{"id":53466,"date":"2023-01-31T16:02:19","date_gmt":"2023-01-31T15:02:19","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/cagent-vascular-announces-superior-lumen-gain-greater-volumetric-blood-flow-using-serration-angioplasty-a-sub-analysis-of-the-prelude-btk-study\/"},"modified":"2023-01-31T16:02:19","modified_gmt":"2023-01-31T15:02:19","slug":"cagent-vascular-announces-superior-lumen-gain-greater-volumetric-blood-flow-using-serration-angioplasty-a-sub-analysis-of-the-prelude-btk-study","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/cagent-vascular-announces-superior-lumen-gain-greater-volumetric-blood-flow-using-serration-angioplasty-a-sub-analysis-of-the-prelude-btk-study\/","title":{"rendered":"Cagent Vascular announces superior lumen gain, greater volumetric blood flow using Serration Angioplasty: A sub-analysis of the PRELUDE BTK study"},"content":{"rendered":"
\n

WAYNE, Pa.–(BUSINESS WIRE)–#CLI<\/a>–Cagent Vascular, the exclusive developer of Serration Angioplasty (Serranator\u00ae), announced the results of a comparative sub-analysis of the PRELUDE-Below-the-Knee (BTK) study versus Plain Old Balloon Angioplasty (POBA). The study was led by Dr. Marianne Brodmann (Radcliffe Cardiology, Graz, Austria). This sub-analysis compared their PRELUDE-BTK subset to a consecutive POBA group. The Serranator-treated lesions had an average final residual stenosis of 17.2 +\/- (8.2%) versus 33.7 +\/- (15.7%) in the POBA group. This represents a 49% average improvement in final residual stenosis. In Chronic Total Occlusions (CTO), there was a 62% improvement in final residual stenosis compared to the POBA group. The average balloon inflation pressure was 5 ATM in the Serranator group versus 9 ATM in the conventional balloon angioplasty group. Additionally, Serranator-treated arteries demonstrated 2.4 times greater calculated flow improvement versus POBA. These data, analyzed by the same independent core lab, were recently published in the Journal of Endovascular Therapy.\n<\/p>\n

<\/a><\/p>\n

\nAngioplasty is the most common treatment for tibial lesions; however, it often has limitations such as inadequate lumen expansion, flow-limiting dissections, and the need for reintervention. The Serranator PTA Serration Balloon Catheter is the first and only angioplasty balloon that embeds Serration Technology into a semi-compliant balloon for treating Peripheral Artery Disease (PAD). The Serranator\u2019s mechanism of action is unique in that the serrated metal strips create multiple longitudinal lines of interrupted micro-serrations to aid arterial expansion at low inflation pressure. The Serranator is commercially available in various balloon lengths and diameters to treat both the above-the-knee and below-the-knee lesions.\n<\/p>\n

\nDr. Marianne Brodmann stated, \u201cAs an early user of Serration Angioplasty, it was meaningful to quantify through this sub-analysis what we\u2019ve experienced using the Serranator device. Dr. William Tang (Associate Dean of Research and Professor of Biomedical Engineering at UC Irvine) developed a novel model, anchored by Poiseuille’s law, from which we were able to derive the volumetric blood flow from lumen gain achieved with the Serranator compared to conventional balloon angioplasty. These results suggest an advantage for serration technology that should allow for superior wound healing and patient outcomes, while minimizing the need for stent placement.\u201d\n<\/p>\n

\nDr. Raman Sharma (Mount Sinai Medical Center, New York, NY) was an early adopter of Serration Technology, and added, \u201cWhen it comes to BTK interventions, there simply haven\u2019t been great options for physicians to treat patients, who are often in jeopardy of limb loss. In these cases, our goal is to restore sufficient blood flow to allow a patient\u2019s wound to heal, without leaving anything behind. The results from this sub-analysis study support what we have seen in our experience; the Serranator provides greater lumen gain and blood flow versus conventional technology.\u201d\n<\/p>\n

\nCarol A. Burns, President and CEO of Cagent Vascular stated, \u201cPeripheral Artery Disease (PAD), and especially Chronic Limb-Threatening Ischemia (CLTI), is well-recognized as a major contributor to poor quality of life, amputation, and even death, resulting in an enormous economic burden. The Serranator\u2019s acute results showed a meaningful improvement over conventional therapy. We believe Serration Technology is the long-awaited revolutionary advancement needed for angioplasty,\u201d Burns added.\n<\/p>\n

\nAbout Cagent Vascular<\/b>\n<\/p>\n

\nCagent Vascular\u2019s vision is to be the leader for treating atherosclerotic disease with the first and only serration balloon technology to restore blood flow. It is the second cardiovascular company formed by co-founders Carol Burns, President and CEO, Peter Schneider, MD, Vascular Surgeon, Chief Medical Advisor and Robert Giasolli, MS, Chief Technology Officer.\n<\/p>\n

\nThe information contained herein obtained from Cagent Vascular management is believed to be reliable. This does not constitute the solicitation of the purchase or sale of securities. Except for historical information contained herein, matters discussed in this document are forward-looking statements, the accuracy of which is subject to risks and uncertainties.\n<\/p>\n

\nVisit www.cagentvascular.com<\/a>\n<\/p>\n

\nThis project is supported by the Ben Franklin Technology Partners of Southeastern PA, an initiative of the Pennsylvania Department of Community and Economic Development funded by the Ben Franklin Technology Development Authority.<\/i>\n<\/p>\n

Contacts<\/b> <\/p>\n

\nLauren Pfeiffer at 610.688.2006 or info@cagentvascular.com<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

WAYNE, Pa.–(BUSINESS WIRE)–#CLI–Cagent Vascular, the exclusive developer of Serration Angioplasty (Serranator\u00ae), announced the results of a comparative sub-analysis of the PRELUDE-Below-the-Knee (BTK) study versus Plain Old Balloon Angioplasty (POBA). The study was led by Dr. Marianne Brodmann (Radcliffe Cardiology, Graz, Austria). This sub-analysis compared their PRELUDE-BTK subset to a consecutive POBA group. The Serranator-treated lesions … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-53466","6":"format-standard","7":"category-industry"},"yoast_head":"\nCagent Vascular announces superior lumen gain, greater volumetric blood flow using Serration Angioplasty: A sub-analysis of the PRELUDE BTK study - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/cagent-vascular-announces-superior-lumen-gain-greater-volumetric-blood-flow-using-serration-angioplasty-a-sub-analysis-of-the-prelude-btk-study\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cagent Vascular announces superior lumen gain, greater volumetric blood flow using Serration Angioplasty: A sub-analysis of the PRELUDE BTK study - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"WAYNE, Pa.–(BUSINESS WIRE)–#CLI–Cagent Vascular, the exclusive developer of Serration Angioplasty (Serranator\u00ae), announced the results of a comparative sub-analysis of the PRELUDE-Below-the-Knee (BTK) study versus Plain Old Balloon Angioplasty (POBA). 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