{"id":60964,"date":"2025-03-20T19:02:41","date_gmt":"2025-03-20T18:02:41","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/feinstein-institutes-awarded-3-million-nih-grant-to-develop-devices-for-precision-vagus-nerve-stimulation-with-imec\/"},"modified":"2025-03-20T19:02:41","modified_gmt":"2025-03-20T18:02:41","slug":"feinstein-institutes-awarded-3-million-nih-grant-to-develop-devices-for-precision-vagus-nerve-stimulation-with-imec","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/feinstein-institutes-awarded-3-million-nih-grant-to-develop-devices-for-precision-vagus-nerve-stimulation-with-imec\/","title":{"rendered":"Feinstein Institutes Awarded $3 Million NIH Grant to Develop Devices for Precision Vagus Nerve Stimulation With Imec"},"content":{"rendered":"<div>\n<p>MANHASSET, N.Y.&#8211;(BUSINESS WIRE)&#8211;The <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ffeinstein.northwell.edu%2F&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=Feinstein+Institutes+for+Medical+Research&amp;index=1&amp;md5=896d63dfa39d6590ece91aa8fe0b009d\" rel=\"nofollow\" shape=\"rect\">Feinstein Institutes for Medical Research<\/a> has been awarded $3 million from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), in collaboration with imec, to pioneer a novel approach to vagus nerve stimulation (VNS). This research aims to develop more precise, safe and effective methods for stimulating specific fibers inside the vagus nerve, potentially transforming treatments for a range of chronic diseases.\n<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20250320197811\/en\/2416132\/5\/Zanos_Stavros_2023.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20250320197811\/en\/2416132\/22\/Zanos_Stavros_2023.jpg\"><\/a><br \/><a href=\"https:\/\/mms.businesswire.com\/media\/20250320197811\/en\/2416132\/5\/Zanos_Stavros_2023.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20250320197811\/en\/2416132\/21\/Zanos_Stavros_2023.jpg\"><\/a><br \/><a href=\"https:\/\/mms.businesswire.com\/media\/20250320197811\/en\/766145\/5\/Feinstein_logo.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20250320197811\/en\/766145\/22\/Feinstein_logo.jpg\"><\/a><br \/><a href=\"https:\/\/mms.businesswire.com\/media\/20250320197811\/en\/766145\/5\/Feinstein_logo.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20250320197811\/en\/766145\/21\/Feinstein_logo.jpg\"><\/a><\/p>\n<p>\nLed by <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ffeinstein.northwell.edu%2Finstitutes-researchers%2Four-researchers%2Fstavros-zanos-md-phd&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=Stavros+Zanos%2C+MD%2C+PhD&amp;index=2&amp;md5=dd3ba2ceec3dc6bf50be259b0691497b\" rel=\"nofollow\" shape=\"rect\">Stavros Zanos, MD, PhD<\/a>, this research will explore a cutting-edge method for stimulating nerves with greater precision. The team will use a specialized device, recently developed by Dr. Zanos\u2019s team and imec \u2014 a research and innovation hub in nanoelectronics and digital technologies. The team will use in-depth understanding of <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Feur02.safelinks.protection.outlook.com%2F%3Furl%3Dhttps%253A%252F%252Fwww.northwell.edu%252Fnews%252Fthe-latest%252Ffeinstein-institutes-report-on-early-mapping-of-vagus-nerve%26data%3D05%257C02%257CVojkan.Mihajlovic%2540imec.nl%257Cc222891198964531d8c008dd3aec0e47%257Ca72d5a7225ee40f09bd1067cb5b770d4%257C0%257C0%257C638731507706782848%257CUnknown%257CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%253D%253D%257C0%257C%257C%257C%26sdata%3D8rXVLCu1dxziraapvinfcjCDl2wBLSyWvprY6mvG0N8%253D%26reserved%3D0&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=anatomical+and+functional+organization&amp;index=3&amp;md5=01346a97e71723e70e36620932a25eb2\" rel=\"nofollow\" shape=\"rect\">anatomical and functional organization<\/a> of the vagus nerve, along with technology and interferential stimulation method introduced by imec.\n<\/p>\n<p>\n\u201cWe hope to enhance the efficacy of VNS and minimize unintended consequences or side effects. This has the potential to revolutionize treatments for conditions like rheumatoid arthritis, inflammatory bowel disease, and heart failure, which are all linked to inflammation,\u201d said Dr. Zanos. \u201cWe are grateful for this grant, which represents a significant step forward in the field of neuromodulation and bioelectronic medicine.