{"id":62775,"date":"2026-03-11T22:07:17","date_gmt":"2026-03-11T21:07:17","guid":{"rendered":"https:\/\/pharma-trend.com\/en\/landmark-study-shows-average-cost-savings-of-80000-per-child-and-overall-improved-health-outcomes-following-genedx-exome-and-genome-testing\/"},"modified":"2026-03-11T22:07:17","modified_gmt":"2026-03-11T21:07:17","slug":"landmark-study-shows-average-cost-savings-of-80000-per-child-and-overall-improved-health-outcomes-following-genedx-exome-and-genome-testing","status":"publish","type":"post","link":"https:\/\/pharma-trend.com\/en\/landmark-study-shows-average-cost-savings-of-80000-per-child-and-overall-improved-health-outcomes-following-genedx-exome-and-genome-testing\/","title":{"rendered":"Landmark Study Shows Average Cost Savings of $80,000 Per Child and Overall Improved Health Outcomes Following GeneDx Exome and Genome Testing"},"content":{"rendered":"<div>\n<p class=\"bwalignc\">\n<i>New data shows up to 61% reduction in healthcare costs for children with neurodevelopmental disorders in the 12 months following ExomeDx\u2122 and GenomeDx\u2122 testing, regardless of the test result<\/i><\/p>\n<p>GAITHERSBURG, Md.&#8211;(BUSINESS WIRE)&#8211;GeneDx (Nasdaq: WGS), the leader in rare disease diagnosis and improving health through the power of genomic data, today announced findings from the Genetic <span class=\"bwuline\">S<\/span>equencing <span class=\"bwuline\">A<\/span>nalysis has <span class=\"bwuline\">V<\/span>alue in <span class=\"bwuline\">E<\/span>conomic <span class=\"bwuline\">S<\/span>avings (SAVES)-Kids Study, a real-world data Health Economics and Outcomes Research (HEOR) analysis led by GeneDx that focuses on the economic impact of whole exome sequencing (WES) and whole genome sequencing (WGS) in children with neurodevelopmental disorders, like epilepsy and developmental delay and intellectual disability (DD\/ID). The data was unveiled today at the American College of Medical Genetics and Genomics (ACMG) Annual Meeting in Baltimore, MD.<\/p>\n<p><a href=\"https:\/\/mms.businesswire.com\/media\/20260311695167\/en\/2727212\/5\/General_Logo.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20260311695167\/en\/2727212\/22\/General_Logo.jpg\"><\/a><br \/><a href=\"https:\/\/mms.businesswire.com\/media\/20260311695167\/en\/2727212\/5\/General_Logo.jpg\"><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20260311695167\/en\/2727212\/21\/General_Logo.jpg\"><\/a><\/p>\n<p>\nThe study demonstrates that GeneDx\u2019s ExomeDx\u2122 and GenomeDx\u2122 significantly reduce total healthcare costs in the 12- and 24-months following testing for patients covered by private insurance and Medicaid.<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nSavings were primarily driven by fewer hospitalizations and reduced emergency room utilization \u2013 patterns consistent with accurate diagnoses and more targeted, high-value care after genomic testing.<\/li>\n<li>\nAdditionally, the study found that all test result types (positive, possible, and negative) offer significant average cost savings and improved health outcomes.<\/li>\n<\/ul>\n<p>\n\u201cThis data makes one thing undeniable \u2013 early exome and genome testing changes the trajectory of care regardless of test result,\u201d said Katherine Stueland, President and CEO of GeneDx. \u201cFor years, GeneDx has known that faster access to exome and genome sequencing shortens the diagnostic odyssey and drives more precise clinical action. Now we have clear, real-world evidence showing it also reduces avoidable hospitalizations, lowers emergency room utilization, and meaningfully decreases total healthcare spend \u2013 particularly in Medicaid populations where every dollar and every moment matters.\u201d<\/p>\n<p>\nFor children presenting with epilepsy:<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nAverage total healthcare costs decreased 61% from $130,048 per patient per year (PPPY) in the years leading up to GeneDx WES\/WGS to $50,798 PPPY in the 12 months following testing<\/li>\n<li>\nAverage reduction in healthcare costs of $79,250 PPPY<\/li>\n<li>\nReduced hospitalization costs were the largest contributor to these savings<\/li>\n<\/ul>\n<p>\nChildren with epilepsy covered by Medicaid showcased similar meaningful first-year economic and utilization improvements:<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nAverage reduction of total healthcare costs of 53% in the year after WES\/WGS compared to the year prior to testing, translating to approximately $50,000 in total healthcare cost savings<\/li>\n<li>\nSavings were the result of substantial declines in acute care utilization, with 80% fewer hospitalizations