{"id":52144,"date":"2022-12-19T20:02:36","date_gmt":"2022-12-19T19:02:36","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/dystrophic-epidermolysis-bullosa-drug-pipeline-analysis-report-2022-comprehensive-insights-about-15-companies-and-15-pipeline-drugs-researchandmarkets-com\/"},"modified":"2022-12-19T20:02:36","modified_gmt":"2022-12-19T19:02:36","slug":"dystrophic-epidermolysis-bullosa-drug-pipeline-analysis-report-2022-comprehensive-insights-about-15-companies-and-15-pipeline-drugs-researchandmarkets-com","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/dystrophic-epidermolysis-bullosa-drug-pipeline-analysis-report-2022-comprehensive-insights-about-15-companies-and-15-pipeline-drugs-researchandmarkets-com\/","title":{"rendered":"Dystrophic Epidermolysis Bullosa Drug Pipeline Analysis Report 2022: Comprehensive Insights About 15+ Companies and 15+ Pipeline Drugs &#8211; ResearchAndMarkets.com"},"content":{"rendered":"<div>\n<p>DUBLIN&#8211;(BUSINESS WIRE)&#8211;The <a target=\"_blank\" href=\"https:\/\/www.researchandmarkets.com\/reports\/4989051\/dystrophic-epidermolysis-bullosa-pipeline?utm_source=BW&amp;utm_medium=PressRelease&amp;utm_code=w5lbt8&amp;utm_campaign=1792497+-+Dystrophic+Epidermolysis+Bullosa+Drug+Pipeline+Analysis+Report+2022%3A+Comprehensive+Insights+About+15%2B+Companies+and+15%2B+Pipeline+Drugs&amp;utm_exec=chdo54prd\" rel=\"nofollow noopener\" shape=\"rect\">&#8220;Dystrophic Epidermolysis Bullosa &#8211; Pipeline Insight, 2022&#8221;<\/a> clinical trials has been added to <strong>ResearchAndMarkets.com&#8217;s<\/strong> offering.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20221219005712\/en\/1669012\/4\/logo.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20221219005712\/en\/1669012\/21\/logo.jpg\"><\/a><\/p>\n<p>\nThis report provides comprehensive insights about 15+ companies and 15+ pipeline drugs in Dystrophic Epidermolysis Bullosa pipeline landscape.\n<\/p>\n<p>\nIt covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.\n<\/p>\n<p>\nThe assessment part of the report embraces, in depth Dystrophic Epidermolysis Bullosa commercial assessment and clinical assessment of the pipeline products under development.\n<\/p>\n<p>\nIn the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Dystrophic Epidermolysis Bullosa collaborations, licensing, mergers and acquisition, funding, designations and other product related details.\n<\/p>\n<p>\n<strong>Dystrophic Epidermolysis Bullosa Emerging Drugs Chapters<\/strong>\n<\/p>\n<p>\nThis segment of the Dystrophic Epidermolysis Bullosa report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.\n<\/p>\n<p>\n<strong>Dystrophic Epidermolysis Bullosa Emerging Drugs<\/strong>\n<\/p>\n<p>\n<strong>PTR-01: Phoenix Tissue Repair<\/strong>\n<\/p>\n<p>\nPhoenix Tissue Repair is advancing an investigational therapy known as PTR-01, a systemic recombinant collagen type VII (rC7) for the treatment of Recessive Dystrophic Epidermolysis Bullosa. rC7 is a potentially disease-modifying drug that is delivered intravenously to patients, replacing defective collagen type VII with healthy collagen at the sites where it is needed both internally and externally. Phoenix Tissue Repair acquired worldwide rights to PTR-01 from Shire Plc in 2017 and has initiated its first clinical trial.\n<\/p>\n<p>\nPreclinical studies of PTR-01 have shown that it selectively anchors in the skin and other tissues affected by an absence of collagen type VII. In four animal models of the disease, intravenous injections of PTR-01 promoted healing of DEB wounds. These experiments have shown improvements in tissue structure, disease presentation and survival, indicating a restoration of natural skin architecture.\n<\/p>\n<p>\n<strong>FCX-007: Castle Creek Biosciences<\/strong>\n<\/p>\n<p>\nD-Fi, also known as FCX-007, (dabocemagene autoficel), is being developed as an ex vivo, autologous cell-based gene therapy to address the deficiency of functional COL7 in patients with dystrophic epidermolysis bullosa (DEB). D-Fi has been clinically studied in a Phase 1\/2 clinical study (NCT02810951), which assessed 6 patients with RDEB.