\u201d\n<\/p>\n<p>\nThe research will focus on the vagus nerve, a major nerve that plays a crucial role in regulating bodily functions. The vagus nerve is the largest nerve in the body, stemming from the base of the brain, it branches into two, traveling down either side of the neck to various organs including the heart, lungs, stomach, digestive tract, spleen, and liver, among other places.\n<\/p>\n<p>\nThe joint research teams will explore how this therapy can be used to precisely target different vagal fibers, allowing for tailored stimulation of specific functions. For the past two years, Dr. Zanos\u2019 team, supported by a NIH SPARC grant, has been mapping the microscopic anatomy of the<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.northwell.edu%2Fnews%2Fthe-latest%2F6-7m-nih-grant-creates-first-human-vagus-nerve-anatomical-map&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=human+vagus+nerve&amp;index=4&amp;md5=b9ad2719771dc9c4950b6371d74a9b8c\" rel=\"nofollow\" shape=\"rect\"> human vagus nerve<\/a>. Knowledge gained from the mapping study, along with the devices developed by imec, could provide physicians with unprecedented level of control over activation of the vagus nerve, potentially improving treatment outcomes and reducing the burden of side effects for patients receiving VNS.\n<\/p>\n<p>\n\u201cThis important grant supports research into new ways to stimulate nerves in the body in order to treat serious medical conditions,\u201d said <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ffeinstein.northwell.edu%2Finstitutes-researchers%2Four-researchers%2Fkevin-j-tracey-md&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=Kevin+J.+Tracey%2C+MD%2C&amp;index=5&amp;md5=7181b9001c6e1ea741ebee1d2cd33726\" rel=\"nofollow\" shape=\"rect\">Kevin J. Tracey, MD,<\/a> president and CEO of the Feinstein Institutes and Karches Family Distinguished Chair in Medical Research. \u201cDr. Zanos and his colleagues are leading these cutting-edge efforts to selectively activate fibers in the vagus nerve in order to minimize side effects and maximize efficacy.&#8221;\n<\/p>\n<p>\nThe Feinstein Institutes for Medical Research is the global scientific home of <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ffeinstein.northwell.edu%2Finstitutes-researchers%2Fbioelectronic-medicine&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=bioelectronic+medicine&amp;index=6&amp;md5=8a13f8325ba2e92c1c323b7cdadc41d3\" rel=\"nofollow\" shape=\"rect\">bioelectronic medicine<\/a>, which combines molecular medicine, neuroscience, and biomedical engineering. At the Feinstein Institutes, medical researchers use modern technology to develop new device-based therapies to treat disease and injury.\n<\/p>\n<p>\nBuilding on years of research in molecular disease mechanisms and the link between the nervous and immune systems, Feinstein Institutes\u2019 researchers discovered neural targets that can be activated or inhibited with neuromodulation devices, like vagus nerve implants, to control the body&#8217;s immune response and inflammation. If inflammation is successfully controlled, diseases \u2013 such as arthritis, pulmonary hypertension, heart failure, inflammatory bowel diseases, diabetes, cancer and autoimmune diseases \u2013 can be treated more effectively.\n<\/p>\n<p>\nBeyond inflammation, using novel brain-computer interfaces, Feinstein Institutes&#8217; researchers developed techniques to bypass injuries of the nervous system so that people living with paralysis can regain sensation and use their limbs. By producing bioelectronic medicine knowledge, disease and injury could one day be treated with our own nerves without costly and potentially harmful pharmaceuticals.\n<\/p>\n<p>\nMost recently, Dr. Zanos published in <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.ahajournals.org%2Fdoi%2Fabs%2F10.1161%2FCIRCRESAHA.123.323679&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=Circulation+Research&amp;index=7&amp;md5=d0d87a5822ca86e1f5d8934df4720691\" rel=\"nofollow\" shape=\"rect\"><i>Circulation Research<\/i><\/a><i>, <\/i>an American Heart Association journal, scientific evidence of bioelectronic medicine and neuromodulation as an effective way to treat pulmonary hypertension, a cardiovascular disease with an inflammatory component, through a noninvasive, ultrasound-based therapy.