and 70% fewer emergency room visits in the year directly after testing<\/li>\n<li>\nDecrease in high-cost acute care was coupled with a moderate increase in outpatient and pharmacy costs, suggesting that healthcare resources were being better directed<\/li>\n<\/ul>\n<p>\nChildren with DD\/ID demonstrated the same trends in healthcare resource utilization and average cost savings:<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nTotal healthcare costs were reduced by 19%, representing approximately $9,000 in total healthcare cost savings in the first-year post-exome or genome testing<\/li>\n<li>\nSignificant reductions in acute care utilization, with 80% fewer hospitalizations and 50% fewer emergency room visits<\/li>\n<li>\nWhile outpatient costs increased by 38% and pharmacy costs increased by 37%, overall healthcare costs for patients with DD\/ID declined<\/li>\n<li>\nThis shift is consistent with better directed outpatient management and ongoing therapy care decisions informed by the WES\/WGS test result<\/li>\n<\/ul>\n<p>\nDespite clinical guidelines supporting WES\/WGS as a first-tier test, children with neurological disorders often are not tested when the onset of symptoms, like seizures, first begin. The SAVES-Kids HEOR study adds real-world evidence that WES\/WGS may help accelerate the transition from episodic, high-cost acute care to more planned outpatient and therapeutic pathways, underscoring the opportunity for health systems to realize greater value when exome and genome testing are implemented earlier in alignment with medical guidelines.<\/p>\n<p>\n\u201cExome and genome sequencing deliver better health outcomes and measurable cost savings. The standard of care must reflect that reality,\u201d said Linda Genen, MD, MPH, FAAP, Chief Medical Officer at GeneDx. \u201cThe earlier genomic testing is implemented, the faster children receive targeted management, and the more efficiently health systems and payors can allocate resources. The data is clear \u2013 genomic precision medicine is not just better care, it is smarter healthcare.\u201d<\/p>\n<p>\nAs the leader in rare disease diagnosis, GeneDx delivers the #1 genetic test and is the top choice of pediatric and genetic providers nationwide. GeneDx has delivered more rare disease diagnoses than any other organization in the world \u2013 a distinction made possible by GeneDx Infinity\u2122, the world\u2019s largest rare disease dataset of more than one million exomes and genomes and over 2.5 million tests. By combining patient insights from Komodo Health&#8217;s Healthcare Map<sup>\u00ae<\/sup> with data from GeneDx Infinity, GeneDx is uniquely positioned to help shape a smarter, more proactive healthcare system \u2013 improving outcomes for families across the country.<\/p>\n<p>\n<b>About GeneDx<br \/>\n<br \/><\/b>GeneDx\u2019s (Nasdaq: WGS) mission is to empower everyone to live their healthiest life through genomics. GeneDx combines unmatched clinical expertise, advanced technology, and the power of GeneDx Infinity\u2122 \u2013 the world\u2019s largest rare disease genomic dataset. This unparalleled foundation powers GeneDx\u2019s ExomeDx\u2122 and GenomeDx\u2122 tests \u2013 ranked #1 by expert geneticists and granted FDA Breakthrough Device designation \u2013 enabling clinicians to deliver precise, fast, and actionable diagnoses. GeneDx Infinity also fuels discovery for biopharma, with the most powerful AI-driven genomic intelligence. A genomics pioneer over the last 25 years, diagnosing more than 4,800 genetic diseases and publishing more than 1,000 research publications, GeneDx is building the network that will drive the future of genomic precision medicine. For more information, visit <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.genedx.com%2F&amp;esheet=54445301&amp;newsitemid=20260311695167&amp;lan=en-US&amp;anchor=genedx.com&amp;index=1&amp;md5=7f3a39fd9456d6e3bbda370213ba3daa\" rel=\"nofollow\" shape=\"rect\">genedx.com<\/a> and connect with us on <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fgenedx&amp;esheet=54445301&amp;newsitemid=20260311695167&amp;lan=en-US&amp;anchor=LinkedIn&amp;index=2&amp;md5=589490b7c16c8cc26f0aeb3485ea872d\" rel=\"nofollow\" shape=\"rect\">LinkedIn<\/a>, <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.facebook.com%2FGeneDxLab%2F&amp;esheet=54445301&amp;newsitemid=20260311695167&amp;lan=en-US&amp;anchor=Facebook&amp;index=3&amp;md5=31a882cf67715ead005508ea72f90833\" rel=\"nofollow\" shape=\"rect\">Facebook<\/a>, and <a target=\"_blank\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.instagram.com%2Fgenedxlab&amp;esheet=54445301&amp;newsitemid=20260311695167&amp;lan=en-US&amp;anchor=Instagram&amp;index=4&amp;md5=e1cc711872e83c7d797801abe1277c37\" rel=\"nofollow\" shape=\"rect\">Instagram<\/a>.