{"id":50530,"date":"2022-11-07T08:02:33","date_gmt":"2022-11-07T07:02:33","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/"},"modified":"2022-11-07T08:02:33","modified_gmt":"2022-11-07T07:02:33","slug":"transgene-reports-business-update-and-q3-2022-financial-position","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/","title":{"rendered":"Transgene Reports Business Update And Q3 2022 Financial Position"},"content":{"rendered":"<div>\n<ul class=\"bwlistdisc\">\n<li>\n<b><i>Positive result from interim analysis and reduction of the size of the Phase II trial evaluating TG4001 + avelumab vs avelumab <\/i><\/b><i>in HPV-positive anogenital cancers<\/i>\n<\/li>\n<li>\n<b><i>Positive clinical data on TG4050 <\/i><\/b><i>were presented during a R&amp;D Day in Sept. 2022<\/i>\n<\/li>\n<li>\n<b><i>\u20ac36.3 million in cash and cash equivalents<\/i><\/b><i> as of September 30, 2022<\/i>\n<\/li>\n<li>\n<i>Financial visibility until the end of 2023<\/i>\n<\/li>\n<\/ul>\n<p>STRASBOURG, France&#8211;(BUSINESS WIRE)&#8211;<a href=\"https:\/\/twitter.com\/hashtag\/HBV?src=hash\" target=\"_blank\" rel=\"noopener\">#HBV<\/a>&#8211;Regulatory News:\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20221106005032\/en\/1192643\/5\/Logo_Transgene.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20221106005032\/en\/1192643\/21\/Logo_Transgene.jpg\"><\/a><\/p>\n<p>\n<b>Transgene (Euronext Paris: TNG)<\/b><b> (Paris:TNG)<\/b><b>, a biotech company that designs and develops virus-based immunotherapies for the treatment of cancer,<\/b> today announces its business update and its financial position for the quarter ending September 30, 2022.\n<\/p>\n<p>\nPositive result from interim analysis of Phase II trial evaluating TG4001 + avelumab vs avelumab in HPV-positive anogenital cancers\n<\/p>\n<p>\nOn November 2, 2022, Transgene announced that following a prespecified interim analysis of its randomized, controlled Phase II clinical study comparing TG4001 in combination with avelumab to avelumab alone in patients with HPV16-positive anogenital tumors<b> <\/b>(<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.clinicaltrials.gov%2Fct2%2Fshow%2FNCT03260023&amp;esheet=52961453&amp;newsitemid=20221106005032&amp;lan=en-US&amp;anchor=NCT%3A+03260023&amp;index=1&amp;md5=58e76cf1db6c3c78c9e177ecab076867\" rel=\"nofollow noopener\" shape=\"rect\">NCT: 03260023<\/a>), <b>the Independent Data Monitoring Committee (IDMC) has recommended the study continues<\/b>.\n<\/p>\n<p>\n<b>Based on progression-free survival (PFS) and positive efficacy signals <\/b>observed in the interim analysis, the trial is now expected to enroll <b>a total of 120 patients<\/b> compared to the initial forecast of 150 patients. <b>Transgene anticipates the last patient to be randomized in the trial in H1 2024<\/b>. Final results will be communicated subsequently when they are available.\n<\/p>\n<p>\nFinal positive results from this trial would allow Transgene to launch a registration trial to further confirm the benefit of its therapeutic vaccine. TG4001 aims at bringing a new solution to patients who currently have very limited treatment options.\n<\/p>\n<p>\n<b>The positive interim analysis result highlights the potential of Transgene\u2019s platform of therapeutic vaccines based on the MVA viral vector.<\/b> Alongside TG4001, Transgene is also developing TG4050, an individualized, MVA-based therapeutic vaccine. TG4050 is currently being evaluated in two Phase I trials and has also delivered initial positive data, including in a randomized trial (see below).\n<\/p>\n<p>\nKey events of the third quarter 2022 and expected news flow\n<\/p>\n<p>\nDuring an R&amp;D day, held on September 27, 2022, Transgene\u2019s management team, leading clinicians and scientists from around the world, provided insights on TG4001, TG4050 and the progress of the Invir.IO\u2122 platform.