{"id":50959,"date":"2022-11-16T18:02:09","date_gmt":"2022-11-16T17:02:09","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/anagenex-appoints-pharmaceutical-rd-veteran-ryan-kruger-as-chief-scientific-officer\/"},"modified":"2022-11-16T18:02:09","modified_gmt":"2022-11-16T17:02:09","slug":"anagenex-appoints-pharmaceutical-rd-veteran-ryan-kruger-as-chief-scientific-officer","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/anagenex-appoints-pharmaceutical-rd-veteran-ryan-kruger-as-chief-scientific-officer\/","title":{"rendered":"Anagenex Appoints Pharmaceutical R&D Veteran Ryan Kruger as Chief Scientific Officer"},"content":{"rendered":"
\n

BOSTON–(BUSINESS WIRE)–#CSO<\/a>–Anagenex, a pioneering drug discovery company pairing large-scale data generation with machine learning to discover the next generation of small molecule medicines, today announced the appointment of Ryan Kruger, PhD, as Chief Scientific Officer. He brings 18 years of combined pharma and biotech experience, including 15 years at GSK, to his new role where he will be leading Anagenex\u2019s scientific and drug discovery strategy from target selection to compound development. He will also be guiding technology development to reinforce Anagenex\u2019s combined parallel biochemistry and AI platform.\n<\/p>\n

\nAt GSK, Kruger was Vice President, Head of the Cancer Epigenetics Research Unit, Oncology R&D where he was involved in the discovery and development of an industry-leading pipeline of epigenetic assets. During his time at GSK, his research unit brought forward six novel small molecule therapies from discovery, through IND filing, and on to clinical development. Kruger has also been a co-author on over 50 peer-reviewed scientific journal articles.\n<\/p>\n

\nAfter leaving GSK, Kruger served as Vice President, Head of Biology at Foghorn Therapeutics, a clinical-stage biotech. At Foghorn he led a team of biologists, bioinformaticians, and pharmacology scientists through all aspects of discovery biology and early translational medicine, from new target ID and validation through early clinical development. Kruger earned his PhD in Pharmacological Sciences at the University of Pennsylvania and completed his postdoctoral training at Harvard Medical School.\n<\/p>\n

\n\u201cThe most important thing for a technology-first drug discovery company is to know where to aim the platform for maximum impact,\u201d said Nicolas Tilmans, CEO of Anagenex. \u201cRyan has a truly exceptional understanding of the biochemistry behind disease, and his leadership will ensure that our efforts will connect to patients in need. I\u2019m overjoyed to have him join us on this journey.\u201d\n<\/p>\n

\n\u201cI\u2019m excited to join Anagenex, which has enormous potential to reshape how small molecule drugs are discovered,\u201d said Kruger. \u201cThe synergy between machine learning and DNA Encoded Libraries differentiates the company, allowing us to reliably identify bioactive compounds and validate our disease hypotheses with unprecedented speed. Anagenex has the tools to address some of the hardest targets in drug discovery. I am also incredibly encouraged by the high quality of the Anagenex team.\u201d\n<\/p>\n

\nSince beginning operations in the fall of 2020, Anagenex has built a customized parallel biochemistry platform capable of generating billions of experimentally measured datapoints. Instead of relying on simulations, Anagenex\u2019s proprietary machine learning (ML) algorithms can rely on real data and reinforce its understanding of each target by drawing from an internal database of hundreds of billions of previous measurements.\n<\/p>\n

\nAnagenex then uses the trained ML models to design up to 1 million entirely new, \u201cevolved\u201d compounds, which Anagenex then synthesizes and tests before showing the results to the initial model, further refining its accuracy. This creates a virtuous cycle of real data perfecting ML models, in turn, driving better data generation, with each cycle honing in on highly selective, potent medicines.\n<\/p>\n

\nBy applying its platform, Anagenex has already developed a strong pipeline, including several early-stage drugs for oncology and other indications.\n<\/p>\n

\nFor more information about Anagenex, go to www.anagenex.com<\/a>.\n<\/p>\n

\nAbout Anagenex<\/b>\n<\/p>\n

\nAnagenex is a pre-clinical biotechnology innovator advancing drug discovery through its small molecule directed evolution platform. The company\u2019s unique, machine learning-driven technology enables Anagenex to discover first-in-class and best-in-class small molecule medicines addressing historically intractable targets. With a team of highly experienced scientists and engineers, the company has offices in the San Francisco Bay area and Woburn, Mass. Learn more about Anagenex at www.anagenex.com<\/a> or connect on Twitter and LinkedIn.\n<\/p>\n

Contacts<\/b> <\/p>\n

\nMedia Contact<\/b>
Anthony Petrucci
\n
Bioscribe
\n
anthony@bioscribe.com<\/a>
512-581-5442\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

BOSTON–(BUSINESS WIRE)–#CSO–Anagenex, a pioneering drug discovery company pairing large-scale data generation with machine learning to discover the next generation of small molecule medicines, today announced the appointment of Ryan Kruger, PhD, as Chief Scientific Officer. 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