<\/p>\n<p>\n<b>Forward Looking Statements<\/b><\/p>\n<p>\nThis press release may contain \u201cforward-looking statements\u201d within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements generally are identified by the words \u201cbelieve,\u201d \u201cproject,\u201d \u201cexpect,\u201d \u201canticipate,\u201d \u201cestimate,\u201d \u201cintend,\u201d \u201cstrategy,\u201d \u201cfuture,\u201d \u201copportunity,\u201d \u201cplan,\u201d \u201cmay,\u201d \u201cshould,\u201d \u201cwill,\u201d \u201cwould,\u201d \u201cwill be,\u201d \u201cwill continue,\u201d \u201cwill likely result,\u201d and similar expressions. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this press release, including but not limited to: (i) our ability to advance gene-disease discovery and implement plans to accelerate and unlock the full potential of precision medicine, (ii) the risk of downturns and a changing regulatory landscape in the highly competitive healthcare industry, (iii) the size and growth of the market in which we operate, (iv) our ability to pursue our new strategic direction. The foregoing list of factors is not exhaustive. A further list and description of risks, uncertainties and other matters can be found in the \u201cRisk Factors\u201d section of our Annual Report on Form 10-K for the fiscal year ended December 31, 2025, and other documents filed by us from time to time with the SEC. These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Forward-looking statements speak only as of the date they are made. Readers are cautioned not to put undue reliance on forward-looking statements, and we assume no obligation and do not intend to update or revise these forward-looking statements, whether as a result of new information, future events, or otherwise. We do not give any assurance that we will achieve our expectations.<\/p>\n<p> <b>Contacts<\/b> <\/p>\n<p>\n<b>Investor Relations Contact:<\/b><br \/><a target=\"_blank\" href=\"m&#97;&#x69;&#x6c;t&#111;&#58;&#x49;&#x6e;v&#101;&#115;&#x74;&#x6f;r&#115;&#x40;&#x47;&#x65;n&#101;&#x44;&#x78;&#46;&#99;&#111;&#x6d;\" rel=\"nofollow\" shape=\"rect\">In&#118;&#101;&#115;&#x74;&#x6f;&#x72;&#x73;&#64;G&#101;&#110;&#101;&#x44;&#x78;&#x2e;&#x63;om<\/a><\/p>\n<p>\n<b>Media Contact:<\/b><br \/><a target=\"_blank\" href=\"m&#97;&#x69;&#x6c;t&#111;&#x3a;&#x70;r&#101;&#x73;&#x73;&#64;&#103;&#x65;&#x6e;e&#100;&#x78;&#x2e;c&#111;&#109;\" rel=\"nofollow\" shape=\"rect\">&#x50;&#114;e&#x73;&#x73;&#64;G&#x65;&#x6e;&#101;D&#x78;&#x2e;&#99;o&#x6d;<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>New data shows up to 61% reduction in healthcare costs for children with neurodevelopmental disorders in the 12 months following ExomeDx\u2122 and GenomeDx\u2122 testing, regardless of the test result GAITHERSBURG, Md.&#8211;(BUSINESS WIRE)&#8211;GeneDx (Nasdaq: WGS), the leader in rare disease diagnosis and improving health through the power of genomic data, today announced findings from the Genetic &#8230; <span class=\"more\"><a class=\"more-link\" href=\"https:\/\/pharma-trend.com\/en\/landmark-study-shows-average-cost-savings-of-80000-per-child-and-overall-improved-health-outcomes-following-genedx-exome-and-genome-testing\/\">[Read more&#8230;]<\/a><\/span><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"entry","1":"post","2":"publish","3":"author-business","4":"post-62775","6":"format-standard","7":"category-industry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Landmark Study Shows Average Cost Savings of $80,000 Per Child and Overall Improved Health Outcomes Following GeneDx Exome and Genome Testing - Pharma Trend<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharma-trend.com\/en\/landmark-study-shows-average-cost-savings-of-80000-per-child-and-overall-improved-health-outcomes-following-genedx-exome-and-genome-testing\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Landmark Study Shows Average Cost Savings of $80,000 Per Child and Overall Improved Health Outcomes Following GeneDx Exome and Genome Testing - Pharma Trend\" \/>\n<meta property=\"og:description\" content=\"New data shows up to 61% reduction in healthcare costs for children with neurodevelopmental disorders in the 12 months following ExomeDx\u2122 and GenomeDx\u2122 testing, regardless of the test result GAITHERSBURG, Md.&#8211;(BUSINESS WIRE)&#8211;GeneDx (Nasdaq: WGS), the leader in rare disease diagnosis and improving health through the power of genomic data, today announced findings from the Genetic ... 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