{"id":52795,"date":"2023-01-11T14:02:36","date_gmt":"2023-01-11T13:02:36","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/northstar-medical-radioisotopes-sets-new-industry-precedent-in-advancing-non-uranium-based-commercial-production-of-molybdenum-99-mo-99\/"},"modified":"2023-01-11T14:02:36","modified_gmt":"2023-01-11T13:02:36","slug":"northstar-medical-radioisotopes-sets-new-industry-precedent-in-advancing-non-uranium-based-commercial-production-of-molybdenum-99-mo-99","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/northstar-medical-radioisotopes-sets-new-industry-precedent-in-advancing-non-uranium-based-commercial-production-of-molybdenum-99-mo-99\/","title":{"rendered":"NorthStar Medical Radioisotopes Sets New Industry Precedent in Advancing Non-uranium based Commercial Production of Molybdenum-99 (Mo-99)"},"content":{"rendered":"
\n

\n\u2212 Proprietary electron accelerator technology achieves \u201ctwo beams on target\u201d milestone, validating proof of concept for large-scale U.S. Mo-99 production without the use of uranium \u2013<\/i>\n<\/p>\n

\n\u2212 NorthStar has provided the only commercial, domestic U.S. supply of Mo-99 for more than four years; electron accelerator technology will increase production capability to nearly 40% of U.S. demand \u2212<\/i>\n<\/p>\n

\n\u2212 Financial and technical support for project provided in part by the United States Department of Energy\u2019s National Nuclear Security Administration\u00a0 \u2212<\/i>\n<\/p>\n

BELOIT, Wis.–(BUSINESS WIRE)–NorthStar Medical Radioisotopes<\/a>, LLC, a global innovator in the development, production and commercialization of radiopharmaceuticals used for therapeutic applications and medical imaging, today announced it has achieved a major milestone in advancing its new technology for non-uranium based production of the critical medical radioisotope, molybdenum-99 (Mo-99). NorthStar\u2019s proprietary electron accelerator technology has successfully produced Mo-99 at its recently completed Accelerator Production facility on its Beloit, Wis. campus. The \u201ctwo beams on target\u201d accelerator approach is highly efficient, with the potential to nearly double NorthStar\u2019s commercial-scale Mo-99 capability with a single target set, and augments NorthStar\u2019s ongoing domestic Mo-99 production in collaboration with the University of Missouri Research Reactor (MURR\u00ae). Like all NorthStar processes, it uses non-uranium based technology that is independent of reliance on overseas nuclear reactors. NorthStar\u2019s technology produces far less radioactive waste than uranium-based Mo-99 production processes, which makes the NorthStar process more environmentally friendly. The U.S. Department of Energy\u2019s National Nuclear Security Administration (DOE\/NNSA) provided financial and technical support for the project as part of its program to increase U.S. production of the vital medical radioisotope Mo-99 without the use of highly enriched uranium, which is a proliferation-sensitive material. Mo-99 is the parent radioisotope of technetium-99m (Tc-99m), the most widely used diagnostic imaging radioisotope, used to inform healthcare decisions for over 40,000 U.S. patients daily.\n<\/p>\n

<\/a>
<\/a><\/p>\n

\n\u201cThis outstanding achievement of producing Mo-99 using electron accelerators marks another successful demonstration of how NorthStar continues to drive commercial-scale innovation solutions for industry to meet the needs of patients and advance clinical research,\u201d said Frank Scholz, Ph.D., President and Chief Operating Officer of NorthStar Medical Radioisotopes. \u201cOnce our newly completed Accelerator Production facility is licensed and operational, NorthStar will have sufficient total production capability to meet nearly 40% of U.S. demand for Mo-99. This is particularly important given that the historically fragile overseas Mo-99 supply chain remains fraught with shortages, as recently as this past November, underscoring the continued need for domestic, reliable, non-uranium based Mo-99 supply for the United States. We are proud that our company can lead the way in supplying our RadioGenix\u00ae System (technetium Tc 99m generator) customers with domestic Mo-99 despite these supply shortages, and we are excited by the prospect of bringing our Isotope Processing and Accelerator Production facilities online, upon completion of regulatory submissions, in mid-2023. We wish to express our deep appreciation for the great contributions in financial and technical support provided by DOE\/NNSA in helping us to achieve this goal.\u201d\n<\/p>\n

