{"id":54399,"date":"2023-03-01T20:04:31","date_gmt":"2023-03-01T19:04:31","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/georgia-retina-participates-in-apellis-pharmaceuticals-groundbreaking-clinical-trials-for-syfovre-the-first-and-only-fda-approved-treatment-for-geographic-atrophy\/"},"modified":"2023-03-01T20:04:31","modified_gmt":"2023-03-01T19:04:31","slug":"georgia-retina-participates-in-apellis-pharmaceuticals-groundbreaking-clinical-trials-for-syfovre-the-first-and-only-fda-approved-treatment-for-geographic-atrophy","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/georgia-retina-participates-in-apellis-pharmaceuticals-groundbreaking-clinical-trials-for-syfovre-the-first-and-only-fda-approved-treatment-for-geographic-atrophy\/","title":{"rendered":"Georgia Retina Participates in Apellis Pharmaceuticals\u2019 Groundbreaking Clinical Trials for SYFOVRE, the first and only FDA-approved treatment for Geographic Atrophy"},"content":{"rendered":"
\n

\nPractice was amongst the first in the country to participate in the trials<\/i>\n<\/p>\n

\nClick here to download a photo of the SYFOVRE product<\/a>\n<\/p>\n

\nFor further details about the SYFOVRE clinical study research, click here.<\/a><\/b>\n<\/p>\n

ATLANTA–(BUSINESS WIRE)–Georgia Retina<\/a> is proud to be among the first eyecare practices throughout the country to utilize and participate in Apellis Pharmaceuticals\u2019<\/a> groundbreaking clinical trials for SYFOVRE<\/a>, the first and only FDA-approved treatment for Geographic Atrophy (GA). GA is a leading cause of blindness that impacts more than one million people in the U.S. and five million people worldwide (source 1,2).\n<\/p>\n

<\/a><\/p>\n

\nGeorgia Retina<\/a> has a long history of commitment to and participation in clinical trials to provide our patients access to new, state-of-the-art preventative, or therapeutic treatments. We partner with the National Eye Institute, some of the nation\u2019s top pharmaceutical companies, and other clinical practices to explore the causes and cures for many retinal conditions. We take special care to ensure that our study patients experience the best medical care possible.\n<\/p>\n

\n\u201cOver the last decade, we have seen many new therapies come to market for patients with wet AMD. However, those patients with dry AMD have not been so lucky… until now,\u201d said Dr. Robert Stoltz, Director of Clinical Research Studies, Georgia Retina<\/b>. \u201cIt is very exciting to now have something to offer our dry AMD patients that has been scientifically and clinically proven to slow the progression of vision loss, and maintain their quality of life. We are pleased that the results of the clinical trials demonstrated safety and effectiveness. As with any new therapy that comes to market, patients with dry AMD will need to speak with their retina specialist to know if they are a candidate for this treatment. We are so thankful to the countless number of patients who participated in the clinical trials over the years to help bring this new treatment modality to fruition.\u201d\n<\/p>\n

\nGA is an advanced form of Age-Related Macular Degeneration (AMD). It is a progressive and irreversible disease caused by the growth of lesions, which destroy the retinal cells responsible for vision. The vision loss caused by GA severely impairs independence and quality of life by making it difficult to participate in daily activities. On average, it takes only 2.5 years for GA lesions to start impacting the fovea, which is responsible for central vision (source 3).\n<\/p>\n

\n\u201cToday marks an extraordinary milestone for patients, the retina community, and Apellis. With its increasing effects over time and flexible dosing, we believe that SYFOVRE will make a meaningful difference in the lives of people with GA,\u201d said Cedric Francois, M.D., Ph.D., Co-founder and Chief Executive Officer, Apellis<\/b>. \u201cGA is a complex disease that the field has spent decades trying to address, so we are humbled and proud to bring forward the first-ever treatment. Thank you to all who helped make this moment a reality.\u201d\n<\/p>\n

\nThe approval of SYFOVRE is based on positive results from the Phase 3 OAKS and DERBY studies at 24 months across a broad and representative population of patients. SYFOVRE is approved for GA patients with or without subfoveal involvement and provides dosing flexibility for patients and physicians with a dosing regimen of every 25 to 60 days. In the OAKS and DERBY studies, SYFOVRE reduced the rate of GA lesion growth compared to sham and demonstrated increasing treatment effects over time, with the greatest benefit (up to 36% reduction in lesion growth with monthly treatment in DERBY) occurring between months 18-24.\n<\/p>\n

\n\u201cFor the first time ever, we are celebrating the approval of a treatment for GA,\u201d said Jeff Todd, President and Chief Executive Officer, Prevent Blindness<\/b>. \u201cThis is a historic and hopeful day for all GA patients and their care partners, who have been waiting for a treatment for this relentless form of vision loss.\u201d\n<\/p>\n

\nThe safety profile of SYFOVRE is well-demonstrated following ~12,000 injections. The most common adverse reactions (\u2265 5%) reported in patients receiving SYFOVRE were ocular discomfort, neovascular AMD, vitreous floaters, and conjunctival hemorrhage. SYFOVRE is expected to be available by the beginning of March through specialty distributors and specialty pharmacies nationwide. A marketing authorization application for SYFOVRE is under review by the European Medicines Agency with a decision expected in early 2024. In addition, a marketing application has been submitted to Health Canada.\n<\/p>\n

