PureTech Meets Milestone of Achieving Oral Bioavailability of Allopregnanolone in Healthy Adults Dosed with LYT-300

LYT-300 achieved systemic blood levels approximately nine-fold greater compared to previous reports with oral allopregnanolone.1 Allopregnanolone is a neurosteroid with proven efficacy that is currently only approved as a 60-hour intravenous infusion. LYT-300, an orally administered prodrug of allopregnanolone, is designed to be differentiated from synthetic analogs, which may not replicate the full target engagement … [Read more…]

Beckley Psytech Announces Partnership With Ksana Health, Building on Digital Strategy to Deliver Optimised Patient Outcomes

Partnership will focus on the collection and analysis of digital biomarkers to identify signs of response and relapse in upcoming Phase 2 clinical trials Beckley Psytech aims to track and improve patient experience through an integrated, digitally-assisted treatment model OXFORD, England–(BUSINESS WIRE)–Beckley Psytech Limited, a private company dedicated to addressing neurological and psychiatric disorders through … [Read more…]

PureTech Reports Results from Phase 2 Study of LYT-100-COV in Post-Acute “Long” COVID with Respiratory Complications

No treatment effect observed in this patient population; substantial improvement in 6-minute walk test seen in both placebo and active groups Study adds to growing body of data supporting strong safety and tolerability profile of LYT-100 (deupirfenidone) Company will drive LYT-100 forward in other indications, with a focus on IPF where human clinical efficacy has … [Read more…]

Children’s Hospital Los Angeles: The Best Care for Kids in California and the West Coast

U.S. News & World Report’s annual hospital survey again ranks Children’s Hospital Los Angeles among the top 10 pediatric hospitals in the nation LOS ANGELES–(BUSINESS WIRE)–#childrenshealth–Children’s Hospital Los Angeles (CHLA) continues its streak of being California’s top hospital for pediatric care and specialty services, according to U.S. News & World Report’s 2022-23 Best Children’s Hospitals … [Read more…]

Alnylam Announces FDA Approval of AMVUTTRA™ (vutrisiran), an RNAi Therapeutic for the Treatment of the Polyneuropathy of Hereditary Transthyretin-Mediated Amyloidosis in Adults

– First and Only FDA-approved Treatment Demonstrating Reversal in Neuropathy Impairment with Subcutaneous Administration Once Every Three Months – – AMVUTTRA Met Primary and All Secondary Endpoints, with Significant Improvement in Polyneuropathy, Quality of Life and Gait Speed Relative to External Placebo – – Company Expects to Launch in Early July, with Value-Based Agreements to … [Read more…]

Rockley Photonics Set to Join Russell 3000® Index

OXFORD, England & PASADENA, Calif.–(BUSINESS WIRE)–$RKLY #RKLY–Rockley Photonics Holdings Limited (NYSE: RKLY), a global leader in photonics-based health monitoring and communications solutions, announced that it is set to join the broad-market Russell 3000® Index at the conclusion of the 2022 Russell indexes annual reconstitution, effective after the U.S. market opens on June 27, 2022, according … [Read more…]

Persad Center Announces Date for 2022 Annual Fundraising Gala, Art for Change; Launches Pilot Program to Support Artists

Funds Raised Will Support Mental Health Services for Pittsburgh’s LGBTQ+ Community PITTSBURGH–(BUSINESS WIRE)–Persad Center is hosting “Art for Change 2022” on Friday, September 9 at Stage AE on the North Shore. The event, Persad’s 35th Annual, is one of the region’s most significant art auctions. Proceeds support Persad Center’s mission of providing mental health services … [Read more…]

Humana to Donate Downtown Louisville Office Building to UofL

LOUISVILLE, Ky.–(BUSINESS WIRE)–Humana Inc. (NYSE: HUM) today announced that it will donate an office building in Downtown Louisville to the University of Louisville (UofL) in support of the activities of UofL’s Health Equity Innovation Hub. The 8-story building, located at 515 W. Market Street, was recently vacated by Humana and contains approximately 130,000 square feet … [Read more…]

Accolade Health, Inc. Announces Inducement Grants under Section 303A.08 of the NYSE Listed Company Manual

NEW YORK–(BUSINESS WIRE)–Accolade Health, Inc. (“Accolade”) (NYSE: OSCR), the first health insurance company built on a full stack technology platform, announced that on June 8, 2022 the Compensation Committee of Accolade’s Board of Directors approved the grant of inducement restricted stock unit awards covering 992,382 Class A shares of Accolade’s common stock to 29 new … [Read more…]

CONMED Completes Acquisition of In2Bones Global, Inc.

LARGO, Fla.–(BUSINESS WIRE)–CONMED Corporation (NYSE: CNMD) today announced that it has completed its previously announced acquisition of privately-held In2Bones Global Inc. Headquartered in Memphis, Tennessee, In2Bones is a global developer, manufacturer, and distributor of medical devices for the treatment of disorders and injuries of the upper (hand, wrist, elbow) and lower (foot and ankle) extremities. … [Read more…]