Merck KGaA, Darmstadt, Germany Enters Collaboration and Option to License Agreement with Nerviano Medical Sciences to Develop Next-Generation PARP1 Selective Inhibitor
Not intended for UK- or Canada-based media NMS-293 is a next generation, orally available, brain-penetrant PARP1 selective inhibitor NMS-293 is currently studied in Phase I as monotherapy for the treatment of patients with BRCA-mutated tumors and in combination with temozolomide in recurrent glioblastoma Next generation PARP1 selective inhibitors could fill a significant unmet patient need … [Read more…]
