{"id":51973,"date":"2022-12-14T15:02:23","date_gmt":"2022-12-14T14:02:23","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/precision-biologics-successfully-completes-safety-phase-and-begins-enrollment-in-phase-2-trial-combining-neo-201-and-pembrolizumab-keytruda\/"},"modified":"2022-12-14T15:02:23","modified_gmt":"2022-12-14T14:02:23","slug":"precision-biologics-successfully-completes-safety-phase-and-begins-enrollment-in-phase-2-trial-combining-neo-201-and-pembrolizumab-keytruda","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/precision-biologics-successfully-completes-safety-phase-and-begins-enrollment-in-phase-2-trial-combining-neo-201-and-pembrolizumab-keytruda\/","title":{"rendered":"Precision Biologics Successfully Completes Safety Phase and Begins Enrollment in Phase 2 Trial Combining NEO-201 and Pembrolizumab (Keytruda)"},"content":{"rendered":"
\n

BETHESDA, Md.–(BUSINESS WIRE)–Precision Biologics, Inc. (\u201cPrecision\u201d), a clinical-stage immunotherapy and targeted oncology company, announced today the successful completion of the safety phase and the enrollment of new patients into the expansion of the Phase 2 Clinical Trial Combining Precision Biologics NEO-201 monoclonal antibody with Pembrolizumab (Keytruda).\n<\/p>\n

\nThe study is enrolling patients at the National Cancer Institute<\/a>, part of the National Institutes of Health, Bethesda, MD, with metastatic Non-Small Cell Lung Cancer (NSCLC), Head and Neck Cancers, Endometrial Cancer and Cervical Cancer, who have already been treated with checkpoint inhibitor therapy (including prior Keytruda). (https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03476681<\/a>)\n<\/p>\n

\nThis ongoing Phase 2 trial is testing to see if the combining of NEO-201 with Keytruda can reactivate the killing activity once checkpoint inhibitors no longer work alone.\n<\/p>\n

\nChristina M Annunziata, MD, PhD, Clinical Director of the Women\u2019s Malignancy Branch at the NCI has been working both preclinically and overseeing this ongoing clinical trial.\n<\/p>\n

\n\u201cIn our laboratory, we have been studying how this antibody can be used in various cancer treatments. Based on the main mechanisms of action, we have moved forward with a phase 2 clinical trial in combination with pembrolizumab,\u201d said Dr. Annunziata.\n<\/p>\n

\nNEO-201 is a unique monoclonal antibody with multiple mechanisms of action. It has been shown previously to kill cancer cells expressing its target. Additionally, it has been shown in early clinical trials to reduce immune suppressive cells that may be responsible in diminishing cancer killing activity for drugs like Keytruda.\n<\/p>\n

\nAbout Precision Biologics<\/b>\n<\/p>\n

\nFounded in 2012, Precision Biologics, Inc. is a clinical stage biotechnology corporation focused on developing therapeutic and diagnostic products for the detection and treatment of cancer. The company\u2019s antibody drug candidates and diagnostics are designed to detect and target the tumor with minimal damage to healthy cells. Precision Biologics is uniquely positioned to create innovative therapeutics through the use of proprietary cancer vaccines, several of which have demonstrated success in human trials. By marrying this platform with today\u2019s breakthrough technologies, the company is developing antibody therapeutics that could change the way we detect and treat cancer. For more information on Precision Biologics, please visit http:\/\/www.precision-biologics.com\/<\/a>.\n<\/p>\n

Contacts<\/b> <\/p>\n

\nMedia:
\n
RoseMarie Terenzio, rterenzio@kivvit.com<\/a>, c: 917-913-7226\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

BETHESDA, Md.–(BUSINESS WIRE)–Precision Biologics, Inc. (\u201cPrecision\u201d), a clinical-stage immunotherapy and targeted oncology company, announced today the successful completion of the safety phase and the enrollment of new patients into the expansion of the Phase 2 Clinical Trial Combining Precision Biologics NEO-201 monoclonal antibody with Pembrolizumab (Keytruda). The study is enrolling patients at the National Cancer … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-51973","6":"format-standard","7":"category-industry"},"yoast_head":"\nPrecision Biologics Successfully Completes Safety Phase and Begins Enrollment in Phase 2 Trial Combining NEO-201 and Pembrolizumab (Keytruda) - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/precision-biologics-successfully-completes-safety-phase-and-begins-enrollment-in-phase-2-trial-combining-neo-201-and-pembrolizumab-keytruda\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Precision Biologics Successfully Completes Safety Phase and Begins Enrollment in Phase 2 Trial Combining NEO-201 and Pembrolizumab (Keytruda) - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"BETHESDA, Md.–(BUSINESS WIRE)–Precision Biologics, Inc. 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