{"id":62011,"date":"2025-10-13T13:03:46","date_gmt":"2025-10-13T11:03:46","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/daiichi-sankyo-continues-to-transform-standards-of-care-for-patients-with-three-landmark-breast-cancer-trials-and-additional-data-across-industry-leading-adc-portfolio-at-esmo\/"},"modified":"2025-10-13T13:03:46","modified_gmt":"2025-10-13T11:03:46","slug":"daiichi-sankyo-continues-to-transform-standards-of-care-for-patients-with-three-landmark-breast-cancer-trials-and-additional-data-across-industry-leading-adc-portfolio-at-esmo","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/daiichi-sankyo-continues-to-transform-standards-of-care-for-patients-with-three-landmark-breast-cancer-trials-and-additional-data-across-industry-leading-adc-portfolio-at-esmo\/","title":{"rendered":"Daiichi Sankyo Continues to Transform Standards of Care for Patients with Three Landmark Breast Cancer Trials and Additional Data Across Industry-Leading ADC Portfolio at ESMO"},"content":{"rendered":"<div>\n<ul class=\"bwlistdisc\">\n<li>\nBack-to-back Presidential Symposium presentations of ENHERTU from DESTINY-Breast11 and DESTINY-Breast05 demonstrate its potential to become a foundational treatment in curative-intent settings of HER2 positive early breast cancer<\/li>\n<li>\nLate-breaking data from TROPION-Breast02 showcase that DATROWAY is the first and only therapy to significantly improve overall survival versus chemotherapy as first-line treatment for patients with first-line metastatic triple negative breast cancer for whom immunotherapy is not an option<\/li>\n<li>\nData from eight additional trials \u2013 DESTINY-Breast09, REJOICE-Ovarian01, IDeate-Lung01, TROPION-PanTumor03, DESTINY-Gastric04, DESTINY-CRC02, DESTINY-PanTumor02 and DS-3939 \u2013 further support the strength of the DXd ADC portfolio of Daiichi Sankyo across multiple types of cancer<\/li>\n<li>\nInvestor conference call to discuss ESMO<\/li>\n<\/ul>\n<p>TOKYO &amp; BASKING RIDGE, N.J.&#8211;(BUSINESS WIRE)&#8211;Daiichi Sankyo (TSE: 4568) will present new clinical research across its DXd antibody drug conjugate (ADC) portfolio with four late-breaking presentations from more than 20 abstracts at the 2025 European Society for Medical Oncology (#ESMO25) Congress.<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20251013032388\/en\/2606266\/4\/DaiichiSankyo-logo.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20251013032388\/en\/2606266\/22\/DaiichiSankyo-logo.jpg\"><\/a><br \/><a href=\"https:\/\/mms.businesswire.com\/media\/20251013032388\/en\/2606266\/4\/DaiichiSankyo-logo.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20251013032388\/en\/2606266\/21\/DaiichiSankyo-logo.jpg\"><\/a><\/p>\n<p>\nData at ESMO will spotlight the company\u2019s advances towards creating new standards of care for patients with breast cancer, including back-to-back presentations during <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fsession%2Flist%3Fq%3DLBA1%26r%3Dst%257E12___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NWRkODo2YzdiMTYwNzZmMmNkYWUwOGFmNmZmZWFhNGU2YTllMjE1YjY3ZGNjYmI1OWJmNjYwOTA3MzAyNjYwOTczNDgxOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=Presidential+Symposium+I&amp;index=1&amp;md5=126e9d743aacbad98e609991f5862fc2\" rel=\"nofollow\" shape=\"rect\">Presidential Symposium I<\/a> featuring data from the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT05113251___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6Y2E4MDo4YjZjNDdiYTk1MDQ2N2MzZGUzYWQxZTA4ODgyZjk0ZjFlYmFkNjIwOGNlZGU0NzNkODI2MmQ3NWE2YWJhYjNiOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=DESTINY-Breast11&amp;index=2&amp;md5=eae2e906f101cf5e1a9afb7ef40990fa\" rel=\"nofollow\" shape=\"rect\">DESTINY-Breast11<\/a> (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D291O___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YWEwMzo5NzMzNzE0ZjRjZTM1NGRmOGYxYThkZGI1YjU2OGZhMjc3MzQ0NTIzZDE3YzU1NjY3MTQ1OTI5OGE5M2ViYTgwOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=291O&amp;index=3&amp;md5=a61a7768ab94df147dd23489db0c2691\" rel=\"nofollow\" shape=\"rect\">291O<\/a>) and <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT04622319___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YTY4MTozY2U2NDYxZmY3OTRhNGNiODdhMmY2OWFhOThkZjQxMWRkODFmNmVlYzlhZjIyNTkxMTU4MTdhNDY5YzIwMGEwOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=DESTINY-Breast05&amp;index=4&amp;md5=c1789a6f16e99de23b798b9087c773eb\" rel=\"nofollow\" shape=\"rect\">DESTINY-Breast05<\/a> (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3DLBA1___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MTI5MTo5MGYwNjEwYzEzYTZlNTM0OTc5MzIzNjQxYzAxNTdkOTM2YWRhYWNmOTcwNTE0MjI1NWVkYjkyMjA1ZTZiMTExOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=LBA1&amp;index=5&amp;md5=9c265ced95dc3811ffa2a7e00797e7d4\" rel=\"nofollow\" shape=\"rect\">LBA1<\/a>) phase 3 trials. Results of these two landmark trials will showcase the potential of ENHERTU<sup>\u00ae<\/sup> (trastuzumab deruxtecan) to become a foundational treatment in curative-intent settings of HER2 positive early breast cancer.<\/p>\n<p>\nLate-breaking DATROWAY<sup>\u00ae<\/sup> (datopotamab deruxtecan) data from the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT05374512___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YmFhMDo3OGY4MGI2MTFjZDQwYzk0YjkxNTAwMDA3YmZhNDNjMGE0NWRlOWY3Yzg1YzU0NjYwNjE5MjcyZTI5ZTc1ZTE5OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=TROPION-Breast02&amp;index=6&amp;md5=01cd83bee2556ef716bf236b9f688897\" rel=\"nofollow\" shape=\"rect\">TROPION-Breast02<\/a> phase 3 trial (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fshow%2Fsession%2F115___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NWQ4ZTo0MGVhNTI5ZDYyYjRhNzU0NzM5ZDk3NzVlZGU3MGVhNDI1MTViOWI4ZGEyM2UwMjYzNmVjY2FlNzEwMzhkZmFlOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=LBA21&amp;index=7&amp;md5=48c0e3b1038b4101b94c43e2e0113450\" rel=\"nofollow\" shape=\"rect\">LBA21<\/a>), representing the first trial ever to demonstrate a significant improvement in overall survival compared to chemotherapy as first-line treatment for patients with locally recurrent inoperable or metastatic triple negative breast cancer (TNBC) for whom immunotherapy is not an option, will be featured in a proffered paper session.<\/p>\n<p>\n\u201cData from these three landmark trials demonstrate how the DXd ADC portfolio of Daiichi Sankyo continues to transform standards of care for patients with breast cancer. The findings from DESTINY-Breast11 and DESTINY-Breast05 highlight the potential of ENHERTU to become a foundational treatment in the curative-intent settings of HER2 positive early breast cancer,\u201d said Ken Takeshita, MD, Global Head, R&amp;D, Daiichi Sankyo. \u201cAdditionally, the DATROWAY results from TROPION-Breast02 represent the first time ever that an overall survival benefit has been demonstrated in the first-line setting of patients with metastatic triple negative breast cancer for whom immunotherapy is not an option. Couple these impressive results for DATROWAY with previous results seen with ENHERTU in the HER2 positive, HER2 low and HER2 ultralow disease settings, Daiichi Sankyo will now have two medicines with the potential to treat approximately 90 percent of patients with metastatic breast cancer.