{"id":60489,"date":"2024-12-13T04:02:25","date_gmt":"2024-12-13T03:02:25","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/beigene-announces-global-licensing-agreement-for-mat2a-inhibitor\/"},"modified":"2024-12-13T04:02:25","modified_gmt":"2024-12-13T03:02:25","slug":"beigene-announces-global-licensing-agreement-for-mat2a-inhibitor","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/beigene-announces-global-licensing-agreement-for-mat2a-inhibitor\/","title":{"rendered":"BeiGene Announces Global Licensing Agreement for MAT2A Inhibitor"},"content":{"rendered":"
\n

SAN MATEO, Calif.–(BUSINESS WIRE)–$BGNE<\/a> #BeiGene<\/a>—BeiGene, Ltd.<\/a> (NASDAQ: BGNE; HKEX: 06160; SSE: 688235), a global oncology company that intends to change its name to BeOne Medicines Ltd., today announced it has entered into a global licensing agreement with CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (\u201cCSPC\u201d) for SYH2039, a novel methionine adenosyltransferase 2A (MAT2A)-inhibitor being explored for solid tumors.<\/p>\n

<\/a>
<\/a><\/p>\n

\nSYH2039 targets solid tumors that have a mutation called MTAP deletion, which is estimated to be present in approximately 15 percent of all cancer types with the most common including glioblastoma, pancreatic cancer and non-small cell lung cancer.<\/p>\n

\n\u201cWith one of the most dynamic solid tumor portfolios in the industry, we are continually assessing opportunities that align with our strategic focus and address significant unmet needs for patients. This MAT2A inhibitor is a valuable addition to our solid tumor pipeline, and we\u2019re eager to explore its potential, particularly in combination with our internally developed PRMT5 inhibitor, BGB-58067. Together, these assets hold promise for advancing treatment across a range of solid tumors,\u201d said Lai Wang, Ph.D., Global Head of R&D at BeiGene.<\/p>\n

\nBGB-58067, which is on track to enter the clinic before the end of the year, is designed to avoid on-target hematological toxicity seen with first-generation PRMT5 inhibitors. It has best-in-class potential with high potency, selectivity, and brain penetrability.<\/p>\n

\nUnder the terms of the agreement, BeiGene has an exclusive license to develop, manufacture and commercialize SYH2039 worldwide. CSPC will receive upfront and time-based payments totaling $150 million and will be eligible for payments upon the achievement of certain development and commercial milestones and tiered royalties.<\/p>\n

\nBeiGene is focused on growing its leadership in solid tumors with its PD-1 inhibitor TEVIMBRA\u00ae <\/sup><\/i>(tislelizumab) and by advancing potential best-in-class assets for lung, breast and gastrointestinal cancers, including several differentiated antibody drug conjugates, multi-specific antibodies, targeted protein degraders, and small molecule inhibitors. The Company recently announced its intent to change its name to BeOne, reaffirming its commitment to develop innovative medicines to eliminate cancer by partnering with the global community to serve as many patients as possible.<\/p>\n

\nAbout BeiGene<\/b><\/p>\n

\nBeiGene, which plans to change its name to BeOne Medicines, is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of nearly 11,000 colleagues spans five continents. To learn more about BeiGene, please visit www.beigene.com<\/a> and follow us on LinkedIn<\/a>, X<\/a> (formerly known as Twitter), Facebook<\/a> and Instagram<\/a>.<\/p>\n

\nForward-Looking Statements<\/b><\/p>\n

\nThis press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and other federal securities laws, including statements regarding the value and future potential of the MAT2A inhibitor; the ability of BeiGene\u2019s assets to advance treatment across solid tumors and its future leadership in solid tumors; the projected date at which BGB-58067 will enter the clinic and its future success; and BeiGene\u2019s plans, commitments, aspirations and goals under the caption \u201cAbout BeiGene.\u201d Actual results may differ materially from those indicated in the forward-looking statements as a result of various important factors, including BeiGene\u2019s ability to demonstrate the efficacy and safety of its drug candidates; the clinical results for its drug candidates, which may not support further development or marketing approval; actions of regulatory agencies, which may affect the initiation, timing and progress of clinical trials and marketing approval; BeiGene\u2019s ability to achieve commercial success for its marketed medicines and drug candidates, if approved; BeiGene’s ability to obtain and maintain protection of intellectual property for its medicines and technology; BeiGene\u2019s reliance on third parties to conduct drug development, manufacturing, commercialization, and other services; BeiGene\u2019s limited experience in obtaining regulatory approvals and commercializing pharmaceutical products; BeiGene\u2019s ability to obtain additional funding for operations and to complete the development of its drug candidates and achieve and maintain profitability; and those risks more fully discussed in the section entitled \u201cRisk Factors\u201d in BeiGene\u2019s most recent quarterly report on Form 10-Q, as well as discussions of potential risks, uncertainties, and other important factors in BeiGene\u2019s subsequent filings with the U.S. Securities and Exchange Commission. All information in this press release is as of the date of this press release, and BeiGene undertakes no duty to update such information unless required by law.<\/p>\n

\nTo access BeiGene media resources, please visit our <\/b>News & Media<\/b><\/a> <\/b>site.<\/p>\n

Contacts<\/b> <\/p>\n

\nInvestor Contact<\/b>
Liza Heapes
\n
+1 857-302-5663
\n
ir@beigene.com<\/a><\/p>\n

\nMedia Contact<\/b>
Kyle Blankenship
\n
+1 667-351-5176
\n
media@beigene.com<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

SAN MATEO, Calif.–(BUSINESS WIRE)–$BGNE #BeiGene—BeiGene, Ltd. (NASDAQ: BGNE; HKEX: 06160; SSE: 688235), a global oncology company that intends to change its name to BeOne Medicines Ltd., today announced it has entered into a global licensing agreement with CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (\u201cCSPC\u201d) for SYH2039, a novel methionine adenosyltransferase 2A (MAT2A)-inhibitor being explored … [Read more…]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-60489","6":"format-standard","7":"category-industry"},"yoast_head":"\nBeiGene Announces Global Licensing Agreement for MAT2A Inhibitor - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/beigene-announces-global-licensing-agreement-for-mat2a-inhibitor\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BeiGene Announces Global Licensing Agreement for MAT2A Inhibitor - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"SAN MATEO, Calif.–(BUSINESS WIRE)–$BGNE #BeiGene—BeiGene, Ltd. (NASDAQ: BGNE; HKEX: 06160; SSE: 688235), a global oncology company that intends to change its name to BeOne Medicines Ltd., today announced it has entered into a global licensing agreement with CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (\u201cCSPC\u201d) for SYH2039, a novel methionine adenosyltransferase 2A (MAT2A)-inhibitor being explored ... 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