{"id":50382,"date":"2022-11-02T15:02:25","date_gmt":"2022-11-02T14:02:25","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/instem-unveils-new-additions-to-its-leading-computational-toxicology-software-suite\/"},"modified":"2022-11-02T15:02:25","modified_gmt":"2022-11-02T14:02:25","slug":"instem-unveils-new-additions-to-its-leading-computational-toxicology-software-suite","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/instem-unveils-new-additions-to-its-leading-computational-toxicology-software-suite\/","title":{"rendered":"Instem Unveils New Additions to Its Leading Computational Toxicology Software Suite"},"content":{"rendered":"<div>\n<p>\nNew Functionality Along With Enhanced Models to Deliver More Efficient and Comprehensive Predictions in Chemical Safety\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20221102005117\/en\/1620883\/5\/INSTEM-logo-JPG-uk-201021_%284%29.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20221102005117\/en\/1620883\/21\/INSTEM-logo-JPG-uk-201021_%284%29.jpg\"><\/a><\/p>\n<p>PHILADELPHIA&#8211;(BUSINESS WIRE)&#8211;<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.instem.com%2F&amp;esheet=52957611&amp;newsitemid=20221102005117&amp;lan=en-US&amp;anchor=Instem&amp;index=1&amp;md5=4b1772098765f73c8607502d83092105\" rel=\"nofollow noopener\" shape=\"rect\">Instem<\/a>, a leading provider of IT solutions and services to the global life sciences market, announced today that the latest edition of its powerful Leadscope Model Applier Computational Toxicology software solution has been released.\n<\/p>\n<p>\nThis latest update includes new functionality to provide a more seamless experience when performing a <i>Read-Across<\/i>, as well as new and updated predictive models to support the increasing market need for <i>in silico<\/i> solutions. The new release will also be used as part of the recently introduced <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Feur02.safelinks.protection.outlook.com%2F%3Furl%3Dhttps%253A%252F%252Fwww.instem.com%252Fsolutions%252Finsilico%252Fpredict.php%26data%3D05%257C01%257Cpooja.pankhania%2540instem.com%257C7dcd05dd888b4d3a827908dab5a0a633%257Ca8a9043472cd4df9beebbe60ec9e97a7%257C0%257C0%257C638021998837482318%257CUnknown%257CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%253D%257C3000%257C%257C%257C%26sdata%3D6Ug6dPI3dm06FjQjwJmtCjeQHF5Tx4vpGRnCd1iFFjE%253D%26reserved%3D0&amp;esheet=52957611&amp;newsitemid=20221102005117&amp;lan=en-US&amp;anchor=Predict%26%238482%3B+technology-enabled+service&amp;index=2&amp;md5=1c04520e16a635ec198034f27561df79\" rel=\"nofollow noopener\" shape=\"rect\">Predict\u2122 technology-enabled service<\/a> for nitrosamine carcinogenicity risk assessment.\n<\/p>\n<p>\nRenowned for their advanced informatics and prediction technology, together with comprehensive database solutions, Instem\u2019s <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.instem.com%2Fsolutions%2Finsilico%2Fcomputational-toxicology.php&amp;esheet=52957611&amp;newsitemid=20221102005117&amp;lan=en-US&amp;anchor=in+silico+solutions&amp;index=3&amp;md5=07818c777bc3fb1e012fe53690659cea\" rel=\"nofollow noopener\" shape=\"rect\"><i>in silico<\/i> solutions<\/a> enable organizations around the world to effectively unlock valuable knowledge contained in both public and proprietary sources of research data. Clients can also access well over <b>600,000<\/b> toxicology studies for more than <b>200,000<\/b> chemicals, enabling fast, accurate, defendable and regulatory-accepted predictions.\n<\/p>\n<p>\nCore features of the 2022 software release include:\n<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nNEW Read-Across Tool \u2013 a single and easy-to-use tool for searching analogs and performing read-across, while providing direct access to an extensive toxicology database.\n<\/li>\n<li>\nLeadscope Advanced\u2122 Edition \u2013 includes advanced functionality and now available online, eliminating the need to invest in computer hardware and enabling quicker, easier access to new software updates.\n<\/li>\n<li>\nUPDATED Genetox Expert Alerts \u2013 The Leadscope Expert Alerts suite for bacterial mutagenicity, widely used for <b>ICH M7<\/b> regulatory submissions, has been <b>updated<\/b> to enhance predictivity and interpretation.\n<\/li>\n<li>\nUPDATED Sensitization Models and Alerts &#8211; Updated models and alerts for the assessment of skin sensitization; including models to predict strong or extreme sensitizers formed on a growing database.\n<\/li>\n<li>\nNEW Acute Toxicity Predictive Models \u2013 New expert predictive models to predict acute lethality in dermal, oral and inhalation studies, based on research of over <b>175,000<\/b> chemicals with acute toxicity data.\n<\/li>\n<li>\nNEW Statistical Models and Expert Alerts to support the prediction of eye irritation and corrosion.\n<\/li>\n<li>\nNEW and UPDATED Statistical-Based Models to support the assessment of endocrine activity, drug permeability across the blood-brain barrier* (supporting abuse liability), and cardiac toxicity* (*developed by the US FDA under the Research Collaboration Agreement).\n<\/li>\n<\/ul>\n<p>\nDr. Glenn Myatt, VP Informatics, Instem said, \u201cWe are delighted to introduce the 2022 Computational Toxicology software release, which will further strengthen the ongoing demand for reliable alternatives to traditional testing methods.