{"id":54713,"date":"2023-03-10T12:03:04","date_gmt":"2023-03-10T11:03:04","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/chimeric-antigen-receptor-macrophage-car-m-industry-landscape-analysis-report-2023-key-stakeholders-technologies-pipeline-partnering-and-financing-researchandmarkets-com\/"},"modified":"2023-03-10T12:03:04","modified_gmt":"2023-03-10T11:03:04","slug":"chimeric-antigen-receptor-macrophage-car-m-industry-landscape-analysis-report-2023-key-stakeholders-technologies-pipeline-partnering-and-financing-researchandmarkets-com","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/chimeric-antigen-receptor-macrophage-car-m-industry-landscape-analysis-report-2023-key-stakeholders-technologies-pipeline-partnering-and-financing-researchandmarkets-com\/","title":{"rendered":"Chimeric Antigen Receptor-Macrophage (CAR-M) Industry Landscape Analysis Report 2023: Key Stakeholders, Technologies, Pipeline, Partnering and Financing &#8211; ResearchAndMarkets.com"},"content":{"rendered":"<div>\n<p>DUBLIN&#8211;(BUSINESS WIRE)&#8211;The <a target=\"_blank\" href=\"https:\/\/www.researchandmarkets.com\/reports\/5734411\/car-m-industry-landscape-analysis-chimeric?utm_source=BW&amp;utm_medium=PressRelease&amp;utm_code=dfd3ws&amp;utm_campaign=1828607+-+Chimeric+Antigen+Receptor-Macrophage+(CAR-M)+Industry+Landscape+Analysis+Report+2023%3A+Key+Stakeholders%2C+Technologies%2C+Pipeline%2C+Partnering+and+Financing&amp;utm_exec=chdo54prd\" rel=\"nofollow noopener\" shape=\"rect\">&#8220;CAR-M Industry Landscape Analysis: Chimeric Antigen Receptor-Macrophage (CAR-M) Stakeholders, Technologies, Pipeline, Partnering and Financing&#8221;<\/a> report has been added to <strong>ResearchAndMarkets.com&#8217;s<\/strong> offering.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20230310005217\/en\/1735520\/4\/logo.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20230310005217\/en\/1735520\/21\/logo.jpg\"><\/a><\/p>\n<p>\nThis report provides you with a landscape description and analysis of chimeric antigen receptor-macrophage (CAR-M) platform technologies and stakeholders from an industry perspective as of February 2023.\n<\/p>\n<p>\nCAR-M cell therapy is an approach to overcome the limitations and obstacles of CAR T-cell and CAR natural killer (NK) cell therapy. CAR macrophages bring several unique benefits. CAR macrophages can effortlessly submerge in the cancer environment.\n<\/p>\n<p>\nAdditionally, CAR-macrophages can decrease the ratio of tumor-associated macrophages (TAMs) and switch the phenotype of TAMs. Moreover, CAR macrophages play a phagocytic role in tumor cells, facilitate antigen presentation, and augment the cytotoxicity of T cells. Finally, CAR-macrophages have less toxicity and limited circulation time than T cells.\n<\/p>\n<p>\n<strong>Research Methodology\/Scope<\/strong>\n<\/p>\n<p>\nThis report is based on information retrieved for CAR-M technology companies and partner companies regarding discovery and development collaborations, technology in- and out-licensing, and manufacturing arrangements. All information is fully referenced, either with scientific references (conference abstracts, Posters, presentations, full paper) or hyperlinks leading to the source of corporate information, such as press releases, corporate presentations, annual reports, SEC disclosures, and homepage content.\n<\/p>\n<p>\nDetails about R&amp;D strategy, collaboration and licensing agreements, acquisitions, financing rounds, and sources are described in the company profiles. For each CAR-M technology company, a profile has been elaborated providing information about the company background\/history, the financial situation, relevant technology, partnering deals, and target &amp; pipeline overview.\n<\/p>\n<p>\nA detailed description of CAR-M technologies from four companies is provided in the &#8220;CAR-M Technology Profiles&#8221; chapter. A general overview of CAR-M technologies from the other companies can be found in the respective company profile.\n<\/p>\n<p>\nEventually, this report has profiled seven CAR-M cell therapy candidates in the preclinical and clinical stages of R&amp;D. The descriptions can be found in the chapter &#8220;CAR-M Cell Therapy Candidate Profiles&#8221; in alphabetical order by the drug code.