{"id":62664,"date":"2026-02-18T16:06:08","date_gmt":"2026-02-18T15:06:08","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/meridian-life-science-expands-ambient-stable-ngs-portfolio-with-the-launch-of-a-lyophilized-enzymatic-dna-fragmentation-kit\/"},"modified":"2026-02-18T16:06:08","modified_gmt":"2026-02-18T15:06:08","slug":"meridian-life-science-expands-ambient-stable-ngs-portfolio-with-the-launch-of-a-lyophilized-enzymatic-dna-fragmentation-kit","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/meridian-life-science-expands-ambient-stable-ngs-portfolio-with-the-launch-of-a-lyophilized-enzymatic-dna-fragmentation-kit\/","title":{"rendered":"Meridian Life Science Expands Ambient-Stable NGS Portfolio with the Launch of a Lyophilized Enzymatic DNA Fragmentation Kit"},"content":{"rendered":"<div>\n<p>\nThe new product reinforces Meridian\u2019s leadership in enzyme stabilization and enables simplified and decentralized Next-Generation-Sequencing sample preparation.<\/p>\n<p>CINCINNATI&#8211;(BUSINESS WIRE)&#8211;The Life Science division of Meridian Bioscience, Inc., a leading global provider of diagnostic testing solutions and life science raw materials, today announced the launch of its Lyophilized NGS Enzymatic DNA Fragmentation Kit. The kit is designed for ambient-temperature (15-25\u2070C) shipping and storage, eliminating the need for cold-chain requirements and helping laboratories simplify their NGS sample preparation workflows.<\/p>\n<p>\nThe launch of this new kit extends Meridian\u2019s enzyme stabilization strategy beyond PCR and isothermal amplification and into a critical step of NGS sample preparation, strengthening the company\u2019s leading position as a technology partner for assay developers, platform providers and emerging sequencing applications.<\/p>\n<p>\n<b>Removing Cold-Chain Constraints in NGS Sample Preparation<\/b><\/p>\n<p>\nTraditional NGS workflows rely on refrigerated reagents, which increases cost, handling complexity, and the risk of performance variability due to freeze-thaw cycles. This kit overcomes these limitations with a fully lyophilized formulation that remains stable at ambient temperatures and is rehydrated at the point of use, which reduces handling steps and supports consistent performance.<\/p>\n<p>\nThis kit is the only ambient-stable enzymatic DNA fragmentation solution commercially available and supports streamlined logistics, simplified laboratory operations, and a more robust workflow deployment across a wide range of sequencing environments.<\/p>\n<p>\n<b>Supporting the Shift Towards Decentralized Sequencing<\/b><\/p>\n<p>\nAs NGS expands beyond centralized laboratories, toward automated and point-of-need applications, reagent stability and logistics have become critical barriers to adoption. Meridian\u2019s new enzymatic fragmentation kit addresses these challenges and is designed to integrate with Meridian\u2019s lyophilized NGS library preparation chemistries, supporting emerging decentralized sequencing models where portability, automation, and ease of use are essential.<\/p>\n<p>\n<b>Consistent, Controlled Fragmentation<\/b><\/p>\n<p>\nFragmentation variability can impact library quality and downstream sequencing performance. Meridian\u2019s enzymatic fragmentation kit enables precise time-controlled fragmentation, allowing users to produce consistent and adjustable fragment sizes without the need for mechanical shearing instruments.<\/p>\n<p>\n<b>Simple Integration into NGS Workflows<\/b><\/p>\n<p>\nThe ready-to-rehydrate format supports:<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nAmbient-temperature storage and shipping<\/li>\n<li>\nReady-to-use formulation &#8211; no freeze-thaw cycles<\/li>\n<li>\nPrecise time-controlled enzymatic fragmentation<\/li>\n<li>\nCompatible with low-, medium-, and high-throughput workflows<\/li>\n<li>\nSuitable with automated workflows<\/li>\n<\/ul>\n<p>\nMeridian\u2019s Lyophilized NGS Enzymatic DNA Fragmentation Kit (MDX224) is compatible with established short-read library preparation workflows, including those used with Illumina\u00ae and Element Biosciences\u00ae sequencing platforms. Meridian can also support customers in adapting the kit to additional NGS platforms, with ongoing R&amp;D efforts focused on compatibility with emerging sequencing technologies.<\/p>\n<p>\nAssay and platform developers can integrate the kit into their own library preparation protocol enabling the creation of end-to-end ambient-stable library preparation workflows tailored to specific instruments and uses.