\n<\/p>\n<p>\nIn this study, 80% (8\/10) of treated chronic wounds demonstrated complete wound healing 12 weeks after the first injection of D-Fi, while none of the untreated wounds were healed. D-Fi was well tolerated post-administration with few reports of temporary redness or discoloration at the injection site. D-Fi is currently in Phase 3 clinical development for the localized treatment of chronic wounds in individuals with RDEB.\n<\/p>\n<p>\n<strong>Dystrophic Epidermolysis Bullosa: Therapeutic Assessment<\/strong>\n<\/p>\n<p>\nThis segment of the report provides insights about the different Dystrophic Epidermolysis Bullosa drugs segregated based on following parameters that define the scope of the report, such as:\n<\/p>\n<p>\n<strong>Major Players in Dystrophic Epidermolysis Bullosa<\/strong>\n<\/p>\n<p>\nThere are approx. 15+ key companies which are developing the therapies for Dystrophic Epidermolysis Bullosa. The companies which have their Dystrophic Epidermolysis Bullosa drug candidates in the most advanced stage, i.e. phase III include, Castle Creek Biosciences.\n<\/p>\n<p>\n<strong>Report Highlights<\/strong>\n<\/p>\n<ul>\n<li>\nA better understanding of disease pathogenesis contributing to the development of novel therapeutics for Dystrophic Epidermolysis Bullosa.\n<\/li>\n<li>\nIn the coming years, the Dystrophic Epidermolysis Bullosa market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.\n<\/li>\n<li>\nThe companies and academics that are working to assess challenges and seek opportunities that could influence Dystrophic Epidermolysis Bullosa R&amp;D. The therapies under development are focused on novel approaches to treat\/improve the disease condition.\n<\/li>\n<li>\nA detailed portfolio of major pharma players who are involved in fueling the Dystrophic Epidermolysis Bullosa treatment market. Several potential therapies for Dystrophic Epidermolysis Bullosa are under investigation. With the expected launch of these emerging therapies, it is expected that there will be a significant impact on the Dystrophic Epidermolysis Bullosa market size in the coming years.\n<\/li>\n<li>\nOur in-depth analysis of the pipeline assets (in early-stage, mid-stage and late stage of development for the treatment of Dystrophic Epidermolysis Bullosa) includes therapeutic assessment and comparative analysis. This will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities.\n<\/li>\n<\/ul>\n<p>\n<strong>Phases<\/strong>\n<\/p>\n<p>\n<strong>The report covers around 15+ products under different phases of clinical development like<\/strong>\n<\/p>\n<ul>\n<li>\nLate stage products (Phase III)\n<\/li>\n<li>\nMid-stage products (Phase II)\n<\/li>\n<li>\nEarly-stage product (Phase I) along with the details of\n<\/li>\n<li>\nPre-clinical and Discovery stage candidates\n<\/li>\n<li>\nDiscontinued &amp; Inactive candidates\n<\/li>\n<li>\nRoute of Administration\n<\/li>\n<\/ul>\n<p>\n<strong>Products have been categorized under various ROAs such as<\/strong>\n<\/p>\n<ul>\n<li>\nInhalation\n<\/li>\n<li>\nInhalation\/Intravenous\/Oral\n<\/li>\n<li>\nIntranasal\n<\/li>\n<li>\nIntravenous\n<\/li>\n<li>\nIntravenous\/ Subcutaneous\n<\/li>\n<li>\nNA\n<\/li>\n<li>\nOral\n<\/li>\n<li>\nOral\/intranasal\/subcutaneous\n<\/li>\n<li>\nParenteral\n<\/li>\n<li>\nSubcutaneous\n<\/li>\n<li>\nMolecule Type\n<\/li>\n<\/ul>\n<p>\n<strong>Products have been categorized under various Molecule types such as<\/strong>\n<\/p>\n<ul>\n<li>\nAntibody\n<\/li>\n<li>\nAntisense oligonucleotides\n<\/li>\n<li>\nImmunotherapy\n<\/li>\n<li>\nMonoclonal antibody\n<\/li>\n<li>\nPeptides\n<\/li>\n<li>\nProtein\n<\/li>\n<li>\nRecombinant protein\n<\/li>\n<li>\nSmall molecule\n<\/li>\n<li>\nStem Cell\n<\/li>\n<li>\nVaccine\n<\/li>\n<li>\nProduct Type\n<\/li>\n<\/ul>\n<p>\n<strong>Dystrophic Epidermolysis Bullosa Report Assessment<\/strong>\n<\/p>\n<ul>\n<li>\nPipeline Product Profiles\n<\/li>\n<li>\nTherapeutic Assessment\n<\/li>\n<li>\nPipeline Assessment\n<\/li>\n<li>\nInactive drugs assessment\n<\/li>\n<li>\nUnmet Needs\n<\/li>\n<\/ul>\n<p>\n<strong>Key Players<\/strong>\n<\/p>\n<ul>\n<li>\nPhoenix Tissue Repair\n<\/li>\n<li>\nCastle Creek Biosciences\n<\/li>\n<li>\nPhoenicis Therapeutics\n<\/li>\n<li>\nAegle Therapeutics\n<\/li>\n<li>\nRHEACELL GmbH &amp; Co. KG\n<\/li>\n<li>\nAnterogen Co., Ltd.