\n<\/p>\n<p>\nA detailed CAR-M Industry Landscape Analysis precedes the three profile chapters with evaluations of the companies, CAR-M technologies, and the CAR-M pipeline with targets and information about preclinical and clinical experience.\n<\/p>\n<p>\n<strong>Two main approaches for CAR-M cell therapy are:<\/strong>\n<\/p>\n<ul>\n<li>\nAutologous CAR-M cell therapy with ex vivo manufacturing or in vivo engineering of monocytes;\n<\/li>\n<li>\nAllogeneic CAR-M therapy based on induced pluripotent stem cells (iPSC).\n<\/li>\n<\/ul>\n<p>\n<strong>The report brings you up-to-date with information about and analysis of:<\/strong>\n<\/p>\n<ul>\n<li>\nApproaches for autologous and allogeneic CAR-m cell therapy;\n<\/li>\n<li>\nStakeholders in the field, i.e. technology companies, pharmaceutical partners, and investors;\n<\/li>\n<li>\nTechnologies of CAR-M construction and manufacturing;\n<\/li>\n<li>\nDelivery technologies: viral vectors; electroporation; lipid nanoparticles (LNPs)\n<\/li>\n<li>\nPipeline of autologous ex vivo\/in vivo and allogeneic CAR-M cell therapy candidates;\n<\/li>\n<li>\nTargets of CAR-M cell therapy candidates;\n<\/li>\n<li>\nProof-of-Concept with CAR-M cell therapy candidates;\n<\/li>\n<li>\nFinancing history and financial situation of CAR-M companies;\n<\/li>\n<li>\nPartnering deals (discovery and\/or development collaborations, licensing, acquisitions);\n<\/li>\n<li>\nComparative assessment.\n<\/li>\n<\/ul>\n<p>\n<strong>What will you find in the report?<\/strong>\n<\/p>\n<ul>\n<li>\nProfiles of pure-play and diversified CAR-M technology companies;\n<\/li>\n<li>\nComprehensive description and analysis of emerging autologous and allogeneic CAR-M technologies;\n<\/li>\n<li>\nPharmacologic profiles of CAR-M cell therapy candidates;\n<\/li>\n<li>\nTarget selection, pipeline analysis, and competition of CAR-M cell therapy candidates;\n<\/li>\n<li>\nDescription and analysis of financing rounds (capital raised, investors);\n<\/li>\n<li>\nEconomic terms of collaboration and licensing deals;\n<\/li>\n<li>\nSources of financing.\n<\/li>\n<\/ul>\n<p>\n<strong>Who will benefit from the report?<\/strong>\n<\/p>\n<ul>\n<li>\nVenture capital, private equity, and investment managers;\n<\/li>\n<li>\nManagers of Big Pharma venture capital firms;\n<\/li>\n<li>\nFinancial analysts;\n<\/li>\n<li>\nBusiness development and licensing (BDL) specialists;\n<\/li>\n<li>\nCEO, COO, and managing directors;\n<\/li>\n<li>\nCorporate strategy analysts and managers;\n<\/li>\n<li>\nChief Technology Officer;\n<\/li>\n<li>\nR&amp;D Portfolio, Technology, and Strategy Management;\n<\/li>\n<li>\nClinical and preclinical development specialists;\n<\/li>\n<li>\nCell therapy specialists\n<\/li>\n<\/ul>\n<p>\n<strong>Key Topics Covered:<\/strong>\n<\/p>\n<p>\n<strong>1 Executive Summary<\/strong>\n<\/p>\n<p>\n<strong>2 Introduction<\/strong>\n<\/p>\n<p>\n<strong>3 Monocyte and Macrophage Biology<\/strong>\n<\/p>\n<p>\n<strong>4 CAR-M Landscape Analysis<\/strong>\n<\/p>\n<p>\n4.1 Company Evaluations\n<\/p>\n<p>\n4.1.1 Corporate Overview\n<\/p>\n<p>\n4.1.2 Financing\n<\/p>\n<p>\n4.1.3 Partnering\n<\/p>\n<p>\n4.2 CAR-M Technology Evaluations\n<\/p>\n<p>\n4.2.1 Autologous CAR-M Technologies\n<\/p>\n<p>\n4.2.2 Allogeneic CAR-M Technologies\n<\/p>\n<p>\n4.3 Evaluation of CAR-M Pipeline, Targets, and Proof-of-Concept\n<\/p>\n<p>\n<strong>5 Company Profiles<\/strong>\n<\/p>\n<p>\n5.1 Carisma Therapeutics\n<\/p>\n<p>\n5.2 CellOrigin Biotech\n<\/p>\n<p>\n5.3 Evotec\n<\/p>\n<p>\n5.4 Fate Therapeutics\n<\/p>\n<p>\n5.5 Inceptor Bio\n<\/p>\n<p>\n5.6 Myeloid Therapeutics\n<\/p>\n<p>\n5.7 Shoreline Biosciences\n<\/p>\n<p>\n5.8 Thunder Biotech\n<\/p>\n<p>\n<strong>6 Technology Profiles<\/strong>\n<\/p>\n<p>\n6.1 ATAK CAR Monocytes\n<\/p>\n<p>\n6.2 CAR-iMAC Technology\n<\/p>\n<p>\n6.3 CAR-M Platform\n<\/p>\n<p>\n6.4 iPSC CAR Macrophage (iMAC) Technology\n<\/p>\n<p>\n<strong>7 CAR-M Cell Therapy Candidate Profiles<\/strong>\n<\/p>\n<p>\n7.1 CT-0508\n<\/p>\n<p>\n7.2 CT-0525\n<\/p>\n<p>\n7.3 CT-1119\n<\/p>\n<p>\n7.4 MT-101\n<\/p>\n<p>\n7.5 MT-102\n<\/p>\n<p>\n7.6 MT-301\n<\/p>\n<p>\n7.7 MT-302\n<\/p>\n<p>\n<strong>8 References<\/strong>\n<\/p>\n<p>\n<strong>Tables