{"id":49807,"date":"2022-10-19T16:02:13","date_gmt":"2022-10-19T14:02:13","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/tempo-bioscience-expands-patient-relevant-blood-brain-barrier-models-for-drug-development\/"},"modified":"2022-10-19T16:02:13","modified_gmt":"2022-10-19T14:02:13","slug":"tempo-bioscience-expands-patient-relevant-blood-brain-barrier-models-for-drug-development","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/tempo-bioscience-expands-patient-relevant-blood-brain-barrier-models-for-drug-development\/","title":{"rendered":"Tempo Bioscience Expands Patient-Relevant Blood-Brain-Barrier Models for Drug Development"},"content":{"rendered":"<div>\n<p>SAN FRANCISCO&#8211;(BUSINESS WIRE)&#8211;Tempo Bioscience, Inc. (\u201cTempo\u201d) a privately-held biotechnology company based in San Francisco, California, has released new human induced pluripotent stem cell (iPSC) derived cell products and affiliated cell-based services in the following categories:\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20221019005050\/en\/1605051\/4\/TempoLogo-updated2018TM_copy.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20221019005050\/en\/1605051\/21\/TempoLogo-updated2018TM_copy.jpg\"><\/a><\/p>\n<table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwpadl0 bwvertalignb\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTempo-iBMEC<sup>\u2122<\/sup>\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\">\u00a0<\/td>\n<td class=\"bwpadl0 bwvertalignb\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nHuman iPSC-derived Brain Microvascular Endothelial Cells\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwvertalignb\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTempo-iPeri<sup>\u2122<\/sup>\n<\/p>\n<\/td>\n<td colspan=\"1\" rowspan=\"1\">\u00a0<\/td>\n<td class=\"bwpadl0 bwvertalignb\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nHuman iPSC-derived Pericytes\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\nTempo-iBMEC<sup>\u2122<\/sup> and Tempo-iPeri<sup>\u2122<\/sup> are critical for establishing patient-relevant blood-brain-barrier models to improve the drug development process for a growing number of therapeutic modalities (<i>e.g.,<\/i> small molecules, biologics, gene therapies, CAR-T\/NK therapies, siRNA\/mRNA therapies). Combining these new products with existing products from Tempo, the human blood-brain-barrier is shown to be an orchestrated, dynamic and regulated barrier.\n<\/p>\n<p>\nThese new products add to the already-existing Tempo Bioscience product lines and expand the TempoStemBank<sup>\u2122 <\/sup>Disease Model offerings. Currently, more than twenty-two iPSC-derivative cell types are offered to create patient-relevant disease models. TempoATP<sup>\u2122<\/sup>, TempoMito<sup>\u2122<\/sup>, TempoCal<sup>\u2122<\/sup>, TempoO<sub>2<\/sub><sup>\u2122 <\/sup>and TempoVol<sup>\u2122<\/sup> biosensors are live-cell reporters of cellular, mitochondrial, and cytotoxicity functions.\n<\/p>\n<p>\nTempo Bioscience is the sole manufacturer of human iPSC-derived cell types that are engineered using non-viral, nucleic-acids-free, serum-free, and feeder-free technologies. Tempo is committed to advancing technologies that focus on disease modeling and drug safety evaluations using advanced human iPSC-derived cell models in 2D, as well as in 3D as spheroids or organoids. Tempo\u2019s patient-relevant cell models aim to improve drug efficacy evaluations and safety assessments during drug development.\n<\/p>\n<p>\nAbout Tempo Bioscience, Inc.: Tempo is a technology development focused biotechnology company based in San Francisco, California. Tempo develops and manufactures human iPSC-based biosensor enabling technologies for the biotech, pharmaceutical, and consumer product industries. For more information on Tempo, please visit our home page: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.tempobioscience.com%2F&amp;esheet=52946818&amp;newsitemid=20221019005050&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.tempobioscience.com&amp;index=1&amp;md5=fc2f621a69fa888e709748c9bfe0ed6d\" rel=\"nofollow noopener\" shape=\"rect\">https:\/\/www.tempobioscience.com<\/a>. Follow us on LinkedIn.\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\nTempo Bioscience, Inc.<br \/>\n<br \/>Angela L. Huang PhD; 650-731-5620\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>SAN FRANCISCO&#8211;(BUSINESS WIRE)&#8211;Tempo Bioscience, Inc. (\u201cTempo\u201d) a privately-held biotechnology company based in San Francisco, California, has released new human induced pluripotent stem cell (iPSC) derived cell products and affiliated cell-based services in the following categories: Tempo-iBMEC\u2122 \u00a0 Human iPSC-derived Brain Microvascular Endothelial Cells Tempo-iPeri\u2122 \u00a0 Human iPSC-derived Pericytes Tempo-iBMEC\u2122 and Tempo-iPeri\u2122 are critical for establishing &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/tempo-bioscience-expands-patient-relevant-blood-brain-barrier-models-for-drug-development\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-49807","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Tempo Bioscience Expands Patient-Relevant Blood-Brain-Barrier Models for Drug Development - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/tempo-bioscience-expands-patient-relevant-blood-brain-barrier-models-for-drug-development\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tempo Bioscience Expands Patient-Relevant Blood-Brain-Barrier Models for Drug Development - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"SAN FRANCISCO&#8211;(BUSINESS WIRE)&#8211;Tempo Bioscience, Inc. (\u201cTempo\u201d) a privately-held biotechnology company based in San Francisco, California, has released new human induced pluripotent stem cell (iPSC) derived cell products and affiliated cell-based services in the following categories: Tempo-iBMEC\u2122 \u00a0 Human iPSC-derived Brain Microvascular Endothelial Cells Tempo-iPeri\u2122 \u00a0 Human iPSC-derived Pericytes Tempo-iBMEC\u2122 and Tempo-iPeri\u2122 are critical for establishing ... 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