\u201d<\/p>\n<p>\nAdditional breast cancer data at ESMO includes a mini oral presentation of data from Arm 7 and Arm 8 of the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT03742102___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NDQ4NTphYjE4OWE3NWZiN2I0NTdiMzg4NGM1MTQyNGRkZTY3MDFmZmFkYzc4ZWI1ZWM4MDU2YWE1MDczZDkwMjNjZWU2OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=BEGONIA&amp;index=8&amp;md5=34bb2360af924c0aa23a7661d5bb02c2\" rel=\"nofollow\" shape=\"rect\">BEGONIA<\/a> phase 1\/2 trial (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D555MO___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NWNmYjpmOWU5ZTFjOWQ4MjRhOTMxMWU1NzNhYzM3MTZkYjM3NjI4YjRjZThmZTI1ZDNkZWE5M2RjY2ZhODU1MzI5NDA1OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=555MO&amp;index=9&amp;md5=2c3843e4745354792768da6c78bf3200\" rel=\"nofollow\" shape=\"rect\">555MO<\/a>) evaluating DATROWAY plus durvalumab in patients with first-line metastatic TNBC. The efficacy and safety of this combination strategy is being further investigated in three phase 3 trials \u2013 <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT05629585___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6M2ZlMzozMjZkMGVmMzE2Y2M5NmEyYTlkY2YyNTZhZWEzN2I4YzA0OGE2MTlmY2ExNzcwOTI5N2FiMzA5Mjg5ZGU3NGQzOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=TROPION-Breast03&amp;index=10&amp;md5=58b5c569e384e56dbbcbbe6626dce6c1\" rel=\"nofollow\" shape=\"rect\">TROPION-Breast03<\/a>, <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT06112379___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6OTRlZTpjZDcwMDEzOWE3NDhiM2VmNWQ5NmJkNDU4MmQ3YWFjOTE5ZWI5N2YwNWY1OGU1NjQ5ZTMwMjAyYzU0YjY4ZjY4OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=TROPION-Breast04&amp;index=11&amp;md5=0774fa5d42529c76f13c1ba95234a0ec\" rel=\"nofollow\" shape=\"rect\">TROPION-Breast04<\/a> and <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT06103864___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6OTAwYToyY2NhMTAwOThjOGY0ZmM5ZTQ5ZTUwNDUxYTBjNDU1ODI2MGM5ODI3ZjdlN2EwZmFiNTNlODQ3YjFhMmM4NzYyOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=TROPION-Breast05&amp;index=12&amp;md5=10f3e4b8c830d8b9309ded44cb03e8a2\" rel=\"nofollow\" shape=\"rect\">TROPION-Breast05<\/a> \u2013 across stages and treatment settings of TNBC.<\/p>\n<p>\n<b>Trials Supporting Three Recent Breakthrough Therapy Designations Showcased<br \/>\n<br \/><\/b>Data from additional late-stage trials \u2013 <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT04784715___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6OTE3YzpkNWUyZDBmYWZiZDE2ZDhlNWJlM2E4NDUzN2RjZmFlMDZlMmZjZjUzZTcwNDM1NjdkNWI4Yzk1ZWZiN2VjODE0OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=DESTINY-Breast09&amp;index=13&amp;md5=865cd3791ec52947f66179f905baa06e\" rel=\"nofollow\" shape=\"rect\">DESTINY-Breast09<\/a>, <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT06161025___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MDYxYjozM2M4NDgyM2UzYzhkYjEwM2E0YWYxNDZkNWVmNWRkMDgxNjAyNTUwMDVkY2RmMTY2ODg1OTY3NzFhNGI2YTg3OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=REJOICE-Ovarian01&amp;index=14&amp;md5=9982e63e414925d35208ae444e448215\" rel=\"nofollow\" shape=\"rect\">REJOICE-Ovarian01<\/a> and <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT05280470___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6N2Q5NjpjZGM4NTU2NTZkYmQ3NmMxNjg0MWQxZWQ4YWQ0Yjg2ZjM0ZjM4NGUxOGVlODE3ZmUyNGUzYTZlNjk4YWU1ZmVhOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=IDeate-Lung01&amp;index=15&amp;md5=6d30b1a23b7255d55b324556563ac545\" rel=\"nofollow\" shape=\"rect\">IDeate-Lung01<\/a> \u2013 that supported three recent Breakthrough Therapy Designations (BTD) in the U.S. for <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fdaiichisankyo.us%2Fpress-releases%2F-%2Farticle%2Fenhertu-plus-pertuzumab-granted-breakthrough-therapy-designation-in-the-us-as-first-line-therapy-for-patients-with-her2-positive-metastatic-breast-cancer___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NTBmMTpjMjE4YWVmYWM1ZjIwNWJkYWMyNjQ1ZmViZDY1MWI0NjAyYzM0NmRmYmFiN2UyYzc4MjY0NmQxZTVmNWI2YzhiOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=ENHERTU&amp;index=16&amp;md5=881fe7642a32af568260d431a638c658\" rel=\"nofollow\" shape=\"rect\">ENHERTU<\/a>, <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fdaiichisankyo.us%2Fpress-releases%2F-%2Farticle%2Fraludotatug-deruxtecan-granted-breakthrough-therapy-designation-by-us-fda-for-patients-with-cdh6-expressing-platinum-resistant-ovarian-primary-peritoneal-or-fallopian-tube-cancers-previously-treated-with-bevacizumab___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YzZhYjowYTMyYWVlNTlhMTYwZjg3MTc0NzUyODFjMTFiZGZlNDFlNzI0YjZiYWViZjVjYjFlYWUzYjI3MzVmOWRhNTYzOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=raludotatug+deruxtecan&amp;index=17&amp;md5=e3db92c54acbb196077d5d33107186e0\" rel=\"nofollow\" shape=\"rect\">raludotatug deruxtecan<\/a> (R-DXd) and <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fdaiichisankyo.us%2Fpress-releases%2F-%2Farticle%2Fifinatamab-deruxtecan-granted-breakthrough-therapy-designation-by-us-fda-for-patients-with-pretreated-extensive-stage-small-cell-lung-cancer___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MGI3OToxZmJiMjcwZTQyNDQ2NTMzYzNhMmFlNmNhZWQ5YWIxY2EwZTg0ZWFhYzljOTBhOTkwMzRjYmIxNTI1NjJjZjI4OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=ifinatamab+deruxtecan&amp;index=18&amp;md5=30c030163e77974db33561e6371ccbaa\" rel=\"nofollow\" shape=\"rect\">ifinatamab deruxtecan<\/a> (I-DXd) will be showcased at ESMO.<\/p>\n<p>\nTwo late-breaking proffered paper sessions will highlight the primary analysis from the phase 2 part of the REJOICE-Ovarian01 phase 2\/3 trial (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3DLBA42___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NTcxMDo2ZjZlNWM5MzVmZmE0N2M0OGQ1OGZjN2VjYWY0MWJhMDhlNGMyOGMyNzAxYTc0YTU3MzExMWNhYjcxNDg4ZmE0OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=LBA42&amp;index=19&amp;md5=f4e8541021c0566890cfa8952725c598\" rel=\"nofollow\" shape=\"rect\">LBA42<\/a>) of raludotatug deruxtecan in patients with previously treated platinum-resistant ovarian cancer, and additional analyses of key subgroups of interest from the DESTINY-Breast09 phase 3 trial (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3DLBA18___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MDQ2YTo3MTg0ZDNkZGRjZDVmMzM2ZjZlN2E2Y2IwZjljMDJhM2M5ZGQ5MGNlN2FlODQ1NGVmNDgzODNjNjJkZjQxZjhmOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=LBA18&amp;index=20&amp;md5=72229e1e49e54973956d8a3bdd84ba13\" rel=\"nofollow\" shape=\"rect\">LBA18<\/a>) evaluating ENHERTU plus pertuzumab versus THP (taxane, trastuzumab, pertuzumab) for the first-line treatment of patients with HER2 positive metastatic breast cancer. Results of DESTINY-Breast09 formed the basis for a supplemental Biologic License Application in the U.S. for ENHERTU, which was recently <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fdaiichisankyo.us%2Fpress-releases%2F-%2Farticle%2Fenhertu*25C2*25AE-plus-pertuzumab-granted-priority-review-in-the-us-as-first-line-treatment-for-patients-with-her2-positive-metastatic-breast-cancer___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZGI4ZDoxNGRmODhiODk3ZTAyOGNlMmU3MDQxYzE0Yzg4ZTc0YTlkOWEwNTk4M2RmODUxZTk1NGE4YmY0MGRiMTljOWI5OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=granted&amp;index=21&amp;md5=56d441c6c18f230241bbb6308d30f556\" rel=\"nofollow\" shape=\"rect\">granted<\/a> Priority Review under the Real-Time Oncology Review program.