{"id":50546,"date":"2022-11-07T16:02:25","date_gmt":"2022-11-07T15:02:25","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/nucleai-launches-new-multiplex-imaging-spatial-analysis-solution-to-increase-reliability-and-speed-of-immunofluorescence-analysis-for-drug-discovery-and-development\/"},"modified":"2022-11-07T16:02:25","modified_gmt":"2022-11-07T15:02:25","slug":"nucleai-launches-new-multiplex-imaging-spatial-analysis-solution-to-increase-reliability-and-speed-of-immunofluorescence-analysis-for-drug-discovery-and-development","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/nucleai-launches-new-multiplex-imaging-spatial-analysis-solution-to-increase-reliability-and-speed-of-immunofluorescence-analysis-for-drug-discovery-and-development\/","title":{"rendered":"Nucleai Launches New Multiplex Imaging Spatial Analysis Solution to Increase Reliability and Speed of Immunofluorescence Analysis for Drug Discovery and Development"},"content":{"rendered":"<div>\n<p>TEL AVIV, Israel&#8211;(BUSINESS WIRE)&#8211;<a href=\"https:\/\/twitter.com\/hashtag\/Immunofluorescence?src=hash\" target=\"_blank\" rel=\"noopener\">#Immunofluorescence<\/a>&#8211;Nucleai, a leader in AI-powered spatial biology, today announced the expansion of its spatial biology platform to include a new generation of multiplex immunofluorescence (mIF) analysis that uses deep learning to establish new levels of accuracy, speed, and generalizability, further unlocking the power of mIF data for drug discovery and development. Nucleai will present new data demonstrating the power of its new mIF pipeline to correlate spatial features with patient outcomes in colorectal cancer (CRC) at the Society for Immunotherapy of Cancer (SITC) conference in Boston this week.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20221107005311\/en\/1626512\/4\/Picture1.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20221107005311\/en\/1626512\/21\/Picture1.jpg\"><\/a><\/p>\n<p>\nWhile mIF is a powerful technology for cancer research, current tools for mIF image analysis are time-consuming, manual, and not robust enough to generalize across different platforms, markers and indications. Nucleai addresses these challenges, bringing 40% improvement in accuracy compared to other solutions, while also reducing mIF analysis time-to-results from months to only weeks. Nucleai\u2019s mIF pipeline, built and trained on millions of annotations across different staining platforms, indications and markers, provides the most comprehensive mIF deep-learning based solution available on market today.\n<\/p>\n<p>\n\u201cNucleai\u2019s platform will revolutionize the reliability and speed of mIF analysis conducted by translational researchers,\u201d said Dr. Ken Bloom, Head of Pathology at Nucleai. \u201cOur deep learning approach will enable the standardization of mIF-based analysis and help establish multiplex as common practice throughout drug R&amp;D.\u201d\n<\/p>\n<p>\nNucleai\u2019s cutting-edge AI spatial models, which are optimized for multiplex assays, derive new insights from tissue biopsies, including novel drug targets, mechanisms of action, and potential biomarkers to advance the field of precision medicine. The tumor microenvironment is a highly complex ecosystem, and spatial biology can be used to unlock the important relationships and interactions. The spatial analysis that run through Nucleai\u2019s platform enables the discovery of novel tumor microenvironment cell patterns and signatures. The platform is agnostic to staining and scanning platforms and is currently available as a comprehensive service, providing fast turnaround times for large datasets of mid to high plex images.\n<\/p>\n<p>\n<b>New Data from CRC Study using Nucleai\u2019s Spatial Biology Platform<\/b>\n<\/p>\n<p>\nNucleai applied a novel end-to-end deep learning pipeline to mIF tumor-microarray images to predict outcome based on the tumor microenvironment (TME) composition. This novel deep learning pipeline for mIF analysis demonstrated high accuracy on the Nucleai platform in classifying cell types and phenotypic markers, thus enabling the identification of multiple cellular and spatial features associated with prognosis in CRC.\n<\/p>\n<p>\nCell typing model reached a 91.9% accuracy and strong performance by qualitative assessment in 97.7% of cores (&gt;75% accuracy), thereby vastly outperforming current clustering-based cell typing approaches which demonstrated 65.9% accuracy in a paper published in <i>Cell<\/i>.\n<\/p>\n<p>\n<b>Poster Presentation<\/b>\n<\/p>\n<p>\nNucleai will present the scientific poster on Friday, Nov. 11, 2022 during SITC. The poster number is 1290.\n<\/p>\n<p>\n<b>About Nucleai<\/b>\n<\/p>\n<p>\nNucleai is an AI-powered spatial biology company with a mission to transform drug development and clinical treatment decisions by unlocking the power of pathology data. Nucleai provides pharmaceutical companies, contract research organizations, and diagnostics laboratories with a state-of-the-art AI platform to improve clinical trials and clinical decision-making. For more information, please visit <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.nucleai.ai%2F&amp;esheet=52961989&amp;newsitemid=20221107005311&amp;lan=en-US&amp;anchor=www.nucleai.ai&amp;index=1&amp;md5=59d57662004ec1d7f11323f53e828b71\" rel=\"nofollow noopener\" shape=\"rect\">www.nucleai.ai<\/a>.\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\n<b>Nucleai Contact:<\/b><br \/>Jonathan Daniels<br \/>\n<br \/>VP, Head of Business Development and Strategy<br \/>\n<br \/>Email<b>: <a target=\"_blank\" href=\"&#x6d;&#x61;&#105;l&#x74;&#x6f;&#58;jo&#x6e;&#x61;&#116;h&#x61;&#x6e;&#64;&#110;u&#x63;&#x6c;&#101;a&#x69;&#x2e;&#97;&#105;\" rel=\"nofollow noopener\" shape=\"rect\">j&#111;&#x6e;&#x61;t&#104;&#97;&#x6e;&#x40;n&#117;&#x63;&#x6c;e&#97;&#105;&#x2e;&#x61;i<\/a><\/b>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>TEL AVIV, Israel&#8211;(BUSINESS WIRE)&#8211;#Immunofluorescence&#8211;Nucleai, a leader in AI-powered spatial biology, today announced the expansion of its spatial biology platform to include a new generation of multiplex immunofluorescence (mIF) analysis that uses deep learning to establish new levels of accuracy, speed, and generalizability, further unlocking the power of mIF data for drug discovery and development. Nucleai &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/nucleai-launches-new-multiplex-imaging-spatial-analysis-solution-to-increase-reliability-and-speed-of-immunofluorescence-analysis-for-drug-discovery-and-development\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-50546","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nucleai Launches New Multiplex Imaging Spatial Analysis Solution to Increase Reliability and Speed of Immunofluorescence Analysis for Drug Discovery and Development - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/nucleai-launches-new-multiplex-imaging-spatial-analysis-solution-to-increase-reliability-and-speed-of-immunofluorescence-analysis-for-drug-discovery-and-development\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nucleai Launches New Multiplex Imaging Spatial Analysis Solution to Increase Reliability and Speed of Immunofluorescence Analysis for Drug Discovery and Development - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"TEL AVIV, Israel&#8211;(BUSINESS WIRE)&#8211;#Immunofluorescence&#8211;Nucleai, a leader in AI-powered spatial biology, today announced the expansion of its spatial biology platform to include a new generation of multiplex immunofluorescence (mIF) analysis that uses deep learning to establish new levels of accuracy, speed, and generalizability, further unlocking the power of mIF data for drug discovery and development. 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