{"id":52917,"date":"2023-01-13T23:02:04","date_gmt":"2023-01-13T22:02:04","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/breakthrough-crispr-technology-study-published-in-nature\/"},"modified":"2023-01-13T23:02:04","modified_gmt":"2023-01-13T22:02:04","slug":"breakthrough-crispr-technology-study-published-in-nature","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/breakthrough-crispr-technology-study-published-in-nature\/","title":{"rendered":"Breakthrough CRISPR Technology Study Published in Nature"},"content":{"rendered":"<div>\n<p class=\"bwalignc\">\n<i>Benson Hill\u2019s world-class scientists discover new mechanism for CRISPR technology that detects RNA<\/i>\n<\/p>\n<p>ST. LOUIS&#8211;(BUSINESS WIRE)&#8211;<a href=\"https:\/\/twitter.com\/search?q=%24BHIL&amp;src=ctag\" target=\"_blank\" rel=\"noopener\">$BHIL<\/a> <a href=\"https:\/\/twitter.com\/hashtag\/BHIL?src=hash\" target=\"_blank\" rel=\"noopener\">#BHIL<\/a>&#8211;A groundbreaking research study by a team that included scientists from <strong><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fbensonhill.com%2F&amp;esheet=53214538&amp;newsitemid=20230113005450&amp;lan=en-US&amp;anchor=Benson+Hill&amp;index=1&amp;md5=19b4c10295905e5daddace534ff1df78\" rel=\"nofollow noopener\" shape=\"rect\">Benson Hill<\/a><\/strong><b>,<\/b> Inc. (NYSE: BHIL, the \u201cCompany\u201d or \u201cBenson Hill\u201d), has been published this month in Nature, the world\u2019s leading multidisciplinary journal, highlighting a new mechanism for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology. The research paper, titled \u201cCas12a2 elicits abortive infection via RNA-triggered destruction of dsDNA,\u201d discusses the discovery of a new enzymatic capability for CRISPR systems, opening the possibility of using CRISPR in new applications beyond gene editing \u2013 including cancer therapeutics, programmable shaping of microbial communities, and counterselection to enhance gene editing.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20230113005450\/en\/1685905\/5\/CRISPR-Study-Share.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20230113005450\/en\/1685905\/21\/CRISPR-Study-Share.jpg\"><\/a><br \/><a href=\"https:\/\/mms.businesswire.com\/media\/20230113005450\/en\/1531350\/5\/BensonHill.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20230113005450\/en\/1531350\/21\/BensonHill.jpg\"><\/a><\/p>\n<p>\nAs part of its work to unlock the genetic diversity of plants, Benson Hill\u2019s team collaborated with members of its Scientific Advisory Board, including university <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fbensonhillwp.wpengine.com%2Fscientific-advisory-board%2F&amp;esheet=53214538&amp;newsitemid=20230113005450&amp;lan=en-US&amp;anchor=scientists&amp;index=2&amp;md5=67115e9924f7d6f3891299f39d9e219f\" rel=\"nofollow noopener\" shape=\"rect\">scientists<\/a> from the U.S. and Germany, to uncover insights and solve a complex biological problem for how CRISPR enzymes work. In doing so, they discovered the underlying biology and a new mechanism for how CRISPR nucleases, specifically Cas12a2, can function. The study concludes that Cas12a2 holds substantial potential for CRISPR technologies as a biotechnological tool.\n<\/p>\n<p>\nIn a proof-of-principle demonstration, the research team showed that a specific amino acid sequence (SuCas12a2) can be repurposed for RNA detection and potentially expand and enhance the CRISPR-based toolkit. More specifically, the study notes that RNA targeted CRISPR activity could enable programmable killing of multiple cell types.\n<\/p>\n<p>\n\u201cAt Benson Hill we recognize that it will take an entire community of innovators to solve the challenges of today. This is a great example of us partnering with the broader scientific community to better understand CRISPR technologies,\u201d said Gina Neumann, Senior Scientific Manager, Research and Development at Benson Hill. \u201cIt truly takes a diversity of thought and approaches to unlock biology. I\u2019m glad we could partner with fantastic academic collaborators to characterize this new enzymatic capability and lay a foundation for future innovative applications.\u201d\n<\/p>\n<p>\nFrom the early days of Benson Hill, the company has taken a bold approach to learning how genetic diversity can solve problems and create new technologies.\n<\/p>\n<p>\nIn November 2022 Benson Hill formally endorsed the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fgeneediting.foodintegrity.org%2Fresponsible-use-guidelines%2F&amp;esheet=53214538&amp;newsitemid=20230113005450&amp;lan=en-US&amp;anchor=Framework+for+Responsible+Use+of+Gene+Editing+in+Agriculture&amp;index=3&amp;md5=fab473cf85e5b3936002f30362c88321\" rel=\"nofollow noopener\" shape=\"rect\">Framework for Responsible Use of Gene Editing in Agriculture<\/a>. For Benson Hill, the precision of advanced breeding techniques like gene editing unlocks the opportunity to improve diverse crops and focus on benefits like taste, nutrition, and sustainability to leverage the full power of plants and deliver better food choices to consumers.