\n<\/p>\n<p>\nTG4001: New positive clinical data from previous trial in HPV16+ cancer patients\n<\/p>\n<p>\n<b>In a previous single-arm Phase Ib\/II, Transgene generated strong clinical data in advanced HPV16-positive cancer patients who received TG4001 + avelumab. <\/b>The Company also identified a patient population that derived increased benefit from the treatment: metastatic patients with lesions located in organs other than the liver.\n<\/p>\n<p>\n<b>In these patients, an overall response rate (ORR) of 32%, a median PFS of 5.6 months and a median overall survival (OS) of 13.3 months were achieved in this earlier trial. These results compare favorably with checkpoint inhibitors administered alone.<\/b>\n<\/p>\n<p>\nThe treatment induced HPV16-specific T-cell responses and was associated with increased levels of immune cell infiltration in the tumors and expression of genes associated with activation of the immune system.\n<\/p>\n<p>\nThe current randomized, controlled Phase II trial was launched based on these very encouraging data.\n<\/p>\n<p>\nTG4050: New updates from the two ongoing Phase I trials confirm the strong potential of this individualized cancer vaccine\n<\/p>\n<p>\n<b>In the head and neck cancer trial, 20 of the 30 planned patients have been randomized at the end of August 2022. All 10 evaluable patients who immediately received vaccination with TG4050 (arm A) remain stable and in complete response <\/b>at the cutoff date. Out of the 10 patients of the control arm, who are monitored and did not receive the vaccine (arm B), 3 have experienced relapse.\n<\/p>\n<p>\n<b>In the ovarian cancer trial (n=5), <\/b>one patient treated after an elevation of CA-125 experienced a normalization of CA-125 without clinical progression for nine months until death from an unrelated chronic illness. Another patient was treated upon onset of radiological evidence of relapse and remained stable for 11.4 months.\n<\/p>\n<p>\n<b>To date, the vaccine has been well tolerated and no related Serious Adverse Events have been reported across the two studies.<\/b>\n<\/p>\n<p>\n<b>In the two clinical studies, enrollment has been completed.<\/b> Enrolled patients are being randomized or treated in line with study protocols. Overall, Transgene plans to treat 13 patients in the ovarian cancer trial and 30 patients in the head and neck cancer trial.\n<\/p>\n<p>\n<b>Transgene plans to communicate an update on these potentially landscape changing trials at a scientific conference in the first half of 2023.<\/b>\n<\/p>\n<p>\nSignificant progress on oncolytic viruses, including data demonstrating the potential of the Invir.IO\u2122 platform oncolytic viruses to be administered intravenously\n<\/p>\n<p>\nTransgene presented a poster on TG6002 at the ESMO congress (September 11, 2022). The Company discussed <b>positive confirmatory data from the Phase I trial evaluating TG6002 administered intravenously (IV) <\/b>in combination with oral 5-FC in patients with advanced gastrointestinal carcinomas. These updated data generated on 37 patients treated at the highest dose levels of the Phase I demonstrated that the therapy is well tolerated and confirmed the mechanism of action of TG6002 administered IV.\n<\/p>\n<p>\n<b>These findings support the potential of IV administration of Invir.IO\u2122-based oncolytic viruses, extending the use of these therapies to a broad range of solid tumors. <\/b>Additional data will be produced from the Phase I program and will be presented at a scientific congress in the first half of 2023.\n<\/p>\n<p>\n<b>In June 2022, Transgene and BioInvent released positive progress and safety data in the ongoing Phase I\/IIa trial evaluating BT-001 in patients with solid tumors.<\/b> The initial data generated in the Phase I part A demonstrated that BT-001 alone is well tolerated, with first signs of anti-tumor activity in a hard-to-treat population and confirmed the mechanism of action of BT-001 as a single agent. A clinical collaboration and supply agreement for KEYTRUDA\u00ae (pembrolizumab) was signed with MSD (Merck &amp; Co) at the end of June 2022. The Phase Ib part of the clinical trial (combination with pembrolizumab) is expected to start in the first half of 2023.