{"id":49433,"date":"2022-10-10T16:01:46","date_gmt":"2022-10-10T14:01:46","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/fragile-x-syndrome-drug-pipeline-research-report-2022-comprehensive-insights-about-20-companies-and-22-pipeline-drugs-including-tetra-discovery-partners-zynerba-pharma-and-prilenia-therapeutics\/"},"modified":"2022-10-10T16:01:46","modified_gmt":"2022-10-10T14:01:46","slug":"fragile-x-syndrome-drug-pipeline-research-report-2022-comprehensive-insights-about-20-companies-and-22-pipeline-drugs-including-tetra-discovery-partners-zynerba-pharma-and-prilenia-therapeutics","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/fragile-x-syndrome-drug-pipeline-research-report-2022-comprehensive-insights-about-20-companies-and-22-pipeline-drugs-including-tetra-discovery-partners-zynerba-pharma-and-prilenia-therapeutics\/","title":{"rendered":"Fragile X Syndrome Drug Pipeline Research Report 2022: Comprehensive Insights About 20+ Companies and 22+ Pipeline Drugs Including Tetra Discovery Partners, Zynerba Pharma, and Prilenia Therapeutics &#8211; ResearchAndMarkets.com"},"content":{"rendered":"<div>\n<p>DUBLIN&#8211;(BUSINESS WIRE)&#8211;The <a target=\"_blank\" href=\"https:\/\/www.researchandmarkets.com\/reports\/4330683\/fragile-x-syndrome-pipeline-insight-2022?utm_source=BW&amp;utm_medium=PressRelease&amp;utm_code=l2g55f&amp;utm_campaign=1760304+-+Fragile+X+Syndrome+Drug+Pipeline+Research+Report+2022%3A+Comprehensive+Insights+About+20%2B+Companies+and+22%2B+Pipeline+Drugs+Including+Tetra+Discovery+Partners%2C+Zynerba+Pharma%2C+and+Prilenia+Therapeutics&amp;utm_exec=chdo54prd\" rel=\"nofollow noopener\" shape=\"rect\">&#8220;Fragile X Syndrome &#8211; Pipeline Insight, 2022&#8221;<\/a> clinical trials has been added to <strong>ResearchAndMarkets.com&#8217;s<\/strong> offering.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20221010005470\/en\/1596733\/4\/logo.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20221010005470\/en\/1596733\/21\/logo.jpg\"><\/a><\/p>\n<p>\nThe report provides comprehensive insights about 20+ companies and 22+ pipeline drugs in Fragile X Syndrome pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.\n<\/p>\n<p>\n<strong>Report Highlights<\/strong>\n<\/p>\n<p>\nThe companies and academics are working to assess challenges and seek opportunities that could influence Fragile X Syndrome R&amp;D. The therapies under development are focused on novel approaches to treat\/improve Fragile X Syndrome.\n<\/p>\n<p>\nZynerba Pharmaceuticals announced that the US Food and Drug Association has granted orphan-drug designation to ZYN002 cannabidiol (CBD) gel, for the treatment of Fragile X syndrome (FXS).\n<\/p>\n<p>\nIn March 2022, The European Commission granted orphan drug designation to Zygel, Zynerba Pharmaceuticals&#8217; cannabidiol (CBD) transdermal gel candidate to treat for behavioural symptoms in people with fragile X syndrome.\n<\/p>\n<p>\nIn February 2022, Ovid entered an option agreement with Healx for an exclusive license to gaboxadol (OV101). Healx secured from Ovid an option to exclusively license rights to develop and commercialize gaboxadol (OV101). Healx has stated that it will investigate the compound as part of a potential combination therapy for Fragile X syndrome, as well as treatment for other indications.\n<\/p>\n<p>\n<strong>Fragile X Syndrome Emerging Drugs Chapters<\/strong>\n<\/p>\n<p>\nThis segment of the Fragile X Syndrome report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.\n<\/p>\n<p>\n<strong>Fragile X Syndrome Emerging Drugs<\/strong>\n<\/p>\n<p>\n<strong>Zatolmilast: Tetra Discovery Partners<\/strong>\n<\/p>\n<p>\nTetra&#8217;s investigational new drug, named BPN14770, can selectively target and inhibit, or suppress, only the PDE4D enzyme. PDE4D plays an important role in cognition. A recent study of over a million healthy human subjects showed connections between genetic variants in PDE4D and years of educational attainment and performance on cognitive tests.