\u201d\n<\/p>\n<p>\nDr. Myatt continued, \u201cThis latest release is highly anticipated and will give both existing and prospective clients expanded support for regulatory guidelines, drug discovery, classification and labeling as well as occupational toxicology. Throughout the lifecycle of the release, we have been working in close collaboration with our clients, and feedback has been extremely positive.\u201d\n<\/p>\n<p>\nInstem has developed a comprehensive program to help raise awareness of this important 2022 software release through on-demand demonstrations and presentations at key industry events including the ACT 43<sup>rd<\/sup> Annual Meeting, November 13<sup>th<\/sup> \u2013 16<sup>th<\/sup>, Denver, Colorado.\n<\/p>\n<p>\nTo be added to the release alert list and be one of the first to receive a copy of the on-demand presentation, please email <a target=\"_blank\" href=\"&#x6d;&#x61;&#x69;&#x6c;&#116;&#111;&#58;in&#x73;&#x69;&#x6c;&#x69;&#x63;&#111;&#64;&#105;ns&#x74;&#x65;&#x6d;&#x2e;&#x63;&#111;&#109;\" rel=\"nofollow noopener\" shape=\"rect\">&#x69;&#x6e;&#115;i&#x6c;&#x69;&#99;&#111;&#64;&#x69;&#x6e;&#115;&#116;e&#x6d;&#x2e;&#99;om<\/a>\n<\/p>\n<p>\n<b>About Instem<\/b>\n<\/p>\n<p>\nA global provider of leading software solutions and scientific insight services, <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.instem.com%2Fabout%2Fwhat-we-do.php&amp;esheet=52957611&amp;newsitemid=20221102005117&amp;lan=en-US&amp;anchor=Instem+is+helping+clients&amp;index=4&amp;md5=d3e7aa8fb4184ad925e14ebdbefd9ece\" rel=\"nofollow noopener\" shape=\"rect\">Instem is helping clients<\/a> bring their life enhancing products to market faster.\n<\/p>\n<p>\nWe enable organizations in the life sciences to more efficiently collect, report and submit high quality regulatory data, while offering them the unique ability to generate new knowledge through the extraction and harmonization of actionable scientific information.\n<\/p>\n<p>\nAcross the entire drug development value chain, every day Instem solutions are meeting the rapidly expanding needs of life science organizations for data-driven decision making, leading to safer, more effective products.\n<\/p>\n<p>\nInstem supports its global roster of clients through offices in the United States, United Kingdom, France, Switzerland, Japan, China, and India.\n<\/p>\n<p>\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Finstem%2F&amp;esheet=52957611&amp;newsitemid=20221102005117&amp;lan=en-US&amp;anchor=LinkedIn&amp;index=5&amp;md5=1ecee26b1e4e25142f3397de1a51c336\" rel=\"nofollow noopener\" shape=\"rect\">LinkedIn<\/a><br \/><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ftwitter.com%2FInstemsoftware&amp;esheet=52957611&amp;newsitemid=20221102005117&amp;lan=en-US&amp;anchor=Twitter&amp;index=6&amp;md5=4cad2bf05737922395c269ab661ccc24\" rel=\"nofollow noopener\" shape=\"rect\">Twitter<\/a>\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\n<b>Press:<br \/>\n<br \/><\/b>Instem<br \/>\n<br \/>Julie Jones, Marketing Director<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;&#97;&#x69;&#x6c;t&#x6f;&#58;j&#x75;&#108;i&#x65;&#46;&#x6a;&#x6f;n&#x65;&#115;&#64;&#x69;&#110;s&#x74;&#101;&#x6d;&#x2e;&#99;&#x6f;&#x6d;\" rel=\"nofollow noopener\" shape=\"rect\">&#106;&#x75;&#108;&#x69;&#101;&#x2e;&#106;&#x6f;&#110;&#x65;&#115;&#x40;&#105;&#x6e;&#115;&#x74;&#101;&#x6d;&#46;&#x63;&#111;&#x6d;<\/a><\/p>\n<p>Pooja Pankhania, Marketing Manager \u2013 In Silico Solutions<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;&#x61;&#105;l&#x74;&#x6f;&#x3a;&#80;o&#x6f;&#x6a;&#x61;&#46;p&#x61;&#x6e;&#x6b;&#104;a&#x6e;&#x69;&#x61;&#64;i&#x6e;&#x73;&#x74;&#101;m&#x2e;&#x63;&#x6f;&#109;\" rel=\"nofollow noopener\" shape=\"rect\">&#80;&#x6f;&#111;&#x6a;&#97;&#x2e;p&#x61;n&#x6b;h&#97;&#x6e;&#105;&#x61;&#64;&#x69;&#110;&#x73;t&#x65;m&#x2e;c&#111;&#x6d;<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>New Functionality Along With Enhanced Models to Deliver More Efficient and Comprehensive Predictions in Chemical Safety PHILADELPHIA&#8211;(BUSINESS WIRE)&#8211;Instem, a leading provider of IT solutions and services to the global life sciences market, announced today that the latest edition of its powerful Leadscope Model Applier Computational Toxicology software solution has been released. This latest update includes &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/instem-unveils-new-additions-to-its-leading-computational-toxicology-software-suite\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-50382","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Instem Unveils New Additions to Its Leading Computational Toxicology Software Suite - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/instem-unveils-new-additions-to-its-leading-computational-toxicology-software-suite\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Instem Unveils New Additions to Its Leading Computational Toxicology Software Suite - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"New Functionality Along With Enhanced Models to Deliver More Efficient and Comprehensive Predictions in Chemical Safety PHILADELPHIA&#8211;(BUSINESS WIRE)&#8211;Instem, a leading provider of IT solutions and services to the global life sciences market, announced today that the latest edition of its powerful Leadscope Model Applier Computational Toxicology software solution has been released. 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