\n<\/p>\n<p>\nAt the R&amp;D day, <b>Transgene introduced a novel oncolytic virus<\/b> vectorizing human IL-12 that has been designed to be administered intravenously. This Invir.IO\u2122 candidate is expected to enter clinical development in 2023.\n<\/p>\n<p>\n<b>AstraZeneca will present a poster at SITC 2022<\/b> (November 8\u201312, 2022), on a construct that was designed within the frame of its collaboration with Transgene. The preclinical data that will be presented highlight oncolysis and tumor-specific immunity induced by the oncolytic virus.\n<\/p>\n<p>\nSummary of key ongoing clinical trials\n<\/p>\n<table cellspacing=\"0\" class=\"bwwidth100 bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwwidth18 bwvertalignt bwrowaltcolor0 bwpadl0\" colspan=\"1\" rowspan=\"1\" style=\"height:60px;\">\n<p class=\"bwcellpmargin\">\n<b>TG4001<\/b>\n<\/p>\n<p class=\"bwcellpmargin\">\n<b>+ avelumab<\/b><br \/>Phase II\n<\/p>\n<p class=\"bwcellpmargin\">\nNCT03260023\n<\/p>\n<\/td>\n<td class=\"bwwidth81 bwvertalignt bwpadl0\" colspan=\"1\" rowspan=\"1\" style=\"height:60px;\">\n<p>\n<b>Targets: HPV16 E6 and E7 oncoproteins<\/b>\n<\/p>\n<p>\n<i><span class=\"bwuline\">Recurrent\/metastatic anogenital HPV16-positive \u2014 1<sup>st<\/sup> (patients ineligible for chemotherapy) and 2<sup>nd<\/sup> lines<\/span><\/i>\n<\/p>\n<p>\n\u2713 Randomized Phase II trial comparing the combination of TG4001 with avelumab versus avelumab alone\n<\/p>\n<p>\n\u2713 Active patient enrollment in Europe (France and Spain) and in the USA\n<\/p>\n<p>\n\u2713 Positive result of interim analysis, allowing trial to continue. Total number of patients to be randomized reduced from 150 to 120\n<\/p>\n<p class=\"bwcellpmargin\">\n\u27b2 <b>Last patient expected to be randomized in H1 2024<\/b>\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<table cellspacing=\"0\" class=\"bwblockalignl bwtablemarginb\">\n<tr>\n<td class=\"bwwidth18 bwvertalignt bwtopsingle bwsinglebottom bwrowaltcolor0 bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<i>myvac\u00ae<\/i>\n<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<p class=\"bwcellpmargin\">\n<b>TG4050<\/b>\n<\/p>\n<p class=\"bwcellpmargin\">\nPhase I\n<\/p>\n<p class=\"bwcellpmargin\">\nNCT03839524\n<\/p>\n<\/td>\n<td class=\"bwwidth81 bwvertalignt bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p>\n<b>Targets<\/b>: <b>tumor<\/b> <b>neoantigens<\/b>\n<\/p>\n<p>\n\u2713 Codeveloped with NEC\n<\/p>\n<p>\n\u2713 Positive initial data demonstrating the immunogenicity of the vaccine as well as first signs of clinical activity\n<\/p>\n<p class=\"bwcellpmargin\">\n\u27b2 <b>Additional data on the 2 trials expected in H1 2023<\/b>\n<\/p>\n<p>\n<i><span class=\"bwuline\">Ovarian cancer \u2014 after surgery and first-line chemotherapy<\/span><\/i>\n<\/p>\n<p>\n\u2713 Trial ongoing in the USA and in France\n<\/p>\n<p>\n\u2713 Patient enrollment completed\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwwidth18 bwvertalignt bwrowaltcolor0 bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>TG4050<\/b>\n<\/p>\n<p class=\"bwcellpmargin\">\nPhase I\n<\/p>\n<p class=\"bwcellpmargin\">\nNCT04183166\n<\/p>\n<\/td>\n<td class=\"bwwidth81 bwvertalignt bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p>\n<i><span class=\"bwuline\">HPV-negative head and neck cancer \u2014 after surgery and adjuvant therapy<\/span><\/i>\n<\/p>\n<p>\n\u2713 Trial ongoing in the UK and in France\n<\/p>\n<p class=\"bwcellpmargin\">\n\u2713 Patient enrollment completed\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<table cellspacing=\"0\" class=\"bwwidth100 bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwwidth18 bwvertalignt bwtopsingle bwsinglebottom bwpadl0 bwrowaltcolor1\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>TG6002<\/b>\n<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<p class=\"bwcellpmargin\">\nPhase I\/IIa\n<\/p>\n<p class=\"bwcellpmargin\">\nNCT03724071\n<\/p>\n<\/td>\n<td class=\"bwwidth81 bwvertalignt bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p>\n<b>Payload: FCU1 for the local production of a 5-FU