<\/p>\n<p>\nDetailed results highlighting the intracranial activity of ifinatamab deruxtecan from the IDeate-Lung01 phase 2 trial (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D2760MO___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZTI0NzplN2IxMjBlY2Y0Y2U2MjU0YjExYzQxNDM2NjM5YzVlZDUxNzNkYTllNTQzM2Y3NTU0NjYyOGVhOWY1ZGQ0ZmQzOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2760MO&amp;index=22&amp;md5=de09936180d305c12adf7a01e6bdd801\" rel=\"nofollow\" shape=\"rect\">2760MO<\/a>) in patients with previously treated extensive-stage small cell lung cancer (ES-SCLC) and baseline brain metastases will be highlighted during a mini oral session. The primary results of IDeate-Lung01 were <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fdaiichisankyo.us%2Fpress-releases%2F-%2Farticle%2Fifinatamab-deruxtecan-demonstrated-clinically-meaningful-response-rates-in-patients-with-extensive-stage-small-cell-lung-cancer-in-ideate-lung01-phase-2-trial___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6OGU2NDpiMjczZGRhZDRlYjY3OGVhNzNkNDhkYzdkNzJiNTUwNzgyOTlhYzY3YWZhNzRjMjE0ZjQ1NDFhNjVjYzgwYWU1OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=presented&amp;index=23&amp;md5=2eeefd4e04d25a1e2e3fbe8b07b2a39c\" rel=\"nofollow\" shape=\"rect\">presented<\/a> last month at the 2025 World Conference on Lung Cancer (#WCLC25).<\/p>\n<p>\n<b>Progress Continues in Multiple Cancers Across the DXd ADC Portfolio of Daiichi Sankyo<br \/>\n<br \/><\/b>Additional mini oral sessions at ESMO will feature the first presentation of data from two early phase trials from the DXd ADC portfolio of Daiichi Sankyo. These include preliminary results from the first-in-human <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT05875168___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NWEyNDo0N2IyMWNlNDgxZTBmODY3Y2FjYWI3YjgyODNiYjJmZDZiMGZlNGQ2YTkwNGE3OGIzOTNhMTJkN2E3OThhNzYxOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=phase+1%2F2+trial&amp;index=24&amp;md5=8f76084dd9b22a827f389762129ccf04\" rel=\"nofollow\" shape=\"rect\">phase 1\/2 trial<\/a> of DS-3939 (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D917O___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZTJiNDo4MDNmZGY5MDRkNjIxZDI1ZTMxNTk0NmJkNzQxZmRmZTIxZDBjODFmMmY3NTMyNGM2OGU1OTg0YTAyMGZjMDczOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=917O&amp;index=25&amp;md5=1eed2555e288adaea1a9a78177b324bd\" rel=\"nofollow\" shape=\"rect\">917O<\/a>), the sixth DXd ADC in clinical development, in patients with previously treated advanced solid tumors refractory to standard treatment, as well as initial results from a sub-study of the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT05489211___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6OTRiNjpkMWFjYmMwZGNkZDM1YzA2MDgwNWY2ZTNkY2YzOGRlNmJhMWYyOGRhOThjYTM0MWJjNTZhZjRkODUzMjMxYjkwOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=TROPION-PanTumor03&amp;index=26&amp;md5=f0de402fad7a11ace39e3e3bfdf9161c\" rel=\"nofollow\" shape=\"rect\">TROPION-PanTumor03<\/a> phase 2 trial (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D3072MO___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NjhiODplMDZkNWM0YmFiNDQ5Y2ViMDQ4OGY0MjgxNjQyYjg4OWMwODdlZWExM2FjNzU5ZTNmYzJmNWQwN2E2ZGFlOGRkOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=3072MO&amp;index=27&amp;md5=420a0f34449869136d6b551c4caec9af\" rel=\"nofollow\" shape=\"rect\">3072MO<\/a>) evaluating DATROWAY plus rilvegostomig, AstraZeneca\u2019s PD-1\/TIGIT bispecific antibody, in patients as first-line or second-line locally advanced or metastatic urothelial carcinoma.<\/p>\n<p>\nFinal analyses from two trials \u2013 <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT04744831___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZDVmYTo3ZWYzZDM1NTY2ZGE0MzA2NmE4NzNlOTM1MzI4OTUzOGYzNmY5YTM5NmJkZTVhZWMzY2NlZGJjNzA4N2U2ODlkOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=DESTINY-CRC02&amp;index=28&amp;md5=c0d8ca3fccc0497b307556767e951e1b\" rel=\"nofollow\" shape=\"rect\">DESTINY-CRC02<\/a> and <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT04482309___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZGU2Zjo3ZDcxOWY3YTdhOTAwNTM5NzJiMGRkODY3YWQ3OGFmYWFlOWY4YzQ0OTYxZjY5YWE2YzhjNWY2YmY3ZmExOWNiOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=DESTINY-PanTumor02&amp;index=29&amp;md5=3a2f89292f97e7a5a148571dad0817e9\" rel=\"nofollow\" shape=\"rect\">DESTINY-PanTumor02<\/a> \u2013 that supported the tumor agnostic indication of ENHERTU, which is now approved in more than 10 countries\/regions worldwide, will be presented. A mini oral session will feature the final analysis from the DESTINY-CRC02 phase 2 trial (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D737MO___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MWY0OToyZjA4MDVjNWJkMzE5MGRjZmRhY2JkZmZmNTUzYTljY2U3NTVjN2I4NGY5MjBkN2RiYTRhZmFkYzQ1NWVlOTk1OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=737MO&amp;index=30&amp;md5=78c45db60ee7769228d3f03107325588\" rel=\"nofollow\" shape=\"rect\">737MO<\/a>) of ENHERTU in patients with previously treated HER2 positive metastatic colorectal cancer while two poster presentations will highlight the final results (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D957P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YTgzNDpiOWE4YzJiZGMwNTE0ZDBjMjliNGI2MjlkOTY0YzM1NGE0NjI0NDA1NWY5YTM0NWNiZGRhNjg0Yzc2Njk3MmFkOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=957P&amp;index=31&amp;md5=38ff3f64f41c3c240e710b838ab493b1\" rel=\"nofollow\" shape=\"rect\">957P<\/a>) and an exploratory biomarker analysis (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D145P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6Nzg1ZjphNTkzZThmOTcxOTUwN2QwMTJlNGFkZDE0M2UzODhlNTRiZTFiZjIyYTY3ZDAxMjEzN2I4OTA5ZmVmZTk5NDk2OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=145P&amp;index=32&amp;md5=f8d13139e9f6f09bc65926fffe5d8d91\" rel=\"nofollow\" shape=\"rect\">145P<\/a>) from part 1 of the DESTINY-PanTumor02 phase 2 trial in patients with previously treated HER2 expressing solid tumors. Additional regulatory submissions seeking a tumor agnostic approval in patients with HER2 positive metastatic solid tumors currently are under review in the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fwww.daiichisankyo.com%2Ffiles%2Fnews%2Fpressrelease%2Fpdf%2F202509%2F20250911_E.pdf___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQxM2RjZjllYjcyZjEzODI0ZGY1ZWY1NDExYTBmNDE0Ojc6MzU1ODo2NTZhZjBhNDRmMzlhMmRjZmMzNzMxYjE4NjFlNGVlMDRjMTY1ZTA1Yzg2MDZkZDVkYjI4YWU3ODQwMzQ1ZTQyOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=EU&amp;index=33&amp;md5=0696efa880333b15314fa73473cbc127\" rel=\"nofollow\" shape=\"rect\">EU<\/a> and <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fwww.daiichisankyo.com%2Ffiles%2Fnews%2Fpressrelease%2Fpdf%2F202504%2F20250424_E.pdf___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQxM2RjZjllYjcyZjEzODI0ZGY1ZWY1NDExYTBmNDE0Ojc6ZTg3MzpmODllMWMyZTBmYmQ2OWYyY2FhYjFhODg2MTFmYzg4ZjM3ODRhZWEyYTM3ODE5MDA4ZWUyZWE1ZGIxZjgzNjNiOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=Japan&amp;index=34&amp;md5=f267ffb5cc66a32cb355c429880e5241\" rel=\"nofollow\" shape=\"rect\">Japan<\/a>.<\/p>\n<p>\nFurther sub-analyses from the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT04704934___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6N2RmZDplZTI5ZTQzZTM2ZDIwZTBjNzllZWU5Y2VhOTg5MDQyYmFiNGRlNmYyMDg3MTQzN2IyNWIxOWIwNWM3YjIzNDY0OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=DESTINY-Gastric04&amp;index=35&amp;md5=afd0e3e1c52d80275691dd4605ce43d5\" rel=\"nofollow\" shape=\"rect\">DESTINY-Gastric04<\/a> phase 3 trial of ENHERTU versus ramucirumab plus paclitaxel in the second-line treatment of patients with HER2 positive metastatic gastric cancer or gastroesophageal junction (GEJ) adenocarcinoma will be presented as a poster presentation (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2099P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MTNiODpiMDBkMDQ1Y2FkN2I2MmU5YzJmZTExZTMzNjViYjFhZDA4NzM4NmQ1OWE3ZWY1Yzc0MjFiOTVlN2U0M2Y5NjI2OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2099P&amp;index=36&amp;md5=abd61840f2afc06557a13b2bbe56b31b\" rel=\"nofollow\" shape=\"rect\">2099P<\/a>) reporting the concordance of central HER2 testing with local HER2 testing along with additional efficacy and safety analyses. Data from <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT04989816%3Fterm%3DDESTINY-Gastric06%26rank%3D1___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6OGYzMjo4YmNiOTc4YmFlOTg0NjNmZTU4NjI5MDc0NDJkNGZmZjhmMThiZWZlYmFmZjBiZGJiZTJmY2ExOTEzNTI1ZjAxOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=DESTINY-Gastric06&amp;index=37&amp;md5=70f0c374b9accff711c3c6476386b2ef\" rel=\"nofollow\" shape=\"rect\">DESTINY-Gastric06<\/a>, a phase 2 trial in patients from China with HER2 expressing advanced gastric or GEJ adenocarcinoma who have received at least two prior regimens including a fluoropyrimidine agent and a platinum agent, will be presented in two poster presentations. The first poster (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2105P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZjU2MjphMTJlMTgxY2JhMGVkZTZmYmQzZDMwYmNkM2RhM2Y3MDA3OGM5ZDEzMGU4NjE4ZTcxOWY3NzA1ZDQzZjdhN2QwOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2105P&amp;index=38&amp;md5=b9c415188f1e9c849462dd1bc55dc12d\" rel=\"nofollow\" shape=\"rect\">2105P<\/a>) will feature an analysis of patients that received prior anti-HER2 treatment other than or in addition to trastuzumab. The second poster (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2175P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NWJlMjpjM2UwOGYzMmE2MTY1NjMwN2YxMGRmNGYyMTBjOWY3MDUzOTdkOTg1YWE2MDVhNGU0YzZhYmJlOWI0ODQ3YjlhOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2175P&amp;index=39&amp;md5=485ec35149ef509bddeaa52ca90e22ae\" rel=\"nofollow\" shape=\"rect\">2175P<\/a>) will report the risk of hepatitis B virus reactivation in patients with past or resolved HBV or inactive chronic HBV infection treated with ENHERTU.<\/p>\n<p>\nUpdates of progress in lung cancer include a mini oral session reporting updated results from a <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT04471727___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NmZmMTpkNTg2ZjE2YmE5MGI4Mzk0OTYyYjliMmU1YmY4ZGI0NThhZGNjNDBkZDFhYTRhYTNmZGE3ZTkwNjk5MWZiZTY2OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=phase+1%2F2+trial&amp;index=40&amp;md5=9dbe426d0824bd0f5cef55c4652fd3dc\" rel=\"nofollow\" shape=\"rect\">phase 1\/2 trial<\/a> of gocatamig (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D2758MO___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6Mzc3ZTowMDBlN2RlYjc0OTRmY2I2NWZmN2RiZTQzYmJmMTM0MzI3YzEyNzVmY2I1NDVhMDQ5ZWMwYWZlOTJiMjVjMjgzOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2758MO&amp;index=41&amp;md5=d08db99e7e94a285de27b6881e9905bd\" rel=\"nofollow\" shape=\"rect\">2758MO<\/a>), a DLL3 targeting T-cell engager being jointly developed by Merck, in patients with small cell lung cancer and other neuroendocrine cancers, as well as a poster presentation that will highlight the initial safety results from a <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT06244485___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YTY4NToxOTQ0MTg1Mzc5ODE5MzA2YzViYzllODkwM2RkOTMwMDU4MDM0MDhlMTVlNjMxYzE3YTliNjBlYmEzOWQ0YzJmOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=phase+1b+trial&amp;index=42&amp;md5=99306d34cac597fd7ec276e26ca8cae4\" rel=\"nofollow\" shape=\"rect\">phase 1b trial<\/a> of valemetostat (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2023P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YjE4YjpmYzExOGZiMDVhNjhiOTU4NDY0ZDEzMjFhMzU3ZmI2MmI4MWY4MzM4NTYzYjhlZjk1MGY5OWIxMjlkZmIzZWVmOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2023P&amp;index=43&amp;md5=e757c19dcfe1e3eff3ad5f77c2ac051a\" rel=\"nofollow\" shape=\"rect\">2023P<\/a>), a dual EZH1 and EZH2 inhibitor, in combination with DATROWAY in patients with previously treated advanced non-squamous non-small cell lung cancer (NSCLC).<\/p>\n<p>\n<b>Trials-in-Progress Across Daiichi Sankyo\u2019s Oncology Portfolio<br \/>\n<br \/><\/b>Several trials-in-progress poster presentations at ESMO further highlight the Daiichi Sankyo R&amp;D strategy of continuing to expand the DXd ADC portfolio to address a broad spectrum of unmet needs for patients with cancer.<\/p>\n<p>\nA trial-in-progress poster will highlight the design of the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT06989112___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MjgyOTo1NGM3NjExNjJmM2I4Y2QzN2M2YTY0NGQxMmZjNGRkZTUxMjcwOTRhM2JmNDI2MDRkM2Q0NGU3NDcxMTA4ZGE4OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=DESTINY-Endometrial01&amp;index=44&amp;md5=7a2b19cf4ba3b5c227ac8491b69bc898\" rel=\"nofollow\" shape=\"rect\">DESTINY-Endometrial01<\/a> phase 3 trial (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D1223TiP___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NTA4NzpkZmI3ZmMwYjliZmRlYjI2MDI2NTRlOGFjNmY1N2NjOTgwNzBmODk3OThlZTg2MjhlYjJiZTJjYTc0MjBlZDg3OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=1223TiP&amp;index=45&amp;md5=2c5066e84b8b49e9156684a59114889e\" rel=\"nofollow\" shape=\"rect\">1223TiP<\/a>) evaluating ENHERTU in combination with rilvegostomig or pembrolizumab versus platinum-based chemotherapy (carboplatin and paclitaxel) in combination with pembrolizumab as a first-line therapy in patients with HER2 expressing (IHC 3+\/ 2+), mismatch repair proficient (pMMR) primary advanced or recurrent endometrial cancer.<\/p>\n<p>\nThree phase 2 trials-in-progress will include the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT06797635___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MDhjMDo4ZWI3MGFhNmJhMTJmZmVlNGEzNzBmZDExYTY1YjU2NzAzNzMzNDQxOWZjNWVhMWVhNmY4MjEzMTQzZWY4Y2NhOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=HERTHENA-Breast03&amp;index=46&amp;md5=6c6ad06d618f1bc53d10aef96cda8fd8\" rel=\"nofollow\" shape=\"rect\">HERTHENA-Breast03<\/a> trial (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D463eTiP___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQxM2RjZjllYjcyZjEzODI0ZGY1ZWY1NDExYTBmNDE0Ojc6NWVkZDpkNDZhOWNkNTZjMzM3YzkwOTRjM2E0NDc0YmRlN2FmNDcxYzVjMjdjZWY0YjI4MGQ4YTkxOWQ2ZTUxMDUwYWIxOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=463eTiP&amp;index=47&amp;md5=6aa7492cb83f1ce334b72207ec1533e0\" rel=\"nofollow\" shape=\"rect\">463eTiP<\/a>) evaluating neoadjuvant patritumab deruxtecan (HER3-DXd) plus pembrolizumab before or after pembrolizumab plus chemotherapy in patients with high-risk early-stage TNBC or HR low positive\/HER2 negative breast cancer; the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT06864169___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZmViODo4MGE4NjU3ZDM3Y2Y1NGVjOTU0Zjc2YWQ4NjY5ZDE5MTE3OGNmMTc1NTc2NGIxODI4YmRkNTc3YzAzMzkzYzc2OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=REJOICE-GI01&amp;index=48&amp;md5=73d8f0522248ef16e0312dba6fddcdd5\" rel=\"nofollow\" shape=\"rect\">REJOICE-GI01<\/a> trial (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D1001TiP___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZjJlNzo4OTNlYjg2OWU4ZTQ0NTY2MWM0MmVmNjQzNGI5NThmMzM5OWU2NmY5MzE4ZTZmZjhhY2NiYjkzNjFlOTQxYmZhOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=1001TiP&amp;index=49&amp;md5=c8501d49b5625a191cd036f07c937f2c\" rel=\"nofollow\" shape=\"rect\">1001TiP<\/a>) evaluating the efficacy and safety of raludotatug deruxtecan in patients with gastrointestinal cancers, including pancreatic ductal adenocarcinoma, gastroesophageal adenocarcinoma, biliary tract and colorectal cancer; and, the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT06780098___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MmE4NjoyMjJlNGIxOGI2Yzg0YmU1Y2IwYmEwNmVjZTA1NjI3ZGQ4NjQzMTVjZGNjYzQ3NTA5YjNmOWY5ZjRhZDUxNTc3OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=KEYMAKER-U01&amp;index=50&amp;md5=c31e8cce5dfdfdb72946000b04789777\" rel=\"nofollow\" shape=\"rect\">KEYMAKER-U01<\/a> sub-studies 01H\/01I (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2081eTiP___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YWQ2YToxZTAyODM0ZTEwYWM2ODcxZTA4ZTBmZWUwNTI3ZTRhYmFlMWRjMTFmMThkNGM0ZDkzYTUyYjUzMzhkZGY4MTU3OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2081eTiP&amp;index=51&amp;md5=5200d3a97bc4d2f07872a6b4f06ee8f1\" rel=\"nofollow\" shape=\"rect\">2081eTiP<\/a>) evaluating ifinatamab deruxtecan, raludotatug deruxtecan or docetaxel in patients with stage IV NSCLC.