\nFor further details about the SYFOVRE clinical study research, click here.<\/a><\/b>\n<\/p>\n

\nAbout Georgia Retina:<\/b>\n<\/p>\n

\nGeorgia Retina is one of the largest retina-only medical practices in the southeastern United States, with 14 locations throughout Georgia and 18 board-certified ophthalmologists offering world-class expertise in the treatment of diseases of the retina, macula and vitreous. Our surgery center is one of the only surgery centers of its size throughout the country that provides exclusively retinal surgery. Opened to Georgia Retina doctors and patients in 2010, Georgia Retina\u2019s state-of-the-art Ambulatory Surgery Center is licensed by the state of Georgia and has achieved the highest level of accreditation \u2014 a three-year award by The American Association for Accreditation of Ambulatory Surgical Facilities, one of the nation\u2019s foremost ASC authorities. Our practice has a long history of commitment to and participation in clinical trials to provide our patients access to new, state-of-the-art preventative, or therapeutic treatments. We partner with the National Eye Institute, some of the nation\u2019s top pharmaceutical companies, and other clinical practices to explore the causes and cures for many retinal conditions. To learn more, visit: www.garetina.com<\/a>.\n<\/p>\n

\nAbout Apellis:<\/b>\n<\/p>\n

\nApellis Pharmaceuticals, Inc. is a global biopharmaceutical company that combines courageous science and compassion to develop life-changing therapies for some of the most challenging diseases patients face. We ushered in the first new class of complement medicine in 15 years and now have two approved medicines targeting C3. These include the first and only therapy for geographic atrophy, a leading cause of blindness around the world. With nearly a dozen clinical and pre-clinical programs underway, we believe we have only begun to unlock the potential of targeting C3 across many serious diseases. For more information, please visit http:\/\/apellis.com<\/a> or follow us on Twitter and LinkedIn.\n<\/p>\n

\nApellis Forward-Looking Statement:<\/b>\n<\/p>\n

\nStatements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute \u201cforward-looking statements\u201d within the meaning of The Private Securities Litigation Reform Act of 1995. These statements include, but are not limited to, statements regarding timing of the commercial availability of SYFOVRE. The words \u201canticipate,\u201d \u201cbelieve,\u201d \u201ccontinue,\u201d \u201ccould,\u201d \u201cestimate,\u201d \u201cexpect,\u201d \u201cintend,\u201d \u201cmay,\u201d \u201cplan,\u201d \u201cpotential,\u201d \u201cpredict,\u201d \u201cproject,\u201d \u201cshould,\u201d \u201ctarget,\u201d \u201cwill,\u201d \u201cwould\u201d and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including whether SYFOVRE will be commercially available when expected; whether clinical trials of SYFOVRE indicate an apparent positive effect that is greater than the actual positive effect, whether SYFOVRE will receive approval from foreign regulatory agencies for GA when expected or at all; and other factors discussed in the \u201cRisk Factors\u201d section of Apellis\u2019 Annual Report on Form 10-K with the Securities and Exchange Commission on February 28, 2022 and the risks described in other filings that Apellis may make with the Securities and Exchange Commission. Any forward-looking statements contained in this press release speak only as of the date hereof, and Apellis specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise.\n<\/p>\n

\nSources:<\/span><\/b>\n<\/p>\n

\n1<\/sup> Rudnicka AR, Jarrar Z, Wormald R, et al. Age and gender variations in age-related macular degeneration prevalence in populations of European ancestry: a meta analysis. Ophthalmology 2012;119:571\u2013580.\n<\/p>\n

\n2 <\/sup>Wong WL, Su X, Li X, et al. Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis. Lancet Glob Health 2014;2:e106\u2013116.\n<\/p>\n

\n3 <\/sup>Lindblad AS, et al, and AREDS Research Group. Arch Ophthalmol. 2009;127(9):1168-1174.\n<\/p>\n

Contacts<\/b> <\/p>\n

\nGeorgia Retina Media Contact:<\/b>
Jules Lydon
\n
(404) 383-0868
\n
julianna.lydon@eyesouthpartners.com<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Practice was amongst the first in the country to participate in the trials Click here to download a photo of the SYFOVRE product For further details about the SYFOVRE clinical study research, click here. ATLANTA–(BUSINESS WIRE)–Georgia Retina is proud to be among the first eyecare practices throughout the country to utilize and participate in Apellis … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-54399","6":"format-standard","7":"category-industry"},"yoast_head":"\nGeorgia Retina Participates in Apellis Pharmaceuticals\u2019 Groundbreaking Clinical Trials for SYFOVRE, the first and only FDA-approved treatment for Geographic Atrophy - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/georgia-retina-participates-in-apellis-pharmaceuticals-groundbreaking-clinical-trials-for-syfovre-the-first-and-only-fda-approved-treatment-for-geographic-atrophy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Georgia Retina Participates in Apellis Pharmaceuticals\u2019 Groundbreaking Clinical Trials for SYFOVRE, the first and only FDA-approved treatment for Geographic Atrophy - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Practice was amongst the first in the country to participate in the trials Click here to download a photo of the SYFOVRE product For further details about the SYFOVRE clinical study research, click here. 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ATLANTA–(BUSINESS WIRE)–Georgia Retina is proud to be among the first eyecare practices throughout the country to utilize and participate in Apellis ... 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