<\/p>\n<p>\n\u201cOur new Lyophilized NGS Enzymatic DNA Fragmentation Kit demonstrates how our enzyme stabilization technology can deliver practical value for next-generation sequencing users. By eliminating the cold-chain requirements, we improve consistency and usability today, while laying the foundation for broader access to sequencing technologies as the NGS landscape continues to evolve,\u201d said Harald Ottenhof, Meridian\u2019s Executive Vice President, Life Science.<\/p>\n<p>\nFor more information on Lyophilized NGS Enzymatic DNA Fragmentation Kit and Meridian\u2019s NGS reagent portfolio, please visit: <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.meridianbioscience.com%2Flifescience%2Fproducts%2Fmolecular%2Flyophilized-ngs-enzymatic-dna-fragmentation-kit%2F&amp;esheet=54426518&amp;newsitemid=20260218011054&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.meridianbioscience.com%2Flyophilized-ngs-enzymatic-dna-fragmentation-kit%2F&amp;index=1&amp;md5=b2708f44506a41b46b2319e181cf5752\" rel=\"nofollow\" shape=\"rect\">https:\/\/www.meridianbioscience.com\/lyophilized-ngs-enzymatic-dna-fragmentation-kit\/<\/a><\/p>\n<p>\n<b>About Meridian Bioscience, Inc.<\/b><\/p>\n<p>\nMeridian is a fully integrated life science company that develops, manufactures, markets, and distributes a broad range of innovative diagnostic and life science products. We are dedicated to developing and delivering better solutions that provide answers with speed, accuracy, and simplicity, redefining the possibilities of life from discovery to diagnosis. Through discovery and development, we provide critical life science raw materials used in immunological and molecular tests for human, animal, plant, and environmental applications. Through diagnosis, we provide diagnostic solutions in areas including gastrointestinal and upper respiratory infections and blood lead level testing. We build relationships and provide solutions to hospitals, reference laboratories, research centers, veterinary testing centers, physician offices, diagnostics manufacturers, and biotech companies in more than 70 countries around the world. Meridian is a privately held company headquartered in Cincinnati, Ohio. Meridian\u2019s website address is <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.meridianbioscience.com%2F&amp;esheet=54426518&amp;newsitemid=20260218011054&amp;lan=en-US&amp;anchor=www.meridianbioscience.com&amp;index=2&amp;md5=13ed14a6bea03aea8b57c9d7035d3391\" rel=\"nofollow\" shape=\"rect\">www.meridianbioscience.com<\/a>.<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\nLucy Pillai<br \/>\n<br \/>Senior Director, Global Sales Operations and North American Sales<br \/>\n<br \/>Meridian Bioscience, Inc.<br \/>\n<br \/>Phone: 901.382.8716<br \/>\n<br \/>Email: <a target=\"_blank\" href=\"&#x6d;&#x61;&#x69;&#x6c;&#116;&#111;:in&#x66;&#x6f;&#x40;&#x6d;&#101;&#114;idi&#x61;&#x6e;&#x62;&#x69;&#111;&#115;&#99;ie&#x6e;&#x63;&#x65;&#x2e;&#99;&#111;&#109;\" rel=\"nofollow\" shape=\"rect\">&#x69;&#110;f&#x6f;&#64;m&#x65;&#114;i&#x64;&#105;a&#x6e;&#98;i&#x6f;&#x73;c&#x69;&#x65;&#110;&#x63;&#x65;&#46;&#x63;&#x6f;&#109;<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The new product reinforces Meridian\u2019s leadership in enzyme stabilization and enables simplified and decentralized Next-Generation-Sequencing sample preparation. CINCINNATI&#8211;(BUSINESS WIRE)&#8211;The Life Science division of Meridian Bioscience, Inc., a leading global provider of diagnostic testing solutions and life science raw materials, today announced the launch of its Lyophilized NGS Enzymatic DNA Fragmentation Kit. The kit is designed &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/meridian-life-science-expands-ambient-stable-ngs-portfolio-with-the-launch-of-a-lyophilized-enzymatic-dna-fragmentation-kit\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-62664","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Meridian Life Science Expands Ambient-Stable NGS Portfolio with the Launch of a Lyophilized Enzymatic DNA Fragmentation Kit - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/meridian-life-science-expands-ambient-stable-ngs-portfolio-with-the-launch-of-a-lyophilized-enzymatic-dna-fragmentation-kit\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Meridian Life Science Expands Ambient-Stable NGS Portfolio with the Launch of a Lyophilized Enzymatic DNA Fragmentation Kit - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"The new product reinforces Meridian\u2019s leadership in enzyme stabilization and enables simplified and decentralized Next-Generation-Sequencing sample preparation. 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