<\/p>\n<p>\nThe design of two additional early phase trials will be shared, including the <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT06780137___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NWM3YjoyYWQxODYzZWVkMmM4ZTRmMDQ5ZDY2MDYzNDEzMjc5MDUyNTA0ZDc0MDE0YmY1MWMwMzlhNGIyNjAzMmFmMThlOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=phase+1%2F2+trial&amp;index=52&amp;md5=89701ca8916a972767fcd267e209bf2f\" rel=\"nofollow\" shape=\"rect\">phase 1\/2 trial<\/a> (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2792TiP___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MmExOTpkYjY0NmUzOGI0MWQyNjY1ZTYwY2QxOGY1NDFkOGJjYTg3NTAyN2FkMjA0MzI4YWVkYjgzNWVkOTlhZWJhZWU4OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2792TiP&amp;index=53&amp;md5=b7214fc77daedaa3e024fb380b1aefcb\" rel=\"nofollow\" shape=\"rect\">2792TiP<\/a>) evaluating ifinatamab deruxtecan and gocatamig in patients with relapsed\/refractory ES-SCLC and a <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fclinicaltrials.gov%2Fstudy%2FNCT04388852___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZmIyNTo4NTMwZTFmZDE3NDUzZjE1N2QxNTJjYWIxMWQ5ODA3ZjFmOGQzNDg5ODY3MmY3NTBmZWEzMWExMTZlMDQ0N2U0OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=phase+1b+trial&amp;index=54&amp;md5=234f9d0e35116d0b34f0e088ece50fbc\" rel=\"nofollow\" shape=\"rect\">phase 1b trial<\/a> (<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D977P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MjUxZTo4OWZkMTU4NTQyYjdjMTFmMWMxY2QyZGVmNTcxMjcwNTQxNmUzOGI1ZTdlNjNlNTlkOGVkNDdjNjNjMmRkYjQyOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=977P&amp;index=55&amp;md5=7468029420f0f7671166632b691c37ab\" rel=\"nofollow\" shape=\"rect\">977P<\/a>) of valemetostat in combination with ipilimumab in patients with refractory genitourinary tumors, including prostate cancer, urothelial carcinomas and renal clear cell carcinoma.<\/p>\n<p>\n<b>Investor Briefing During ESMO<br \/>\n<br \/><\/b>Daiichi Sankyo will hold a virtual conference call for investors on Tuesday, October 21, 2025 from 8:00 to 9:30 am EDT \/ 9:00 to 10:30 pm JST. Executives from Daiichi Sankyo will provide an overview of the ESMO data.<\/p>\n<p>\n<b>Daiichi Sankyo Oral Presentations at ESMO<\/b><\/p>\n<table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl bwwidth100\">\n<tr>\n<td class=\"bwvertalignt bwtopsingle bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"2\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>Presentation Title<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwtopsingle bwsinglebottom bwrightsingle bwpadl0 bwrowaltcolor1 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>Author<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwtopsingle bwsinglebottom bwrightsingle bwpadl0 bwrowaltcolor1 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>Abstract<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwtopsingle bwsinglebottom bwrightsingle bwpadl0 bwrowaltcolor1 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>Presentation (CEST)<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"5\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>Breast<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTrastuzumab deruxtecan (T-DXd) vs trastuzumab emtansine (T-DM1) in patients with high-risk human epidermal growth factor receptor 2-positive (HER2+) primary breast cancer with residual invasive disease after neoadjuvant therapy: interim analysis of DESTINY-Breast05<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nC. Geyer<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3DLBA1___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MTI5MTo5MGYwNjEwYzEzYTZlNTM0OTc5MzIzNjQxYzAxNTdkOTM2YWRhYWNmOTcwNTE0MjI1NWVkYjkyMjA1ZTZiMTExOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=LBA1&amp;index=56&amp;md5=daa42d26d2e96683eadfd504fe52440c\" rel=\"nofollow\" shape=\"rect\">LBA1<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPresidential Symposium I<\/p>\n<p class=\"bwcellpmargin\">\nSaturday, October 18<\/p>\n<p class=\"bwcellpmargin\">\n4:30 \u2013 6:15 pm<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nDESTINY-Breast11: neoadjuvant trastuzumab deruxtecan alone (T-DXd) or followed by paclitaxel + trastuzumab + pertuzumab (T-DXd-THP) vs SOC for high-risk HER2+ early breast cancer<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nN. Harbeck<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D291O___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YWEwMzo5NzMzNzE0ZjRjZTM1NGRmOGYxYThkZGI1YjU2OGZhMjc3MzQ0NTIzZDE3YzU1NjY3MTQ1OTI5OGE5M2ViYTgwOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=291O&amp;index=57&amp;md5=af212b6dbd9a2f822e67f2463bb27eb5\" rel=\"nofollow\" shape=\"rect\">291O<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPresidential Symposium I<\/p>\n<p class=\"bwcellpmargin\">\nSaturday, October 18<\/p>\n<p class=\"bwcellpmargin\">\n4:30 \u2013 6:15 pm<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTrastuzumab deruxtecan (T-DXd) + pertuzumab vs taxane + trastuzumab + pertuzumab (THP) for patients with HER2+ advanced\/metastatic breast cancer: additional analyses of DESTINY-Breast09 in key subgroups of interest<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nS. Loibl<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3DLBA18___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MDQ2YTo3MTg0ZDNkZGRjZDVmMzM2ZjZlN2E2Y2IwZjljMDJhM2M5ZGQ5MGNlN2FlODQ1NGVmNDgzODNjNjJkZjQxZjhmOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=LBA18&amp;index=58&amp;md5=38dbaf8e610aef994bb43fd70c3d79c4\" rel=\"nofollow\" shape=\"rect\">LBA18<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nProffered Paper Session<\/p>\n<p class=\"bwcellpmargin\">\nSunday, October 19<\/p>\n<p class=\"bwcellpmargin\">\n8:30 \u2013 10:00 am<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nFirst-line datopotamab deruxtecan (Dato-DXd) vs chemotherapy in patients with locally recurrent inoperable or metastatic triple negative breast cancer for whom immunotherapy was not an option: primary results from the randomized, phase 3 TROPION-Breast02 trial<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nR. Dent<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fshow%2Fsession%2F115___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NWQ4ZTo0MGVhNTI5ZDYyYjRhNzU0NzM5ZDk3NzVlZGU3MGVhNDI1MTViOWI4ZGEyM2UwMjYzNmVjY2FlNzEwMzhkZmFlOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=LBA21&amp;index=59&amp;md5=fd1f2d9768fadd9cf747e41ab368c7dc\" rel=\"nofollow\" shape=\"rect\">LBA21<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nProffered Paper Session<\/p>\n<p class=\"bwcellpmargin\">\nSunday, October 19<\/p>\n<p class=\"bwcellpmargin\">\n8:30 \u2013 10:00 am<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nDatopotamab deruxtecan (Dato-DXd) + durvalumab as first-line treatment for unresectable locally advanced\/ metastatic triple negative breast cancer: final results from the phase 1b\/2 BEGONIA study<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nP. Schmid<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D555MO___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NWNmYjpmOWU5ZTFjOWQ4MjRhOTMxMWU1NzNhYzM3MTZkYjM3NjI4YjRjZThmZTI1ZDNkZWE5M2RjY2ZhODU1MzI5NDA1OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=555MO&amp;index=60&amp;md5=b31f88aa313acc5878182004ad56cdc7\" rel=\"nofollow\" shape=\"rect\">555MO<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nMini