\n<\/p>\n<p>\nTetra Therapeutics&#8217;s BPN14770 targets only PDE4D, and only at specific times of cellular activity. BPN14770 is designed to modulate, rather than completely inhibit, PDE4D. The desired result from clinical trial testing is two-fold: that Tetra&#8217;s BPN14770 will improve cognitive function by prolonging cAMP activity, while safety and tolerability are improved because the enzyme is not completely inhibited. Currently it is being investigated in Phase III stage of development.\n<\/p>\n<p>\n<strong>Zygel: Zynerba Pharmaceuticals<\/strong>\n<\/p>\n<p>\nZygel is the first and only pharmaceutically-produced CBD, a non-euphoric cannabinoid, formulated as a patent-protected permeation-enhanced gel for transdermal delivery through the skin and into the circulatory system.\n<\/p>\n<p>\nZygel is being developed for patients suffering from FXS, ASD in pediatric patients, 22q, and a heterogeneous group of rare and ultra-rare epilepsies known as developmental and epileptic encephalopathies (DEE). Zynerba Pharmaceuticals is conducting phase III clinical trials for the treatment of Fragile X Syndrome.\n<\/p>\n<p>\n<strong>Pridopidine: Prilenia Therapeutics<\/strong>\n<\/p>\n<p>\nPridopidine is an orally bioavailable small molecule investigational drug exhibiting potential neuroprotective effect in multiple neurodegenerative diseases with a favorable safety profile. It is the most selective high affinity Sigma-1-receptor (S1R) agonist.\n<\/p>\n<p>\nThe S1R regulates key cellular processes relevant to neurodegenerative diseases, such as calcium homeostasis, cytoskeleton dynamics, restoring mitochondrial health and neurotrophic factor release. S1R is implicated in cellular differentiation, neuroplasticity, neuroprotection, and cognitive functioning of the brain. It is in preclinical stage of development.\n<\/p>\n<p>\n<strong>Fragile X Syndrome: Therapeutic Assessment<\/strong>\n<\/p>\n<p>\nThis segment of the report provides insights about the different Fragile X Syndrome drugs segregated based on following parameters that define the scope of the report, such as:\n<\/p>\n<p>\n<strong>Major Players in Fragile X Syndrome<\/strong>\n<\/p>\n<p>\nThere are approx. 20+ key companies which are developing the therapies for Fragile X Syndrome. The companies which have their Fragile X Syndrome drug candidates in the most advanced stage, i.e. Phase III include Zynerba Pharmaceuticals and others\n<\/p>\n<p>\n<strong>Phases<\/strong>\n<\/p>\n<p>\n<strong>The report covers around 22+ products under different phases of clinical development like<\/strong>\n<\/p>\n<ul>\n<li>\nLate-stage products (Phase III)\n<\/li>\n<li>\nMid-stage products (Phase II)\n<\/li>\n<li>\nEarly-stage products (Phase I) along with the details of\n<\/li>\n<li>\nPre-clinical and Discovery stage candidates\n<\/li>\n<li>\nDiscontinued &amp; Inactive candidates\n<\/li>\n<li>\nRoute of Administration\n<\/li>\n<\/ul>\n<p>\n<strong>Products have been categorized under various ROAs such as<\/strong>\n<\/p>\n<ul>\n<li>\nInfusion\n<\/li>\n<li>\nIntradermal\n<\/li>\n<li>\nIntramuscular\n<\/li>\n<li>\nIntranasal\n<\/li>\n<li>\nIntravenous\n<\/li>\n<li>\nOral\n<\/li>\n<li>\nParenteral\n<\/li>\n<li>\nSubcutaneous\n<\/li>\n<li>\nTopical\n<\/li>\n<li>\nMolecule Type\n<\/li>\n<\/ul>\n<p>\n<strong>Products have been categorized under various Molecule types such as<\/strong>\n<\/p>\n<ul>\n<li>\nGene therapies\n<\/li>\n<li>\nSmall molecule\n<\/li>\n<li>\nVaccines\n<\/li>\n<li>\nPolymers\n<\/li>\n<li>\nPeptides\n<\/li>\n<li>\nMonoclonal antibodies\n<\/li>\n<li>\nProduct Type\n<\/li>\n<\/ul>\n<p>\n<strong>Fragile X Syndrome Report Insights<\/strong>\n<\/p>\n<ul>\n<li>\nFragile X Syndrome Pipeline Analysis\n<\/li>\n<li>\nTherapeutic Assessment\n<\/li>\n<li>\nUnmet Needs\n<\/li>\n<li>\nImpact of Drugs\n<\/li>\n<\/ul>\n<p>\n<strong>Fragile X Syndrome Report Assessment<\/strong>\n<\/p>\n<ul>\n<li>\nPipeline Product Profiles\n<\/li>\n<li>\nTherapeutic Assessment\n<\/li>\n<li>\nPipeline Assessment\n<\/li>\n<li>\nInactive drugs assessment\n<\/li>\n<li>\nUnmet Needs\n<\/li>\n<\/ul>\n<p>\n<strong>Key Players<\/strong>\n<\/p>\n<ul>\n<li>\nZynerba Pharmaceuticals\n<\/li>\n<li>\nTetra Therapeutics\n<\/li>\n<li>\nAutifony Therapeutics\n<\/li>\n<li>\nPrilenia Therapeutics\n<\/li>\n<li>\nAlcobra Ltd.