chemotherapy<\/b>\n<\/p>\n<p>\n\u27b2 <b>Additional data to be presented in H1 2023<\/b>\n<\/p>\n<p>\n<i><span class=\"bwuline\">Advanced gastro-intestinal cancer (colorectal cancer for Phase II) \u2014 Intravenous (IV) administration<\/span><\/i>\n<\/p>\n<p>\n\u2713 Multicenter trial ongoing in France, Belgium and Spain\n<\/p>\n<p>\n\u2713 <b>Data confirming the potential of the IV administration presented at ESMO 2022 (Sept. 2022)<\/b>\n<\/p>\n<p class=\"bwcellpmargin\">\n\u2713 Patient enrollment completed in Phase I part\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwwidth18 bwvertalignt bwpadl0 bwrowaltcolor1\" colspan=\"1\" rowspan=\"1\" style=\"height:45px;\">\n<p class=\"bwcellpmargin\">\n<b>TG6002<\/b>\n<\/p>\n<p class=\"bwcellpmargin\">\nPhase I\/IIa\n<\/p>\n<p class=\"bwcellpmargin\">\nNCT04194034\n<\/p>\n<\/td>\n<td class=\"bwwidth81 bwvertalignt bwpadl0\" colspan=\"1\" rowspan=\"1\" style=\"height:45px;\">\n<p>\n<i><span class=\"bwuline\">Colorectal cancer with liver metastasis \u2014 Intrahepatic artery (IHA) administration<\/span><\/i>\n<\/p>\n<p>\n\u2713 Multicenter trial ongoing in the UK and in France\n<\/p>\n<p class=\"bwcellpmargin\">\n\u2713 Patient enrollment completed in Phase I part\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<table cellspacing=\"0\" class=\"bwwidth100 bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwwidth18 bwvertalignt bwpadl0 bwrowaltcolor1\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nInvir.IO\u2122\n<\/p>\n<p class=\"bwcellpmargin\">\n<b>BT-001<\/b>\n<\/p>\n<p class=\"bwcellpmargin\">\nPhase I\/IIa\n<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<p class=\"bwcellpmargin\">\nNCT04725331\n<\/p>\n<\/td>\n<td class=\"bwwidth81 bwvertalignt bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p>\n<b>Payload: anti-CTLA4 antibody and GM-CSF cytokine<\/b>\n<\/p>\n<p>\n<i><span class=\"bwuline\">Solid tumors<\/span><\/i>\n<\/p>\n<p>\n\u2713 Co-development with BioInvent\n<\/p>\n<p>\n\u2713 Collaboration agreement with MSD, supplying pembrolizumab for the trial\n<\/p>\n<p>\n\u2713 Trial ongoing in France, Belgium and approved in the USA\n<\/p>\n<p>\n\u2713 Initial data showing safety and first signs of clinical activity\n<\/p>\n<p class=\"bwcellpmargin\">\n\u27b2 <b>Start of part B of the Phase I trial in H1 2023<\/b>\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\nOperating income\n<\/p>\n<table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwvertalignb bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwpadl0\" colspan=\"2\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>Q3<\/b>\n<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwpadl0\" colspan=\"2\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>First Nine Months<\/b>\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignb bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<i>In millions of euros<\/i>\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>2022<\/b>\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>2021<\/b>\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>2022<\/b>\n<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>2021<\/b>\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwvertalignt bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<td class=\"bwvertalignt bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignr bwcellpmargin\">\n\u00a0\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nRevenue from collaborative and licensing agreements\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n0.7\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n0.2\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n3.0\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n1.6\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignb bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nGovernment financing for research expenditures\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n1.5\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n1.4\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n5.2\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n4.9\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignb bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nOther income\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwsinglebottom bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n0.1\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwsinglebottom bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n0.2\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwsinglebottom bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n0.2\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwsinglebottom bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n0.3\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignb bwpadl0\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>Operating income<\/b>\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>2.3<\/b>\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>1.8<\/b>\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>8.4<\/b>\n<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwvertalignb bwalignc\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n<b>6.8<\/b>\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n<b>During the first nine months of 2022, operating income amounted to \u20ac8.4 million compared to \u20ac6.8 million in the same period in 2021.<\/b>\n<\/p>\n<p>\n<b>Revenue from collaborative and licensing agreements amounted to \u20ac3 million in the first nine months of 2022, compared with \u20ac1.6 million in the same period in 2021.<\/b> These revenues are mainly derived from Transgene\u2019s collaboration agreement with AstraZeneca on the Invir.IO\u2122 program, whose recognized income represents \u20ac3 million as of September 30, 2022. Of this amount, \u20ac0.5 million reflects recognition of the initial payment for work done during the period and \u20ac2.5 million in respect of the supply of candidates and the performance of R&amp;D services.\n<\/p>\n<p>\n<b>During the first nine months of 2022, government financing for research expenditures, mainly in the form of a research tax credit, amounted to \u20ac5.2 million, compared to \u20ac4.9 million for the same period in 2021.<\/b>\n<\/p>\n<p>\nCash, cash equivalents and other financial assets\n<\/p>\n<p>\n<b>Cash, cash equivalents and other financial assets stood at \u20ac36.3 million as of September 30, 2022, <\/b>compared to \u20ac49.6 million as of December 31, 2021. In the first nine months of 2022, Transgene\u2019s cash burn amounted to \u20ac13.3 million (including the receipt of an $8 million payment for the first license option exercised by AstraZeneca end of 2021) compared to a cash burn of \u20ac18.7 million for the same period in 2021 (excluding capital increase).\n<\/p>\n<p>\n<b>Transgene has financial visibility until the end of 2023.<\/b>\n<\/p>\n<p>\nPost-closing event\n<\/p>\n<p>\nOn October 11, 2022, Transgene notified Tasly Holding Group and its subsidiary Tianjin Fuhade Technology Development Co. the exercise of its option under the Tasly BioPharmaceuticals Shareholder Agreement, requiring them to repurchase Transgene\u2019s stake in Tasly BioPharmaceuticals.\n<\/p>\n<p class=\"bwalignc\">\n***\n<\/p>\n<p>\n<b><i>About Transgene<\/i><\/b>\n<\/p>\n<p>\nTransgene (Euronext: TNG) is a biotechnology company focused on designing and developing targeted immunotherapies for the treatment of cancer. Transgene\u2019s programs utilize viral vector technology with the goal of indirectly or directly killing cancer cells.\n<\/p>\n<p>\nThe Company\u2019s clinical-stage programs consist of two therapeutic vaccines (TG4001 for the treatment of HPV-positive cancers, and TG4050, the first individualized therapeutic vaccine based on the <i>myvac<\/i>\u00ae platform) as well as two oncolytic viruses (TG6002 for the treatment of solid tumors, and BT-001, the first oncolytic virus based on the Invir.IO\u2122 platform).