{"id":53572,"date":"2023-02-02T15:02:09","date_gmt":"2023-02-02T14:02:09","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/orserdu-now-available-from-onco360-for-the-treatment-of-postmenopausal-women-or-adult-men-with-er-positive-her2-negative-esr1-mutated-advanced-or-metastatic-breast-cancer-with-disease-prog\/"},"modified":"2023-02-02T15:02:09","modified_gmt":"2023-02-02T14:02:09","slug":"orserdu-now-available-from-onco360-for-the-treatment-of-postmenopausal-women-or-adult-men-with-er-positive-her2-negative-esr1-mutated-advanced-or-metastatic-breast-cancer-with-disease-prog","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/orserdu-now-available-from-onco360-for-the-treatment-of-postmenopausal-women-or-adult-men-with-er-positive-her2-negative-esr1-mutated-advanced-or-metastatic-breast-cancer-with-disease-prog\/","title":{"rendered":"ORSERDU\u2122 Now Available from Onco360 for the Treatment of Postmenopausal Women or Adult Men, with ER-positive, HER2-negative, ESR1-mutated Advanced or Metastatic Breast Cancer with Disease Progression Following at Least One Line of Endocrine Therapy"},"content":{"rendered":"
\n

LOUISVILLE, Ky.–(BUSINESS WIRE)–Onco360\u00ae<\/sup>, the nation\u2019s leading independent Specialty Pharmacy, has been selected by Stemline Therapeutics to be a specialty pharmacy partner for ORSERDU\u2122 (elacestrant), which is an estrogen receptor antagonist indicated for the treatment of postmenopausal women or adult men, with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.\n<\/p>\n

<\/a><\/p>\n

\n\u201cOnco360 is honored to partner with Stemline Therapeutics and become a specialty pharmacy provider for ORSERDU patients,\u201d said Benito Fernandez, Chief Commercial Officer, Onco360. \u201cBreast cancer impacts many families, including my own, continued advancement in the treatment options for patients \u2013 as offered by ORSERDU \u2013 provide us hope on improved outcomes for patients suffering from this devastating disease. We remain dedicated to supporting the highly specialized needs of patients battling previously treated, advanced ESR1-mutant, estrogen receptor-positive, HER2-negative breast cancer patients across the United States.\u201d\n<\/p>\n

\nAccording to the National Cancer Institute\u2019s Surveillance, Epidemiology, and End Results (SEER) program, it is estimated that 287,850 new cases of breast cancer will be diagnosed in 2022 in the United States with a corresponding 43,250 deaths in 2022. 68% of newly diagnosed breast cancer patients will have the hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative subtype. 6% of newly diagnosed breast cancer patients will present with metastatic disease. Additionally, dependent on tumor size and extent of lymph node involvement, 13-41% of early-stage breast will recur with distant metastatic disease. ESR1 mutations are believed to occur in up to 40% of ER-positive, HER2-negative metastatic breast cancer patients and arise due to previous exposure to standard endocrine therapies used in earlier lines of treatment. Unfortunately, the five-year overall survival (OS) for metastatic breast cancer patients is only 30%.1,2,3<\/sup>\n<\/p>\n

\nORSERDU is commercialized by Stemline Therapeutics, Inc., a Menarini Group Company. The FDA approval of ORSERDU is based on the results of the Phase III EMERALD Trial (NCT03778931) which evaluated the use of ORSERDU compared to investigator\u2019s choice of fulvestrant or an aromatase inhibitor in postmenopausal women and men with ER-positive, HER2-negative advanced or metastatic breast cancer who had disease progression on one or two prior lines of endocrine therapy, including one line containing a CDK4\/6 inhibitor. ORSERDU significantly improved progression-free survival (PFS) by 45% in the above patient population compared to investigator\u2019s choice of fulvestrant or an aromatase inhibitor.4<\/sup>\n<\/p>\n

\nAbout Onco360 Oncology Pharmacy:<\/b>\n<\/p>\n

\nOnco360 is the nation\u2019s largest independent Oncology Pharmacy and clinical support services company. Onco360 was founded in 2003 to bring together the stakeholders involved in the cancer treatment process and serve the specialized needs of oncologists, patients, hospitals, cancer centers of excellence, manufacturers, health plans, and payers. It dispenses nationally through its network of URAC-, and ACHC-accredited Oncology Pharmacies. Onco360 is headquartered in Louisville, Kentucky, and is a flagship specialty pharmacy brand of PharMerica Corporation, a leading institutional pharmacy, specialty infusion, and hospital services company servicing healthcare facilities in the United States. For more information about Onco360, please visit Onco360.com<\/a>.\n<\/p>\n

\nReferences:\n<\/p>\n\n\n\n\n\n
\n

\n1)\n<\/p>\n<\/td>\n

\n

\nFemale Breast Cancer \u2014 Cancer Stat Facts<\/a> accessed on 1\/30\/23\n<\/p>\n<\/td>\n<\/tr>\n

\n

\n2)\n<\/p>\n<\/td>\n

\n

\n20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years | NEJM<\/a> accessed on 1\/30\/23\n<\/p>\n<\/td>\n<\/tr>\n

\n

\n3)\n<\/p>\n<\/td>\n

\n

\nStemline Therapeutics, a subsidiary of Menarini Group, Receives U.S. FDA Approval for ORSERDU\u2122 (elacestrant) as the First and Only Treatment Specifically Indicated for Patients with ESR1 Mutations<\/a> accessed on 1\/30\/23\n<\/p>\n<\/td>\n<\/tr>\n

\n

\n4)\n<\/p>\n<\/td>\n

\n

\nUnited States Prescribing Information.pdf – Google Drive<\/a> accessed on 1\/30\/23\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

\n\u00a0\n<\/p>\n

Contacts<\/b> <\/p>\n

\nBenito Fernandez, Chief Commercial Officer\u00a0
\n
benito.fernandez@onco360.com<\/a>\u00a0
\n
516-640-1332\u00a0\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

LOUISVILLE, Ky.–(BUSINESS WIRE)–Onco360\u00ae, the nation\u2019s leading independent Specialty Pharmacy, has been selected by Stemline Therapeutics to be a specialty pharmacy partner for ORSERDU\u2122 (elacestrant), which is an estrogen receptor antagonist indicated for the treatment of postmenopausal women or adult men, with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-53572","6":"format-standard","7":"category-industry"},"yoast_head":"\nORSERDU\u2122 Now Available from Onco360 for the Treatment of Postmenopausal Women or Adult Men, with ER-positive, HER2-negative, ESR1-mutated Advanced or Metastatic Breast Cancer with Disease Progression Following at Least One Line of Endocrine Therapy - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/orserdu-now-available-from-onco360-for-the-treatment-of-postmenopausal-women-or-adult-men-with-er-positive-her2-negative-esr1-mutated-advanced-or-metastatic-breast-cancer-with-disease-prog\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ORSERDU\u2122 Now Available from Onco360 for the Treatment of Postmenopausal Women or Adult Men, with ER-positive, HER2-negative, ESR1-mutated Advanced or Metastatic Breast Cancer with Disease Progression Following at Least One Line of Endocrine Therapy - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"LOUISVILLE, Ky.–(BUSINESS WIRE)–Onco360\u00ae, the nation\u2019s leading independent Specialty Pharmacy, has been selected by Stemline Therapeutics to be a specialty pharmacy partner for ORSERDU\u2122 (elacestrant), which is an estrogen receptor antagonist indicated for the treatment of postmenopausal women or adult men, with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least ... 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