\n<\/p>\n<p>\n<b><i>About the Feinstein Institutes<br \/>\n<br \/><\/i><\/b><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ffeinstein.northwell.edu%2F&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=The+Feinstein+Institutes+for+Medical+Research&amp;index=8&amp;md5=ef90e8e181a3d75ab9f9d04a84d50a95\" rel=\"nofollow\" shape=\"rect\"><i>The Feinstein Institutes for Medical Research<\/i><\/a><i> is the home of the research institutes of Northwell Health, the largest health care provider and private employer in New York State. Encompassing 50+ research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its six institutes of behavioral science, bioelectronic medicine, cancer, health system science, molecular medicine, and translational research. We are the global scientific leader in bioelectronic medicine \u2013 an innovative field of science that has the potential to revolutionize medicine. The Feinstein Institutes publishes two open-access, international peer-reviewed journals <\/i><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fmolmed.biomedcentral.com%2F&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=Molecular+Medicine&amp;index=9&amp;md5=d8ccad79462299bf1fa2ff7c79a8fb29\" rel=\"nofollow\" shape=\"rect\"><i>Molecular Medicine<\/i><\/a><i> and <\/i><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fbioelecmed.biomedcentral.com%2F&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=Bioelectronic+Medicine&amp;index=10&amp;md5=a3370df97bae9f6eccd1c0a3398f4516\" rel=\"nofollow\" shape=\"rect\"><i>Bioelectronic Medicine<\/i><\/a><i>. Through the <\/i><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.northwell.edu%2Feducation-and-resources%2Felmezzi-graduate-school-of-molecular-medicine&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=Elmezzi+Graduate+School+of+Molecular+Medicine&amp;index=11&amp;md5=e942893476e73100f1071242feb55282\" rel=\"nofollow\" shape=\"rect\"><i>Elmezzi Graduate School of Molecular Medicine<\/i><\/a><i>, we offer an accelerated PhD program. For more information about how we produce knowledge to cure disease, visit <\/i><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ffeinstein.northwell.edu%2F&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=http%3A%2F%2Ffeinstein.northwell.edu&amp;index=12&amp;md5=844fa3c7108b0af1add2077f72abd708\" rel=\"nofollow\" shape=\"rect\"><i>http:\/\/feinstein.northwell.edu<\/i><\/a><i> and follow us on <\/i><a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fthe-feinstein-institutes-for-medical-research&amp;esheet=54226880&amp;newsitemid=20250320197811&amp;lan=en-US&amp;anchor=LinkedIn&amp;index=13&amp;md5=b725f05839c32b6195a86f8381549ad6\" rel=\"nofollow\" shape=\"rect\"><i>LinkedIn<\/i><\/a><i>.<\/i>\n<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\nJulianne Mosher Allen<br \/>\n<br \/>516-880-4824<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;a&#x69;&#108;t&#x6f;&#58;&#x6a;&#x6d;o&#x73;&#104;e&#x72;&#97;&#x6c;&#108;e&#x6e;&#64;n&#x6f;&#114;&#x74;&#104;w&#x65;&#108;&#x6c;&#x2e;e&#x64;&#117;\" rel=\"nofollow\" shape=\"rect\">&#x6a;&#109;o&#x73;&#104;e&#x72;&#97;l&#x6c;&#101;n&#x40;&#110;o&#x72;&#x74;h&#x77;&#x65;&#108;&#x6c;&#x2e;&#101;&#x64;&#x75;<\/a>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>MANHASSET, N.Y.&#8211;(BUSINESS WIRE)&#8211;The Feinstein Institutes for Medical Research has been awarded $3 million from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), in collaboration with imec, to pioneer a novel approach to vagus nerve stimulation (VNS). This research aims to develop more precise, safe and effective &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/feinstein-institutes-awarded-3-million-nih-grant-to-develop-devices-for-precision-vagus-nerve-stimulation-with-imec\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-60964","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Feinstein Institutes Awarded $3 Million NIH Grant to Develop Devices for Precision Vagus Nerve Stimulation With Imec - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/feinstein-institutes-awarded-3-million-nih-grant-to-develop-devices-for-precision-vagus-nerve-stimulation-with-imec\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Feinstein Institutes Awarded $3 Million NIH Grant to Develop Devices for Precision Vagus Nerve Stimulation With Imec - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"MANHASSET, N.Y.&#8211;(BUSINESS WIRE)&#8211;The Feinstein Institutes for Medical Research has been awarded $3 million from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), in collaboration with imec, to pioneer a novel approach to vagus nerve stimulation (VNS). 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This research aims to develop more precise, safe and effective ... 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