{"id":52459,"date":"2023-01-03T08:02:33","date_gmt":"2023-01-03T07:02:33","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/new-prospective-study-evaluates-the-accuracy-of-masimo-sphb-noninvasive-and-continuous-hemoglobin-monitoring-during-elective-cesarean-section\/"},"modified":"2023-01-03T08:02:33","modified_gmt":"2023-01-03T07:02:33","slug":"new-prospective-study-evaluates-the-accuracy-of-masimo-sphb-noninvasive-and-continuous-hemoglobin-monitoring-during-elective-cesarean-section","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/new-prospective-study-evaluates-the-accuracy-of-masimo-sphb-noninvasive-and-continuous-hemoglobin-monitoring-during-elective-cesarean-section\/","title":{"rendered":"New Prospective Study Evaluates the Accuracy of Masimo SpHb\u00ae Noninvasive and Continuous Hemoglobin Monitoring During Elective Cesarean Section"},"content":{"rendered":"
\n

\nMasimo SpHb Demonstrated \u201cClinically Acceptable Accuracy\u201d of Hemoglobin Measurement, Even at Low Hemoglobin Levels<\/i>\n<\/p>\n

NEUCHATEL, Switzerland–(BUSINESS WIRE)–Masimo<\/a> (NASDAQ: MASI) today announced the findings of a prospective study published in the Egyptian Journal of Anesthesia<\/i> in which Dr. Mohamed Ibrahim Beleta and colleagues at Cairo University evaluated the accuracy of noninvasive, continuous hemoglobin monitoring with Masimo SpHb\u00ae<\/sup> on patients undergoing elective cesearan section (CS) with antepartum hemorrhage. The researchers found significant positive correlations between SpHb and invasive hemoglobin (Hb) values, and concluded, \u201cIn patients undergoing CS with antepartum hemorrhage, continuous SpHb through Masimo Pulse CO-Oximetry demonstrated clinically acceptable accuracy of Hb measurement compared with invasive Hb, even at low hemoglobin levels.\u201d1<\/sup>\n<\/p>\n

<\/a>
<\/a><\/p>\n

\nThe authors note that antepartum hemorrhage is associated with adverse maternal and neonatal outcomes and that blood transfusion is also associated with a variety of risks, but that invasive laboratory hemoglobin measurement, while a crucial factor in transfusion decisions, yields intermittent and often delayed results. The researchers thus sought to evaluate whether use of noninvasive, continuous hemoglobin monitoring might \u201cenable a more rapid detection of clinically significant blood loss, improve perioperative transfusion practices, allow patient condition to be assessed more quickly and blood management more adequately, and perhaps even reduce needless transfusions.\u201d They enrolled 60 pregnant women, aged 18-45, scheduled for elective CS under general anesthesia between April 2016 and December 2017. All subjects had antepartum hemorrhage and were candidates for blood transfusion. During the procedure, all patients were monitored as per hospital standards, and in addition, with Masimo SpHb. All blood samples (Lab Hb) were analyzed using the same Coulter laboratory analyzer to avoid variance induced by the use of multiple devices. Lab Hb and SpHb values were recorded before induction of anesthesia (baseline), before transfusion, and after transfusion. Blood transfusion was carried out when Lab Hb decreased by more than 20% from baseline.\n<\/p>\n

\nThe researchers found significant positive correlations between SpHb and invasive Hb at the three points of comparison: baseline (r = 0.946), pre-transfusion (r = 0.902), and post-transfusion (r = 0.698). Differences at those times were insignificant: p = 0.196, p = 0.092, and p = 0.570, respectively. Using Bland-Altman analysis, they found low bias and moderate limits of agreement: 0.348 g\/dL (-0.584 and 1.280) at baseline measurement, 0.314 g\/dL (-0.561 and 1.188) at pre-transfusion, and 0.348 g\/dL (-0.584 and 1.280) at post-transfusion.\n<\/p>\n

\nThe investigators concluded, \u201cContinuous SpHb Masimo Pulse CO-Oximetry shows an appropriate clinically reliable Hb calculation in comparison to Invasive Hb even in patients undergoing CS with low hemoglobin. Further studies are needed on larger sample size with multicenter collaboration. Furthermore, we recommend the assessment of this technique on patients with common morbidities, such as high cholesterol, high blood pressure, and diabetes.\u201d\n<\/p>\n

\nThe researchers also noted that \u201cSpHb evaluation has the potential for additional benefits, including patient comfort, increased safety, and decreased complexity for healthcare staff, who are not exposed to the risks of needle-stick injury and bloodspill contamination.\u201d\n<\/p>\n

\nSpHb is not intended to replace laboratory blood testing. Clinical decisions regarding red blood cell transfusions should be based on the clinician\u2019s judgment considering, among other factors, patient condition, continuous SpHb monitoring, and laboratory diagnostic tests using blood samples.\n<\/p>\n