\n<\/li>\n<li>\nSeaside Therapeutics, Inc.\n<\/li>\n<li>\nMarinus Pharmaceuticals\n<\/li>\n<li>\nNovartis Pharmaceuticals\n<\/li>\n<li>\nNeuren Pharmaceuticals\n<\/li>\n<li>\nHoffmann-La Roche\n<\/li>\n<li>\nHealx\n<\/li>\n<li>\nNova Mentis\n<\/li>\n<li>\nLysogene\n<\/li>\n<li>\nActinogen\n<\/li>\n<li>\nPrilenia Therapeutics\n<\/li>\n<li>\nConfluence Pharmaceuticals\n<\/li>\n<li>\nSentinel Oncology\n<\/li>\n<\/ul>\n<p>\n<strong>Key Products<\/strong>\n<\/p>\n<ul>\n<li>\nZygel\n<\/li>\n<li>\nBPN14770\n<\/li>\n<li>\nAUT00206\n<\/li>\n<li>\nPridopidine\n<\/li>\n<li>\nMG01CI\n<\/li>\n<li>\nArbaclofen\n<\/li>\n<li>\nGanaxolone\n<\/li>\n<li>\nAFQ056\n<\/li>\n<li>\nNNZ-2566\n<\/li>\n<li>\nRO4917523\n<\/li>\n<\/ul>\n<p>\nFor more information about this clinical trials report visit <a target=\"_blank\" href=\"https:\/\/www.researchandmarkets.com\/reports\/4330683\/fragile-x-syndrome-pipeline-insight-2022?utm_source=BW&amp;utm_medium=PressRelease&amp;utm_code=l2g55f&amp;utm_campaign=1760304+-+Fragile+X+Syndrome+Drug+Pipeline+Research+Report+2022%3A+Comprehensive+Insights+About+20%2B+Companies+and+22%2B+Pipeline+Drugs+Including+Tetra+Discovery+Partners%2C+Zynerba+Pharma%2C+and+Prilenia+Therapeutics&amp;utm_exec=chdo54prd\" rel=\"nofollow noopener\" shape=\"rect\">https:\/\/www.researchandmarkets.com\/r\/ooxrj0<\/a>\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\nResearchAndMarkets.com<br \/>\n<br \/>Laura Wood, Senior Press Manager<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;&#x61;&#105;l&#x74;&#x6f;&#58;pr&#x65;&#x73;&#115;&#64;&#x72;&#x65;&#115;&#101;a&#x72;&#x63;&#104;a&#x6e;&#x64;&#109;&#97;r&#x6b;&#x65;&#116;s&#x2e;&#x63;&#111;&#109;\" rel=\"nofollow noopener\" shape=\"rect\">&#x70;&#x72;&#x65;&#x73;&#x73;&#x40;&#x72;&#x65;&#x73;&#x65;&#x61;&#114;&#99;&#104;&#97;&#110;&#100;&#109;arkets&#x2e;&#x63;&#x6f;&#x6d;<\/a><\/p>\n<p>For E.S.T Office Hours Call 1-917-300-0470<br \/>\n<br \/>For U.S.\/ CAN Toll Free Call 1-800-526-8630<br \/>\n<br \/>For GMT Office Hours Call +353-1-416-8900\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>DUBLIN&#8211;(BUSINESS WIRE)&#8211;The &#8220;Fragile X Syndrome &#8211; Pipeline Insight, 2022&#8221; clinical trials has been added to ResearchAndMarkets.com&#8217;s offering. The report provides comprehensive insights about 20+ companies and 22+ pipeline drugs in Fragile X Syndrome pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/fragile-x-syndrome-drug-pipeline-research-report-2022-comprehensive-insights-about-20-companies-and-22-pipeline-drugs-including-tetra-discovery-partners-zynerba-pharma-and-prilenia-therapeutics\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-49433","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Fragile X Syndrome Drug Pipeline Research Report 2022: Comprehensive Insights About 20+ Companies and 22+ Pipeline Drugs Including Tetra Discovery Partners, Zynerba Pharma, and Prilenia Therapeutics - ResearchAndMarkets.com - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/fragile-x-syndrome-drug-pipeline-research-report-2022-comprehensive-insights-about-20-companies-and-22-pipeline-drugs-including-tetra-discovery-partners-zynerba-pharma-and-prilenia-therapeutics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fragile X Syndrome Drug Pipeline Research Report 2022: Comprehensive Insights About 20+ Companies and 22+ Pipeline Drugs Including Tetra Discovery Partners, Zynerba Pharma, and Prilenia Therapeutics - ResearchAndMarkets.com - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"DUBLIN&#8211;(BUSINESS WIRE)&#8211;The &#8220;Fragile X Syndrome &#8211; Pipeline Insight, 2022&#8221; clinical trials has been added to ResearchAndMarkets.com&#8217;s offering. 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Pipeline Insight, 2022&#8221; clinical trials has been added to ResearchAndMarkets.com&#8217;s offering. The report provides comprehensive insights about 20+ companies and 22+ pipeline drugs in Fragile X Syndrome pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product ... 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