{"id":55833,"date":"2023-04-14T13:07:53","date_gmt":"2023-04-14T11:07:53","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/bicycle-therapeutics-to-present-at-the-2023-aacr-annual-meeting\/"},"modified":"2023-04-14T13:07:53","modified_gmt":"2023-04-14T11:07:53","slug":"bicycle-therapeutics-to-present-at-the-2023-aacr-annual-meeting","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/bicycle-therapeutics-to-present-at-the-2023-aacr-annual-meeting\/","title":{"rendered":"Bicycle Therapeutics to Present at the 2023 AACR Annual Meeting"},"content":{"rendered":"
\n

CAMBRIDGE, England & BOSTON–(BUSINESS WIRE)–Bicycle Therapeutics plc (NASDAQ: BCYC), a biotechnology company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle<\/i>\u00ae<\/sup><\/i>) technology, today announced that the company will present four poster presentations at the 2023 American Association for Cancer Research (AACR) Annual Meeting, taking place in Orlando, FL on April 14-19, 2023.<\/p>\n

\nPoster Presentation Details:<\/b><\/p>\n

\nTitle:<\/b> Modulation of natural killer cell immune response to tumor with novel synthetic tumor-immune cell agonist, NK-TICA\u2122
\n
<\/sup>Session Title: <\/b>Immunomodulatory Agents and Interventions 1
\n
Date and Time:<\/b> Monday, April 17, 2023 at 9:00 a.m. ET
\n
Abstract Number:<\/b> 1806
\n
Speaker\/Lead Author<\/b>: Fay Dufort, Bicycle Therapeutics<\/p>\n

\nTitle:<\/b> Development of in vivo models for evaluation of NK-TICA\u2122<\/sup>, novel Bicycle\u00ae tumor-targeted immune cell agonist\u00ae<\/sup> designed to engage NK cells
\n
Session Title: <\/b>Immunomodulatory Agents and Interventions 1
\n
Date and Time:<\/b> Monday, April 17, 2023 at 9:00 a.m. ET
\n
Abstract Number:<\/b> 1826
\n
Speaker\/Lead Author:<\/b> Lukas Stanczuk, Bicycle Therapeutics<\/p>\n

\nTitle:<\/b> EphA2-dependent CD137 agonism and anti-tumor efficacy by BT7455, a Bicycle\u00ae<\/sup> tumor-targeted immune cell agonist\u00ae
\n
<\/sup>Session Title: <\/b>Immunomodulatory Agents and Interventions 2
\n
Date and Time:<\/b> Monday, April 17, 2023 at 9:00 a.m. ET
\n
Abstract Number:<\/b> 1832
\n
Speaker\/Lead Author:<\/b> Lia Luus, Bicycle Therapeutics<\/p>\n

Title:<\/b> Phase 1\/2 study of the safety, pharmacokinetics, and preliminary clinical activity of BT7480 in patients with Nectin-4 associated advanced malignancies
\n
Session Title: <\/b>Phase I and First-in-Human Clinical Trials in Progress
\n
Date and Time:<\/b> Tuesday, April 18, 2023 at 1:30 p.m. ET
\n
Abstract Number:<\/b> CT253
\n
Speaker\/Lead Author:<\/b> Thomas R. Jeffry Evans, MBBS: School of Cancer Sciences, University of Glasgow<\/p>\n

\nThe posters will be made available on the Publications section of bicycletherapeutics.com<\/a> following the presentations.<\/p>\n

\nAbout Bicycle Therapeutics<\/b><\/p>\n

\nBicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycles, for diseases that are underserved by existing therapeutics. Bicycles are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycles attractive candidates for drug development. Bicycle is evaluating BT5528, a second-generation Bicycle Toxin Conjugate (BTC\u2122) targeting EphA2; BT8009, a second-generation BTC targeting Nectin-4, a well-validated tumor antigen; and BT7480, a Bicycle TICA\u2122 targeting Nectin-4 and agonizing CD137, in company-sponsored Phase I\/II trials. In addition, BT1718, a BTC that targets MT1-MMP, is being investigated in an ongoing Phase I\/IIa clinical trial sponsored by the Cancer Research UK Centre for Drug Development. Bicycle is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, MA. For more information, visit bicycletherapeutics.com.<\/a><\/p>\n

Contacts<\/b> <\/p>\n

\nInvestors:<\/b>
David Borah, CFA
\n
SVP, Capital Markets & Corporate Communications
\n
david.borah@bicycletx.com<\/a>
617-203-8300<\/p>\n

Media:<\/b>
Argot Partners
\n
Sarah Sutton
\n
bicycle@argotpartners.com<\/a>
212-600-1902
\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

CAMBRIDGE, England & BOSTON–(BUSINESS WIRE)–Bicycle Therapeutics plc (NASDAQ: BCYC), a biotechnology company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle\u00ae) technology, today announced that the company will present four poster presentations at the 2023 American Association for Cancer Research (AACR) Annual Meeting, taking place in Orlando, FL on … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-55833","6":"format-standard","7":"category-industry"},"yoast_head":"\nBicycle Therapeutics to Present at the 2023 AACR Annual Meeting - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/bicycle-therapeutics-to-present-at-the-2023-aacr-annual-meeting\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bicycle Therapeutics to Present at the 2023 AACR Annual Meeting - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"CAMBRIDGE, England & BOSTON–(BUSINESS WIRE)–Bicycle Therapeutics plc (NASDAQ: BCYC), a biotechnology company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle\u00ae) technology, today announced that the company will present four poster presentations at the 2023 American Association for Cancer Research (AACR) Annual Meeting, taking place in Orlando, FL on ... 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