\n@Masimo<\/a> | #Masimo\n<\/p>\n

\nAbout Masimo<\/b>\n<\/p>\n

\nMasimo (NASDAQ: MASI) is a global medical technology company that develops and produces a wide array of industry-leading monitoring technologies, including innovative measurements, sensors, patient monitors, and automation and connectivity solutions. In addition, Masimo Consumer Audio is home to eight legendary audio brands, including Bowers & Wilkins, Denon, Marantz, and Polk Audio. Our mission is to improve life, improve patient outcomes, and reduce the cost of care. Masimo SET\u00ae<\/sup> Measure-through Motion and Low Perfusion\u2122 pulse oximetry, introduced in 1995, has been shown in over 100 independent and objective studies to outperform other pulse oximetry technologies.2<\/sup> Masimo SET\u00ae<\/sup> has also been shown to help clinicians reduce severe retinopathy of prematurity in neonates,3<\/sup> improve CCHD screening in newborns,4 <\/sup>and, when used for continuous monitoring with Masimo Patient SafetyNet\u2122 in post-surgical wards, reduce rapid response team activations, ICU transfers, and costs.5-8 <\/sup>Masimo SET\u00ae<\/sup> is estimated to be used on more than 200 million patients in leading hospitals and other healthcare settings around the world,9<\/sup> and is the primary pulse oximetry at 9 of the top 10 hospitals as ranked in the 2022-23 U.S. News and World Report<\/i> Best Hospitals Honor Roll.10<\/sup> In 2005, Masimo introduced rainbow\u00ae<\/sup> Pulse CO-Oximetry technology, allowing noninvasive and continuous monitoring of blood constituents that previously could only be measured invasively, including total hemoglobin (SpHb\u00ae<\/sup>), oxygen content (SpOC\u2122), carboxyhemoglobin (SpCO\u00ae<\/sup>), methemoglobin (SpMet\u00ae<\/sup>), Pleth Variability Index (PVi\u00ae<\/sup>), RPVi\u2122 (rainbow\u00ae<\/sup> PVi), and Oxygen Reserve Index (ORi\u2122). In 2013, Masimo introduced the Root\u00ae<\/sup> Patient Monitoring and Connectivity Platform, built from the ground up to be as flexible and expandable as possible to facilitate the addition of other Masimo and third-party monitoring technologies; key Masimo additions include Next Generation SedLine\u00ae<\/sup> Brain Function Monitoring, O3\u00ae<\/sup> Regional Oximetry, and ISA\u2122 Capnography with NomoLine\u00ae<\/sup> sampling lines. Masimo\u2019s family of continuous and spot-check monitoring Pulse CO-Oximeters\u00ae<\/sup> includes devices designed for use in a variety of clinical and non-clinical scenarios, including tetherless, wearable technology, such as Radius-7\u00ae<\/sup>, Radius PPG\u00ae<\/sup>, and Radius VSM\u2122, portable devices like Rad-67\u00ae<\/sup>, fingertip pulse oximeters like MightySat\u00ae<\/sup> Rx, and devices available for use both in the hospital and at home, such as Rad-97\u00ae<\/sup>. Masimo hospital and home automation and connectivity solutions are centered around the Masimo Hospital Automation\u2122 platform, and include Iris\u00ae<\/sup> Gateway, iSirona\u2122, Patient SafetyNet, Replica\u00ae<\/sup>, Halo ION\u00ae<\/sup>, UniView\u00ae<\/sup>, UniView :60\u2122, and Masimo SafetyNet\u00ae<\/sup>. Its growing portfolio of health and wellness solutions includes Radius T\u00ba\u00ae<\/sup> and the Masimo W1\u2122 watch. Additional information about Masimo and its products may be found at www.masimo.com<\/a>. Published clinical studies on Masimo products can be found at www.masimo.com\/evidence\/featured-studies\/feature\/<\/a>.\n<\/p>\n

\nORi, RPVi, and Radius VSM have not received FDA 510(k) clearance and are not available for sale in the United States. The use of the trademark Patient SafetyNet is under license from University HealthSystem Consortium.\n<\/p>\n