\n<\/p>\n<p>\nWith Transgene\u2019s <i>myvac<\/i>\u00ae platform, therapeutic vaccination enters the field of precision medicine with a novel immunotherapy that is fully tailored to each individual. The <i>myvac<\/i>\u00ae approach allows the generation of a virus-based immunotherapy that encodes patient-specific mutations identified and selected by Artificial Intelligence capabilities provided by its partner NEC.\n<\/p>\n<p>\nWith its proprietary platform Invir.IO\u2122, Transgene is building on its viral vector engineering expertise to design a new generation of multifunctional oncolytic viruses. Transgene has an ongoing Invir.IO\u2122 collaboration with AstraZeneca.\n<\/p>\n<p>\nAdditional information about Transgene is available at: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.transgene.fr%2F&amp;esheet=52961453&amp;newsitemid=20221106005032&amp;lan=en-US&amp;anchor=www.transgene.fr&amp;index=2&amp;md5=2487da73d4ee9f51e96eb2927bddf790\" rel=\"nofollow noopener\" shape=\"rect\">www.transgene.fr<\/a>\n<\/p>\n<p>\nFollow us on Twitter: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ftwitter.com%2Ftransgenesa&amp;esheet=52961453&amp;newsitemid=20221106005032&amp;lan=en-US&amp;anchor=%40TransgeneSA&amp;index=3&amp;md5=d8bffad7211688cfb860d79c4fbd9fcc\" rel=\"nofollow noopener\" shape=\"rect\">@TransgeneSA<\/a>\n<\/p>\n<p>\n<b><i>Disclaimer<\/i><\/b>\n<\/p>\n<p>\n<i>This press release contains forward-looking statements, which are subject to numerous risks and uncertainties, which could cause actual results to differ materially from those anticipated. The occurrence of any of these risks could have a significant negative outcome for the Company\u2019s activities, perspectives, financial situation, results, regulatory authorities\u2019 agreement with development phases, and development. The Company\u2019s ability to commercialize its products depends on but is not limited to the following factors: positive pre-clinical data may not be predictive of human clinical results, the success of clinical studies, the ability to obtain financing and\/or partnerships for product manufacturing, development and commercialization, and marketing approval by government regulatory authorities. For a discussion of risks and uncertainties which could cause the Company\u2019s actual results, financial condition, performance or achievements to differ from those contained in the forward-looking statements, please refer to the Risk Factors (\u201cFacteurs de Risque\u201d) section of the Universal Registration Document, available on the AMF website (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.amf-france.org&amp;esheet=52961453&amp;newsitemid=20221106005032&amp;lan=en-US&amp;anchor=http%3A%2F%2Fwww.amf-france.org&amp;index=4&amp;md5=eaf49df15bf94b6246f5b213939b90b8\" rel=\"nofollow noopener\" shape=\"rect\">http:\/\/www.amf-france.org<\/a>) or on Transgene\u2019s website (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.transgene.fr&amp;esheet=52961453&amp;newsitemid=20221106005032&amp;lan=en-US&amp;anchor=www.transgene.fr&amp;index=5&amp;md5=4cdb2c9604c21b900ca55e7bafc8bddd\" rel=\"nofollow noopener\" shape=\"rect\">www.transgene.fr<\/a>). Forward-looking statements speak only as of the date on which they are made, and Transgene undertakes no obligation to update these forward-looking statements, even if new information becomes available in the future.<\/i>\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\n<b>Transgene:<\/b><br \/><b>Lucie Larguier<\/b><br \/>Director Corporate Communications &amp; IR<br \/>\n<br \/>+33 (0)3 88 27 91 04<br \/>\n<br \/><a target=\"_blank\" href=\"mail&#116;&#111;&#58;&#105;&#110;&#118;&#101;&#x73;&#x74;&#x6f;&#x72;&#x72;&#x65;&#x6c;&#x61;&#x74;ions&#64;&#116;&#114;&#97;&#110;&#115;&#103;&#x65;&#x6e;&#x65;&#x2e;&#x66;&#x72;\" rel=\"nofollow noopener\" shape=\"rect\"><span>&#105;&#x6e;&#118;&#x65;s&#116;&#x6f;&#114;&#x72;e&#x6c;a&#116;&#x69;&#111;&#x6e;s&#x40;&#x74;&#114;&#x61;n&#x73;g&#101;&#x6e;&#101;&#x2e;f&#x72;<\/span><\/a>\n<\/p>\n<p>\n<b>Media: MEDiSTRAVA Consulting<\/b><br \/><b>David Dible\/Sylvie Berrebi\/George Underwood<\/b><br \/>+44 (0)203 928 