\n<\/li>\n<li>\nAbeona Therapeutics, Inc\n<\/li>\n<li>\nInMed Pharmaceuticals\n<\/li>\n<li>\nBridgeBio Inc.\n<\/li>\n<li>\nEloxx Pharmaceuticals\n<\/li>\n<li>\nRelief Therapeutics\n<\/li>\n<li>\nQuoin Pharmaceuticals\n<\/li>\n<\/ul>\n<p>\n<strong>Key Products<\/strong>\n<\/p>\n<ul>\n<li>\nPTR-01\n<\/li>\n<li>\nFCX-007\n<\/li>\n<li>\nPTW-002\n<\/li>\n<li>\nAGLE 102\n<\/li>\n<li>\nallo-APZ2-EB\n<\/li>\n<li>\nALLO-ASC-SHEET\n<\/li>\n<li>\nEB-101\n<\/li>\n<li>\nINM-755\n<\/li>\n<li>\nBBP-589\n<\/li>\n<li>\nZKN-013\n<\/li>\n<li>\nNexodyn\n<\/li>\n<li>\nQRX004\n<\/li>\n<\/ul>\n<p>\nFor more information about this clinical trials report visit <a target=\"_blank\" href=\"https:\/\/www.researchandmarkets.com\/reports\/4989051\/dystrophic-epidermolysis-bullosa-pipeline?utm_source=BW&amp;utm_medium=PressRelease&amp;utm_code=w5lbt8&amp;utm_campaign=1792497+-+Dystrophic+Epidermolysis+Bullosa+Drug+Pipeline+Analysis+Report+2022%3A+Comprehensive+Insights+About+15%2B+Companies+and+15%2B+Pipeline+Drugs&amp;utm_exec=chdo54prd\" rel=\"nofollow noopener\" shape=\"rect\">https:\/\/www.researchandmarkets.com\/r\/38qtfl<\/a>\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\nResearchAndMarkets.com<br \/>\n<br \/>Laura Wood, Senior Press Manager<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;&#97;i&#x6c;&#x74;&#111;:&#x70;&#x72;&#101;s&#x73;&#64;r&#x65;&#x73;&#101;a&#x72;&#x63;&#104;a&#x6e;&#100;&#109;&#x61;&#x72;&#107;e&#x74;&#x73;&#46;c&#x6f;&#109;\" rel=\"nofollow noopener\" shape=\"rect\">&#112;&#x72;&#101;&#x73;&#115;&#x40;&#114;&#x65;s&#x65;a&#x72;c&#x68;a&#110;&#x64;&#109;&#x61;&#114;&#x6b;&#101;&#x74;&#115;&#x2e;c&#x6f;m<\/a><\/p>\n<p>For E.S.T Office Hours Call 1-917-300-0470<br \/>\n<br \/>For U.S.\/ CAN Toll Free Call 1-800-526-8630<br \/>\n<br \/>For GMT Office Hours Call +353-1-416-8900\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>DUBLIN&#8211;(BUSINESS WIRE)&#8211;The &#8220;Dystrophic Epidermolysis Bullosa &#8211; Pipeline Insight, 2022&#8221; clinical trials has been added to ResearchAndMarkets.com&#8217;s offering. This report provides comprehensive insights about 15+ companies and 15+ pipeline drugs in Dystrophic Epidermolysis Bullosa pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/dystrophic-epidermolysis-bullosa-drug-pipeline-analysis-report-2022-comprehensive-insights-about-15-companies-and-15-pipeline-drugs-researchandmarkets-com\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-52144","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dystrophic Epidermolysis Bullosa Drug Pipeline Analysis Report 2022: Comprehensive Insights About 15+ Companies and 15+ Pipeline Drugs - ResearchAndMarkets.com - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/dystrophic-epidermolysis-bullosa-drug-pipeline-analysis-report-2022-comprehensive-insights-about-15-companies-and-15-pipeline-drugs-researchandmarkets-com\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dystrophic Epidermolysis Bullosa Drug Pipeline Analysis Report 2022: Comprehensive Insights About 15+ Companies and 15+ Pipeline Drugs - ResearchAndMarkets.com - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"DUBLIN&#8211;(BUSINESS WIRE)&#8211;The &#8220;Dystrophic Epidermolysis Bullosa &#8211; Pipeline Insight, 2022&#8221; clinical trials has been added to ResearchAndMarkets.com&#8217;s offering. 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This report provides comprehensive insights about 15+ companies and 15+ pipeline drugs in Dystrophic Epidermolysis Bullosa pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product ... 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