\nReferences<\/b>\n<\/p>\n

    \n
  1. \nBeleta MI, Abdallah SR, Hammad YM, Hossam EMY, Ali ABE, Mohamad AA, AbdElhameed BM. Noninvasie continuous hemoglobin monitoring of blood transfusion in obstetric procedures. Egyptian J Anesth. <\/i>2022, Vol. 38, No. 1, 701-708. https:\/\/doi.org\/10.1080\/11101849.2022.2153976<\/a>.\n<\/li>\n
  2. \nPublished clinical studies on pulse oximetry and the benefits of Masimo SET\u00ae<\/sup> can be found on our website at http:\/\/www.masimo.com<\/a>. Comparative studies include independent and objective studies which are comprised of abstracts presented at scientific meetings and peer-reviewed journal articles.\n<\/li>\n
  3. \nCastillo A et al. Prevention of Retinopathy of Prematurity in Preterm Infants through Changes in Clinical Practice and SpO2<\/sub> Technology. Acta Paediatr. <\/i>2011 Feb;100(2):188-92.\n<\/li>\n
  4. \nde-Wahl Granelli A et al. Impact of pulse oximetry screening on the detection of duct dependent congenital heart disease: a Swedish prospective screening study in 39,821 newborns. BMJ. <\/i>2009;Jan 8;338.\n<\/li>\n
  5. \nTaenzer A et al. Impact of pulse oximetry surveillance on rescue events and intensive care unit transfers: a before-and-after concurrence study. Anesthesiology<\/i>. 2010:112(2):282-287.\n<\/li>\n
  6. \nTaenzer A et al. Postoperative Monitoring \u2013 The Dartmouth Experience. Anesthesia Patient Safety Foundation Newsletter<\/i>. Spring-Summer 2012.\n<\/li>\n
  7. \nMcGrath S et al. Surveillance Monitoring Management for General Care Units: Strategy, Design, and Implementation. The Joint Commission Journal on Quality and Patient Safety<\/i>. 2016 Jul;42(7):293-302.\n<\/li>\n
  8. \nMcGrath S et al. Inpatient Respiratory Arrest Associated With Sedative and Analgesic Medications: Impact of Continuous Monitoring on Patient Mortality and Severe Morbidity. J Patient Saf.<\/i> 2020 14 Mar. DOI: 10.1097\/PTS.0000000000000696.\n<\/li>\n
  9. \nEstimate: Masimo data on file.\n<\/li>\n
  10. \nhttp:\/\/health.usnews.com\/health-care\/best-hospitals\/articles\/best-hospitals-honor-roll-and-overview<\/a>.\n<\/li>\n<\/ol>\n

    \nForward-Looking Statements<\/strong>\n<\/p>\n

    \nThis press release includes forward-looking statements as defined in Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, in connection with the Private Securities Litigation Reform Act of 1995. These forward-looking statements include, among others, statements regarding the potential effectiveness of Masimo SpHb\u00ae<\/sup>. These forward-looking statements are based on current expectations about future events affecting us and are subject to risks and uncertainties, all of which are difficult to predict and many of which are beyond our control and could cause our actual results to differ materially and adversely from those expressed in our forward-looking statements as a result of various risk factors, including, but not limited to: risks related to our assumptions regarding the repeatability of clinical results; risks related to our belief that Masimo’s unique noninvasive measurement technologies, including Masimo SpHb, contribute to positive clinical outcomes and patient safety; risks that the researchers\u2019 conclusions and findings may be inaccurate; risks related to our belief that Masimo noninvasive medical breakthroughs provide cost-effective solutions and unique advantages; risks related to COVID-19; as well as other factors discussed in the “Risk Factors” section of our most recent reports filed with the Securities and Exchange Commission (“SEC”), which may be obtained for free at the SEC’s website at www.sec.gov<\/a>. Although we believe that the expectations reflected in our forward-looking statements are reasonable, we do not know whether our expectations will prove correct. All forward-looking statements included in this press release are expressly qualified in their entirety by the foregoing cautionary statements. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of today’s date. We do not undertake any obligation to update, amend or clarify these statements or the “Risk Factors” contained in our most recent reports filed with the SEC, whether as a result of new information, future events or otherwise, except as may be required under the applicable securities laws.\n<\/p>\n

    Contacts<\/b> <\/p>\n

    \nMasimo<\/i>
    Evan Lamb
    \n
    949-396-3376
    \n
    elamb@masimo.com<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    Masimo SpHb Demonstrated \u201cClinically Acceptable Accuracy\u201d of Hemoglobin Measurement, Even at Low Hemoglobin Levels NEUCHATEL, Switzerland–(BUSINESS WIRE)–Masimo (NASDAQ: MASI) today announced the findings of a prospective study published in the Egyptian Journal of Anesthesia in which Dr. Mohamed Ibrahim Beleta and colleagues at Cairo University evaluated the accuracy of noninvasive, continuous hemoglobin monitoring with Masimo … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-52459","6":"format-standard","7":"category-industry"},"yoast_head":"\nNew Prospective Study Evaluates the Accuracy of Masimo SpHb\u00ae Noninvasive and Continuous Hemoglobin Monitoring During Elective Cesarean Section - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/new-prospective-study-evaluates-the-accuracy-of-masimo-sphb-noninvasive-and-continuous-hemoglobin-monitoring-during-elective-cesarean-section\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Prospective Study Evaluates the Accuracy of Masimo SpHb\u00ae Noninvasive and Continuous Hemoglobin Monitoring During Elective Cesarean Section - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Masimo SpHb Demonstrated \u201cClinically Acceptable Accuracy\u201d of Hemoglobin Measurement, Even at Low Hemoglobin Levels NEUCHATEL, Switzerland–(BUSINESS WIRE)–Masimo (NASDAQ: MASI) today announced the findings of a prospective study published in the Egyptian Journal of Anesthesia in which Dr. Mohamed Ibrahim Beleta and colleagues at Cairo University evaluated the accuracy of noninvasive, continuous hemoglobin monitoring with Masimo ... 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