\n<\/p>\n<p>\nThe full study can be found online on Nature.com and in the Jan. 4 issue. Please refer to the Nature portfolio for the full study: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fnam11.safelinks.protection.outlook.com%2F%3Furl%3Dhttps%253A%252F%252Fwww.nature.com%252Farticles%252Fs41586-022-05559-3%26data%3D05%257C01%257Ccdixon%2540bensonhill.com%257Cf49a07c3343d475b82e808dae4276331%257Cc7f40fcf92f34f52b1970dcb74039a5a%257C0%257C0%257C638073155076105560%257CUnknown%257CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%253D%257C3000%257C%257C%257C%26sdata%3D2Afdc9luXpo4DksxagfMpUVYFSxWlu6p4rwsty8owtI%253D%26reserved%3D0&amp;esheet=53214538&amp;newsitemid=20230113005450&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41586-022-05559-3&amp;index=4&amp;md5=2185382972bc3bc26c3b087b681fbc1f\" rel=\"nofollow noopener\" shape=\"rect\">https:\/\/www.nature.com\/articles\/s41586-022-05559-3<\/a>.\n<\/p>\n<p>\n<strong>About Benson Hill<\/strong>\n<\/p>\n<p>\nBenson Hill moves food forward with the CropOS<sup>\u00ae<\/sup> platform, a cutting-edge food innovation engine that combines data science and machine learning with biology and genetics. Benson Hill empowers innovators to unlock nature\u2019s genetic diversity from plant to plate, with the purpose of creating nutritious, great-tasting food and ingredient options that are both widely accessible and sustainable. More information can be found at <strong><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.bensonhill.com%2F&amp;esheet=53214538&amp;newsitemid=20230113005450&amp;lan=en-US&amp;anchor=bensonhill.com&amp;index=5&amp;md5=b8524fab5bcf7e059ee0216c4907c866\" rel=\"nofollow noopener\" shape=\"rect\">bensonhill.com<\/a><\/strong> or on Twitter at <strong><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ftwitter.com%2Fbensonhillinc&amp;esheet=53214538&amp;newsitemid=20230113005450&amp;lan=en-US&amp;anchor=%40bensonhillinc.&amp;index=6&amp;md5=6da133d0e6376d8794a5affdd5027ba0\" rel=\"nofollow noopener\" shape=\"rect\">@bensonhillinc.<\/a><\/strong>\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\n<strong>Benson Hill<\/strong><br \/>Christi Dixon<br \/>\n<br \/>636.359.0797<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;&#x61;&#105;l&#x74;&#x6f;&#58;cd&#x69;&#x78;&#111;n&#x40;&#x62;&#101;&#110;s&#x6f;&#x6e;&#104;i&#x6c;&#x6c;&#46;&#99;o&#x6d;\" rel=\"nofollow noopener\" shape=\"rect\">&#x63;&#x64;&#x69;&#x78;&#x6f;&#x6e;&#64;&#98;&#101;&#110;sonh&#x69;&#x6c;&#x6c;&#x2e;&#x63;&#x6f;&#109;<\/a><br \/><span class=\"bwuline\"><b><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.dropbox.com%2Fsh%2Fo8bt4jnet2t63zj%2FAADRgB5nqUy6AM1VixE1tphVa%3Fdl%3D0&amp;esheet=53214538&amp;newsitemid=20230113005450&amp;lan=en-US&amp;anchor=Media+Kit&amp;index=7&amp;md5=e63add8013463fc7855e0a953864e27e\" rel=\"nofollow noopener\" shape=\"rect\">Media Kit<\/a><\/b><\/span>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Benson Hill\u2019s world-class scientists discover new mechanism for CRISPR technology that detects RNA ST. LOUIS&#8211;(BUSINESS WIRE)&#8211;$BHIL #BHIL&#8211;A groundbreaking research study by a team that included scientists from Benson Hill, Inc. (NYSE: BHIL, the \u201cCompany\u201d or \u201cBenson Hill\u201d), has been published this month in Nature, the world\u2019s leading multidisciplinary journal, highlighting a new mechanism for Clustered &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/breakthrough-crispr-technology-study-published-in-nature\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-52917","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Breakthrough CRISPR Technology Study Published in Nature - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/breakthrough-crispr-technology-study-published-in-nature\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Breakthrough CRISPR Technology Study Published in Nature - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Benson Hill\u2019s world-class scientists discover new mechanism for CRISPR technology that detects RNA ST. LOUIS&#8211;(BUSINESS WIRE)&#8211;$BHIL #BHIL&#8211;A groundbreaking research study by a team that included scientists from Benson Hill, Inc. (NYSE: BHIL, the \u201cCompany\u201d or \u201cBenson Hill\u201d), has been published this month in Nature, the world\u2019s leading multidisciplinary journal, highlighting a new mechanism for Clustered ... 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