading clinicians and scientists from around the world, as well as key members of the Transgene management team, provides insights on:\n<\/p>\n<p>\n&#8211; <b>TG4001<\/b>, with updated data from the previous trial (Phase Ib\/II) evaluating the combination of TG4001 and avelumab in HPV16-positive cancers;<br \/>\n<br \/>&#8211; <b>TG4050<\/b>, with updated follow up data from the two Phase I trials in ovarian cancer and head and neck cancer;<br \/>\n<br \/>&#8211; <b>The progress of the Invir.IO\u2122 platform<\/b>, with a focus on a novel oncolytic virus vectorizing human IL-12 that has been designed to be administered intravenously.\n<\/p>\n<p>\n<b>The R&amp;D Day\u2019s key speakers, which also includes key members of Transgene\u2019s management team, are:<\/b>\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nJean-Pierre Delord, MD, PhD, General Manager of IUCT Oncopole of Toulouse, will present: \u201cTG4001 &#8211; a HPV16 Therapeutic vaccine in Phase II\u201d.\n<\/li>\n<li>\nChristian Ottensmeier, MD, PhD, FRCP, Professor of Immuno-oncology at the University of Liverpool, The Clatterbridge Cancer Center NHS Foundation Trust, will present: \u201cFrom the design of the <i>myvac<\/i>\u00ae platform to first immunological and clinical readouts, Update on the head and neck trial of TG4050\u201d.\n<\/li>\n<li>\nMatthew Block, MD, PhD, Medical oncologist at the Mayo Clinic, will present: \u201cTG4050, a personalized therapeutic vaccine in the treatment of ovarian cancer\u201d.\n<\/li>\n<li>\nAdel Samson, MD, PhD, Clinical Associate Professor, CRUK Clinician Scientist and Honorary Medical Oncologist from the University of Leeds, will present: \u201cAssessing novel routes of administration (IV or locoregional route) with TG6002\u201d.\n<\/li>\n<li>\nPedro Romero, MD, Chief Editor of the JITC and Deputy scientific managing director of the Lausanne Branch of the Ludwig Institute for Cancer Research, will present: \u201cOpportunities in the immuno-oncology field\u201d.\n<\/li>\n<\/ul>\n<p>\nThe full agenda of the Transgene R&amp;D Day can be accessed on Transgene\u2019s website, <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.transgene.fr&amp;esheet=52926165&amp;newsitemid=20220926005562&amp;lan=en-US&amp;anchor=www.transgene.fr&amp;index=1&amp;md5=d6e403c1599d9eaa835c0573eb76b6be\" rel=\"nofollow noopener\" shape=\"rect\">www.transgene.fr<\/a>, in the Investor Events and presentation section.\n<\/p>\n<p>\nThe live webcast will also be accessible via the following link: <span class=\"bwuline\"><b><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fchannel.royalcast.com%2Ftransgene%2F%23%21%2Ftransgene%2F20220927_1&amp;esheet=52926165&amp;newsitemid=20220926005562&amp;lan=en-US&amp;anchor=R%26amp%3BD+Day+live+presentation&amp;index=2&amp;md5=a5e4f719c250c03d52a3edea26a39e6b\" rel=\"nofollow noopener\" shape=\"rect\">R&amp;D Day live presentation<\/a><\/b><\/span><b>.<\/b>\n<\/p>\n<p class=\"bwalignc\">\n***\n<\/p>\n<p>\n<b><i>About Transgene<br \/>\n<br \/><\/i><\/b>Transgene (Euronext: TNG) is a biotechnology company focused on designing and developing targeted immunotherapies for the treatment of cancer. Transgene\u2019s programs utilize viral vector technology with the goal of indirectly or directly killing cancer cells.<br \/>\n<br \/>The Company\u2019s clinical-stage programs consist of two therapeutic vaccines (TG4001 for the treatment of HPV-positive cancers, and TG4050, the first individualized therapeutic vaccine based on the <i>myvac<\/i>\u00ae platform) as well as two oncolytic viruses (TG6002 for the treatment of solid tumors, and BT-001, the first oncolytic virus based on the Invir.IO\u2122 platform).<br \/>\n<br \/>With Transgene\u2019s <i>myvac<\/i>\u00ae platform, therapeutic vaccination enters the field of precision medicine with a novel immunotherapy that is fully tailored to each individual. The <i>myvac<\/i>\u00ae approach allows the generation of a virus-based immunotherapy that encodes patient-specific mutations identified and selected by Artificial Intelligence capabilities provided by its partner NEC.<br \/>\n<br \/>With its proprietary platform Invir.IO\u2122, Transgene is building on its viral vector engineering expertise to design a new generation of multifunctional oncolytic viruses. Transgene has an ongoing Invir.IO\u2122 collaboration with AstraZeneca.<br \/>\n<br \/>Additional information about Transgene is available at: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.transgene.fr%2F&amp;esheet=52926165&amp;newsitemid=20220926005562&amp;lan=en-US&amp;anchor=www.transgene.fr&amp;index=3&amp;md5=6979e50231dce2199ce932025a1258eb\" rel=\"nofollow noopener\" shape=\"rect\">www.transgene.fr<\/a>. Follow us on Twitter: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ftwitter.com%2Ftransgenesa&amp;esheet=52926165&amp;newsitemid=20220926005562&amp;lan=en-US&amp;anchor=%40TransgeneSA&amp;index=4&amp;md5=51f3dbe552cb2468e9cb7a7cbb7156ea\" rel=\"nofollow noopener\" shape=\"rect\">@TransgeneSA<\/a>\n<\/p>\n<p>\n<b><i>Transgene disclaimer<br \/>\n<br \/><\/i><\/b><i>This press release contains forward-looking statements, which are subject