6900<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;&#97;&#105;l&#x74;&#x6f;&#58;t&#x72;&#x61;&#110;sg&#x65;&#110;&#101;&#64;&#x6d;&#x65;&#100;i&#x73;&#x74;&#114;&#97;v&#x61;&#x2e;&#99;o&#x6d;\" rel=\"nofollow noopener\" shape=\"rect\">tr&#97;&#110;&#115;&#x67;&#x65;&#x6e;&#x65;&#64;m&#101;&#100;&#105;&#x73;&#x74;&#x72;&#x61;va&#46;&#99;&#111;&#x6d;<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Positive result from interim analysis and reduction of the size of the Phase II trial evaluating TG4001 + avelumab vs avelumab in HPV-positive anogenital cancers Positive clinical data on TG4050 were presented during a R&amp;D Day in Sept. 2022 \u20ac36.3 million in cash and cash equivalents as of September 30, 2022 Financial visibility until the &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["entry","post","publish","author-business","post-50530","format-standard","category-industry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Transgene Reports Business Update And Q3 2022 Financial Position - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Transgene Reports Business Update And Q3 2022 Financial Position - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Positive result from interim analysis and reduction of the size of the Phase II trial evaluating TG4001 + avelumab vs avelumab in HPV-positive anogenital cancers Positive clinical data on TG4050 were presented during a R&amp;D Day in Sept. 2022 \u20ac36.3 million in cash and cash equivalents as of September 30, 2022 Financial visibility until the ... [Read more...]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/\" \/>\n<meta property=\"og:site_name\" content=\"Pharma Trend\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-07T07:02:33+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mms.businesswire.com\/media\/20221106005032\/en\/1192643\/21\/Logo_Transgene.jpg\" \/>\n<meta name=\"author\" content=\"Business Wire\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Business Wire\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"10 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/\"},\"author\":{\"name\":\"Business Wire\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/person\\\/02d41342c7a74fa7f0032bb35ef0bb24\"},\"headline\":\"Transgene Reports Business Update And Q3 2022 Financial Position\",\"datePublished\":\"2022-11-07T07:02:33+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/\"},\"wordCount\":2037,\"publisher\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20221106005032\\\/en\\\/1192643\\\/21\\\/Logo_Transgene.jpg\",\"articleSection\":[\"Industry\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/\",\"url\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/\",\"name\":\"Transgene Reports Business Update And Q3 2022 Financial Position - Pharma Trend\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20221106005032\\\/en\\\/1192643\\\/21\\\/Logo_Transgene.jpg\",\"datePublished\":\"2022-11-07T07:02:33+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/#primaryimage\",\"url\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20221106005032\\\/en\\\/1192643\\\/21\\\/Logo_Transgene.jpg\",\"contentUrl\":\"https:\\\/\\\/mms.businesswire.com\\\/media\\\/20221106005032\\\/en\\\/1192643\\\/21\\\/Logo_Transgene.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/transgene-reports-business-update-and-q3-2022-financial-position\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Transgene Reports Business Update And Q3 2022 Financial Position\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/\",\"name\":\"Pharma Trend\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#organization\",\"name\":\"Pharma Trend\",\"url\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Pharma Trend\"},\"image\":{\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/pharma-trend.com\\\/en\\\/#\\\/schema\\\/person\\\/02d41342c7a74fa7f0032bb35ef0bb24\",\"name\":\"Business Wire\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Transgene Reports Business Update And Q3 2022 Financial Position - Pharma Trend","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/","og_locale":"en_US","og_type":"article","og_title":"Transgene