in the Text<\/strong>\n<\/p>\n<ul>\n<li>\nKey Corporate Characteristics of Companies with CAR-M Technologies\n<\/li>\n<li>\nFinancing of Companies with CAR-M Technology\n<\/li>\n<li>\nProduct Partnering of CAR-M Companies\n<\/li>\n<li>\nTechnology and Manufacturing Partnering of CAR-M Companies\n<\/li>\n<li>\nOverview of CAR-M Technologies at Carisma Therapeutics and Myeloid Therapeutics\n<\/li>\n<li>\nOverview of Research Stage iPSC &amp; CAR-iMac Technologies in Industry Development\n<\/li>\n<li>\nCAR-M Pipeline: Targets, Constructs, and R&amp;D Stage\n<\/li>\n<li>\nCAR-M Pipeline of Carisma Therapeutics\n<\/li>\n<li>\nMyeloid Therapeutics&#8217; Pipeline of Product Candidates\n<\/li>\n<\/ul>\n<p>\nFor more information about this report visit <a target=\"_blank\" href=\"https:\/\/www.researchandmarkets.com\/reports\/5734411\/car-m-industry-landscape-analysis-chimeric?utm_source=BW&amp;utm_medium=PressRelease&amp;utm_code=dfd3ws&amp;utm_campaign=1828607+-+Chimeric+Antigen+Receptor-Macrophage+(CAR-M)+Industry+Landscape+Analysis+Report+2023%3A+Key+Stakeholders%2C+Technologies%2C+Pipeline%2C+Partnering+and+Financing&amp;utm_exec=chdo54prd\" rel=\"nofollow noopener\" shape=\"rect\">https:\/\/www.researchandmarkets.com\/r\/ohi8uw<\/a>\n<\/p>\n<p>\n<strong>About ResearchAndMarkets.com<\/strong>\n<\/p>\n<p>\nResearchAndMarkets.com is the world&#8217;s leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\nResearchAndMarkets.com<br \/>\n<br \/>Laura Wood, Senior Press Manager<br \/>\n<br \/><a target=\"_blank\" href=\"m&#97;&#105;&#108;&#x74;&#x6f;&#x3a;pr&#101;&#115;&#x73;&#x40;&#x72;&#x65;se&#97;&#114;&#x63;&#x68;&#x61;&#x6e;d&#109;&#97;&#114;&#x6b;&#x65;&#x74;s&#46;&#99;&#111;&#109;\" rel=\"nofollow noopener\" shape=\"rect\">&#112;r&#x65;s&#x73;&#64;&#x72;&#101;&#x73;&#101;&#x61;&#114;c&#x68;a&#x6e;d&#x6d;&#97;&#x72;&#107;&#x65;&#116;&#x73;&#46;c&#x6f;m<\/a><br \/>For E.S.T Office Hours Call 1-917-300-0470<br \/>\n<br \/>For U.S.\/ CAN Toll Free Call 1-800-526-8630<br \/>\n<br \/>For GMT Office Hours Call +353-1-416-8900\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>DUBLIN&#8211;(BUSINESS WIRE)&#8211;The &#8220;CAR-M Industry Landscape Analysis: Chimeric Antigen Receptor-Macrophage (CAR-M) Stakeholders, Technologies, Pipeline, Partnering and Financing&#8221; report has been added to ResearchAndMarkets.com&#8217;s offering. This report provides you with a landscape description and analysis of chimeric antigen receptor-macrophage (CAR-M) platform technologies and stakeholders from an industry perspective as of February 2023. CAR-M cell therapy is an &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/chimeric-antigen-receptor-macrophage-car-m-industry-landscape-analysis-report-2023-key-stakeholders-technologies-pipeline-partnering-and-financing-researchandmarkets-com\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-54713","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Chimeric Antigen Receptor-Macrophage (CAR-M) Industry Landscape Analysis Report 2023: Key Stakeholders, Technologies, Pipeline, Partnering and Financing - ResearchAndMarkets.com - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/chimeric-antigen-receptor-macrophage-car-m-industry-landscape-analysis-report-2023-key-stakeholders-technologies-pipeline-partnering-and-financing-researchandmarkets-com\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chimeric Antigen Receptor-Macrophage (CAR-M) Industry Landscape Analysis Report 2023: Key Stakeholders, Technologies, Pipeline, Partnering and Financing - ResearchAndMarkets.com - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"DUBLIN&#8211;(BUSINESS WIRE)&#8211;The &#8220;CAR-M Industry Landscape Analysis: Chimeric Antigen Receptor-Macrophage (CAR-M) Stakeholders, Technologies, Pipeline, Partnering and Financing&#8221; report has been added to ResearchAndMarkets.com&#8217;s offering. 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This report provides you with a landscape description and analysis of chimeric antigen receptor-macrophage (CAR-M) platform technologies and stakeholders from an industry perspective as of February 2023. CAR-M cell therapy is an ... 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