Oral Session<\/p>\n<p class=\"bwcellpmargin\">\nMonday, October 20<\/p>\n<p class=\"bwcellpmargin\">\n10:15 \u2013 11:45 am<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"2\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>Lung<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nIntracranial activity of ifinatamab deruxtecan (I-DXd) in patients with extensive-stage small cell lung cancer and baseline brain metastases: primary analysis of IDeate-Lung01<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nP. Rocha<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D2760MO___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZTI0NzplN2IxMjBlY2Y0Y2U2MjU0YjExYzQxNDM2NjM5YzVlZDUxNzNkYTllNTQzM2Y3NTU0NjYyOGVhOWY1ZGQ0ZmQzOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2760MO&amp;index=61&amp;md5=d6526656c8117898203221bc06cb976a\" rel=\"nofollow\" shape=\"rect\">2760MO<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nMini Oral Session<\/p>\n<p class=\"bwcellpmargin\">\nSaturday, October 18<\/p>\n<p class=\"bwcellpmargin\">\n4:30 \u2013 6:00 pm<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nUpdated results from a phase 1\/2 study of gocatamig for small cell lung cancer and other neuroendocrine cancers<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nH. Beltran<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D2758MO___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6Mzc3ZTowMDBlN2RlYjc0OTRmY2I2NWZmN2RiZTQzYmJmMTM0MzI3YzEyNzVmY2I1NDVhMDQ5ZWMwYWZlOTJiMjVjMjgzOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2758MO&amp;index=62&amp;md5=27a8c0c8ae82276d7facaa57d46c67ee\" rel=\"nofollow\" shape=\"rect\">2758MO<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nMini Oral Session<\/p>\n<p class=\"bwcellpmargin\">\nSaturday, October 18<\/p>\n<p class=\"bwcellpmargin\">\n4:30 \u2013 6:00 pm<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>Ovarian<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nRaludotatug deruxtecan (R-DXd) in patients with platinum-resistant ovarian cancer: primary analysis of the phase 2 dose- optimization part of the REJOICE-Ovarian01 study<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nI. Ray-Coquard<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3DLBA42___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NTcxMDo2ZjZlNWM5MzVmZmE0N2M0OGQ1OGZjN2VjYWY0MWJhMDhlNGMyOGMyNzAxYTc0YTU3MzExMWNhYjcxNDg4ZmE0OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=LBA42&amp;index=63&amp;md5=d385265ba4c42e417450999ab742405c\" rel=\"nofollow\" shape=\"rect\">LBA42<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nProffered Paper Session<\/p>\n<p class=\"bwcellpmargin\">\nSunday, October 19<\/p>\n<p class=\"bwcellpmargin\">\n2:45 \u2013 4:15 pm<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>Bladder<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nDatopotamab deruxtecan (Dato-DXd) + rilvegostomig in patients with locally advanced or metastatic urothelial cancer: results from the phase 2 TROPION-PanTumor03 study<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nS. Rha<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D3072MO___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NjhiODplMDZkNWM0YmFiNDQ5Y2ViMDQ4OGY0MjgxNjQyYjg4OWMwODdlZWExM2FjNzU5ZTNmYzJmNWQwN2E2ZGFlOGRkOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=3072MO&amp;index=64&amp;md5=f22aff746db0d32375ddd0987856807d\" rel=\"nofollow\" shape=\"rect\">3072MO<\/a><\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nMini Oral Session<\/p>\n<p class=\"bwcellpmargin\">\nFriday, October 17<\/p>\n<p class=\"bwcellpmargin\">\n4:00 \u2013 5:30 pm<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>CRC<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTrastuzumab deruxtecan (T\u2011DXd) in patients with HER2 positive (HER2+) metastatic colorectal cancer: final analysis of DESTINY-CRC02, a randomized, phase 2 trial<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nK. Raghav<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D737MO___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MWY0OToyZjA4MDVjNWJkMzE5MGRjZmRhY2JkZmZmNTUzYTljY2U3NTVjN2I4NGY5MjBkN2RiYTRhZmFkYzQ1NWVlOTk1OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=737MO&amp;index=65&amp;md5=4ee197c5aa7da64d92416e7db0f1fe9b\" rel=\"nofollow\" shape=\"rect\">737MO<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nMini Oral Session<\/p>\n<p class=\"bwcellpmargin\">\nSunday, October 19<\/p>\n<p class=\"bwcellpmargin\">\n2:45 \u2013 4:15 pm<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>PanTumor<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth60\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nDS-3939, a tumor-associated mucin 1 (TA-MUC1)-directed antibody drug conjugate (ADC), in patients with advanced\/metastatic solid tumors: initial results from a first-in-human study<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nM. Patel<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal%2Fpresentation%2Flist%3Fq%3D917O___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZTJiNDo4MDNmZGY5MDRkNjIxZDI1ZTMxNTk0NmJkNzQxZmRmZTIxZDBjODFmMmY3NTMyNGM2OGU1OTg0YTAyMGZjMDczOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=917O&amp;index=66&amp;md5=0bded0475ca33c7860eb1a5ea385b04b\" rel=\"nofollow\" shape=\"rect\">917O<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth18\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nProffered Paper Session<\/p>\n<p class=\"bwcellpmargin\">\nSunday, October 19<\/p>\n<p class=\"bwcellpmargin\">\n2:45 \u2013 4:20 pm<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n<b>Daiichi Sankyo Poster Presentations at ESMO<\/b><\/p>\n<table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl bwwidth100\">\n<tr>\n<td class=\"bwvertalignt bwtopsingle bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"2\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>Presentation Title<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwtopsingle bwsinglebottom bwrightsingle bwpadl0 bwrowaltcolor1 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>Author<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwtopsingle bwsinglebottom bwrightsingle bwpadl0 bwrowaltcolor1 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>Abstract<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwtopsingle bwsinglebottom bwrightsingle bwpadl0 bwrowaltcolor1 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<b>Presentation (CDT)<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"3\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>Breast<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nFinal real-world safety and effectiveness results of REALITY-01 study: trastuzumab deruxtecan (T-DXd) in patients received \u22652 prior treatment lines for HER2+ metastatic or unresectable breast cancer<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nJ. Pierga<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D539P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NTg2OTo1OGExMzY4MGI0OGRiNzM1NzUxNzU5NzBkNjBkYTRjODlmMmI4ZTQ1NjIxZTBmMDVjYmYxZDcyZjI5N2Y2MzNlOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=539P&amp;index=67&amp;md5=8eb99f35f72227df96f27ffb4f2c1909\" rel=\"nofollow\" shape=\"rect\">539P<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nThe effectiveness of post-trastuzumab deruxtecan (T-DXd) treatment regimens and the incidence of recurrent interstitial lung disease (ILD) in patients with HER2+ metastatic breast cancer who discontinued T-DXd due to