to numerous risks and uncertainties, which could cause actual results to differ materially from those anticipated. The occurrence of any of these risks could have a significant negative outcome for the Company\u2019s activities, perspectives, financial situation, results, regulatory authorities\u2019 agreement with development phases, and development. The Company\u2019s ability to commercialize its products depends on but is not limited to the following factors: positive pre-clinical data may not be predictive of human clinical results, the success of clinical studies, the ability to obtain financing and\/or partnerships for product manufacturing, development and commercialization, and marketing approval by government regulatory authorities. For a discussion of risks and uncertainties which could cause the Company\u2019s actual results, financial condition, performance or achievements to differ from those contained in the forward-looking statements, please refer to the Risk Factors (\u201cFacteurs de Risque\u201d) section of the Universal Registration Document, available on the AMF website (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.amf-france.org&amp;esheet=52926165&amp;newsitemid=20220926005562&amp;lan=en-US&amp;anchor=http%3A%2F%2Fwww.amf-france.org&amp;index=5&amp;md5=270ebb834c4e85bbcd7655b981fd9731\" rel=\"nofollow noopener\" shape=\"rect\">http:\/\/www.amf-france.org<\/a>) or on Transgene\u2019s website (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.transgene.fr&amp;esheet=52926165&amp;newsitemid=20220926005562&amp;lan=en-US&amp;anchor=www.transgene.fr&amp;index=6&amp;md5=382d441942576fa2fd90483fbde7096f\" rel=\"nofollow noopener\" shape=\"rect\">www.transgene.fr<\/a>). Forward-looking statements speak only as of the date on which they are made, and Transgene undertakes no obligation to update these forward-looking statements, even if new information becomes available in the future.<\/i>\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\n<b>Transgene:<\/b><br \/><b>Lucie Larguier<\/b><br \/>Director Corporate Communications &amp; IR<br \/>\n<br \/>+33 (0)3 88 27 91 04<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;&#97;i&#x6c;&#116;&#111;&#x3a;&#x69;&#110;v&#x65;&#115;t&#x6f;&#x72;&#114;e&#x6c;&#97;t&#x69;&#x6f;&#110;s&#x40;&#116;r&#x61;&#x6e;&#115;g&#x65;&#110;e&#x2e;&#x66;&#114;\" rel=\"nofollow noopener\" shape=\"rect\">&#x69;&#110;v&#x65;&#x73;&#116;o&#x72;&#x72;&#101;l&#x61;&#x74;&#105;o&#x6e;&#x73;&#64;t&#x72;&#97;&#110;s&#x67;&#101;n&#x65;&#x2e;&#102;r<\/a>\n<\/p>\n<p>\n<b>Media Transgene:<\/b><br \/><b>MEDiSTRAVA Consulting<\/b><br \/><b>David Dible\/Sylvie Berrebi<\/b><br \/>+44 (0)203 928 6900<br \/>\n<br \/><a target=\"_blank\" href=\"&#109;a&#x69;l&#x74;o&#x3a;&#116;&#x72;&#97;&#x6e;&#115;g&#x65;n&#x65;&#64;&#x6d;&#101;&#x64;&#105;&#x73;&#116;&#x72;&#97;v&#x61;&#46;&#x63;o&#x6d;\" rel=\"nofollow noopener\" shape=\"rect\">&#116;&#x72;&#97;&#x6e;s&#103;&#x65;&#110;&#x65;&#64;&#x6d;e&#100;&#x69;&#115;&#x74;r&#x61;&#x76;&#97;&#x2e;c&#x6f;m<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Meeting to highlight Company\u2019s innovative portfolio, supported by updated clinical data, demonstrating the potential of therapeutic vaccine and oncolytic virus candidates to improve cancer patient outcomes STRASBOURG, France&#8211;(BUSINESS WIRE)&#8211;#HBV&#8211;Regulatory News: Transgene (Euronext Paris: TNG) (Paris:TNG), a biotech company that designs and develops virus-based immunotherapeutics against cancer, will host today an R&amp;D event for investors and &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/rd-day-presentations-to-highlight-transgenes-competitive-positioning-capabilities-to-engineer-novel-immunotherapies-for-patients-with-cancer-and-update-on-initial-clinical-data\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-48842","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>R&amp;D Day: Presentations to Highlight Transgene\u2019s Competitive Positioning, Capabilities to Engineer Novel Immunotherapies for Patients with Cancer, and Update on Initial Clinical Data - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/rd-day-presentations-to-highlight-transgenes-competitive-positioning-capabilities-to-engineer-novel-immunotherapies-for-patients-with-cancer-and-update-on-initial-clinical-data\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"R&amp;D Day: Presentations to Highlight Transgene\u2019s Competitive Positioning, Capabilities to Engineer Novel Immunotherapies for Patients with Cancer, and Update on Initial Clinical Data - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Meeting to highlight Company\u2019s innovative portfolio, supported by updated clinical data, demonstrating the potential of therapeutic vaccine and oncolytic virus candidates to improve cancer patient outcomes STRASBOURG, France&#8211;(BUSINESS WIRE)&#8211;#HBV&#8211;Regulatory News: Transgene (Euronext Paris: TNG) (Paris:TNG), a biotech company that designs and develops virus-based immunotherapeutics against cancer, will host today an R&amp;D event for investors and ... 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