\n\u201cIn 2018, NorthStar became the first U.S. company in nearly 30 years to produce Mo-99 domestically, using a non-uranium based process of irradiating and processing molybdenum-98 targets at MURR\u00ae with neutron capture technology,\u201d said James Harvey, Ph.D., Senior Vice President and Chief Science Officer of NorthStar Medical Radioisotopes. \u201cNorthStar\u2019s Accelerator Production facility in Beloit will be the first facility in the world to produce commercial-scale Mo-99 using this new technology. It is based on irradiation of molybdenum-100 targets with two electron beams rather than the currently used single beam approach used for the production of many other isotopes. Dual electron beam accelerator production is one of the most efficient methods of making Mo-99, and can also be used to produce therapeutic radioisotopes such as copper-67 (Cu-67) and non-carrier-added actinium-225 (n.c.a. Ac-225). It enables increased Mo-99 production capability, greater scheduling flexibility and results in a benign and easily managed waste stream.\u201d\n<\/p>\n

\nAbout NorthStar Medical Radioisotopes, LLC<\/b>\n<\/p>\n

\nNorthStar Medical Radioisotopes is a commercial-stage nuclear medicine company focused on advancing patient care by providing diagnostic and therapeutic radioisotopes, novel radiopharmaceuticals and customized radiopharmaceutical development services. Its proven management team and state-of-the-art, environmentally preferable and non-uranium based technologies have made it an emerging leader at the forefront of U.S. medical radioisotope and radiopharmaceutical production. NorthStar is the sole domestic producer of molybdenum-99 (Mo-99), used to generate the standard-of-care diagnostic imaging radioisotope for assessing heart disease and cancer. It is expanding its industry-leading position in the growing area of therapeutic radioisotopes, used in targeted radiopharmaceutical therapy to treat cancer and other serious diseases, and is poised to be the first commercial-scale producer of non-carrier added (n.c.a.) actinium-225 (Ac-225) and copper-67 (Cu-67). NorthStar\u2019s Radiopharmaceutical Contract Development and Manufacturing Organization (CMDO\/CMO) services unit will provide customized service offerings and specialized radiopharmaceutical expertise to help biopharmaceutical companies rapidly advance their development and commercialization programs. For more information about NorthStar\u2019s comprehensive portfolio and patient-focused services, visit: www.northstarnm.com<\/a>.\n<\/p>\n

Contacts<\/b> <\/p>\n

\nFor NorthStar Medical Radioisotopes, LLC<\/b>
Corporate:
\n
Lisa Holst
\n
Vice President Sales and Marketing
\n
678-471-9027
\n
lholst@northstarnm.com<\/a>\n<\/p>\n

\nInvestor Relations:
\n
Paul Estrem
\n
Executive Vice President and Chief Financial Officer
\n
608-987-8318
\n
pestrem@northstarnm.com<\/a>\n<\/p>\n

\nMedia:
\n
Priscilla Harlan
\n
781-799-7917
\n
pharlan@shiningrockllc.com<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u2212 Proprietary electron accelerator technology achieves \u201ctwo beams on target\u201d milestone, validating proof of concept for large-scale U.S. Mo-99 production without the use of uranium \u2013 \u2212 NorthStar has provided the only commercial, domestic U.S. supply of Mo-99 for more than four years; electron accelerator technology will increase production capability to nearly 40% of U.S. … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-52795","6":"format-standard","7":"category-industry"},"yoast_head":"\nNorthStar Medical Radioisotopes Sets New Industry Precedent in Advancing Non-uranium based Commercial Production of Molybdenum-99 (Mo-99) - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/northstar-medical-radioisotopes-sets-new-industry-precedent-in-advancing-non-uranium-based-commercial-production-of-molybdenum-99-mo-99\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NorthStar Medical Radioisotopes Sets New Industry Precedent in Advancing Non-uranium based Commercial Production of Molybdenum-99 (Mo-99) - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"\u2212 Proprietary electron accelerator technology achieves \u201ctwo beams on target\u201d milestone, validating proof of concept for large-scale U.S. Mo-99 production without the use of uranium \u2013 \u2212 NorthStar has provided the only commercial, domestic U.S. supply of Mo-99 for more than four years; electron accelerator technology will increase production capability to nearly 40% of U.S. ... 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