ILD<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nJ. Tsurutani<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D540P%26r%3Dpt%257E36___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MTA3Mjo4YTg1ZTRlNzc4NzE1N2FkNWM0MzU0NmI2YTY1M2E2MmFkOGNjYmY2MDcyMDgwYmU0NjRlODU5YzNkOTdhNjZlOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=540P&amp;index=68&amp;md5=48219fde60e411c0a0b978890ed1c393\" rel=\"nofollow\" shape=\"rect\">540P<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nHERTHENA-Breast03: a phase 2, randomized, open-label study evaluating neoadjuvant patritumab deruxtecan + pembrolizumab before or after pembrolizumab + chemotherapy for early-stage TNBC or HR low+\/HER2\u2212 breast cancer<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nM. Danso<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D463eTiP___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ODRhYjo5OTY4ZWRjMjRkNDk2MGI3MTc1ZGY5OTVhMGY4MDkyZjg3ZWM1NDk1N2Y2OWM2ZDI0NTY3YWYzODViNGNiN2NkOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=463eTiP&amp;index=69&amp;md5=a38305711f210576c25aaff24694d778\" rel=\"nofollow\" shape=\"rect\">463eTiP<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nePoster<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"3\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>Lung<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPhase 1b study of valemetostat in combination with datopotamab deruxtecan (Dato-DXd) in advanced non-squamous non-small cell lung cancer: initial safety results<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nA. Spira<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2023P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YjE4YjpmYzExOGZiMDVhNjhiOTU4NDY0ZDEzMjFhMzU3ZmI2MmI4MWY4MzM4NTYzYjhlZjk1MGY5OWIxMjlkZmIzZWVmOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2023P&amp;index=70&amp;md5=a866fafda324ab707cd11b18d854324a\" rel=\"nofollow\" shape=\"rect\">2023P<\/a><\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nA phase 1b\/2 study of gocatamig (MK-6070; HPN328) and ifinatamab deruxtecan for relapsed\/refractory extensive-stage small cell lung cancer<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nJ. Sun<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2792TiP___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MmExOTpkYjY0NmUzOGI0MWQyNjY1ZTYwY2QxOGY1NDFkOGJjYTg3NTAyN2FkMjA0MzI4YWVkYjgzNWVkOTlhZWJhZWU4OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2792TiP&amp;index=71&amp;md5=a1009978deba1f8b088ad3617f86789e\" rel=\"nofollow\" shape=\"rect\">2792TiP<\/a><\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nKEYMAKER-U01 phase 2 substudies 01H\/01I: ifinatamab deruxtecan (I-DXd), raludotatug deruxtecan (R-DXd) or docetaxel in stage IV non-small cell lung cancer<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nE. Nadal<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2081eTiP___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YWQ2YToxZTAyODM0ZTEwYWM2ODcxZTA4ZTBmZWUwNTI3ZTRhYmFlMWRjMTFmMThkNGM0ZDkzYTUyYjUzMzhkZGY4MTU3OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2081eTiP&amp;index=72&amp;md5=36ce6e127e06a5e99a7c5fd2b281621e\" rel=\"nofollow\" shape=\"rect\">2081eTiP<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nePoster<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"4\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>Gastrointestinal<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTrastuzumab deruxtecan (T-DXd) vs ramucirumab plus paclitaxel in second-line treatment of patients with HER2+ unresectable\/metastatic gastric cancer\/gastroesophageal junction adenocarcinoma: additional data from DESTINY-Gastric04<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nF. Pietrantonio<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2099P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MTNiODpiMDBkMDQ1Y2FkN2I2MmU5YzJmZTExZTMzNjViYjFhZDA4NzM4NmQ1OWE3ZWY1Yzc0MjFiOTVlN2U0M2Y5NjI2OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2099P&amp;index=73&amp;md5=682de57963dcab76a43aefc0a9bca83c\" rel=\"nofollow\" shape=\"rect\">2099P<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTrastuzumab deruxtecan (T-DXd) in patients with HER2+ gastric cancer or gastroesophageal junction adenocarcinoma who received prior anti-HER2 treatment other than\/in addition to trastuzumab in DESTINY-Gastric06<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nZ. Peng<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2105P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZjU2MjphMTJlMTgxY2JhMGVkZTZmYmQzZDMwYmNkM2RhM2Y3MDA3OGM5ZDEzMGU4NjE4ZTcxOWY3NzA1ZDQzZjdhN2QwOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2105P&amp;index=74&amp;md5=11deab5d50e70bbf818ab7d93bff70b3\" rel=\"nofollow\" shape=\"rect\">2105P<\/a><\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nRisk of hepatitis B virus reactivation in patients with past or resolved HBV or inactive chronic HBV infection treated with trastuzumab deruxtecan (T-DXd) in the DESTINY-Gastric06<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nL. Shen<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D2175P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NWJlMjpjM2UwOGYzMmE2MTY1NjMwN2YxMGRmNGYyMTBjOWY3MDUzOTdkOTg1YWE2MDVhNGU0YzZhYmJlOWI0ODQ3YjlhOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=2175P&amp;index=75&amp;md5=6fc5d9adf0f9810f57cff4992ee4d493\" rel=\"nofollow\" shape=\"rect\">2175P<\/a><\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nRaludotatug deruxtecan in participants with gastrointestinal cancers: phase 2 REJOICE-GI01 trial<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nM. Ueno<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D1001TiP___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6ZjJlNzo4OTNlYjg2OWU4ZTQ0NTY2MWM0MmVmNjQzNGI5NThmMzM5OWU2NmY5MzE4ZTZmZjhhY2NiYjkzNjFlOTQxYmZhOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=1001TiP&amp;index=76&amp;md5=d6d58520758834dba25bc4ffbd5498ab\" rel=\"nofollow\" shape=\"rect\">1001TiP<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>Endometrial<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nA randomized phase 3 study of first-line trastuzumab deruxtecan (T-DXd) with rilvegostomig or pembrolizumab in patients with HER2 expressing, mismatch repair-proficient, primary advanced or recurrent endometrial cancer: DESTINY-Endometrial01\/GOG-3098\/ENGOT-EN24<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nB. Slomovitz<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D1223TiP___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6NTA4NzpkZmI3ZmMwYjliZmRlYjI2MDI2NTRlOGFjNmY1N2NjOTgwNzBmODk3OThlZTg2MjhlYjJiZTJjYTc0MjBlZDg3OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=1223TiP&amp;index=77&amp;md5=b4b2f8d1321f8c48a35ef083ee34037a\" rel=\"nofollow\" shape=\"rect\">1223TiP<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwrowaltcolor1\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0 bwvertalignm bwalignc bwwidth6\" colspan=\"1\" rowspan=\"3\">\n<p class=\"bwalignc bwcellpmargin\">\n<b>PanTumor<\/b><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTrastuzumab deruxtecan (T-DXd) for pretreated patients with HER2 expressing solid tumors: DESTINY-PanTumor02 part 1 final analysis<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nV. Makker<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D957P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6YTgzNDpiOWE4YzJiZGMwNTE0ZDBjMjliNGI2MjlkOTY0YzM1NGE0NjI0NDA1NWY5YTM0NWNiZGRhNjg0Yzc2Njk3MmFkOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=957P&amp;index=78&amp;md5=aaa1a4f28ea5202e9db6eeeb78ff48bc\" rel=\"nofollow\" shape=\"rect\">957P<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTrastuzumab deruxtecan (T-DXd) in pretreated patients with HER2 expressing solid tumors: exploratory biomarker analysis of