{"id":55996,"date":"2023-04-19T14:04:23","date_gmt":"2023-04-19T12:04:23","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/dxcover-presents-data-on-liquid-biopsy-platform-for-early-colorectal-cancer-detection-at-2023-american-association-for-cancer-research-aacr-annual-meeting\/"},"modified":"2023-04-19T14:04:23","modified_gmt":"2023-04-19T12:04:23","slug":"dxcover-presents-data-on-liquid-biopsy-platform-for-early-colorectal-cancer-detection-at-2023-american-association-for-cancer-research-aacr-annual-meeting","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/dxcover-presents-data-on-liquid-biopsy-platform-for-early-colorectal-cancer-detection-at-2023-american-association-for-cancer-research-aacr-annual-meeting\/","title":{"rendered":"Dxcover Presents Data on Liquid Biopsy Platform for Early Colorectal Cancer Detection at 2023 American Association for Cancer Research (AACR) Annual Meeting"},"content":{"rendered":"<div>\n<p class=\"bwalignc\">\n<i>Rapid blood test sensitive to advanced adenomas could improve patient prognosis and ultimately reduce mortality<\/i><\/p>\n<p>ORLANDO, Fla.&#8211;(BUSINESS WIRE)&#8211;<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.dxcover.com%2F&amp;esheet=53383371&amp;newsitemid=20230419005178&amp;lan=en-US&amp;anchor=Dxcover+Limited&amp;index=1&amp;md5=b8c0a2926d7d1da182cc7ac71475282e\" rel=\"nofollow noopener\" shape=\"rect\">Dxcover Limited<\/a>, a clinical-stage diagnostics company developing spectroscopic liquid biopsy technology for early detection of multiple cancers, today presented new data in a presentation titled \u201cEarly Detection and Molecular Markers of Prevention\u201d on the detection of colorectal cancer (CRC) using the company\u2019s liquid biopsy platform at the 2023 American Association for Cancer Research (AACR) Annual Meeting in Orlando, Florida from April 14-19.<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20230419005178\/en\/1474955\/5\/Dxcover_Logo_Dark_RGB_v1_GF_Full.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20230419005178\/en\/1474955\/21\/Dxcover_Logo_Dark_RGB_v1_GF_Full.jpg\"><\/a><\/p>\n<p>\nCo-founder and CTO Matthew Baker, PhD, outlined data from a preclinical study evaluating the Dxcover\u00ae Cancer Liquid Biopsy platform\u2019s capabilities to detect advanced adenomas and early cases of colorectal cancer. CRC is the third most common cancer among both men and women, which would greatly benefit from earlier detection due to decreased survival rates as the cancer progresses. On average, the survival rate after diagnosis for CRC decreases from 91% in early-stage CRC to as low as 15% for stage IV.<\/p>\n<p>\nDxcover analyzed a retrospective cohort of 296 samples comprised of 100 CRC, 99 advanced adenomas (AA) removed by surgical resection and 97 colonoscopy screening controls. The classifier from the discovery reported the ability to detect 59% of advanced adenomas and 83% of Stage 1 CRC at a specificity of 90% which surpasses the targets set by the Centers for Medicare and Medicaid Services (CMS) for coverage of CRC tests.<\/p>\n<p>\n\u201cEarly detection, and the detection of pre-cancerous adenomas, is critical to advancing lifespan for those impacted by potentially devastating diseases like colorectal cancer. This data shows that Dxcover\u2019s unique approach at detecting biomarkers beyond tumor DNA allows our technology to detect sooner, faster and with precision to ensure patients receive the treatment they need, when it has the most potential to impact outcomes,\u201d said Prof. Baker.<\/p>\n<p>\nThe Dxcover Cancer Liquid Biopsy test uses Fourier transform infrared (FTIR) spectroscopy and machine learning algorithms to build a classifier of the resultant spectral profiles to detect cancer and can be fine-tuned to maximize either sensitivity or specificity depending on the requirements of specific international healthcare systems.<\/p>\n<p>\n<b>About Dxcover Limited<br \/>\n<br \/><\/b>Dxcover is a clinical stage liquid biopsy company developing tests for the early detection of multiple cancers, when treatment has a better chance to impact outcomes. The company has pioneered the early detection and identification of cancer by infrared spectroscopy of circulating pan-omic biomarkers. The company has generated compelling clinical data with high accuracy detection of Stage I and Stage II cancers. Dxcover is based in Scotland, United Kingdom and is expanding its network in Europe and the USA.<\/p>\n<p>\nFor further information go to <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.dxcover.com%2Fscience&amp;esheet=53383371&amp;newsitemid=20230419005178&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.dxcover.com%2Fscience&amp;index=2&amp;md5=603051f8cfb72c79cf9bf7a66c6fac0b\" rel=\"nofollow noopener\" shape=\"rect\">https:\/\/www.dxcover.com\/science<\/a><\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\n<b>Media:<\/b><br \/><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fmacdougall.bio%2F&amp;esheet=53383371&amp;newsitemid=20230419005178&amp;lan=en-US&amp;anchor=MacDougall+Advisors&amp;index=3&amp;md5=2cf89a1171376020d2e19f0325071649\" rel=\"nofollow noopener\" shape=\"rect\">MacDougall Advisors<\/a><br \/>Tara Mulloy<br \/>\n<br \/><a target=\"_blank\" href=\"&#109;a&#x69;l&#x74;o&#x3a;t&#x6d;&#117;&#x6c;&#108;&#x6f;&#121;&#x40;&#109;a&#99;d&#x6f;u&#x67;a&#x6c;&#108;&#x2e;&#98;&#x69;&#111;\" rel=\"nofollow noopener\" shape=\"rect\">&#x74;&#x6d;&#117;&#108;l&#x6f;&#x79;&#x40;&#109;&#97;c&#x64;&#x6f;&#x75;&#103;&#97;l&#x6c;&#x2e;&#x62;&#105;&#111;<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Rapid blood test sensitive to advanced adenomas could improve patient prognosis and ultimately reduce mortality ORLANDO, Fla.&#8211;(BUSINESS WIRE)&#8211;Dxcover Limited, a clinical-stage diagnostics company developing spectroscopic liquid biopsy technology for early detection of multiple cancers, today presented new data in a presentation titled \u201cEarly Detection and Molecular Markers of Prevention\u201d on the detection of colorectal cancer &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/dxcover-presents-data-on-liquid-biopsy-platform-for-early-colorectal-cancer-detection-at-2023-american-association-for-cancer-research-aacr-annual-meeting\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-55996","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dxcover Presents Data on Liquid Biopsy Platform for Early Colorectal Cancer Detection at 2023 American Association for Cancer Research (AACR) Annual Meeting - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/dxcover-presents-data-on-liquid-biopsy-platform-for-early-colorectal-cancer-detection-at-2023-american-association-for-cancer-research-aacr-annual-meeting\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dxcover Presents Data on Liquid Biopsy Platform for Early Colorectal Cancer Detection at 2023 American Association for Cancer Research (AACR) Annual Meeting - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Rapid blood test sensitive to advanced adenomas could improve patient prognosis and ultimately reduce mortality ORLANDO, Fla.&#8211;(BUSINESS WIRE)&#8211;Dxcover Limited, a clinical-stage diagnostics company developing spectroscopic liquid biopsy technology for early detection of multiple cancers, today presented new data in a presentation titled \u201cEarly Detection and Molecular Markers of Prevention\u201d on the detection of colorectal cancer ... 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