Reports Business Update And Q3 2022 Financial Position - Pharma Trend","og_description":"Positive result from interim analysis and reduction of the size of the Phase II trial evaluating TG4001 + avelumab vs avelumab in HPV-positive anogenital cancers Positive clinical data on TG4050 were presented during a R&amp;D Day in Sept. 2022 \u20ac36.3 million in cash and cash equivalents as of September 30, 2022 Financial visibility until the ... [Read more...]","og_url":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/","og_site_name":"Pharma Trend","article_published_time":"2022-11-07T07:02:33+00:00","og_image":[{"url":"https:\/\/mms.businesswire.com\/media\/20221106005032\/en\/1192643\/21\/Logo_Transgene.jpg","type":"","width":"","height":""}],"author":"Business Wire","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Business Wire","Est. reading time":"10 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/#article","isPartOf":{"@id":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/"},"author":{"name":"Business Wire","@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/person\/02d41342c7a74fa7f0032bb35ef0bb24"},"headline":"Transgene Reports Business Update And Q3 2022 Financial Position","datePublished":"2022-11-07T07:02:33+00:00","mainEntityOfPage":{"@id":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/"},"wordCount":2037,"publisher":{"@id":"https:\/\/pharma-trend.com\/en\/#organization"},"image":{"@id":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/#primaryimage"},"thumbnailUrl":"https:\/\/mms.businesswire.com\/media\/20221106005032\/en\/1192643\/21\/Logo_Transgene.jpg","articleSection":["Industry"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/","url":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/","name":"Transgene Reports Business Update And Q3 2022 Financial Position - Pharma Trend","isPartOf":{"@id":"https:\/\/pharma-trend.com\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/#primaryimage"},"image":{"@id":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/#primaryimage"},"thumbnailUrl":"https:\/\/mms.businesswire.com\/media\/20221106005032\/en\/1192643\/21\/Logo_Transgene.jpg","datePublished":"2022-11-07T07:02:33+00:00","breadcrumb":{"@id":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/#primaryimage","url":"https:\/\/mms.businesswire.com\/media\/20221106005032\/en\/1192643\/21\/Logo_Transgene.jpg","contentUrl":"https:\/\/mms.businesswire.com\/media\/20221106005032\/en\/1192643\/21\/Logo_Transgene.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/pharma-trend.com\/en\/transgene-reports-business-update-and-q3-2022-financial-position\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/pharma-trend.com\/en\/"},{"@type":"ListItem","position":2,"name":"Transgene Reports Business Update And Q3 2022 Financial Position"}]},{"@type":"WebSite","@id":"https:\/\/pharma-trend.com\/en\/#website","url":"https:\/\/pharma-trend.com\/en\/","name":"Pharma Trend","description":"","publisher":{"@id":"https:\/\/pharma-trend.com\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/pharma-trend.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/pharma-trend.com\/en\/#organization","name":"Pharma Trend","url":"https:\/\/pharma-trend.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Pharma Trend"},"image":{"@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/pharma-trend.com\/en\/#\/schema\/person\/02d41342c7a74fa7f0032bb35ef0bb24","name":"Business Wire"}]}},"_links":{"self":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/posts\/50530","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/comments?post=50530"}],"version-history":[{"count":0,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/posts\/50530\/revisions"}],"wp:attachment":[{"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/media?parent=50530"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/categories?post=50530"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharma-trend.com\/en\/wp-json\/wp\/v2\/tags?post=50530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}