DESTINY-PanTumor02 part 1<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nD. Oh<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D145P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6Nzg1ZjphNTkzZThmOTcxOTUwN2QwMTJlNGFkZDE0M2UzODhlNTRiZTFiZjIyYTY3ZDAxMjEzN2I4OTA5ZmVmZTk5NDk2OnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=145P&amp;index=79&amp;md5=8d723485ec1e73021df12610cd359c42\" rel=\"nofollow\" shape=\"rect\">145P<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth63\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nDS3201 (valemetostat), an EZH1\/2 inhibitor, with ipilimumab in patients with refractory genitourinary tumors<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth10\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nS. Goswami<\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth6\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n<a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___https%3A%2Fcslide.ctimeetingtech.com%2Fesmo2025%2Fattendee%2Fconfcal_2%2Fpresentation%2Flist%3Fq%3D977P___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MjUxZTo4OWZkMTU4NTQyYjdjMTFmMWMxY2QyZGVmNTcxMjcwNTQxNmUzOGI1ZTdlNjNlNTlkOGVkNDdjNjNjMmRkYjQyOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=977P&amp;index=80&amp;md5=96cd636206d8316bd14f9d3b620726dd\" rel=\"nofollow\" shape=\"rect\">977P<\/a><\/p>\n<\/td>\n<td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth15\" colspan=\"1\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nPoster Session<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n<b>About the ADC Portfolio of Daiichi Sankyo<br \/>\n<br \/><\/b>The Daiichi Sankyo ADC portfolio consists of seven ADCs in clinical development crafted from two distinct ADC technology platforms discovered in-house by Daiichi Sankyo.<\/p>\n<p>\nThe ADC platform furthest in clinical development is Daiichi Sankyo\u2019s DXd ADC Technology where each ADC consists of a monoclonal antibody attached to a number of topoisomerase I inhibitor payloads (an exatecan derivative, DXd) via tetrapeptide-based cleavable linkers. The DXd ADC portfolio currently consists of ENHERTU, a HER2 directed ADC, and DATROWAY, a TROP2 directed ADC, which are being jointly developed and commercialized globally with AstraZeneca. Patritumab deruxtecan (HER3-DXd), a HER3 directed ADC, ifinatamab deruxtecan (I-DXd), a B7-H3 directed ADC, and raludotatug deruxtecan (R-DXd), a CDH6 directed ADC, are being jointly developed and commercialized globally with Merck &amp; Co., Inc, Rahway, NJ, USA. DS-3939, a TA-MUC1 directed ADC, is being developed by Daiichi Sankyo.<\/p>\n<p>\nThe second Daiichi Sankyo ADC platform consists of a monoclonal antibody attached to a modified pyrrolobenzodiazepine (PBD) payload. DS-9606, a CLDN6 directed PBD ADC, is the first of several planned ADCs in clinical development utilizing this platform.<\/p>\n<p>\nIfinatamab deruxtecan, patritumab deruxtecan, raludotatug deruxtecan, DS-3939 and DS-9606 are investigational medicines that have not been approved for any indication in any country. Safety and efficacy have not been established.<\/p>\n<p>\n<b>About Daiichi Sankyo<br \/>\n<br \/><\/b>Daiichi Sankyo is an innovative global healthcare company contributing to the sustainable development of society that discovers, develops and delivers new standards of care to enrich the quality of life around the world. With more than 120 years of experience, Daiichi Sankyo leverages its world-class science and technology to create new modalities and innovative medicines for people with cancer, cardiovascular and other diseases with high unmet medical needs. For more information, please visit <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fprotect.checkpoint.com%2Fv2%2Fr01%2F___http%3A%2Fwww.daiichisankyo.com___.YzJ1OndlY29tbXVuaWNhdGlvbnM6YzpvOmQ3OTk3YzI4MDhiYTBhNTFjMWY3ODI0MGYyNmFhNWZkOjc6MzM5Mzo1ZjQ0NWU2ZDdjY2U4OGRmZDA4YmEwMWJkNzUzYjQzZmE3ZjQ1N2RiMmFhMTkyYWFjNmM4NDUzOGIyODgyNjEyOnA6RjpG&amp;esheet=54337288&amp;newsitemid=20251013032388&amp;lan=en-US&amp;anchor=www.daiichisankyo.com&amp;index=81&amp;md5=84d34e472bb5c4ae49090ccf4bfaf608\" rel=\"nofollow\" shape=\"rect\">www.daiichisankyo.com<\/a>.<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\n<b>Media Contacts:<\/b><\/p>\n<p>\n<b>Global\/US Media:<\/b><br \/>Jennifer Brennan<br \/>\n<br \/>Daiichi Sankyo<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;&#x61;&#105;lt&#x6f;&#x3a;&#106;&#101;n&#x6e;&#x69;&#102;&#101;r&#x2e;&#x62;&#x72;&#101;nn&#x61;&#x6e;&#64;&#100;a&#x69;&#x69;&#99;&#104;i&#x73;&#x61;&#110;&#107;y&#x6f;&#x2e;&#x63;&#111;m\" rel=\"nofollow\" shape=\"rect\">&#106;&#x65;n&#x6e;&#x69;&#102;&#x65;r&#46;&#x62;&#114;&#x65;n&#110;&#x61;n&#x40;d&#97;&#x69;i&#x63;&#x68;&#105;&#x73;a&#110;&#x6b;&#121;&#x6f;&#46;&#99;&#x6f;&#109;<\/a><br \/>+ 1 908 900 3183 (mobile)<\/p>\n<p>\n<b>Japan:<\/b><br \/>Daiichi Sankyo Co., Ltd.<br \/>\n<br \/><a target=\"_blank\" href=\"&#x6d;a&#x69;&#108;t&#x6f;&#58;&#x44;&#x53;-&#x50;&#82;_&#x6a;&#112;&#x40;&#100;a&#x69;&#105;c&#x68;&#105;&#x73;&#97;n&#x6b;&#121;&#x6f;&#x2e;c&#x6f;&#109;\" rel=\"nofollow\" shape=\"rect\">&#68;&#x53;&#45;&#x50;R&#x5f;j&#112;&#x40;&#100;&#x61;i&#x69;c&#104;&#x69;&#115;&#x61;n&#x6b;y&#111;&#x2e;&#99;&#x6f;m<\/a><\/p>\n<p>\n<b>Investor Relations Contact:<\/b><br \/><a target=\"_blank\" href=\"&#x6d;&#97;i&#x6c;&#116;o&#x3a;&#68;a&#x69;&#105;c&#x68;&#105;S&#x61;&#x6e;k&#x79;&#x6f;&#73;&#x52;&#x5f;&#106;&#x70;&#x40;&#100;a&#x69;&#105;c&#x68;&#105;s&#x61;&#110;k&#x79;&#111;&#46;&#x63;&#x6f;m\" rel=\"nofollow\" shape=\"rect\">D&#97;&#x69;&#x69;c&#104;&#105;&#x53;&#x61;n&#107;&#x79;&#x6f;I&#82;&#95;&#x6a;&#x70;&#64;&#100;&#x61;&#x69;i&#99;&#104;&#x69;&#x73;a&#110;&#x6b;&#x79;o&#46;&#99;&#x6f;&#x6d;<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Back-to-back Presidential Symposium presentations of ENHERTU from DESTINY-Breast11 and DESTINY-Breast05 demonstrate its potential to become a foundational treatment in curative-intent settings of HER2 positive early breast cancer Late-breaking data from TROPION-Breast02 showcase that DATROWAY is the first and only therapy to significantly improve overall survival versus chemotherapy as first-line treatment for patients with first-line metastatic &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/daiichi-sankyo-continues-to-transform-standards-of-care-for-patients-with-three-landmark-breast-cancer-trials-and-additional-data-across-industry-leading-adc-portfolio-at-esmo\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-62011","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Daiichi Sankyo Continues to Transform Standards of Care for Patients with Three Landmark Breast Cancer Trials and Additional Data Across Industry-Leading ADC Portfolio at ESMO - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/daiichi-sankyo-continues-to-transform-standards-of-care-for-patients-with-three-landmark-breast-cancer-trials-and-additional-data-across-industry-leading-adc-portfolio-at-esmo\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Daiichi Sankyo Continues to Transform Standards of Care for Patients with Three Landmark Breast Cancer Trials and Additional Data Across Industry-Leading ADC Portfolio at ESMO - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"Back-to-back Presidential Symposium presentations of ENHERTU from DESTINY-Breast11 and DESTINY-Breast05 demonstrate its potential to become a foundational treatment in curative-intent settings of HER2 positive early breast cancer Late-breaking data from TROPION-Breast02 showcase that DATROWAY is the first and only therapy to significantly improve overall survival versus chemotherapy as first-line treatment for patients with first-line metastatic ... 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